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| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Current management显示文摘 | A. Dignass G. Van Assche J.O. Lindsay M. Lémann J. S?derholm J.F. Colombel S. Danese A. D’Hoore M. Gassull F. Gomollón D.W. Hommes P. Michetti C. O’Morain T. ?resland A. Windsor E.F. Stange S.P.L. Travis | 2010 | Journal of Crohn’s and Colitis2010，，1： | 2 |
| 3 | Intracralial Delivery of the Nitric Oxide Donor Diethylenetriamine/nitrie Oxide from a Controlledreleasw Polymer : Toxicity in Cynomolgus Monkeys显示文摘 | Travis S Tierney M D | 2006 | Neurosurgery2006，58，： | 1 |
| 4 | Overcoming health-systems constraints to achieve the Millennium Development Goals 显示文摘 | Travis P Hennett S Haines A | 2004 | Lancet2004，364，： | 1 |
| 5 | Which 5-ASA? 显示文摘 | Travis S | 2002 | Gut2002，51，： | 1 |
| 6 | Intestinal permeability: functional assessment and significance 显示文摘 | Travis S Menzies I | 1992 | Clinical Science1992，82，： | 1 |
| 7 | Expression of surfactant associ-ated protein-A and Clara cell 10 kilodahon mRNA in neoplastic and non-neoplastichuman lung tissue as detected by in situ hybridization 显示文摘 | Broers J L Jensen S M Travis W D | 1992 | Lab Invest1992，66，3： | 1 |
| 8 | Conventional medical management of inflammatory bowel disease显示文摘 | Burger D Travis S | | 0，，06： | 1 |
| 9 | Evidence that monoclonal antibodies directed against the integrin β subunit plexin/ semaphorin/integrin domain stimulate function by inducing receptor extension显示文摘 | Mould A P Travis M A Barton S J | 2005 | J Biol Chem2005，280，6： | 1 |
| 10 | Interactive effects of temperature and salinity on otolithchemistry:challenges for determining environmental histories of fish显示文摘 | Elsdon Travis S Gillanders Bronwyn M | 2002 | Canadian Journal of Fish-eries and Aquatic Sciences2002，59，： | 1 |
| 11 | Lung cancer 显示文摘 | Travis W D Travis L B Devesa S S | 1995 | Cancer1995，75，1： | 1 |
| 12 | Global Stability of a Biological Model with Time Delay 显示文摘 | Lenhart S M Travis C C | 1986 | Proc Amer Math Soc1986，96，1： | 1 |
| 13 | Mutations in the human retinal degeneration slow gene in autosomal dominant retinitis pigmentosa显示文摘 | Hahn LB Mukai S Travis GH Berson EL Dryja TP | 1991 | Nature1991，354，6353： | 1 |
| 14 | Intestinal permeability:functional assessment adn signifficance显示文摘 | Travis S Menzies I | 1992 | Clinical Science1992，82，： | 1 |
| 15 | Ele- vated CO2 increases productivity and invasive species success in an arid ecosystem显示文摘 | STANLEY D S Travis E H Stephen F Z | 2000 | Nature2000，408，2： | 1 |
| 16 | Estimation of the spatial distribu- tion of target cells for radiation pneumonitis in mouse lung 显示文摘 | Tucker S L Liao Z X Travis E L | 1997 | Int J Radiat Oncol Biol Phys1997，38，5： | 1 |
| 17 | Complete temporal characterization of a single photon显示文摘Precise information about the temporal mode of optical states is crucial for optimizing their interaction efficiency between themselves and/or with matter in various quantum communication devices.Here we propose and experimentally demonstrate a method of determining both the real and imaginary components of a single photon’s temporal density matrix by measuring the autocorrelation function of the photocurrent from a balanced homodyne detector at multiple local oscillator frequencies.We test our method on single photons heralded from biphotons generated via four-wave mixing in an atomic vapor and obtain excellent agreement with theoretical predictions for several settings. | Zhongzhong Qin Adarsh S Prasad Travis Brannan Andrew MacRae A Lezama AI Lvovsky | 2015 | Light(Science & Applications)2015，4，1： | 1 |
| 18 | Microsatellite DNA loci for genetic studies of Cranes 显示文摘 | TRAVIS C G RYAN S O WOLFGANG S | 1997 | Proc North Am Crane Workshop1997，7，： | 1 |
| 19 | A high-density soybean genetic map based on AFLP markers 显示文摘 | Keim P Schupp J M Travis S E | 1997 | Crop Sci1997，37，： | 1 |
| 20 | Lung cancer 显示文摘 | Travis W D Travis L B Devesa S S | 1995 | Cancer1995，75，1： | 1 |
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