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| 1 | Beneficial effects of hydrocortisone in induced acute pancreatitis of rats显示文摘背景很少被了解象细胞间的粘附 molecule-1 (ICAM-1 ) 和它的 counterreceptors 那样的房间粘附分子上的 hydrocortisone 的效果(LFA-1, Mac-1 ) 在尖锐胰腺炎(AP ) 。我们在老鼠的 AP 在 ICAM-1 和它的 counterreceptors ( LFA-1 和 Mac-1 )的生产上与 hydrocortisone 调查了优先的处理的效果在导致的尖锐 pancreatitis.Methods 上澄清 hydrocortisone 的效果尖锐胰腺炎被5% chenodeoxycholic 酸的注入导致进胰腺的管,由胰腺的管的结扎列在后面。在尖锐胰腺炎的正式就职前,老鼠与 hydrocortisone (n=20 ) 或 0.9%saline (n=20 ) 被对待。从胰和肺的血和标本在 1 个小时或 3 个小时从每处理 euthanized 从 5 只老鼠被获得, 6 个小时, 12 个小时。ICAM-1 的表示被 immunohistochemistry 和胰和肺的西方的污点分析估计。neutrophils 上的 LFA-1 和 Mac-1 的表达式被流动 cytometer.The 检测 hydrocortisone 的治疗学的效果从损害被估计到胰,在 hydrocortisone 组的胰的 lung.Results ICAM-1 表示是显著地不到在里面在 3 个小时和 6 个小时的控制组。在 hydrocortisone 组的肺, ICAM-1 表示是显著地不到在里面在 3 个小时, 6 个小时和 12 个小时的控制组。在血的 neutrophils 上的 LFA-1 和 Mac-1 的表达式在 hydrocortisone 组上在控制组显著地增加了。ICAM-1, LFA-1 和 Mac-1 的增加的表示先于白血球渗入。与尖锐胰腺炎作比较到未经治疗的动物,有 hydrocortisone 的老鼠 pretreated 显著地减少了组织学的肺损害并且在尖锐胰腺炎的正式就职改善以前,与 hydrocortisone 腹水的 fluid.Conclusions 输出优先的处理肺的损害和腹水的液体和还原剂的产量 ICAM-1 的表示和它的 counterreceptors ( LFA-1 , Mac-1 )在尖锐胰腺炎。 | SUN Wei WATANABE Yasuhiro TOKI Akira WANG Zhong-qiu | 2007 | Chinese Medical Journal2007，，20： | 7 |
| 2 | Reflection Asymmetric Relativistic Mean Field Approach and Its Application to the Octupole Deformed Nucleus ^226Ra显示文摘 | 耿立升 孟杰 Toki Hiroshi | 2007 | Chinese Physics Letters2007，24，7： | 6 |
| 3 | Chronic pancreatitis caused by an autoimmune abnormality显示文摘 | Kenji Yoshida Fumitake Toki Tadashi Takeuchi Shin-Ichiro Watanabe Keiko Shiratori Naoaki Hayashi | 1995 | Digestive Diseases and Sciences1995，，7： | 4 |
| 4 | Chronic pancreatitis caused by an autoimmune abnormality显示文摘 | Kenji Yoshida MD Fumitake Toki MD Tadashi Takeuchi MD Shin-Ichiro Watanabe MD Keiko Shiratori MD Naoaki Hayashi MD | 1995 | Digestive Diseases and Sciences1995，，7： | 2 |
| 5 | Chronic pancreatitis caused by an autoimmune abnormality显示文摘 | Kenji Yoshida MD Fumitake Toki MD Tadashi Takeuchi MD Shin-Ichiro Watanabe MD Keiko Shiratori MD Naoaki Hayashi MD | 1995 | Digestive Diseases and Sciences1995，，7： | 2 |
| 6 | Development and evaluation of FSSG: frequency scale for the symptoms of GERD显示文摘 | Motoyasu Kusano Yasuyuki Shimoyama Sayaka Sugimoto Osamu Kawamura Masaki Maeda Keiko Minashi Shiko Kuribayashi Tatsuya Higuchi Hiroaki Zai Kyoko Ino Tsutomu Horikoshi Tadashi Sugiyama Munetoshi Toki Tsuneo Ohwada Masatomo Mori | 2004 | Journal of Gastroenterology2004，，9： | 2 |
| 7 | Genomic structure of the whole D–J–C clusters and the upstream region coding V segments of the TRB locus in pig显示文摘 | Tomoko Eguchi-Ogawa Daisuke Toki Hirohide Uenishi | 2009 | Developmental and Comparative Immunology2009，，10： | 2 |
| 8 | Relativistic continuum Hartree Bogoliubov theory for ground-state properties of exotic nuclei显示文摘 | J. Meng H. Toki S.G. Zhou S.Q. Zhang W.H. Long L.S. Geng | 2005 | Progress in Particle and Nuclear Physics2005，，2： | 2 |
