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| 1 | Complete laparoscopic resection of the rectum using natural orifice specimen extraction显示文摘AIM: To investigate how complete laparoscopic anterior resection with natural orifice specimen extraction(NOSE), as a novel minimally invasive surgery, compares to conventional laparoscopic surgery.METHODS: Twenty patients who underwent complete laparoscopic anterior resection with NOSE and 50 patients who underwent laparoscopic assisted anterior resection by the conventional method between 2011 and 2012 were studied. Selection for complete laparoscopic anterior resection with NOSE was decided on the basis of tumor size, localization of the tumor, and body mass index. Outcomes related to surgery, including operation time, postoperative wound pain, hospital stay after surgery, the number of totally dissected lymph nodes, postoperative complications(suture failure and wound infection), and anal function, were reviewed retrospectively. Anal function was assessed at 3 and 6 mo after surgery using the Wexner fecal incontinence scoring system.RESULTS: Complete laparoscopic resection with NOSE was performed to completion in all 20 patients. There was no patient emergency that required conversion to conventional laparoscopic surgery or open surgery. The comparison between complete laparoscopic resection with NOSE and conventional laparoscopic surgery showed no significant differences in the maximal diameter of the tumor, number of totally dissected lymph nodes, bleeding volume, mean operation time, time to start of oral ingestion, postoperative hospital stay, and postoperative complications. On the other hand, with regard to pain after epidural anesthesia, the total usage of analgesia in this novel surgical technique was 1.85 ± 1.8 times, whereas it was 5.89 ± 2.86 in conventional laparoscopic surgery(P < 0.001). The postoperative pain period was 1.9 ± 1.9 d in this novel surgical technique, whereas it was 3.43 ± 1.41 d in conventional laparoscopic surgery(P < 0.004). In complete laparoscopic surgery with NOSE, the mean postoperative follow-up period was 20 mo(range: 12-30 mo). Neither local recurrence nor remote metastasis was observed during the follow-up period.CONCLUSION: Complete laparoscopic anterior resection using NOSE does not require any incision and has excellent cosmetic properties, with mitigated postoperative pain. | Masayuki Hisada Kenji Katsumata Tetsuo Ishizaki Masanobu Enomoto Takaaki Matsudo Kazuhiko Kasuya Akihiko Tsuchida | 2014 | World Journal of Gastroenterology2014，20，44： | 45 |
| 2 | Surgical anatomy of innervation of the gallbladder in humans and Suncus murinus with special reference to morphological understanding of gallstone formation after gastrectomy显示文摘瞄准:澄清人的胆囊的神经分布,与在胃切除术以后的胆石形成的词法理解的特殊参考。方法:肝,胆囊和包围结构在乙醇沉浸于茜素红 S 的 10 mg/L 答案在死尸染色周围神经(n = 10 ) 。在区域的神经分布完全在一台双目显微镜下面被把。同样,在 10 Suncus murinus 的一样的区域的神经分布(S。murinus ) 被检验采用整个山免疫组织化学。结果:胆囊的神经分布通过二条线路主要发生了。一个人从前面的肝的丛,神经分布沿着膀胱的动脉和管发生了。总是,这条线路通过了肝十二指肠系带。另外的线路从以后的肝的丛,神经分布沿着膀胱的管 vent 集合发生了。这条线路也通过了肝十二指肠系带欧洲粪金龟子突围。类似的结果在 S 被获得。murinus。结论:从经由膀胱的动脉或管的前面的肝的丛的线路为保存胆囊神经分布是关键的。淋巴节点解剖可以明确地在胃切除术以后在肝十二指肠系带影响胆石的发生。而且,从经由到胆囊的胆总管和膀胱的管的以后的肝的丛的线路不应该被不顾。丛的保藏可以在胃切除术以后稀释胆石形成的发生。 | Shuang-Qin Yi Tetsuo Ohta Akihiko Tsuchida Hayato Terayama Munekazu Naito Jun Li Heng-Xiao Wang Nozomi Yi Shigenori Tanaka Masahiro Itoh | 2007 | World Journal of Gastroenterology2007，13，14： | 19 |
