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| 1 | High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease显示文摘AIM:To examine the detection rate of viable Mycobacterium avium subspecies paratuberculosis(MAP) in patients with inflammatory bowel disease [Crohn's disease(CD) and ulcerative colitis(UC)].METHODS:Thirty patients with CD(15 with at least one NOD2/CARD15 mutation),29 with UC,and 10 with no inflammatory bowel disease(IBD).were tested for MAP by polymerase chain reaction(specific IS900 fragment) and blood culture.RESULTS:MAP DNA was detected in all original blood samples and 8-wk blood cultures(CD,UC and non-IBD).Positive MAP DNA status was confirmed by dot blot assays.All 69 cultures were negative by acid-fast Ziehl-Neelsen staining.Viable MAP,in spheroplast form,was isolated from the 18-mo blood cultures of all 30 CD patients,one UC patient,and none of the non-IBD controls.No association was found between positive MAP cultures and use of immunosuppressive drugs or CDassociated single nucleotide polymorphisms.CONCLUSION:MAP is widely present in our area and MAP DNA can be recovered from the blood of CD,UC and non-IBD patients.However,MAP spheroplasts were only found in CD patients. | Juan L Mendoza Amparo San-Pedro Esther Culebras Raquel Cíes Carlos Taxonera Raquel Lana Elena Urcelay Fernando de la Torre Juan J Picazo Manuel Díaz-Rubio | 2010 | World Journal of Gastroenterology2010，16，36： | 5 |
| 2 | Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS):the Brazilian experience 显示文摘 | Torres O J Femandes ES Oliveira CV | 2013 | Arq Bras Cir Dig2013，26，1： | 1 |
| 3 | Mid- and near-infrared spectroscopic assessment of soil compositional parameters and structural indices in two Ferralsols显示文摘 | Beáta E. Madari James B. Reeves Pedro L.O.A. Machado Cleber M. Guimar?es Eleno Torres Gregory W. McCarty | 2006 | Geoderma2006，，1： | 1 |
| 4 | Expression of alternatively spliced fibronectin variants during remodeling in proliferative glomerulonephritis显示文摘 | Barnes JL Torres ES Mitchell RJ | 1995 | Am J Pathol1995，147，5： | 1 |
| 5 | Xylitol dehydrogenase from Candida tropicalis: molecular cloning of the gene and structural analysis of the protein显示文摘 | Luanne Helena Augusto Lima Cristiano Guimar?es do Amaral Pinheiro Lídia Maria Pepe Moraes Sonia Maria Freitas Fernando Araripe Gon?alves Torres | 2006 | Applied Microbiology and Biotechnology2006，，3： | 1 |
| 6 | PCR multiplex for detection of Salmonella Enteritidis, Typhi and Typhimurium and occurrence in poultry meat显示文摘 | Camila Guimar?es de Freitas ?ngela Patrícia Santana Patrícia Helena Caldeira da Silva Vítor Salvador Pic?o Gon?alves Márcia de Aguiar Ferreira Barros Fernando Araripe Gon?alves Torres Luci Sayori Murata Simone Perecmanis | 2010 | International Journal of Food Microbiology2010，，1： | 1 |
| 7 | Deregulation of miR-100, miR-99a and miR-1998 in tissues and plasma coexists with in- creased expression of mTOR kinase ill endometrioid endometrial carcinoma 显示文摘 | Ton'es A Torres K Pesci A | 2012 | BMC Cancer2012，12，： | 1 |
| 8 | Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) : the Brazilian expellence显示文摘 | Torres OJ Fernandes ES Oliveira CV | 2013 | Arq Bras Cir Dig2013，26，1： | 1 |
| 9 | Associating liver par- tition and portal vein ligation for staged hepatectomy(ALPPS):the Brazilian experience显示文摘 | Torres OJ Fernandes ES Oliveira CV | 2013 | Arq Bras Cir Dig2013，26，1： | 1 |
| 10 | Effect of caries infiltration technique and fluoride therapy on the colour masking of white spot lesions显示文摘 | Carlos Rocha Gomes Torres Alessandra Buhler Borges Luciana Marcondes Sarmento Torres Isabela Silva Gomes Rodrigo Sim?es de Oliveira | 2011 | Journal of Dentistry2011，，3： | 1 |
| 11 | In-vitro and in-vivo antitumour activity of physalins B and D from Physalis angulata显示文摘 | Magalhes HI Veras ML Torres MR | 2006 | Pharm Pharmacol2006，58，2： | 1 |
| 12 | Early diagnosis of subependymal giant cell astrocytoma in patients with tuberous sclerosis显示文摘 | Torres OA Roach ES Delgado MR | 1998 | J Child Neurol1998，13，4： | 1 |
| 13 | The accuracy of acetylcholinesterase reaction in rectal suction biopsy in the diagnosis of Hirschsprung's disease显示文摘 | Gugelmin ES Torres LF | 2005 | J Bras Patol Med Lab2005，41，6： | 1 |
