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202篇 您的检索式:作者名="Otal"
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1Rescue associating liver partition and portal vein ligation for staged hepatectomy after portal embolization: Our experience and literature review显示文摘AIM To report a single-center experience in rescue associating liver partition and portal vein ligation for staged hepatectomy(ALPPS), after failure of previous portal embolization. We also performed a literature review.METHODS Between January 2014 and December 2015, every patient who underwent a rescue ALPPS procedure in Toulouse Rangueil University Hospital, France, was included. Every patient included had a project of major hepatectomy and a previous portal vein embolization(PVE) with insufficient future liver remnant to body weight ratio after the procedure. The ALPPS procedure was performed in two steps(ALPPS-1 and ALPPS-2), separated by an interval phase. ALPPS-2 was done within 7 to 9 d after ALPPS-1. To estimate the FLR, a computed tomography scan examination was performed 3 to 6 wk after the PVE procedure and 6 to 8 d after ALPPS-1. A transcystic stent was placed during ALPPS-1 and remained opened duringthe interval phase, in order to avoid biliary complications. Postoperative liver failure was defined using the 50-50 criteria. Postoperative complications were assessed according to the Dindo-Clavien Classification.RESULTS From January 2014 to December 2015, 7 patients underwent a rescue ALPPS procedure. Median FLR before PVE, ALPPS-1 and ALPPS-2 were respectively 263 cc(221-380), 450 cc(372-506), and 660 cc(575-776). Median FLR/BWR before PVE, ALPPS-1 and ALPPS-2 were respectively 0.4%(0.3-0.5), 0.6%(0.5-0.8), and 1%(0.8-1.2). Median volume growth of FLR was 69%(18-92) after PVE, and 45%(36-82) after ALPPS-1. The combination of PVE and ALPPS induced a growth of median initial FLR of +408 cc(254-513), leading to an increase of +149%(68-199). After ALPPS-2, 4 patients had stage Ⅰ-Ⅱ complications. Three patients had more severe complications(one stage Ⅲ, one stage Ⅳ and one death due to bowel perforation). Two patients suffered from postoperative liver failure according to the 50/50 criteria. None of our patients developed any biliary complication during the ALPPS procedure.CONCLUSION Rescue ALPPS may be an alternative after unsuccessful PVE and could allow previously unresectable patients to reach surgery. Biliary drainage seems to reduce biliary complications.Charlotte Maulat Antoine Philis Bérénice Charriere Fatima-Zohra Mokrane Rosine Guimbaud Philippe Otal Bertrand Suc Fabrice Muscari 2017World Journal of Clinical Oncology2017,8,4:7
2Early plasmapheresis and rituximab for acute humoral rejection after ABO-compatible liver transplantation显示文摘Acute humoral rejection (AHR) is uncommon after ABO-compatible liver transplantation. Herein, we report two cases of AHR treated with plasmapheresis and rituximab in two ABO-compatible liver-transplant patients with preformed anti-human leukocyte antigen donor-specif ic antibodies. Patient 1 experienced a biopsy-proven AHR at day 10 post-transplant. She was treated by steroid pulses, and OKT3. Because of persisting signs of biopsy-proven AHR at day 26, she was treated by plasmapheresis and rituximab. Liver enzyme levels did not improve, and she died on day 41. Patient 2 experienced a biopsy-proven AHR on day 10 post-transplant. She was treated by steroid pulses, plasmapheresis, and rituximab. Liver enzymes returned to within normal range 18 d after diagnosis. Liver biopsies, at 3 and 9 mo post-transplant, showed complete resolution of AHR. We conclude that plasmapheresis should be started as soon as AHR is diagnosed, and be associated with a B-cell depleting agent. Rituximab may be considered as a first-line therapy.Nassim Kamar Laurence Lavayssière Fabrice Muscari Janick Selves Céline Guilbeau-Frugier Isabelle Cardeau Laure Esposito Olivier Cointault Marie Béatrice Nogier Jean Marie Peron Philippe Otal Marylise Fort Lionel Rostaing 2009World Journal of Gastroenterology2009,15,27:6
3Ammonium Ion Adsorption and Settleability Improvement Achieved in a Synthetic Zeolite-Amended Activated Sludge显示文摘Municipal wastewater treatment plants typically exhibit two classic problems: high ammonium concentration in water after conventional biological treatment and,in some cases,poor activated sludge sediment ability.Potential solutions to these problems were investigated by adding a synthetic zeolite obtained from coal fly ash to different steps of activated sludge treatment.The experimental results for ammonium removal fit well with the theoretical adsorption isotherms of the Freundlich model with a maximum adsorption capacity of 13.72 mg·g 1.Utilization of this kind of zeolite to improve activated sludge sediment ability is studied for the first time in this work.It is found that the addition of the zeolite(1 g·L 1) to an activated sludge with settling problems significantly enhances its sediment ability and compact ability.This is confirmed by the sludge volume index(SVI),which was reduced from 163 ml·g 1to 70 ml·g 1,the V60value,which was reduced from 894 ml·L 1to 427 ml·L 1,and the zeta potential(ζ),which was reduced from 19.81 mV to 14.29 mV.The results indicate that the addition of this synthetic zeolite to activated sludge,as an additional waste management practice,has a positive impact on both ammonium removal and sludge settleability.Emilia Otal Luls F. Vilches Yolanda Luna Rodrigo Poblete Juan M. Garcia-Maya Constantino Ferneindez-Pereira 2013Chinese Journal of Chemical Engineering2013,21,9:5
