|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Multiligament knee injuries with associated tibial plateau fractures: A report of two cases显示文摘The management of a combination of fracture and multiligament knee injury(MKI) in traumatic knee injury remains controversial, and there are evolving treatment recommendations. Currently, there are no studies focusing on older adult patients with MKI's in combination with tibia fractures. As a result, there is no well-established treatment algorithm for older adult patients with these complex injuries. We report two cases of MKI's with concomitant fractures in patients fifty years of age or older. Both patients were treated surgically for their associated tibial plateau fractures, but were managed with conservative treatment of the multiligamentous knee injuries. We also provide a review of the literature and guidelines for older adult patients with these types of complex traumatic injuries. Early to mid term acceptable outcomes were achieved for both patients through surgical fixation of the tibial plateau fracture and conservative treatment of the ligament injuries. We propose a comprehensive treatment algorithm for management of these complex injuries. | Vani J Sabesan Paul J Danielsky Abby Childs Tom Valikodath | 2015 | World Journal of Orthopedics2015，6，3： | 14 |
| 2 | Colon cancer and the epidermal growth factor receptor:Current treatment paradigms,the importance of diet,and the role of chemoprevention显示文摘Colorectal cancer represents the third most common and the second deadliest type of cancer for both men and women in the United States claiming over 50000 lives in 2014. The 5-year survival rate for patients diagnosed with metastatic colon and rectal cancer is < 15%. Early detection and more effective treatments are urgently needed to reduce morbidity and mortality of patients afflicted with this disease. Here we will review the risk factors and current treatment paradigms for colorectal cancer, with an emphasis on the role of chemoprevention as they relate to epidermal growth factor receptor(EGFR) blockade. We will discuss how various EGFR ligands are upregulated in the presence of Western diets high in saturated and N-6 polyunsaturated fats. We will also outline the various mechanisms of EGFR inhibition that are induced by naturally occurring chemopreventative agents such as ginseng, green tea, and curcumin. Finally, we will discuss the current role of targeted chemotherapy in colon cancer and outline the limitations of our current treatment options, describing mechanisms of resistance and escape. | Baldeep Pabla Marc Bissonnette Vani J Konda | 2015 | World Journal of Clinical Oncology2015，6，5： | 7 |
| 3 | Redundant CAMTA Transcription Factors Negatively Regulate the Biosynthesis of Salicylic Acid and N-Hydroxypipecolic Acid by Modulating the Expression of SARD1 and CBP60g显示文摘Two signal molecules, salicylic acid (SA) and N-hydroxypipecolic acid (NHP), play critical roles in plant immunity. The biosynthetic genes of both compounds are positively regulated by master immune-regulating transcription factors SARD1 and CBP60g. However, the relationship between the SA and NHP pathways is unclear. CALMODULIN-BINDING TRANSCRIPTION FACTOR 1 (CAMTA1), CAMTA2, and CAMTA3 are known redundant negative regulators of plant immunity, but the underlying mechanism also remains largely unknown. In this study, through chromatin immunoprecipitation and electrophoretic mobility shift assays, we uncovered that CBP60g is a direct target of CAMTA3, which also negatively regulates the expression of SARD1, presumably via an indirect effect. The autoimmunity of camta3-1 is suppressed by sard1 cbp60g double mutant as well as ald1 and fmo1, two single mutants defective in NHP biosynthesis. Interestingly, a suppressor screen conducted in the camta1/ 2/ 3 triple mutant background yielded various mutants blocking biosynthesis or signaling