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| 1 | Endoscopic management of Crohn's strictures显示文摘Symptomatic intestinal strictures develop in more than one third of patients with Crohn's disease(CD) within 10 years of disease onset. Strictures can be inflammatory, fibrotic or mixed and result in a significant decline in quality of life, frequently requiring surgery for palliation of symptoms. Patients under the age of 40 with perianal disease are more likely to suffer from disabling ileocolonic disease thus may have a greater risk for fibrostenotic strictures. Treatment options for fibrostenotic strictures are limited to endoscopic and surgical therapy. Endoscopic balloon dilatation(EBD) appears to be a safe, less invasive and effective alternative modality to replace or defer surgery. Serious complications are rare and occur in less than 3% of procedures. For non-complex strictures without adjacent fistulizaation or perforation that are less than 5 cm in length, EBD should be considered as first-line therapy. The aim of this review is to present the current literature on the endoscopic management of small bowel and colonic strictures in CD, which includes balloon dilatation, adjuvant techniques of intralesional injection of steroids and anti-tumor necrosis factor, and metal stent insertion. Short and long-term outcomes, complications and safety of EBD will be discussed. | Talat Bessissow Jason Reinglas Achuthan Aruljothy Peter L Lakatos Gert Van Assche | 2018 | World Journal of Gastroenterology2018，24，17： | 10 |
| 2 | European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease显示文摘 | J.F. Rahier S. Ben-Horin Y. Chowers C. Conlon P. De Munter G. D’Haens E. Domènech R. Eliakim A. Eser J. Frater M. Gassull M. Giladi A. Kaser M. Lémann T. Moreels A. Moschen R. Pollok W. Reinisch M. Schunter E.F. Stange H. Tilg G. Van Assche N. Viget B. Vu | 2009 | Journal of Crohn’s and Colitis2009，，2： | 3 |
| 3 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Current management显示文摘 | A. Dignass G. Van Assche J.O. Lindsay M. Lémann J. S?derholm J.F. Colombel S. Danese A. D’Hoore M. Gassull F. Gomollón D.W. Hommes P. Michetti C. O’Morain T. ?resland A. Windsor E.F. Stange S.P.L. Travis | 2010 | Journal of Crohn’s and Colitis2010，，1： | 2 |
| 4 | Anti-tumor necrosis factor treatment restores the gut barrier in Crohn’s disease显示文摘 | Peter Suenaert Veerle Bulteel Liesbeth Lemmens Maja Noman Benny Geypens Gert Van Assche Karel Geboes Jan L Ceuppens Paul Rutgeerts | 2002 | The American Journal of Gastroenterology2002，，8： | 2 |
| 5 | Influence of high NaC1 and NH4C1 salt levels on methano- genie associations显示文摘 | de Baere L A Devocht M Van Assche P Verstraete W | 1984 | Water Res1984，18，5： | 1 |
| 6 | Fetal growth restriction and consequences for the offspring in animalmodels 显示文摘 | Holemans K Aerts L Van Assche | 2003 | J Soc Gynecol Invest2003，10，： | 1 |
| 7 | Low taurine,ganma aminobutyric acid and camosine in plasma of diabetic pregnant rats: consequences for the offspring显示文摘 | Aerts L Van Assche F A | 2001 | J Perinat Med2001，29，1： | 1 |
| 8 | Severe systemic hypertension during pregnancy显示文摘 | Van Assche FA Spits B Vansteelant L | 1989 | Am J Cardiol1989，63，6： | 1 |
| 9 | The risk of post-operative complications associated with infliximab therapy for Crohn’s disease: a controlled cohort study显示文摘 | Marchal L D’Haens G Van Assche G | 2004 | Aliment Pharmacol Ther2004，19，7： | 1 |
| 10 | Taurine and taurine-deficieney in the perinatal period显示文摘 | Aerts L Van Assche FA | 2002 | J Perinatal Med2002，30，4： | 1 |
| 11 | Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn' s disease显示文摘 | Baert F Moortgat L Van Assche G Belgian Inflammatory Bowel Disease Research Group North- Holland Gut Club | 2010 | Gastroenterology2010，138，2： | 1 |
| 12 | Fetal growth and long-term consequences in animal models of growth retardation显示文摘 | HOLEMANS K AERTS L VAN ASSCHE F A | | 0，，02： | 1 |
| 13 | Long-term consequences for offspring of diabetes during pregnancy显示文摘 | van ASSCHE FA HOLEMANS K AERTS L | | 0，，： | 1 |
| 14 | Effect of material char- acteristics and/or surface topography on biofilm development 显示文摘 | Teughels W Van Assche N Sliepen l | 2006 | Clinical Oral Implants Research2006，17，2： | 1 |
| 15 | The risk of postoperative complications associated with infliximab therapy for C rohn's disease: a controlled cohort study 显示文摘 | Marchal L D' Haens G Van Assche G | 2004 | Aliment Pharmacol Ther2004，19，7： | 1 |
| 16 | Maternal diabetes during pregnancy: consequences for the offspring 显示文摘 | Aerts L Holemans K Van Assche F A | 1990 | Diabetes Metab Rev1990，6，3： | 1 |
| 17 | Attachment in old age :theoretical assumptions,empirical findings and implica- tions for clinical practice 显示文摘 | Van Assche L Luyten P Bruffaerts R | 2013 | Clin Psychol Rev2013，33，1： | 1 |
| 18 | The endocrine pancreas in virgin and pregnant offspring of diabetic pregnant rats 显示文摘 | Aerts L Vercruysse L Van Assche F A | 1997 | Diabetes Res Clin Praet1997，38，： | 1 |
| 19 | Cancer risk in im- mune-mediated inflammatory diseases ( IMID ) 显示文摘 | Beyaert R Beaugerie L Van Assche G | 2013 | Mol Cancer2013，12，1： | 1 |
| 20 | Low taurine,gamma-aminobutyric acid and carnosine levels in plasma of diabetic pregnant rats:consequences for the offspring显示文摘 | Aerts L Van Assche FA | 2001 | J Perinat Med2001，29，： | 1 |
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