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| 1 | Pyridine Nucleotide Cycling and Control of Intracellular Redox State in Relation to Poly (ADP-Ribose) Polymerase Activity and Nuclear Localization of Glutathione during Exponential Growth of Arabidopsis Cells in Culture显示文摘Pyridine 核苷酸, ascorbate 和谷胱甘肽是在植物房间的主要氧化还原作用代谢物,与在细胞的氧化还原作用动态平衡和房间周期的规定的特定的角色。然而,代谢物在指数的生长期间分享的这些的规定和他们在细胞周期的精确功能尚待被描绘。在在文化的 Arabidopsis 房间的指数的生长期间的许多 ascorbate,谷胱甘肽,和 pyridine 核苷酸的现在的分析为每这些氧化还原作用水池的微分规定提供证据。Ascorbate 早很充满生长周期,但是谷胱甘肽在这个点是低的。到 dehydroascorbate 的细胞的 ascorbate 和到谷胱甘肽二硫化物比率的减少的谷胱甘肽(GSH ) 高、不变,但是 pyridine 核苷酸分享大部分在指数的生长的时期上被氧化并且一旦生长停止了,仅仅变得更多减少。谷胱甘肽水池增加了与同时 poly (自动数据处理核糖) 聚合酶(PARP ) 活动并且一次由 transcriptome 信息是的高房间周期活动随许多 PARP1 和 PARP2 mRNAs 的增加显示了。在在细胞质和原子核之间的 GSH 的细胞内部的划分的显著变化被观察。由冲淡的指数的生长阶段的扩展或改变导致的媒介在谷胱甘肽和菸碱腺嘌 dinucleotide 增加,氧化形式( NAD ) -plus-nicotinamide 腺嘌 dinucleotide ,减少的形式( NADH )水池并且到更高的 NAD/NADH 比率但是菸碱腺嘌 dinucleotide 磷酸盐,氧化形式( NADP ) -plus-nicotinamide 腺嘌 dinucleotide 磷酸盐,减少的形式( NADPH )水池尺寸,和 NAPD/NADPH 比率是影响的少得多。在指数的生长阶段结束了以前, ascorbate,谷胱甘肽,和 pyridine 核苷酸水池和 PARP 活动减少了。我们断定在生长周期期间处于细胞内部的氧化还原作用状态有显著变化,但是氧化还原作用动态平衡被主要氧化还原作用 pyridine 核苷酸,谷胱甘肽,和 ascorbate 水池的相互影响维持。在 PARP 表示和活动和 GSH 累积并且发现那 GSH 能被招募到原子核之间的关联建议在氧化还原作用规定和原子酶活动之间的一种关系。 | Till K. Pellny Vittoria Locato Pedro Diaz Vivancos Jelena Markovic Laura De Gara Federico V. Pallardo Christine H. Foyer | 2009 | Molecular Plant2009，2，3： | 4 |
| 2 | 高血压患者肾素血管紧张素系统阻断的血浆分子标志:肾损害与初发蛋白尿的新预测指标显示文摘蛋白尿是一个与心血管病密切相关的危险因素,也是一般人群的首位死亡原因。虽然已经明确肾素血管紧张素系统(renin-angiotensin system,RAS)阻断剂能延缓高血压患者初发蛋白尿进展、减少蛋白尿排出,但仍不能忽视高血压患者发生初发蛋白尿的比例。 | Baldan-Martin M Mourino-Alvarez L Gonzalez-Calero L Moreno-Luna R Sastre-Oliva T Ruiz-Hurtado G Segura J Lopez JA Vazquez J Vivanco F Alvarez-Llamas G Ruilope LM de la Cuesta F Barderas MG 赵狄 练桂丽 | 2016 | 中华高血压杂志2016，24，6： | 2 |
| 3 | How plants communicate using the underground information superhighway显示文摘 | Harsh Pal Bais Sang-Wook Park Tiffany L Weir Ragan M Callaway Jorge M Vivanco | 2003 | Trends in Plant Science2003，，1： | 2 |
| 4 | Poststroke Dementia: Clinical Features and Risk Factors显示文摘 | Raquel Barba Susana Martínez-Espinosa Elena Rodríguez-García Margarita Pondal José Vivancos Teodoro Del Ser | 2000 | Stroke: Journal of the American Heart Association2000，，7： | 2 |
| 5 | Factors that impact health-related quality of life in adults with celiac disease:A multicenter study显示文摘AIM: To evaluate the factors involved in the impairment of health-related quality of life (HRQOL) in patients with celiac disease.METHODS: A multicenter, cross-sectional prospective study was performed in patients with celiac disease who completed two HRQOL questionnaires: the gastrointestinal quality of life index (GIQLI) and the EuroQol-5D (EQ).RESULTS: Three hundred and forty patients (163 controlled with a gluten-free diet, and 177 newly diagnosed with a normal diet) were included. The GIQLI score was significantly better in patients on a gluten-free diet (GFD) than in non-treated patients on their usual diet, both in terms of the overall score (3.3 vs 2.7, respectively; P < 0.001), as well as on the individual questionnaire dimensions. Both the preference value of the EQ as the visual