| 14 | Corrosion inhibition at galvanized steel cut edges by phosphate pigments显示文摘 | A.M. Sim?es J. Torres R. Picciochi J.C.S. Fernandes | 2009 | Electrochimica Acta2009，，15： | 1 |
| 15 | Neglected tropical diseases risk correlates with poverty and early ecosystem destruction显示文摘Background Neglected tropical diseases affect the most vulnerable populations and cause chronic and debilitating disorders.Socioeconomic vulnerability is a well-known and important determinant of neglected tropical diseases.For example,poverty and sanitation could influence parasite transmission.Nevertheless,the quantitative impact of socioeconomic conditions on disease transmission risk remains poorly explored.Methods This study investigated the role of socioeconomic variables in the predictive capacity of risk models of neglected tropical zoonoses using a decade of epidemiological data(2007–2018)from Brazil.Vector-borne diseases investigated in this study included dengue,malaria,Chagas disease,leishmaniasis,and Brazilian spotted fever,while directly-transmitted zoonotic diseases included schistosomiasis,leptospirosis,and hantaviruses.Environmental and socioeconomic predictors were combined with infectious disease data to build environmental and socioenvironmental sets of ecological niche models and their performances were compared.Results Socioeconomic variables were found to be as important as environmental variables in influencing the estimated likelihood of disease transmission across large spatial scales.The combination of socioeconomic and environmental variables improved overall model accuracy(or predictive power)by 10%on average(P<0.01),reaching a maximum of 18%in the case of dengue fever.Gross domestic product was the most important socioeconomic variable(37%relative variable importance,all individual models exhibited P<0.00),showing a decreasing relationship with disease indicating poverty as a major factor for disease transmission.Loss of natural vegetation cover between 2008 and 2018 was the most important environmental variable(42%relative variable importance,P<0.05)among environmental models,exhibiting a decreasing relationship with disease probability,showing that these diseases are especially prevalent in areas where natural ecosystem destruction is on its initial stages and lower when ecosystem destruction is on more advanced stages.Conclusions Destruction of natural ecosystems coupled with low income explain macro-scale neglected tropical and zoonotic disease probability in Brazil.Addition of socioeconomic variables improves transmission risk forecasts on tandem with environmental variables.Our results highlight that to efficiently address neglected tropical diseases,public health strategies must target both reduction of poverty and cessation of destruction of natural forests and savannas. | Arthur Ramalho Magalhães Cláudia Torres Codeço Jens-Christian Svenning Luis E.Escobar Paige Van de Vuurst Thiago Gonçalves-Souza | 2023 | Infectious Diseases of Poverty2023，12，2： | 0 |
| 16 | Bird habitat preferences drive hemoparasite infection in the Neotropical region显示文摘The role that the environment plays in vector-borne parasite infection is one of the central factors for understanding disease dynamics.We assessed how Neotropical bird foraging strata and habitat preferences determine infection by parasites of the genera Haemoproteus,Plasmodium,Leucocytozoon,and Trypanosoma and filarioids,and tested for phylogenetic signal in these host-parasite associations.We performed extensive searches of the scientific literature and created a database of hemoparasite surveys.We collected data on host body mass,foraging strata,habitat preference,and migratory status,and tested if host ecological traits predict each hemoparasite occurrence and prevalence using a phylogenetic Bayesian framework.Species of Plasmodium tend to infect birds from tropical forests while birds from altitudinal environments are likely to be infected by species of Leucocytozoon.The probability of a bird being infected by filarioid or Trypanosoma is higher in lowland forests.Bird species that occur in anthropic environments and dry habitats of tropical latitudes