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1Application of high silica zeolite ZSM-5 in a hybrid treatment process based on sequential adsorption and ozonation for VOCs elimination显示文摘In this study,a hydrophobic synthetic zeolite,namely ZSM-5 is chosen as an adsorbent/catalyst for toluene removal.Experimental results showed that toluene adsorption onto ZSM-5 was favourable,following a Langmuir adsorption isotherm model.ZSM-5 zeolite was regenerated using gaseous ozone at low temperature.Adsorbed toluene was oxidised,releasing mainly CO_2 and H_2O.Traces of oxidation by-products such as acetic acid and acetaldehyde were formed and remained adsorbed after the oxidativate regeneration with ozone.After four successive cycles of adsorption/ozonation,the adsorption efficiency was not affected(92%-99%).These results showed that volatile organic compound(VOC)removal by adsorption onto ZSM-5 zeolite followed by ozone regeneration could be used as a promising hybrid process for the control of VOC emissions in terms of efficiency.Hicham Zaitan Marie Hélène Manero Héctor Valdés 2016Journal of Environmental Sciences2016,28,3:23
2Uplift, climate and biotic changes at the Eocene-Oligocene transition in south-eastern Tibet显示文摘The uplift history of south-eastern Tibet is crucial to understanding processes driving the tectonic evolution of the Tibetan Plateau and surrounding areas.Underpinning existing palaeoaltimetric studies has been regional mapping based in large part on biostratigraphy that assumes a Neogene modernization of the highly diverse,but threatened,Asian biota.Here,with new radiometric dating and newly collected plant-fossil archives,we quantify the surface height of part of the south-eastern margin of Tibet in the latest Eocene(~34 Ma)to be^3 km and rising,possibly attaining its present elevation(3.9 km)in the early Oligocene.We also find that the Eocene–Oligocene transition in south-eastern Tibet witnessed leaf-size diminution and a floral composition change from sub-tropical/warm temperate to cool temperate,likely reflective of both uplift and secular climate change,and that,by the latest Eocene,floral modernization on Tibet had already taken place,implying modernization was deeply rooted in the Palaeogene.Tao Su Robert A. Spicer Shi-Hu Li He Xu Jian Huang Sarah Sherlock Yong-Jiang Huang Shu-Feng Li Li Wang Lin-Bo Jia Wei-Yu-Dong Deng Jia Liu Cheng-Long Deng Shi-Tao Zhang Paul J. Valdes Zhe-Kun Zhou 2019National Science Review2019,6,3:16
3近红外漫反射光谱法(NIRS)分析稻草纤维及硅化物组成显示文摘水稻稻草硅质化是影响稻谷生产与稻草营养品质的主要因素之一 ,对水稻稻草硅化特点的化学分析费时、耗资、准确度较低。利用近红外漫反射光谱法 (NIRS)具有分析速度快、精度高、结果稳定的优点。对同年采自福建省不同种植地、不同季节、不同品种的稻草及稻叶、叶鞘、茎秆共 92份样品进行半纤维素、纤维素、木质素、可溶及不可溶性硅化物成分的近红外光谱分析。研究利用改进最小偏差 (改进最小二乘法回归技术 )回归法 (ModifiedPLS)进行定标建模 ,并进行交叉验证 (cross validation) ,探讨了用近红外漫反射光谱技术建立稻草纤维及硅化物组成快速预测模型的可行性 ,以及影响NIRS技术在建模应用中的主要因素。沈恒胜 陈君琛 种藏文 赵武善 倪德斌 汤葆莎 Valdes E.V. 2003中国农业科学2003,36,9:14
4FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC显示文摘Over recent years,[18F]-fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography(FDG-PET/CT)has proven its role as a staging modality in patients with non-small cell lung cancer(NSCLC).The purpose of this review was to present the evidence to use FDG-PET/CT for response evaluation in patients with NSCLC,treated with epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKI).All published articles from 1November 2003 to 1 November 2013 reporting on 18FFDG-PET response evaluation during EGFR-TKI treatment in patients with NSCLC were collected.In total 7studies,including data of 210 patients were eligible for analyses.Our report shows that FDG-PET/CT responseduring EGFR-TKI therapy has potential in targeted treatment for NSCLC.FDG-PET/CT response is associated with clinical and radiologic response and with survival.Furthermore FDG-PET/CT response monitoring can be performed as early as 1-2 wk after initiation of EGFR-TKI treatment.Patients with substantial decrease of metabolic activity during EGFR-TKI treatment will probably benefit from continued treatment.If metabolic response does not occur within the first weeks of EGFR-TKI treatment,patients may be spared(further)unnecessary toxicity of ineffective treatment.Refining FDG-PET response criteria may help the clinician to decide on continuation or discontinuation of targeted treatment.Matthijs H van Gool Tjeerd S Aukema Koen J Hartemink Renato A Valdés Olmos Houke M Klomp Harm van Tinteren 2014World Journal of Radiology2014,6,7:8