4Predictive factors of histological response of colorectal liver metastases after neoadjuvant chemotherapy显示文摘BACKGROUND Colorectal cancer is the third most common cancer in men and the second most common in women worldwide. Almost a third of the patients has or will develop liver metastases. Neoadjuvant chemotherapy(NAC) has recently become nearly systematic prior to surgery of colorectal livers metastases(CRLMs). The response to NAC is evaluated by radiological imaging according to morphological criteria.More recently, the response to NAC has been evaluated based on histological criteria of the resected specimen. The most often used score is the tumor regression grade(TRG), which considers the necrosis, fibrosis, and number of viable tumor cells.AIM To analyze the predictive factors of the histological response, according to the TRG, on CRLM surgery performed after NAC.METHODSFrom January 2006 to December 2013, 150 patients who had underwent surgery for CRLMs after NAC were included. The patients were separated into two groups based on their histological response, according to Rubbia-Brandt TRG.Based on their TRG, each patient was either assigned to the responder(R) group(TRG 1, 2, and 3) or to the non-responder(NR) group(TRG 4 and 5). All of the histology slides were re-evaluated in a blind manner by the same specialized pathologist. Univariate and multivariate analyses were performed.RESULTS Seventy-four patients were classified as responders and 76 as non-responders.The postoperative mortality rate was 0.7%, with a complication rate of 38%.Multivariate analysis identified five predictive factors of histological response.Three were predictive of non-response: More than seven NAC sessions, the absence of a radiological response after NAC, and a repeat hepatectomy(P <0.005). Two were predictive of a good response: A rectal origin of the primary tumor and a liver-first strategy(P < 0.005). The overall survival was 57% at 3 yr and 36% at 5 yr. The disease-free survival rates were 14% at 3 yr and 11% at 5 yr.The factors contributing to a poor prognosis for disease-free survival were: No histological response after NAC, largest metastasis > 3 cm, more than three preoperative metastases, R1 resection, and the use of a targeted therapy with NAC(P < 0.005).CONCLUSION A non-radiological response and a number of NAC sessions > 7 are the two most pertinent predictive factors of non-histological response(TRG 4 or 5).Chloé Serayssol Charlotte Maulat Florence Breibach Fatima-Zohra Mokrane Janick Selves Rosine Guimbaud Philippe Otal Bertrand Suc Emilie Berard Fabrice Muscari 2019World Journal of Gastrointestinal Oncology2019,11,4:4
5Improved clinical outcome using polytetrafluoroethylene-coated stents for tips: Results of a randomized study显示文摘Christophe Bureau Juan carlos Garcia-Pagan Philippe Otal Gilles Pomier-Layrargues Valérie Chabbert Carlos Cortez Pierre Perreault Jean marie Péron Juan G. Abraldes Louis Bouchard José Ignacio Bilbao Jaume Bosch Hervé Rousseau Jean pierre Vinel 2004Gastroenterology2004,,2:3
6Imaging of retroperitoneal ganglioneuroma显示文摘Philippe Otal Sana Mezghani Sala Hassissene Geert Maleux Daniel Colombier Hervé Rousseau Francis Joffre 2001European Radiology2001,,6:2
7《转喻、语法与交际》评介显示文摘陈香兰 Ruiz de Mendoza Luis Otal Campo 2005现代外语2005,28,4:2
8Macroporous polyester-covered stent in an experimental abdominal aortic aneurysm model显示文摘Soula P Janne d'Othee B Otal P 0,,04:1
9Improved clinical outcome using polytetrafluoroethylene-coated stents for TIPS:results of a randomized study显示文摘Bureau C Garcia-Pngan JC Otal P 2004Gastroenterology2004,126,2:1
10In vitro evaluation of a new rotational thrombectomy device:the Straub Rotarex catheter显示文摘Zana K Otal P Fornet B 2001Cardiovasc Intervent Radiol2001,24,5:1
11The Frattini Subgroup of a Group显示文摘Otal J 2001Margarita Mathematica Spain2001,,:1
12Imaging of retroperitoneal ganglioneuroma显示文摘Otal P Mezghani S Hassissene S 0,,:1
13Thermal annealing of fission tracks in apatite: A quantitative analysis 显示文摘Lasette G M Green P F Duddy I R otal 1987Chemical Geology1987,65,1:1
14Molecular cloning and characterization of Tap,a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis显示文摘Ainsa JA Blokpoel MC J Otal I 1998Journal of Bacteriology1998,180,22:1
15Antiscnsc suppression of proline degradation improves tolerance to freezing and salinity in Arabidopsis thaliana显示文摘Nanjo T Kobayashi M Yoshiha Y otal 1999FEBS Letters1999,461,3:1
16Homocysteine-induced extracellular superoxide dismutase and its epigenetic mechanisms in monocytes 显示文摘Jiang Y Jiang J Xiong J otal 2008J Exp Biol2008,211,:1
17High occlusion rate in experimental transjugular intrahepatie portosystemie shunt ereated with a Dacron-coveted nitinol stent 显示文摘Otal P Rousseau H Vinel JP 1999J Vase Interv Radio/1999,10,:1
18Imaging of retro-peritoneal ganglioneuroma显示文摘Otal P Mezghani S Hassissene S 2001Eur Radiol2001,11,6:1
19Molecular cloning and characterization of Tap,a putative multidrug efflux pump present in mycobacterium fortuitum and mycobacterium tuberculosis显示文摘Ainsa JA Blokpoel MC J Otal I 1998Journal of Bacteriology1998,180,22:1
20Dipyrone interference on several common biochemical tests显示文摘Cascon N Otal C Martinez-Bru C 1993Chem1993,39,6:1
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