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| 1 | Diagnostic imaging and radiation exposure in inflammatorybowel disease显示文摘Diagnostic imaging plays a key role in the diagnosis and management of inflammatory bowel disease(IBD). However due to the relapsing nature of IBD, there is growing concern that IBD patients may be exposed to potentially harmful cumulative levels of ionising radiation in their lifetime, increasing malignant potential in a population already at risk. In this review we explore the proportion of IBD patients exposed to high cumulative radiation doses, the risk factors associated with higher radiation exposures, and we compare conventional diagnostic imaging with newer radiation-free imaging techniques used in the evaluation of patients with IBD. While computed tomography(CT) performs well as an imaging modality for IBD, the effective radiation dose is considerably higher than other abdominal imaging modalities. It is increasingly recognised that CT imaging remains responsible for the majority of diagnostic medical radiation to which IBD patients are exposed. Magnetic resonance imaging(MRI) and small intestine contrast enhanced ultrasonography(SICUS) have now emerged as suitable radiation-free alternatives to CT imaging, with comparable diagnostic accuracy. The routine use of MRI and SICUS for the clinical evaluation of patients with known or suspected small bowel Crohn's disease is to be encouraged wherever possible. More provision is needed for out-of-hours radiation-free imaging modalities to reduce the need for CT. | Nekisa Zakeri Richard CG Pollok | 2016 | World Journal of Gastroenterology2016,22,7: | 4 |
| 2 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010,16,2: | 4 |
| 3 | European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease显示文摘 | J.F. Rahier S. Ben-Horin Y. Chowers C. Conlon P. De Munter G. D’Haens E. Domènech R. Eliakim A. Eser J. Frater M. Gassull M. Giladi A. Kaser M. Lémann T. Moreels A. Moschen R. Pollok W. Reinisch M. Schunter E.F. Stange H. Tilg G. Van Assche N. Viget B. Vu | 2009 | Journal of Crohn’s and Colitis2009,,2: | 3 |
| 4 | Hepatitis B Virus Limits Response of Human Hepatocytes to Interferon-α in Chimeric Mice显示文摘 | Marc Lütgehetmann Till Bornscheuer Tassilo Volz Lena Allweiss Jan–Hendrick Bockmann Joerg M. Pollok Ansgar W. Lohse Joerg Petersen Maura Dandri | 2011 | Gastroenterology2011,,7: | 2 |
| 5 | Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor,ENMD-2076,against multiple myeloma显示文摘 | WANG X J SINN A L POLLOK K | 2010 | Br J Haematol2010,150,3: | 1 |
| 6 | PET imaging and optical imaging with D-lueiferin methyl es- ter and D-luciferin methyl ether of luciferase gene expression in tumor xenografts of living mice 显示文摘 | Wang J-Q Pollok K E Cai S | 2006 | Bioorganic & Medicinal Chemistry Letters2006,16,2: | 1 |
| 7 | Peptidomies of identified neurons demonstrates a highly differentiated expression pattern of FXPRLamides in the neureendoerine system of an insect显示文摘 | Predel R Eckert M Pollok E | 2007 | J Comp Neurol2007,500,3: | 1 |
| 8 | The cerebral oscillatory network ofvoluntary tremor 显示文摘 | Pollok B Gross J Dirks M | 2004 | Physiol2004,554,3: | 1 |
| 9 | A theoretically optimized method for cord blood stem cell cryopreservation显示文摘 | Woods E J Liu J Pollok K | 2003 | J of Hemato and Stem Cell Res2003,12,: | 1 |
| 10 | Tissue engineering显示文摘 | Pollok JK Vaeanti JP | 1996 | Semin Pediatr Surg1996,5,3: | 1 |
| 11 | 4-1BB T-cell antigen binds to mature B cells and macrophages and costimulates anti-m-primed splenic B cells显示文摘 | Pollok KE Kim Y-J Hurtado J | 1994 | Eur J Immunol1994,2436,: | 1 |
| 12 | Functional analysis of Tcell antigen 4-1BB in activated intestinal intra-epithelial T lymphocytes显示文摘 | Zhou Z Pollok KE Kim KK | 1994 | Immunol Lett1994,41,23: | 1 |
| 13 | Lentiviral vectors pseudotyped with glycoproteins from Ross River and vesicular stomatitis viruses: variable transduction related to cell type and culture conditions 显示文摘 | Kahl CA Pollok K Haneline LS | 2005 | Mol Ther2005,11,3: | 1 |
| 14 | Patients with sold tumors treated with high-temperature whole body hyperthermia show a redistribution d native/memory T-cell subtypes 显示文摘 | Atanackovic D pollok K Faltz C | 2006 | Am J Physiol Regal Integrcomp Physiol2006,290,3: | 1 |
| 15 | Echoes from childhoodi?mitation in Gilles de la Tourette Syndrome显示文摘 | FinisJ Moczydlowski A Pollok B | 2012 | Mov Disord2012,27,4: | 1 |
| 16 | Tissue engineering显示文摘 | Pollok JM Vacanti JP | 1996 | Semin Pediatr Surg1996,5,3: | 1 |
| 17 | In vivo protection of hematopoietic cells from alkylator-mediated DNA damage显示文摘 | Pollok KE | 2003 | Curr Hematol Rep2003,2,4: | 1 |
| 18 | Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum 显示文摘 | Agranoff D Fernandez-Reyes D Papadopoulos MC Rojas SA Herbster M Loosemore A Tarelli E Sheldon J Schwenk A Pollok R Rayner CF Krishna S | 2006 | Lancet2006,368,: | 1 |
| 19 | Interrelations of breed type, USDA quality grade, cooking method and degree of doneness on consumer evaluations of beef in Dallas and San Antonio, Texas, USA 显示文摘 | McKenna D R Lorenzen C L Pollok K D | 2004 | Meat Science2004,66,2: | 1 |
| 20 | Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma 显示文摘 | WANG X SINN A L POLLOK K | 2010 | Br J Haematol2010,150,3: | 1 |