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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Improved clinical outcome using polytetrafluoroethylene-coated stents for tips: Results of a randomized study显示文摘 | Christophe Bureau Juan carlos Garcia-Pagan Philippe Otal Gilles Pomier-Layrargues Valérie Chabbert Carlos Cortez Pierre Perreault Jean marie Péron Juan G. Abraldes Louis Bouchard José Ignacio Bilbao Jaume Bosch Hervé Rousseau Jean pierre Vinel | 2004 | Gastroenterology2004，，2： | 3 |
| 3 | Plasticity of Human Adipose Lineage Cells Toward Endothelial Cells: Physiological and Therapeutic Perspectives显示文摘 | Valérie Planat-Benard Jean-Sébastien Silvestre Béatrice Cousin Mireille André Maryse Nibbelink Radia Tamarat Michel Clergue Carole Manneville Corinne Saillan-Barreau Micheline Duriez Alain Tedgui Bernard Levy Luc Pénicaud Louis Casteilla | 2004 | Circulation: Journal of the American Heart Association2004，，5： | 2 |
| 4 | Kisspeptin Mediates the Photoperiodic Control of Reproduction in Hamsters显示文摘 | Florent G. Revel Michel Saboureau Mireille Masson-Pévet Paul Pévet Jens D. Mikkelsen Valérie Simonneaux | 2006 | Current Biology2006，，17： | 2 |
| 5 | Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation显示文摘T-cell protein tyrosine phosphatase(TC-PTP)has a critical role in the development of the immune system and has been identified as a negative regulator of inflammation.Single-nucleotide polymorphisms in the TC-PTP locus have been associated with increased susceptibility to inflammatory bowel diseases(IBDs)in patients.To further understand how TC-PTP is related to IBDs,we investigated the role of TC-PTP in maintaining the intestinal epithelial barrier using an in vivo genetic approach.Intestinal epithelial cell(IEC)-specific deletion of TC-PTP was achieved in a mouse model at steady state and in the context of dextran sulphate sodium(DSS)-induced colitis.Knockout(KO)of TC-PTP in IECs did not result in an altered intestinal barrier.However,upon DSS treatment,IECspecific TC-PTP KO mice displayed a more severe colitis phenotype with a corresponding increase in the immune response and inflammatory cytokine profile.The absence of TC-PTP caused an altered turnover of IECs,which is further explained by the role of the tyrosine phosphatase in colonic stem cell(CoSC)proliferation.Our results suggest a novel role for TC-PTP in regulating the homeostasis of CoSC proliferation.This supports the protective function of TC-PTP against IBDs,independently of its previously demonstrated role in intestinal immunity. | Stéphanie Bussières-Marmen Valérie Vinette Jeremy Gungabeesoon Isabelle Aubry Luis Alberto Pérez-Quintero Michel L Tremblay | 2018 | Cellular & Molecular Immunology2018，15，4： | 1 |
| 6 | The influence of dust stan- dards on the prevalence and severity of coal worker's pneumoconiosis at autopsy in the United States of America 显示文摘 | Val V Douglas P Landsittel EL | 2011 | Arch Pathol Lab Med2011，135，12： | 1 |
| 7 | The span length and crosssectional design affect values of strength显示文摘 | Alander P Lassila LV Val ittu PK | | 0，，04： | 1 |
| 8 | Between subjects variability in haemoglobin and dose are not associated with the erythropoiesis-stimulating agent used to treat anaemia in dialysis: a meta-analysis显示文摘 | Pérez-Ruixo J J Cucala-Ramos M Garcia-Gonzalo E Del Val Romero B Valveny N | 2013 | Br J Clin Pharmacol2013，75，： | 1 |
| 9 | miR-203 represses 'sternness' by repressing DeltaNp63 显示文摘 | A M Lena R Shalom-Feuerstein P Rivetti di Val Cervo | 2008 | Cell Death Differ2008，15，7： | 1 |
| 10 | The marine planning framework for South Australia:a new ecosystem-based zoning policy for marine management显示文摘 | Val D Rosemary P Jon E | 2008 | Marine Policy2008，32，： | 1 |
| 11 | Analysis of enantiomers in biological matrices by charged cyclodextrin- mediated capillary zone electrophoresis in column - coupling arrangement with capillary isotachophoresis 显示文摘 | MIKUS P KUBACAK P VAL'A'SKOV'A I | 2006 | Talanta2006，70，： | 1 |
| 12 | miR- 203 represses 'sternness' by repressing DehaNp63 显示文摘 | Lena AM Shalom-Feuerstein R Rivetti di Val Cervo P | 2008 | Cell Death Differ2008，15，7： | 1 |
| 13 | Optimisation of wave energy extraction with the Archimedes wave swing显示文摘 | VAL(E)RIO D BEIR(A)O P S(A)DA COSTA J | | 0，，17： | 1 |
| 14 | Probabilistic evaluation of initiation time of chloride-induced corrosion显示文摘 | Val D V Trapper P A | 2008 | Reliability Engineering & System Safety2008，93，3： | 1 |
| 15 | p63-microRNA feed- back in keratinocyte senescence显示文摘 | Rivetti di Val Cervo P Lena AM Nieoloso M | 2012 | Proc Natl Acad Sci USA2012，109，4： | 1 |
| 16 | Probabilistic evaluation of initiation time of chloride-induced corrosion 显示文摘 | Val D V Trapper P A | 2008 | Reliability Engineering and System Safety2008，93，3： | 1 |
| 17 | Motor complications in Parkinson disease:a prospective follow-up study显示文摘 | Garcia Ruiz P J Meseguer E Del Val J | 2004 | Clin Neumpharmacol2004，27，： | 1 |
| 18 | miR-203 represses 'sternness'by repressing DehaNp63显示文摘 | Lena AM Shalom-Feuerstein R Rivetti di Val Cervo P | 2008 | Cell Death Differ2008，15，7： | 1 |
| 19 | Synthesis and structure investigation of alloys with fullerence and nanotube inclusions显示文摘 | CHERNOZATONSKII L A VAL’CHUK K P KISELEV N A | 1997 | Carbon1997，35，6： | 1 |
| 20 | p63 in epithelial development显示文摘 | Candi E Cipollone R Rivetti Di Val Cervo P | 2008 | Cell Mol Life Sci2008，65，20： | 1 |
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