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| 1 | Magnetic Resonance Elastography for the Noninvasive Staging of Liver Fibrosis显示文摘 | Laurent Huwart Christine Sempoux Eric Vicaut Najat Salameh Laurence Annet Etienne Danse Frank Peeters Leon C. ter Beek Jacques Rahier Ralph Sinkus Yves Horsmans Bernard E. Van Beers | 2008 | Gastroenterology2008，，1： | 4 |
| 2 | European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease显示文摘 | J.F. Rahier S. Ben-Horin Y. Chowers C. Conlon P. De Munter G. D’Haens E. Domènech R. Eliakim A. Eser J. Frater M. Gassull M. Giladi A. Kaser M. Lémann T. Moreels A. Moschen R. Pollok W. Reinisch M. Schunter E.F. Stange H. Tilg G. Van Assche N. Viget B. Vu | 2009 | Journal of Crohn’s and Colitis2009，，2： | 3 |
| 3 | Propylthiouracyl-induced severe liver toxicity:An indication for alanine aminotransferase monitoring?显示文摘Propylthiouracyl (PTU)-related liver toxicity is likely to oc- cur in about 1% of treated patients. In case of acute or subacute hepatitis, liver failure may occur in about one third. We report two further cases of PTU-induced sub- acute hepatitis, in whom the delay between occurrence of liver damage after the initiation of treatment, the un- derestimation of its severity and the delayed withdrawal of the drug were all likely responsible for liver failure. The high incidence of liver toxicity related to PTU, its potential severity and delayed occurrence after initiation of treatment are in favor of monthly alanine aminotrans- ferase monitoring, at least during the first six months of therapy. | M Benyounes C Sempoux C Daumerie J Rahier AP Geubel | 2006 | World Journal of Gastroenterology2006，12，38： | 3 |
| 4 | Second European evidence-based consensus on the prevention,diagnosis and management of opportunistic infections in inflammatory boweldisease显示文摘 | Rahier JF Magro F Abreu C | 2014 | J Crohns Colitis2014，8，6： | 1 |
| 5 | Glucose Metabolism in 105 Children and Adolescents After Pancreatectomy for Congenital Hyperinsulinism显示文摘 | Beltrand Jacques Caquard Marylène Arnoux Jean-Baptiste Laborde Kathleen Velho Gilberto Verkarre Virginie Rahier Jacques Brunelle Francis Nihoul-Fékété Claire Saudubray Jean-Marie Robert Jean-Jacques de Lonlay Pascale | 2012 | Diabetes Care2012，，2： | 1 |
| 6 | 14-Aza- camptothecin: a potent water-soluble topoisomerase I poison显示文摘 | Cheng K Rahier NJ Eisenhauer BM | 2005 | J Am Chem Soc2005，127，3： | 1 |
| 7 | Influence of mix composition on the extent of autogenous crack healing by continued hydration or calcium carbonate formation显示文摘 | Kim Van Tittelboom Elke Gruyaert Hubert Rahier Nele De Belie | 2012 | Construction and Building Materials2012，，： | 1 |
| 8 | Increased lymphatic vessel density and lymphangiogenesis in inflammatory bowel disease显示文摘 | Rahier JF De Beauce S Dubuquoy L | 2011 | Aliment Pharmacol Ther2011，34，5： | 1 |
| 9 | Focal and diffuse forms of congenital hyperinsulinism:the keys for differential diagnosis显示文摘 | Sempoux C Guiot Y Jaubert F Rahier J | 2004 | Endocr Pathol2004，15，3： | 1 |
| 10 | Biogenesis, molecular regula- tion and function of plant isoprenoids 显示文摘 | Bouvier F Rahier A Camara B | 2005 | Prog Lipid Res2005，44，： | 1 |
| 11 | Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infeetions in inflammatory boweldisease European Crohn's and Colitis Organisation (ECCO) 显示文摘 | Rahier JF Magro F Abreu C | 2014 | J Crohns Colitis2014，8，6： | 1 |