| 3 | Carcinogenesis and chemoprevention of biliary tract cancer in pancreaticobiliary maljunction显示文摘Pancreaticobiliary maljunction (PBM) is a high risk factor for biliary tract cancer. In PBM, since the pancreatic duct and bile duct converge outside the duodenal wall beyond the influence of the sphincter of Oddi, pancreatic juice and bile are constantly mixed, producing a variety of harmful substances. Because of this, the biliary mucosa is repeatedly damaged and repaired, which causes an acceleration of cell proliferative activity and multiple gene mutations. Histological changes such as hyperplasia, metaplasia, and dysplasia ultimately result in a high incidence of carcinogenesis. In a nationwide survey by the Japanese Study Group on PBM, coexisting biliary tract cancer was detected in 278 of the 1627 registered cases of PBM (17.1%). Of these cases, in those with dilatation of the extrahepatic bile duct, cancer was often detected not only in the gallbladder but also in the bile ducts. More than 90% of cancer cases without dilatation of the extrahepatic bile duct develop in the gallbladder. Standard treatment for PBM is a cholecystectomy and resection of the extrahepatic bile duct. However, cholecystectomy alone is performed at nearly half of institutions in Japan. Conversely, reports of carcinogenesis in the remnant bile duct or pancreas after diversion surgery are steadily increasing. One of the causes for this is believed to be an accumulation of gene mutations which were present before surgery. Anticancer drugs are ineffective in preventing such carcinogenesis following surgery, thus the postoperative administration of chemopreventive agents may be necessary. | Akihiko Tsuchida Takao Itoi | 2010 | World Journal of Gastrointestinal Oncology2010，2，3： | 10 |
| 4 | Endobronchial metastasis from adenocarcinoma of gastric cardia 7 years after potentially curable resection显示文摘Endobronchial metastasis(EBM) is a rare form of metas-tasis from extrapulmonary malignant tumors,although there are few reports of EBM from gastric cancer specifically.We report the case of a 51-year-old woman who had undergone gastrectomy for advanced gastric cancer seven years previously but was diagnosed with a solitary lung tumor by follow-up computed tomography.On diagnosis of primary lung cancer,she underwent pulmonary lobectomy,but immunohistochemical examination confirmed the resected tumor to be an EBM from the gastric cancer.Six months later,she was diagnosed with peritoneal metastases and underwent chemotherapy with gastric cancer regimen.She is still alive at 33 mo after the lobectomy.Generally,the prognosis for EBM is poor although multidisciplinary treatment can lead to long-term survival.Precise diagnosis on the basis of detailed pathological and immunohistochemical evaluation can contribute to deciding the most effective treatment and improving prognosis. | Takaaki Hanyu Tatsuo Kanda Atsushi Matsuki Go Hasegawa Kazuhito Yajima Masanori Tsuchida Shin-ichi Kosugi Makoto Naito Katsuyoshi Hatakeyama | 2010 | World Journal of Gastrointestinal Surgery2010，2，8： | 7 |
| 5 | 常规临床实践中西罗莫司洗脱支架和紫杉醇洗脱支架的早期和晚期冠状动脉支架血栓形成之比较:一项较大规模、由两个机构完成的队列研究的资料 | Daemen J. Wenaweser P. Tsuchida K. et P.W. Serruys 杜媛 | 2007 | 世界核心医学期刊文摘(心脏病学分册)2007，0，8： | 4 |
| 6 | 微导通孔的电镀填孔技术显示文摘本文主介绍了电镀填孔技术,并探讨了DC和PPR电镀填孔技术的优缺点和影响填孔效果的相关因素。 | George Allardyce Mark Lefebvre Hideki Tsuchida Masaru Kusaka Shinjiro Hayashi 张伯兴 | 2004 | 印制电路信息2004，，10： | 4 |