of either SA or NHP, leading to nearly complete suppression of the extreme autoimmunity of camta1/ 2/ 3, suggesting that the SA and NHP pathways can mutually amplify each other. Together, these results reveal that CAMTAs repress the biosynthesis of SA and NHP by modulating the expression of SARD1 and CBP60g, and that the SA and NHP pathways are coordinated to optimize plant immune response. | Tongjun Sun Jianhua Huang Yan Xu Vani Verma Beibei Jing Yulin Sun Alberto Ruiz Orduna Hainan Tian Xingchuan Huang Shitou Xia Laurel Schafer Reinhard Jetter Yuelin Zhang Xin Li | 2020 | Molecular Plant2020，13，1： | 5 |
| 4 | 胶管胶带用硫化剂和防老剂显示文摘越来越高的汽车发动机温度对在汽车中使用的胶管和胶带用聚合物提出了更严格的要求。本文综述了胶管和胶带中使用的聚合物,并针对提高耐热、耐屈挠疲劳和耐臭氧老化性能讨论了每一种聚合物用的硫化体系和防老剂搭配。 | Sinha D P Jablonowski Tom Ohm Bob Vanis Vern 黄向前 | 2002 | 橡胶工业2002，49，12： | 2 |
| 5 | Effects of fluoride accumulation on some enzymes of brain and gastrocnemium musule of mice显示文摘 | Vani ML Reddy KP | 2000 | fluoride2000，33，1： | 1 |
| 6 | Plasma Leptin is not ass-ociated within- sulin resistance and proinsulin in non-diabetic South Asian Indians显示文摘 | SNEHALATHA C RAMACHANDRAN A SATYA- VANI K~ | 1998 | Diabet Met1998，15，： | 1 |
| 7 | 'the Effect of Price and Entry Regulation on Airline Output,Capacity and Efficiency' 显示文摘 | Arthur S de Vany | 1975 | The Bell Journal of Economics1975，6，1： | 1 |
| 8 | A Modified Fluorimetric Method for Determination of Hydrogen Peroxide Using Homovanillic Acid Oxidation Principle显示文摘 | Biswaranjan Paital Vani Nilakantan | 2014 | BioMed Research International2014，，： | 1 |
| 9 | Alteration in chloro-plast structure and thylakoid membrane compositiondue to in vivo heat treatment of rice seedlings: corre-lation with the functional changes显示文摘 | Vani B Saradhi P P Mohanty P | 2001 | Journal of PlantPhysiology2001，158，58： | 1 |
| 10 | Foaming properties of selected plant and animal显示文摘 | Vani B Zayas J F | 1995 | Journal of Food Science1995，60，5： | 1 |
| 11 | ASGE Technology Status Evaluation Report Wireless Capsule Endoscopy显示文摘 | Amy Wang Subhas Banerjee Bradley A. Barth Yasser M. Bhat Shailendra Chauhan Klaus T. Gottlieb Vani Konda John T. Maple Faris Murad Patrick R. Pfau Douglas K. Pleskow Uzma D. Siddiqui Jeffrey L. Tokar Amy Wang Sarah A. Rodriguez | 2013 | Gastrointestinal Endoscopy2013，，： | 1 |
| 12 | In vitro and in vivo adhesion testing of mucoadhesive drug delivery systems显示文摘 | Vani G Rao YM | 1999 | Drug Development and Industrial Pharmacy1999，25，5： | 1 |
| 13 | Effect of fluoride accumulation on some enzymesof brain and gastrocnemius muscle of mice显示文摘 | Vani ML Teddy KP | 2000 | Fluoride2000，30，1： | 1 |
| 14 | Endometrial ex- pression of steroid receptors in postmenopausal hormone re- placement therapy users: relationship to bleeding patterns 显示文摘 | Vani S Critchley H O Fraser I S | 2008 | J Faro Plann Reprod Health Care2008，34，1： | 1 |
| 15 | The market for motion pictures:Rank,revenue,and survival显示文摘 | De Vany A Walls W.D | | 0，，： | 1 |
| 16 | A Single-Center Experience of Endoscopic Submucosal Dissection Performed in a Western Setting显示文摘 | Gabriel D. Lang Vani J. A. Konda Uzma D. Siddiqui Ann Koons Irving Waxman | 2015 | Digestive Diseases and Sciences2015，，2： | 1 |
| 17 | Working Capital Management: A Study of Maharashtra's Bulk Drugs Listed Companies 显示文摘 | Rakesh Yadav Ms Vani Kamath Dr Pradip Manjrekar | 2009 | Chemical Business2009，，1： | 1 |
| 18 | Effects of fluoride accumulation on some enzymes of brain and gastrocnemium musule of mice显示文摘 | Vani ML Reddy KP | | 0，，01： | 1 |
| 19 | Evaluating the older patient with cancer: understanding frailty and the geriatric assessment 显示文摘 | Sumanta KP Vani K Arti H | 2010 | CA Cancer J Clin2010，60，： | 1 |
| 20 | Protective effect of bacoside A on cigarette smoking-induced brain mitochondrial dysfunction in rats显示文摘 | ANBARASI K VANI G DEVI C S | 2005 | J Environ Pathol Toxicol Oncol2005，24，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员