| 12 | Congenital hyperinsulinism显示文摘 | Jean-Baptiste Arnoux Pascale de Lonlay Maria-Joao Ribeiro Khalid Hussain Oliver Blankenstein Klaus Mohnike Vassili Valayannopoulos Jean-Jacques Robert Jacques Rahier Christine Sempoux Christine Bellanné Virginie Verkarre Yves Aigrain Francis Jaubert Franc | 2010 | Early Human Development2010，，5： | 1 |
| 13 | Camptothecin:current perspectives显示文摘 | THOMAS C J RAHIER N J HECHT S M | 2004 | Bioorg Med Chem2004，12，7： | 1 |
| 14 | Does enemy-free space for eggs contribute to a leaf beetle's oviposition preference for a nutritionally inferior host plant 显示文摘 | Ballaheni P Wlodarczyk M Rahier M | 2001 | Functional Ecology2001，15，3： | 1 |
| 15 | Camptothecin: current perspectives 显示文摘 | Thomas C J Rahier N J Hecht S M | 2004 | Bioorg Med Chem2004，12，7： | 1 |
| 16 | Preserved vascular homograft for revascularization of pediatric liver transplant: a clinical, histological, and bacteriological study 显示文摘 | Martinez JA Rigamonti W Rahier J | 1999 | Transplantation1999，68，5： | 1 |
| 17 | HACD1,a regulator of membrane composition and fluidity,promotes myoblast fusion and skeletal muscle growth显示文摘The reduced diameter of skeletal myofibres is a hallmark of several congenital myopathies,yet the underlying cellular and molecular mechanisms remain elusive.In this study,we investigate the role of HACD1/PTPLA,which is involved in the elongation of the very long chain fatty acids,in muscle fibre formation.In humans and dogs,HACD1 deficiency leads to a congenital myopathy with fibre size disproportion associated with a generalized muscleweakness.Throughanalysis of HACD1-deficient Labradors,Hacd1-knockout mice,and Hacd1-deficient myoblasts,we provide evidence that HACD1 promotes myoblast fusion during muscle development and regeneration.We further demonstrate that in normal differentiating myoblasts,expression of the catalytically active HACD1 isoform,which is encoded by a muscle-enriched splice variant,yields decreased lysophosphatidylcholine content,a potent inhibitor of myoblast fusion,and increased concentrations of≥C18 and monounsaturated fatty acids of phospholipids.These lipid modifications correlate with a reduction in plasma membrane rigidity.In conclusion,we propose that fusion impairment constitutes a novel,non-exclusive pathological mechanism operating in congenital myopathies and reveal that HACD1 is a key regulator of a lipid-dependent muscle fibre growth mechanism. | Jordan Blondelle Yusuke Ohno Vincent Gache Stephane Guyot Sebastien Storck Nicolas Blanchard-Gutton Ines Barthelemy Gemma Walmsley Anaelle Rahier Stephanie Gadin Marie Maurer Laurent Guillaud Alexandre Prola Arnaud Ferry Genevieve Aubin-Houzelstein Jean Demarquoy Frederic Relaix Richard JPiercy Stephane Blot Akio Kihara Laurent Tiret Fanny Pilot-Storck | 2015 | Journal of Molecular Cell Biology2015，7，5： | 1 |
| 18 | Influence of Chamber Design and Operating Conditions on the Washing Efficiency of a Filter显示文摘 | G Rahier & J Hermia | 1988 | J Filter & Separation Sep/Otc1988，，： | 1 |
| 19 | Biogenesis, molecular regulation and function of plant Isoprenoids 显示文摘 | Bouvier F Rahier A Camara B | 2005 | Prog Lipid Res2005，44，： | 1 |
| 20 | Three-dimensional incompressible viscoelasticity in large strains:formulation and numerical approximation显示文摘 | Le Tallec P Rahier C Kaiss A | 1993 | Comput Methods Appl Mech Eng1993，109，： | 1 |
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