5大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini 2021英国医学杂志中文版2021,24,8:7
6Adherence to immunosuppressor medication in renal transplanted patients显示文摘Non-adherence is a priority public health concern. Non-adherence means not taking medications, missing medications, taking too much, not taking enough, wrongtiming, wrong dose and/or wrong pill, but may also refer to missing appointments, not booking appointments, not doing blood work, not returning calls and/or refusal to follow the treatment regimen. In renal transplantation, adherence to immunosuppressive medication is a fundamental requisite in order to preserve graft function, since non-adherence is one of the main causes for late acute rejection, incomplete recovery after rejection treatment, chronic graft dysfunction, graft loss, and death. Transplantation failure due to treatment nonadherence is economically, socially, ethically and morally unjustifiable. This is a very prevalent issue: in some studies, its incidence is as high as 70% of patients. The self-reported nonadherence levels found in certain studies, including those performed immediately after transplantation show the need for early and continued intervention after kidney transplantation in order to maximise adherence and consequently clinical outcomes. There is not a single method to assess non adherence, thus combining several measures increases diagnostic accuracy. Electronic monitoring with a microdevice that records each time a pill bottle is opened is considered the 'gold standard' for measuring adherence, but selfreport at a confidential interview was the best measure of adherence. Thus non-adherence risk can be effectively assessed using clinically available assessment tools. Medication Adherence Scale, Brief Medical Questionnaire, Immunosuppressant Therapy Adherence Scale, Immunosuppressant Therapy Barrier Scale, Long-Term Medication Behavior Self-Efficacy Scale and Simplified Medication Adherence Questionnaire are some of the self-reported questionnaires. There are multiple factors associated with non-adherence in immunosuppressant therapy: Younger patients(adolescent, especially), poor health coverage, poor social support, unmarried, no family, non-Caucasian, immigrant, lower income, lower socioeconomic class, greater parental distress and lower family cohesion; complex medical regimens, higher number of drugs, longer time after transplant, toxicity, side effects, poor tolerance to medication, higher number of physicians involved, poor provider-patient rapport; psychological(dependency, high levels of anxiety and hostility, poorer behavioral functioning and greater distress in children) and psychiatric(depression) illnesses, low self-efficacy with medicine intake, perception of immunosuppressive therapy as not been necessary to preserve kidney function, forgetfulness, rebelliousness, poor perception of health, poor satisfaction, low Health-related quality of life, addictions, lack of coping strategies and avoidance behavior; patient morbidity: comorbidity, receiving a transplant from a live donor, retransplantation, and noninsulin-dependent diabetes. The most frequent strategies to promote medication-taking must focus on modifiable risk factors. Reasons for non-adherence are complex and diverse and any successful intervention aimed at improving adherence must be multidimensional. Although effective intervention strategies are needed to improve immunosuppressant therapy adherence, few intervention studies have been conducted in the adult renal transplant population. In this study, we perform an exhaustive review of the different strategies reported in the literature. A number of key reasons for non-adherence are also provided.Francisco Ortega Carmen Díaz-Corte Covadonga Valdés 2015World Journal of Clinical Urology2015,4,1:5