| 7 | Oncological results, functional outcomes and health-related quality-of-life in men who received a radical prostatectomy or external beam radiation therapy for localized prostate cancer: a study on long-term patient outcome with risk stratification显示文摘在激进的前列腺切除术(RP ) 或外部横梁放射治疗(EBRT ) 以后的健康相关的 quality-of-life (HRQOL ) 没在与疾病风险层化的关系与 oncological 结果一起被学习。而且,这些治疗途径的长期的结果没被学习。我们回顾地分析了在收到 RP 的连续病人之间的 oncological 结果(n = 86 ) 并且 EBRT (n = 76 ) 为局部性的前列腺癌症。HRQOL 和功能的结果能在 62 RP (79%) 和 54 EBRT (79%) 被估计在一个 3 年的后续时期上的病人(中部:41 个月) 用医药结果学习,短 Form-36 (SF-36 ) 和加利福尼亚大学洛杉机前列腺癌症索引(UCLA 一种总线标准) 。5 年的生物化学的没有前进的幸存没在 RP 和 EBRT 组之间不同为低风险(74.6% 对 75.0% , P = 0.931 ) 并且中间风险(61.3% 对 71.1% , P = 0.691 ) 病人。为高风险的病人,没有前进的幸存比在 EBRT 组(79.7%) 在 RP 组(45.1%) 是更低的(P = 0.002 ) 。一般 HRQOL 在二个组之间是可比较的。关于功能的结果, RP 组比 EBRT 组在尿功能和不太尿的麻烦和性麻烦上报导了更低的分数(P < 0.001, P < 0.05 并且 P < 0.001,分别地) 。与风险层化,在 RP 组的低风险、中间风险的病人在 EBRT 组比病人报导了更差的尿功能(P < 0.001 为各个) 。在 EBRT 组的高风险的病人的性功能比一样的风险 RP 病人的好(P < 0.001 ) 。生物化学的复发没在任何一个组与 UCLA 一种总线标准分数被联系。在结论,低 -- 可以在长期的后续期间向与 RP 对待的中间风险的病人汇报相对减少的尿功能。病人在治疗以后的 HRQOL 没取决于生物化学的复发。 | Itsuhiro Takizawa Noboru Hara Tsutomu Nishiyama Masaaki Kaneko Tatsuhiko Hoshii Emiko Tsuchida Kota Takahashi | 2009 | Asian Journal of Andrology2009，11，3： | 3 |
| 8 | Body mass index correlated with forced expiratory volume in 1 second/forced vital capacity in a population with a relatively low prevalence of obesity显示文摘背景肥胖是在世界上的最普通的新陈代谢的疾病。然而,在肥胖之间的关系和肺功能充分没被理解。尽管几纵的研究证明了那在身体增加,重量能在肺的功能导致减小,这是否并且是否高是有日本人口的盒子身体团索引( BMI )地位独自代表现在的学习的 unclear.The 目的是在日本病人的呼吸量测定法在一般诊所测量的肺功能上估计 BMI 的效果的妨碍的肺机能障碍遗体的一个适当预言者。我们屏蔽请教了一般 clinics.Methods 题目的病人上的测量 BMI 和执行呼吸量测定法包括了 1231 个病人 40 岁(吝啬的年龄(65. | Susumu Fukahori Hiroto Matsuse Nobom Takamura Tomoko Tsuchida Tetsuya Kawano Chizu Fukushima Senjyu Hideaki Shigeru Kohno | 2010 | Chinese Medical Journal2010，，20： | 3 |
| 9 | Prognosis of cancer with branch duct type IPMN of the pancreas显示文摘AIM:To examine the coexistence of metachronous and synchronous cancer in branch duct intraductal papillary mucinous neoplasms of the pancreas (IPMN).METHODS: We reviewed the records of 145 patients with branch duct IPMN between January 1991 and April 2008 and assessed the relationship between IPMN and intraor extra-pancreatic carcinoma and the outcome of IPMN.RESULTS: The mean observation period was 55.9 ± 45.3 mo. Among the 145 patients, the frequency of extra-pancreatic cancer was 29.0%. The frequency of gastric cancer, colon cancer, breast cancer, and pan-creatic cancer were 25.5%, 15.7%, 13.7%, and 9.8%, respectively. Twenty (13.8%) of the patients died. The cause of death was extra-pancreatic carcinoma in 40%,pancreatic cancer in 25%, IPMN per se in 20%, and benign disease in 15% of the patients.CONCLUSION: The prognosis for IPMN depends not on the IPMN per se, but on the presence of intraor extra-pancreatic cancer. | Nobuhito Ikeuchi Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Junko Umeda Fuminori Moriyasu Akihiko Tsuchida Kazuhiko Kasuya | 2010 | World Journal of Gastroenterology2010，16，15： | 3 |