analogue scale were significantly better in treated than in non-treated patients (0.93 vs 0.72 P < 0.001 and 80 vs 70 P < 0.001, respectively). Variables significantly associated with a worse HRQOL score were female gender, failure to adhere to a GFD, and symptomatic status.CONCLUSION: In untreated celiac disease, the most important factors that influence patient perception of health are the presence of symptoms and a normal diet. HRQOL improves to levels similar to those described in the general population in celiac disease patients well controlled with a GFD. | F Casellas L Rodrigo J López Vivancos S Riestra C Pantiga JS Baudet F Junquera V Puig Diví C Abadia M Papo J Gelabert JR Malagelada | 2008 | World Journal of Gastroenterology2008，14，1： | 2 |
| 6 | Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain显示文摘 | Hammond R Vivancos V Naeem A | 2005 | Development2005，132，20： | 1 |
| 7 | Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors 显示文摘 | Mellinghoff IK Wang MY Vivanco I | 2005 | N Engl J Med2005，353，19： | 1 |
| 8 | The phosphatidylinositol 3 - kinase AKT pathway in human cancer 显示文摘 | Vivanco I Sawyers CL | 2002 | Nat Rev Cancer2002，2，7： | 1 |
| 9 | Bio- geographical variation in community response to root allelochem- istry : novel weapons and exotic invasion 显示文摘 | VIVANCO JM BAIS HP STERMITZ FR | 2004 | Ecology Letters2004，7，4： | 1 |
| 10 | Plant litter decomposition in a semi-arid ecosystem controlled by photodegradation显示文摘 | Austin AT Vivanco L | 2006 | Nature2006，，442： | 1 |
| 11 | The phosphatidylinositol 3-Kinase AKT pathway in human cancer 显示文摘 | Vivanco I Sawyers C L | 2002 | Nat Rev Cancer2002，2，7： | 1 |
| 12 | Intraspecific and interspecific interactions mediated by a phytotoxin,(-)-catechin,secreted by the roots of Centaurea maculosa显示文摘 | Tiffany L Weir Harsh Pal Bais Jorge M Vivanco | 2003 | Journal of Chemical Ecology2003，29，11： | 1 |
| 13 | The phosphatidylinositol 3-kinase-AKT pathway in human cancer显示文摘 | Vivanco I Sawyers C L | 2002 | Nat Rev Cancer2002，2，7： | 1 |
| 14 | Analysis of factors affecting the high-speed side milling of hardened die steels显示文摘 | J Vivancos C J Luis J A Orliz | 2005 | Journal of Materials Processing Technology2005，，163： | 1 |
| 15 | Biochemical and physiological mechanisms mediated by allelochemicals显示文摘 | Weir T L Park S W Vivanco J M | 2004 | Current Opinion in Plant Biology2004，7，： | 1 |
| 16 | Biochemical and physiologi- cal mechanisms mediated by allelochemicals 显示文摘 | Weir T L Park S W Vivanco J M | 2004 | Curr Opin Plant Biol2004，7，4： | 1 |
| 17 | Plant litter decomposition in a semi-arid ecosystem controlled by photodegradation显示文摘 | Austin A T Vivanco L | | 0，，： | 1 |
| 18 | Biochemical and physio-logical mechanisms mediated by allelochemicals 显示文摘 | WEIR T L PARK S W VIVANCO J M | 2004 | Current 0-pinion in Plant Biology2004，7，4： | 1 |
| 19 | The phosphatidylinositol 3-Kinase Akt pathway in human cancer 显示文摘 | Vivanco I Sawyers CL | 2002 | Nat Rev Cancer2002，2，7： | 1 |
| 20 | Safety study of long-term video-electroencephalogram monitoring显示文摘 | Ley M Vivanco R Massot A | 2014 | Neurologia2014，29，1： | 1 |
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