7Transcriptional Regulation and Signaling in Phosphorus Starvation: What About Legumes?显示文摘The availability of soil phosphorus (P), an essential element, is one of the most important requirements for plant growth and crop production. The morphological and physiological adaptations evolved by plants to cope with P starvation have been well characterized. Several P deficiency plant responses are regulated at the transcriptional level. Microarray analysis has generated valuable information on global gene expression in Arabidopsis thaliana grown under P-stress. Despite the identification of P responsive genes, little is known about the regulation of gene expression changes. Four transcription factors, PHR1, WRKY75, ZAT6 and BHLH32, involved in P starvation signaling have been characterized in Arabidopsis, and signaling pathways are deciphered. This review analyzes the current knowledge of transcriptional regulation of P starvation responses in Arabidopsis vis-a`-vis legumes such as lupine, common bean and Medicago truncatula. The knowledge on regulatory and signaling mechanisms involved in P acquisition and use in legumes will be useful for improvement of these crops, which account for a large proportion of the world's crop production, providing good nutritional quality feed and food.Oswaldo Valds-López Georgina Hernndez 2008Journal of Integrative Plant Biology2008,50,10:4
8Specific and cross-reactive immune response against Mycobacterium tuberculosis antigens in mice immunized with proteoliposomes from Mycobacterium bovis BCG显示文摘Objective: To characterize the immunogenicity and the induction of cross-reactive responses against Mycobacterium tuberculosis(M. tuberculosis) of a proteoliposome(PL)from Mycobacterium bovis Bacillus Calmette–Guerin(BCG) with and without alum hydroxide(AL) as adjuvant(PLBCG-AL and PLBCG, respectively) in BALB/c mice.Methods: BALB/c mice were inoculated with phosphate buffer solution, BCG, PLBCG and PLBCG-AL. The humoral immunogenicity was determined by ELISA [immunoglobulin G(Ig G), Ig G1 and Ig G2a] and the cellular immunogenicity was evaluated in vivo by delayed type hypersensitivity. The humoral cross-reactive response against M. tuberculosis was determined by Western blot.Results: Sera from animals immunized with PLBCG-AL and PLBCG showed significant increase in specific total Ig G and Ig G1 antibodies and the presence of cross-reactive antibodies against M. tuberculosis antigens, which were more intense with the use of alum as adjuvant. Mice immunized with PLBCG and PLBCG-AL also showed a specific cellular response in vivo.Conclusions: The cellular and humoral immunogenicity of PLBCG and the capacity to induce cross-reactive responses against M. tuberculosis is in agreement with the protective capacity previously demonstrated by this vaccine candidate and supports the continuation of its evaluation in further stages.Nadine Alvarez DaymíSerpa Ramlah Kadir Yanely Tirado Reinier Borrero Sonsire Fernández Rubén Cabrera Yolanda Valdes Caridad Zayas Reinaldo Acevedo Luis Izquierdo María Elena Sarmiento Mohd-Nor Norazmi JoséLuis Pérez Armando Acosta 2017Asian Pacific Journal of Tropical Biomedicine2017,7,3:3
9Bikunin (Urinary Trypsin Inhibitor): Structure, Biological Relevance, And Measurement显示文摘Michael J. Pugia Roland Valdes Saeed A. Jortani 2007Advances in Clinical Chemistry2007,,:3
10Mapping aboveground biomass by integrating geospatial and forest inventory data through a k-nearest neighbor strategy in North Central Mexico显示文摘As climate change negotiations progress,monitoring biomass and carbon stocks is becoming an important part of the current forest research.Therefore,national governments are interested in developing forest-monitoring strategies using geospatial technology.Among statistical methods for mapping biomass,there is a nonparametric approach called k-nearest neighbor(kNN).We compared four variations of distance metrics of the kNN for the spatially-explicit estimation of aboveground biomass in a portion of the Mexican north border of the intertropical zone.Satellite derived,climatic,and topographic predictor variables were combined