| 9 | Relationship between clinicopathological features and mucin phenotypes of advanced gastric adenocarcinoma显示文摘AIM: To investigate a relationship between the clinicopathological features and mucin phenotypes in advanced gastric adenocarcinoma (AGA). METHODS: Immunohistochemical staining was performed to determine the mucin phenotypes in 38 patients with differentiated adenocarcinomas (DACs), 9 with signet-ring cell carcinomas (SIGs), and 48 with other diffuse-type adenocarcinomas (non-SIGs) of AGA. The mucin phenotypes were classified into 4 types: gastric (G), gastrointestinal (GI), intestinal, and unclassified. RESULTS: The G-related mucin phenotypes were highly expressed in all the histological subtypes of AGA. The expression of the GI phenotype in SIG patients was lower than that in DAC patients (P = 0.02), and this phenotype was observed in 56% of the non-SIG patients in the intramucosal layer. Among non-SIG cases, the expression of the GI phenotype was significantly higherin patients with extended adenocarcinomas and those with positive rates of lymph node metastasis. There was no difference between the expressions of the G and other GI phenotypes factors. Among DAC and non-SIG patients, there were no differences between the survival rates of the corresponding patient groups. CONCLUSION: The GI phenotype might possess more invasive characteristics than the G phenotype in nonSIG. Neither of the phenotypes indicated a poor prognosis of DAC and non-SIG. | Fumiaki Toki Atsushi Takahashi Ryusuke Aihara Kyoichi Ogata Hiroyuki Ando Tetsuro Ohno Erito Mochiki Hiroyuki Kuwano | 2010 | World Journal of Gastroenterology2010，16，22： | 2 |
| 10 | nternational显示文摘 | Toki T Shiozawa T Hosake N Minimal deviation adenocarcinoma of the uterine cervix has abnormal ex pression of sex steroid receptors CA125 and gastric mucin | 1997 | J Gynecol Pathol1997，16，2： | 1 |
| 11 | Novel poly(vinyl alcohol)-degrading enzyme and the degradation mechanism 显示文摘 | MATSUMURA S TOMIZAWA N TOKI A NISHIKAWA K TOSHlMA K | 1999 | Macromolecules1999，32，： | 1 |
| 12 | Carcinoma related to choledochalcystswith interal drainage operations 显示文摘 | Todani T Watanabe Y Toki A | 1987 | Surg Gynecol Obstet1987，164，1： | 1 |
| 13 | Molecular and physiological evaluation of transgenic tobacco plants expressing a maize phospho enol pyruvate carboxylase gene under the control of the cauliflower mosaic virus 35S promoter显示文摘 | Hiroyuki Kogami Mariko Shono Takayoshi Koike Syuuichi Yanagisawa Katsura Izui Naoki Sentoku Shigeyuki Tanifuji Hirofumi Uchimiya Seiichi Toki | 1994 | Transgenic Research1994，，5： | 1 |
| 14 | Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease显示文摘 | Sasaki N Toki S Chowei H | 2001 | Brain Res2001，888，2： | 1 |
| 15 | Deformation behaviour of anisotropic dense sand under principal stress axis rotation显示文摘 | MIURA K M1URA S TOKI S | 1986 | Soils and Foundations1986，26，1： | 1 |
| 16 | Carcinoma related to choledochal cysts with internal drainage operations 显示文摘 | TODANI T WATANABE Y TOKI A | 1987 | Surg Gynecol Obstet1987，164，1： | 1 |
| 17 | Feedinginduced c-fos expression in the nucleus of the solitary tract and dorsal medullary reticular formation in neonatal rats显示文摘 | Hironaka S Shirakawa T Toki S | 2000 | Neuroscience Letters2000，293，3： | 1 |
| 18 | Clinical pancreatitis caused by autoimmune abnormality; proposal of the concept of autoimmune pancreatitis显示文摘 | YOSHIDA K TOKI F TAKEUCHI T | 1995 | Dig Dis Sci1995，40，7： | 1 |
| 19 | Plasma characterization of a 10-cm diameter microwave discharge ion thruster显示文摘 | Kuninaka F H Toki K | 2004 | Journal of Propulsion and Power2004，20，4： | 1 |
| 20 | IL-17A inhibits airway reactivity induced by respiratory syncytial virus infection during allergic airway inflammation显示文摘 | Newcomb D C Boswell M G Reiss S Zhou W Goleniewska K Toki S | 2013 | Thorax2013，68，： | 1 |
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