are more susceptible to infection by species of Haemoproteus.Host foraging strata is also influential and bird species that forage in the mid-high and canopy strata are more prone to infection by species of Haemoproteus and filarioids.We also identified phylogenetic signal for host-parasite associations with the probability of infection of Neotropical birds by any hemoparasite being more similar among more closely related species.We provided a useful framework to identify environments that correlate with hemoparasite infection,which is also helpful for detecting areas with potential suitability for hemoparasite infection due to land conversion and climate change. | Gabriel Massaccesi DE LA TORRE Karla Magalhães CAMPIÃO | 2021 | Integrative Zoology2021，16，5： | 0 |
| 17 | Cardiovascular rehabilitation in patients aged 70-year-old or older:benefits on functional capacity,physical activity and metabolic profile in younger vs.older patients显示文摘Background The benefits of exercise-based cardiac rehabilitation(EBCR)programs in post-acute myocardial infarction(AMI)patients have been demonstrated.Our aim was to assess the impact of EBCR in³70-years-old vs.younger post-AMI patients.Methods We retrospectively evaluated patients who underwent a supervised EBCR protocol,twice a week during 6-12 weeks.We evaluated changes in several outcomes based on pre-and post-CRP assessments.Results Of a total of 1607 patients,333(21%)were³70-years-old.After the EBCR,an overall improvement on functional capacity,daily physical activity,lipid profile,body mass index,glycated hemoglobin(HbA1c),N-terminal pro-brain natriuretic peptide(NT-pro-BNP)and C-reactive protein was observed in both younger and older patients(P<0.05).Older patients showed a smaller benefit on the increment of daily physical activity and lipid profile improvement,but a larger reduction in NT-pro-BNP.In the multivariate analysis,only improvements on daily physical activity and HbA1c were dependent on age.Conclusion As their younger counterparts,older patients,significantly improved functional capacity,metabolic parameters and level of daily physical activity after EBCR. | Marta Fontes-Oliveira Maria Trêpa Patrícia Rodrigues Preza Fernandes Sandra Magalhães Sofia Cabral Mário Santos Severo Torres | 2020 | Journal of Geriatric Cardiology2020，17，9： | 0 |
| 18 | The roles of anurans in antagonistic networks are explained by life-habit and body-size显示文摘Interactions among living beings are the structuring basis of ecosystems,and studies of networks allow us to identify the patterns and consistency of such interactions.Antagonistic networks reflect the energy flow of communities,and identifying network structure and the biological aspects that influence its stability is crucial to understanding ecosystem functioning.We used antagonistic anuran interactions-predator-prey and host-parasite-to assess structural patterns and to identify the key anuran species structuring these networks.We tested whether anuran body-size and life-habit are related to their roles in these networks.We collected individuals of 9 species of anurans from an area of the Atlantic Forest in Brazil and identified their prey and helminth parasites.We used network(modularity,specialization,and nestedness)and centrality metrics(degree,closeness,and betweenness)to identify the role of anuran species in both networks.We then evaluated whether anuran body-size or life-habit were related to anuran centrality using generalized linear mixed models.The networks formed specialized interactions in compartments composed by key species from different habits.In our networks,anurans with rheophilic and cryptozoic habit are central in predator-prey networks,and those with larger body size and arboreal and cryptozoic habit in the host-parasite network.This study represents a step towards a better understanding of the influential factors that affect the structure of anuran antagonist networks,as well as to recognize the functioning roles of anuran species. | Amanda Caroline DUDCZAK Gabriel Massaccesi DE LA TORRE Lorena EUCLYDES Karla Magalhães CAMPIÃO | 2022 | Integrative Zoology2022，17，4： | 0 |
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