with the Mexican National Forest Inventory(NFI)data to accomplish the purpose.Performance of distance metrics applied into the kNN algorithm was evaluated using a cross validation leave-one-out technique.The results indicate that the Most Similar Neighbor(MSN)approach maximizes the correlation between predictor and response variables(r=0.9).Our results are in agreement with those reported in the literature.These findings confirm the predictive potential of the MSN approach for mapping forest variables at pixel level under the policy of Reducing Emission from Deforestation and Forest Degradation(REDD+).Carlos A AGUIRRE-SALADO Eduardo J TREVIO-GARZA Oscar A AGUIRRE-CALDERóN Javier JIMNEZ-PREZ Marco A GONZLEZ-TAGLE José R VALDZ-LAZALDE Guillermo SNCHEZ-DíAZ Reija HAAPANEN Alejandro I AGUIRRE-SALADO Liliana MIRANDA-ARAGóN 2014Journal of Arid Land2014,6,1:3
11Tapering-induced enhancement of light extraction efficiency of nanowire deep ultraviolet LED by theoretical simulations显示文摘A nanowire(NW) structure provides an alternative scheme for deep ultraviolet light emitting diodes(DUV-LEDs)that promises high material quality and better light extraction efficiency(LEE). In this report, we investigate the influence of the tapering angle of closely packed Al Ga N NWs, which is found to exist naturally in molecular beam epitaxy(MBE) grown NW structures, on the LEE of NW DUV-LEDs. It is observed that, by having a small tapering angle, the vertical extraction is greatly enhanced for both transverse magnetic(TM) and transverse electric(TE) polarizations. Most notably, the vertical extraction of TM emission increased from 4.8% to 24.3%,which makes the LEE reasonably large to achieve high-performance DUV-LEDs. This is because the breaking of symmetry in the vertical direction changes the propagation of the light significantly to allow more coupling into radiation modes. Finally, we introduce errors to the NW positions to show the advantages of the tapered NW structures can be projected to random closely packed NW arrays. The results obtained in this paper can provide guidelines for designing efficient NW DUV-LEDs.RONGHUI LIN SERGIO VALDES GALAN HAIDING SUN YANGRUI HU MOHD SHARIZAL ALIAS BILAL JANJUA TIEN KHEE NG BOON S.OOI XIAOHANG LI 2018Photonics Research2018,6,5:3
12Prediction of Fiber Composition and Silicificationfor Rice Straw with Near Infrared ReflectanceSpectroscopy (NIRS) Technique显示文摘The silicification of rice straw is a factor that affects the grain production and straw nutritive quality. The procedure of chemical analysis for silicon in straw is, however, time and labor consuming, and slightly poor in accuracy. The study has attempted to apply near infrared reflectance spectroscopy (NIRS)technique as an advanced alternative to predict the fiber composition and silicification in rice straw. Ninetytwo samples from different seasons and varieties were collected over the Fujian Province. Their chemical analyses were carried on the aspects of hemicellulose, cellulose, lignin, extractable and non-extractable silicon,and the results were used as a database for NIRS analyses. The prediction model was developed through modified partial least square regression (MPLS) for a calibration program. The factors that may affect the calibration, cross-validation and the prediction for the application of NIRS on rice straw were also discussed.Valdes E V 2002Agricultural Sciences in China2002,1,10:2
13Selective uptake of major and trace elements in Erica andevalensis,an endemic species to extreme habitats in the Iberian Pyrite Belt显示文摘To assess the ecophysiological traits and the phytoremediation potential of the endemic heather Erica andevalensis,we determined the concentrations of major and trace elements in different plant parts and in rizosphere soils from Riotinto mining district (Huelva,Spain).The results showed that E.andevalensis may grow on substrates with very high As,Cu,Fe and Pb concentrations (up to 4114,1050,71900 and 15614 μg/g dry weight,respectively),very low availability of macro-and micronutrients and with pH values ranging from 3.3 to 4.9.In these harsh edaphic conditions