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| 1 | Developing a donation after cardiac death risk index for adult and pediatric liver transplantation显示文摘AIM To identify objective predictive factors for donor after cardiac death(DCD) graft loss and using those factors, develop a donor recipient stratification risk predictive model that could be used to calculate a DCD risk index(DCD-RI) to help in prospective decision making on organ use.METHODS The model included objective data from a single institute DCD database(2005-2013, n = 261). Univariate survival analysis was followed by adjusted Cox-regressional hazard model. Covariates selected via univariate regression were added to the model via forward selection, significance level P = 0.3. The warm ischemic threshold was clinically set at 30 min. Points were given to each predictor in proportion to their hazard ratio. Using this model, the DCD-RI was calculated. The cohort was stratified to predict graft loss risk and respective graft survival calculated.RESULTS DCD graft survival predictors were primary indication for transplant(P = 0.066), retransplantation(P = 0.176), MELD > 25(P = 0.05), cold ischemia > 10 h(P = 0.292) and donor hepatectomy time > 60 min(P = 0.028).According to the calculated DCD-RI score three risk classes could be defined of low(DCD-RI < 1), standard(DCD-RI 2-4) and high risk(DCD-RI > 5) with a 5 years graft survival of 86%, 78% and 34%, respectively.CONCLUSION The DCD-RI score independently predicted graft loss(P < 0.001) and the DCD-RI class predicted graft survival(P < 0.001). | Shirin Elizabeth Khorsandi Emmanouil Giorgakis Hector Vilca-Melendez John O'Grady Michael Heneghan Varuna Aluvihare Abid Suddle Kosh Agarwal Krishna Menon Andreas Prachalias Parthi Srinivasan Mohamed Rela Wayel Jassem Nigel Heaton | 2017 | World Journal of Transplantation2017,7,3: | 3 |
| 2 | Liver transplantation in patients over 60 and 65 years: An evaluation of long‐term outcomes and survival显示文摘 | Timothy J.S. Cross Charalambos G. Antoniades Paolo Muiesan Thawab Al‐Chalabi Varuna Aluvihare Kosh Agarwal Bernard C. Portmann Mohammed Rela Nigel D. Heaton John G. O’Grady Michael A. Heneghan | 2007 | Liver Transpl2007,,10: | 1 |
| 3 | Tolerance, suppression and the fetal allograft显示文摘 | Varuna R. Aluvihare Marinos Kallikourdis Alexander G. Betz | 2005 | Journal of Molecular Medicine2005,,2: | 1 |
| 4 | Review ofmathematical modeling on latent heat thermal energystorage systems using phase-change material显示文摘 | Prashant Verma Varuna Singal S K | 2008 | Renewable and Sustainable Energy Reviews2008,,12: | 1 |
| 5 | Utility and safety of temporary pacing using active fixation leads and externalized re-usable permanent pacemakers after lead extraction显示文摘 | Hiro Kawata Victor Pretorius Huy Phan Siva Mulpuru Varuna Gadiyaram Jigar Patel Dawna Steltzner David Krummen Gregory Feld Ulrika Birgersdotter-Green | 2013 | Europace2013,,9: | 1 |
| 6 | B cells and professional APCs recruit regulatory T cells via CCL4 显示文摘 | Bystry Richard S Aluvihare Varuna Welch Katie A | 2001 | Nature Immunology2001,2,12: | 1 |
| 7 | The role of regulatory T cells in alloantigen tolerance 显示文摘 | Varuna R A Alexander G B | 2006 | Immunological Reviews2006,212,: | 1 |
| 8 | The impact of inflammatory bowel disease post‐liver transplantation for primary sclerosing cholangitis显示文摘 | Deepak Joshi Ingvar Bjarnason Ajay Belgaumkar John O’Grady Abid Suddle Michael A. Heneghan Varuna Aluvihare Mohammed Rela Nigel Heaton Kosh Agarwal | 2011 | Liver Int2011,,1: | 1 |
| 9 | Evaluating the Efficiency of Cadmium Removal by Alginate Hydrogels from Water Using 5,7-Dibromo-8-hydroxyquinoline as a Complexing Reagent显示文摘Cadmium toxicity in wastewater is a rising concern due to industries like batteries,metallurgy,electroplating,plastic stabilizers,and pigments.The quantitative detection of Cd^(2+)and its remediation from wastewater samples are of major concern from an environmental point of view.In the present work,an effective spectrophotometric method has been reported using 5,7-dibromo-8-hydroxyquinoline(DBHQ)as a complexing agent for Cd^(2+).This method has advantages like using recyclable,less toxic solvents and easy sample preparation.The limit of detection,limit of quantification,and sensitivity of the proposed method were found to be 33.30,36.70 mg L^(−1),and 2×10^(−3),respectively.The DBHQ method was validated using atomic absorption spectroscopy,and the recovery percentage was more than 98%.These results indicate that DBHQ can be effectively used for monitoring Cd^(2+)in aqueous systems.The method developed was further employed for monitoring Cd^(2+)adsorption on calcium alginate(AL)hydrogels.Batch adsorption studies were done to optimize parameters of Cd^(2+)removal using AL hydrogels,and the data obtained were used for kinetic and thermodynamic studies.Kinetic studies indicated that the pseudo-first-order model showed better fitting,and thermodynamic studies showed Freundlich-like adsorption.The maximum adsorption capacity of Cd^(2+)on AL hydrogels was found to be 56.45 mg g^(−1).The validation studies of DBHQ were performed using statistical analysis methods like t-tests and one-way variance. | Abhijit B.Phalke Varuna S.Watwe Sunil D.Kulkarni Preeti S.Kulkarni | 2023 | Precision Chemistry2023,1,9: | 0 |
| 10 | Synthesis of 3,5-diarylisoxazoles under solvent-free conditions using iodobenzene diacetate显示文摘A simple and effcient method has been developed for conversion of chalcone oximes to 3,5-diaryl isoxazoles in excellent yields under solvent-free conditions.The synthesized compounds were characterized by infrared spectroscopy,1H NMR,13C NMR and HRMS. | Kondapalli Venkata Gowri Chandra Sekhar Thripuraribhatla Venkata Naga Varuna Tara Sasank Hunsur Nagendra Nagesh Narva Suresh Kalaga Mahalakshmi Naidu Amaroju Suresh | 2013 | Chinese Chemical Letters2013,24,12: | 0 |