| 10 | Clinical importance of colonoscopy in patients with gastric neoplasm undergoing endoscopic submucosal dissection显示文摘AIM To evaluate the usefulness of total colonoscopy(TCS) for patients undergoing gastric endoscopic submucosal dissection(ESD) and to assess risk factors for colorectal neoplasms.METHODS Of the 263 patients who underwent ESD at our department between May 2010 and December 2013, 172 patients undergoing TCS during a one-year period before and after ESD were targeted. After excluding patients with a history of surgery or endoscopic therapy for colorectal neoplasms, 158 patients were analyzed. Of the 868 asymptomatic patients who underwent TCS during the same period because of positive fecal immunochemical test(FIT) results, 158 patients with no history of either surgery or endoscopic therapy for colorectal neoplasms who were matched for age and sex served as the control group for comparison.RESULTS TCS revealed adenoma less than 10 mm in 53 patients(33.6%), advanced adenoma in 17(10.8%), early colorectal cancer in 5(3.2%), and advanced colorectalcancer in 4(2.5%). When the presence or absence of adenoma less than 10 mm, advanced adenoma, and colorectal cancer and the number of adenomas were compared between patients undergoing ESD and FITpositive patients, there were no statistically significant differences in any of the parameters assessed. The patients undergoing ESD appeared to have the same risk of colorectal neoplasms as the FIT-positive patients. Colorectal neoplasms were clearly more common in men than in women(P = 0.031). Advanced adenoma and cancer were significantly more frequent in patients with at least two of the following conditions: hypertension, dyslipidemia, and diabetes mellitus(P = 0.019).CONCLUSION In patients undergoing gastric ESD, TCS appears to be important for detecting synchronous double neoplasms. Advanced adenoma and cancer were more common in patients with at least two of the following conditions: hypertension, dyslipidemia, and diabetes mellitus. Caution is therefore especially warranted in patients with these risk factors. | Chieko Tsuchida Naoto Yoshitake Hitoshi Kino Yoshihito Kaneko Masakazu Nakano Kohei Tsuchida Keiichi Tominaga Takako Sasai Hironori Masuyama Hidetsugu Yamagishi Yasuo Imai Hideyuki Hiraishi | 2017 | World Journal of Gastroenterology2017，23，23： | 3 |
| 11 | Inhibition of IRF3-dependent antiviral responses by cellular and viral proteins显示文摘 | Tetsuo Tsuchida Faro Kawai Shizuo Akira | 2009 | Cell Research2009，19，1： | 3 |
| 12 | The leaf extract of Mallotus japonicus and its major active constituent, rutin,suppressed on melanin production in murine B16F1 melanoma显示文摘Objective: To find anti-melanogenesis materials used in whitening cosmetics.Methods: The ethanolic leaf extract of Mallotus japonicus(M. japonicus) having an anti-melanogenesis activity was separated by a sephadex LH-20 chromatography. Each fraction was measured for its tyrosinase inhibitory activity together with its polyphenol content using the Folin–Ciocalteu method. The anti-melanogenesis activity of the active fractions was determined by the melanin content in the murine B16F1 melanoma. The active fractions were put together due to similar constituents, and then separated by high performance liquid chromatography using a C-18 ODS column. The major antimelanogenesis compound was identified using1 H and13C-NMR and liquid chromatography-mass spectrometry.Results: The ethanolic leaf extract of M. japonicus showed an anti-tyrosinase activity with a high polyphenol content, resulting in suppression of melanin production in the B16F1 melanoma. The extract was separated and the active compound was identical as rutin based on