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| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | Intracralial Delivery of the Nitric Oxide Donor Diethylenetriamine/nitrie Oxide from a Controlledreleasw Polymer : Toxicity in Cynomolgus Monkeys显示文摘 | Travis S Tierney M D | 2006 | Neurosurgery2006，58，： | 1 |
| 3 | Expression of surfactant associ-ated protein-A and Clara cell 10 kilodahon mRNA in neoplastic and non-neoplastichuman lung tissue as detected by in situ hybridization 显示文摘 | Broers J L Jensen S M Travis W D | 1992 | Lab Invest1992，66，3： | 1 |
| 4 | An official American Thoracic Society/European Respiratory Society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias显示文摘 | Travis W D Costabel U Hansell D M | 2013 | Am J Respir Crit Care Med2013，188，6： | 1 |
| 5 | Differential effect of amino acid on nitrate uptake and reduction systems in barley roots显示文摘 | Aslam M Travis R L Rains D W | 2001 | Plant Science2001，160，： | 1 |
| 6 | Electromagnetic Induction by a Finite Electric Dipole Source Over a 2-D Earth显示文摘 | Unsworth M J Travis B J Chave A D | 1993 | Geophysics1993，58，1： | 1 |
| 7 | A methodology for developing integrated information systems based on ERP package显示文摘 | Stirling M Petty D Travis I | | 0，，05： | 1 |
| 8 | SciAutonics-Auburn engi- neering's low-cost high-speed ATV for the 2005 DARPA grand challenge显示文摘 | Travis W Daily R Bevly D M | 2006 | Journal of Field Robotics2006，23，8： | 1 |
| 9 | Cancer surveillance series:non-Hodgkin's lymphoma incidence by histologic subtype in the United States from 1978 through 1995显示文摘 | Groves F D Liner M S Travis L B | 2000 | J Natl Cancer Inst2000，92，15： | 1 |
| 10 | Electromagnetic induction by a finite electric dipole source o- ver a 2-D earth 显示文摘 | UNSWORTH M J TRAVIS B J CHAVE A D | 1993 | Geophysics1993，58，2： | 1 |
| 11 | Electromagnetic induction by a finite electric dipole source over a 2-D earth显示文摘 | UNSWORTH M J TRAVIS B J CHAVE A D | 1993 | Geophysics1993，58，2： | 1 |
| 12 | Radical change accidentally: The emergence and amplification of small change显示文摘 | Plowman D Baker L T Beck T Kulkami M Solansky S and Travis D | 2007 | Academy of Management Journal2007，50，3： | 1 |
| 13 | SciAutonics - Auburnengineering,s low - cost high - speed ATV for the 2005 DA-PRA grand challenge 显示文摘 | TRAVIS W DAILY R BEVLY D M | 2006 | Journal of Field Robotics2006，23，8： | 1 |
| 14 | Modeling phase functions for dustlike tropospheric aerosols using a shape mixture of randomly oriented polydisperse spheroids 显示文摘 | MISHCHENKO M I TRAVIS L D KAHN R A | 1997 | Journal of Geophysical Research(S0148-0227)1997，102，16： | 1 |
| 15 | Differential effect of amino acid on nitrate uptake and reduction systems in barley roots显示文摘 | Aslam M Travis R L Rains D W | 2001 | Plant Science2001，160，： | 1 |
| 16 | Primary myoepithelial carcinoma of the lung: a rare entity treated with parenchymal sparing resection显示文摘 | Sarkaria IS DeLair D Travis W D Flores R M | 2011 | J Cardiothorac Surg2011，6，： | 1 |
| 17 | IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4 + T Cells显示文摘 | Stefan Pflanz Jackie C Timans Jeanne Cheung Rency Rosales Holger Kanzler Jonathan Gilbert Linda Hibbert Tatyana Churakova Marilyn Travis Elena Vaisberg Wendy M Blumenschein Jeanine D Mattson Janet L Wagner Wayne To Sandra Zurawski Terrill K McClanahan Dan | 2002 | Immunity2002，，6： | 1 |
| 18 | Differential effect of amino acids on nitrate uptake and reducation systems in barley roots 显示文摘 | ASLAM M TRAVIS R L RAINS D W | 2001 | Plant Science2001，160，2： | 1 |
| 19 | Contrails reduce daily temperature range显示文摘 | Travis D J Carleton A M Lauritsen R G | 2002 | Nature2002，418，6898： | 1 |
| 20 | Diferential effect of ami noacids on nitrate uptake and reduction systems in barley roots 显示文摘 | Aslam M Travis R L Rains D W | 2001 | Plant Science2001，160，2： | 1 |
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