E.andevalensis selectively absorbed and translocated essential nutrients and excludes potentially phytotoxic elements,which were accumulated in the root epidermis.The concentrations of major and trace elements in E.andevalensis aerial parts from the Riotinto mining district were in the normal range for plants;likewise other Erica species it accumulated Mn and only in a very polluted site we measured leaf concentrations of As and Pb within the excessive or toxic limits for plants.Differently from previous studies,which emphasized the soil pH and bioavailability of phytotoxic elements as the main stress factors,this study showed that in the Riotinto region,E.andevalensis can tolerate wide range of pH and toxic element concentrations;the harshest environments colonized by monospecific patches of this species were characterized above all by very low availability of nutrients.The extraordinary capability to adapt to these extreme habitats made E.andevalensis a priority species to promote the phytostabilization and the development of a self-sustaining vegetative cover on Riotinto mine tailings.Fabrizio Monaci Eduardo O.Leidi Maria Dolores Mingorance Benito Valdés Sabina Rossini Oliva Roberto Bargagli 2011Journal of Environmental Sciences2011,23,3:2
14Comparison between type-2 and type-1 myocardial infarction:clinical features, treatment strategies and outcomes显示文摘ObjectiveTo 与尖锐心肌的梗塞(AMI ).MethodsWe 包括了的 type-2 对 type-1 在病人在发生,临床的特征,当前的治疗策略和结果估计差别有 type-1 或 type-2 AMI 的诊断的 824 个连续病人。在索引住院期间,临床的特征和治疗策略详细被收集。在 1 年的后续,死亡,击,流血的非致命的心肌的梗塞和专业是 recorded.ResultsType-1 AMI 在 707 是在场的(86%) 盒子当(14%) 117 作为 type-2 被分类时。有 type-2 AMI 的病人更经常是象糖尿病那样的女、有的更高的合作病态,以前的非圣片断举起急性冠的症候群,损害肾的功能,贫血症, atrial 纤维性颤动和恶意。然而,保存了左室的喷射部分,正常冠的动脉是经常看见的更多,侵略治疗是不太普通的,并且反血小板药, statins 和 beta-blockers 是在有 type-2 AMI 的病人规定的更少。在 1 年的后续, type-2 AMI 与更高粗略的死亡风险被联系(HR:1.75, 95% CI:1.14-2.68;P = 0.001 ) ,但是这个协会没在 multivariable 调整以后仍然保持重要(P = 0.785 ) 。而且,我们没发现 type-2 AMI 与另外的临床的 outcomes.ConclusionsIn 被联系这张真实人口与 type-1 相比, type-2 AMI 是主要女人们并且有更多的合作病态。侵略治疗策略和 cardioprotective 药是在 type-2 使用的更少,当 1 年的临床的结果是类似的时。Angel Lopez-Cuenca Miriam Gomez-Molina Pedro J Flores-Blanco Marianela Sanchez-Martinez Andrea Garcia-Narbon Ignacio De Las Heras-Gomez Maria J Sainchez-Galian Esther Guerrero-Perez Mariano Valdes Sergio Manzano-Femandez 2016Journal of Geriatric Cardiology2016,13,1:2
15Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation显示文摘Konstantinos E. Hatzistergos Henry Quevedo Behzad N. Oskouei Qinghua Hu Gary S. Feigenbaum Irene S. Margitich Ramesh Mazhari Andrew J. Boyle Juan P. Zambrano Jose E. Rodriguez Raul Dulce Pradip M. Pattany David Valdes Concepcion Revilla Alan W. Heldman Ia 2010Circulation Research2010,,7:2
16Regulated Deficit Irrigation based upon optimum water status improves phenolic composition in Monastrell grapes and wines显示文摘Pascual Romero Rocío Gil-Mu?oz Francisco M. del Amor Esperanza Valdés Jose Ignacio Fernández Adrián Martinez-Cutillas 2013Agricultural Water Management2013,,:2
17ECG after near-drowning mimicking acute coronary syndrome with left main coronary artery involvement显示文摘We present the case of a 74-year-old man with diabetes and hypertension who had to be rescued owing to a near-drowning syndrome at sea.When he was rescued,he complained of dyspnea and chest pain.An electrocardiogram(ECG)suggested acute coronary syndrome(ACS)affecting the left main coronary artery.Therefore,he was referred to our hospital for urgent coronary angiography.Alfredo Vidal García Javier Lacunza Ruiz José María Lpez Ayala Mariano Valdés 2013World Journal of Emergency Medicine2013,4,1:2
18Anatomy and physiology of lymphatic drainage of the breast from the perspective of sentinel node biopsy 显示文摘Tanis PJ Nieweg OE Valdes Olmos RA 2001J Am Coll Surg2001,192,3:1
19Mechanism and Kinetics of Strain Induced Precipitation of Nb (C, N) in Austenite显示文摘Dutta B Valdes E Sellars C M 1992Acta Metallurgica1992,40,4:1
20Soman intoxication alters regional brain muscarinic and GABA receptrs显示文摘Valdes James J Shih Tsuing-ming Whalley Christopher 1985Pesticide Biochem Physi1985,24,3:1
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