the1 H,13C-NMR and liquid chromatography-mass spectrometry analysis data. In addition, the rutin treatment with cells reduced the melanin content in a concentration dependent manner without any cell toxicity. The leaf extract of M. japonicus containing rutin would be useful in whitening cosmetics for protection from UV-light exposure to be limiting the accumulation of melanin in skin.Conclusions: The leaf extract of M. japonicus and/or rutin isolated from the extract as a key whitening agent would be useful as a whitening cosmetic material for protecting against disorder skin due to melanin accumulation. | Junsei Taira Eito Tsuchida Masatsugu Uehara Natsuko Ohhama Wakana Ohmine Takayuki Ogi | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，10： | 2 |
| 13 | Digital transmission of high bit rate signals using 16DAPSK-OFDM Modulation scheme显示文摘 | Moriyama S Tsuchida K Sasaki M | 1998 | IEEE Transmission on Broadcasting1998，44，1： | 2 |
| 14 | On compression characteristics of Ariake clays显示文摘 | Hong Z Tsuchida T | 1999 | Canadian Geotechnical Journal1999，36，5： | 2 |
| 15 | Consequences of coinfection with protective symbionts on the host phenotype and symbiont titres in the pea aphid system显示文摘在微生物和昆虫之间的共生协会是普遍的,并且几个共生者分享一样的主人个人,是经常的。因此,相互作用能发生在这些共生者之间,影响他们在有它的显型上的后果的主人以内的各自的丰富。这里,我们在豌豆蚜虫调查多重感染的效果, Acyrthosiphon pisum,它是主人一应尽并且几个容许的共生者。特别地,我们与 2 个保护的共生者学习 coinfection 的影响:Hamiltonella defensa,它对 parasitoids 授与保护,和 Rickettsiella viridis。各自的许多上的 Hamiltonella-Rickettsiella coinfection 的效果共生者,主人健康和敌人保护的功效被学习。在 2 个保护的共生者之间的不均匀的相互作用被发现了:什么时候他们 coinfect 一样的蚜虫个人,当 Hamiltonella 感染否定地影响调停 Rickettsiella 的保护的显型然而并非它的丰富时, Rickettsiella 感染在主人然而并非调停 Hamiltonella 的保护的显型以内影响了 Hamiltonella 丰富。怀有 2 个保护的共生者也减少了主人个人的幸存和肥沃。总的来说,这个工作在是可能的在自然产地影响共生协会的维护的共生者丰富和主人特点上加亮多重感染的效果。 | Melanie Leclair Sarah Polin Thibaut Jousseaume Jean-Christophe Simon Akiko Sugio Stephanie Morliere Takema Fukatsu Tsutomu Tsuchida Yannick Outreman | 2017 | Insect Science2017，24，5： | 2 |
| 16 | Clinical characterization of gastric lesions initially diagnosed as low‐grade adenomas on forceps biopsy显示文摘 | Akiyoshi Kasuga Yorimasa Yamamoto Junko Fujisaki Kazuhisa Okada Masami Omae Akiyoshi Ishiyama Toshiaki Hirasawa Akiko Chino Tomohiro Tsuchida Masahiro Igarashi Etsuo Hoshino Noriko Yamamoto Minoru Kawaguchi Rikiya Fujita | 2012 | Digestive Endoscopy2012，，5： | 2 |
| 17 | Long-term outcomes of endoscopic submucosal dissection for undifferentiated-type early gastric cancer显示文摘 | K. Okada J. Fujisaki T. Yoshida H. Ishikawa T. Suganuma A. Kasuga M. Omae M. Kubota A. Ishiyama T. Hirasawa A. Chino M. Inamori Y. Yamamoto N. Yamamoto T. Tsuchida Y. Tamegai A. Nakajima E. Hoshino M. Igarashi | 2012 | Endoscopy2012，，02： | 2 |
| 18 | Endoscopic ultrasonography-guided biliary drainage显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu Akihiko Tsuchida | 2010 | Journal of Hepato-Biliary-Pancreatic Sciences2010，，5： | 2 |
| 19 | Biomarkers of Brain Injury in Neonatal Encephalopathy Treated with Hypothermia显示文摘 | An N. Massaro Taeun Chang Nadja Kadom Tammy Tsuchida Joseph Scafidi Penny Glass Robert McCarter Stephen Baumgart Gilbert Vezina Karin B. Nelson | 2012 | The Journal of Pediatrics2012，，3： | 2 |
| 20 | Influence of paroxysmal atrial fibrillation attack on brain nalriurelic peptide secretion显示文摘 | Tsuchida K Tanabe K | 2004 | J Cardial2004，44，1： | 1 |
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