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| 1 | Ecological risk assessment of Cd and other heavy metals in soil-rice system in the karst areas with high geochemical background of Guangxi,China显示文摘Karst areas are widely distributed in China,and the soil derived in these areas is enriched with trace elements and has the typical characteristics of high geochemical background.Therefore,soil ecological risk has gradually attracted extensive attention.In this study,1090 sets of rice grains and paired rhizosphere soils were collected as research objects from the outcropped karst areas of carbonate rocks in Guangxi,and the concentration characteristics and influencing factors of heavy metals,such as Cd and As,in rice grains and the corresponding soils were studied.According to the Chinese Soil Environmental Quality Standard(GB 15618-2018),the proportion of karstic soil samples in Guangxi with heavy metal(As,Cd,Cr,Cu,Hg,Ni,Pb and Zn)concentrations that exceed the standard risk screening values was generally greater than that of surface soils in China or non-karstic soils in Guangxi.Notably,Cd and As were the most prominently enriched heavy metals in soils.According to the Chinese Food Safety Standard(GB 2762-2017),Pb in rice grains from the studied area did not exceed the standard;the exceedance rates of Cr,Hg,and inorganic As were only about 1%;and the exceedance rate of Cd was 12.5%.Soil Cd concentration increased gradually whereas the concentration and exceedance rate of Cd in rice grains decreased gradually with the increase of soil pH.Specifically,the exceedance rate of Cd in rice grains was only 4%when soil pH>6.5.The results indicated that the risk screening values of Cd element in the Chinese Soil Environmental Quality Standard are not satisfactorily applicable to the ecological risk assessment of Cd in karstic soils.Therefore,the recommended threshold values for the safe utilization and risk control of Cd in karstic soils was proposed so as to provide a basis for soil environmental quality hierarchization,pollution risk control and land safety zoning of agricultural land in karst areas in China. | Qiong YANG Zhongfang YANG Qizuan ZHANG Xu LIU Xiaoxiong ZHUO Tiansheng WU Lei WANG Xueji WEI Junfeng JI | 2021 | Science China Earth Sciences2021，64，7： | 5 |
| 2 | Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning显示文摘Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning.The present study sought to detect the influence of pine pollen on apoptosis-related proteins.Immunohistochemistry,western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning.Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax,Bcl-2 protein expression and increasing p53 protein expression. | Yanhong Luo Yaodong Wei Taizhong Wang Dongzhu Chen Tiansheng Lu Ruibo Wu Keke Si | 2012 | Neural Regeneration Research2012，7，12： | 4 |
| 3 | Joint PP and PS AVO inversion based on Zoeppritz equations显示文摘Considering Zoeppritz equations,reflections of PP and PS are only the function of ratios of density and velocity.So the inversion results will be the same if the ratios are the same but values of density,velocities of P-wave and S-wave are different without strict constraint.This paper makes efforts to explore nonlinear simultaneous PP and PS inversion with expectation to reduce the ambiguity of AVO analysis by utilizing the redundancy of multi-component AVO measurements.Accurate estimation of ratio parameters depends on independence of input data.There are only two independent AVO attributes for PP reflectivity (i.e.intercept and gradient) and two for PS reflectivity (i.e.pseudo-intercept and pseudo-gradient or extreme amplitude),respectively.For individual PP and PS inversion,the values of least-squares objective function do not converge around a large neighborhood of chosen true model parameters.Fortunately for joint PP and PS inversion the values of the least-squares objective function show closed contours with single minima.Finally the power function fitting is used to provide a higher precision AVO attributes than traditional polynomial fitting.By using the four independent fitting attributes (two independent attributes for PP and PS respectively),the inversion of four ratio parameters (velocities and densities) would be estimated with less errors than that in traditional method. | Xiucheng Wei Tiansheng Chen | 2011 | Earthquake Science2011，24，4： | 2 |
| 4 | Reservoir prediction using multi-wave seismic attributes显示文摘The main problems in seismic attribute technology are the redundancy of data and the uncertainty of attributes,and these problems become much more serious in multi-wave seismic exploration.Data redundancy will increase the burden on interpreters,occupy large computer memory,take much more computing time,conceal the effective information,and especially cause the 'curse of dimension'.Uncertainty of attributes will reduce the accuracy of rebuilding the relationship between attributes and geological significance.In order to solve these problems,we study methods of principal component analysis (PCA),independent component analysis (ICA) for attribute optimization and support vector machine (SVM) for reservoir prediction.We propose a flow chart of multi-wave seismic attribute process and further apply it to multi-wave seismic reservoir prediction.The processing results of real seismic data demonstrate that reservoir prediction based on combination of PP-and PS-wave attributes,compared with that based on traditional PP-wave attributes,can improve the prediction accuracy. | Ye Yuan Yang Liu Jingyu Zhang Xiucheng Wei Tiansheng Chen | 2011 | Earthquake Science2011，24，4： | 1 |
| 5 | 显示文摘 | Yue Xuejun Hong Tiansheng Xiang Wei | 2012 | Chinese Physics Letters2012，29，12： | 1 |
| 6 | Anti-inflammatory effects of curcumin in experimental spinal cord injury in rats显示文摘 | Wei Jin Jing Wang Tiansheng Zhu Baoyu Yuan Hongbin Ni Jian Jiang Handong Wang Weibang Liang | 2014 | Inflammation Research2014，，5： | 1 |
| 7 | Proteomics profiling of colorectal cancer progression identifies PLOD2 as a potential therapeutic target显示文摘Dear editors,Colorectal cancer(CRC)is the second leading cause of cancer deaths in developed countries[1].The malignant transformation from small clumps to cancer takes about 10 years[2].This study aimed to characterize proteomic dynamics associated with CRC development and progres-sion,and identify novel therapeutic targets for intercepting the underlying oncogenic processes.We have optimized pressure cycling technology(PCT)coupled with data-independent acquisition mass spectrometry(DIA-MS)for robust and reproducible proteomic analysis of biopsy-level formalin-fixed paraffin-embedded(FFPE)tissues[3]. | Yingkuan Shao Kailun Xu Xi Zheng Biting Zhou Xiuli Zhang Lin Wang Yaoting Sun Dan Li Ting Chen Jian Wang Shaojun Yu Lifeng Sun Xiaoming Xu Shaozhi Dai Huanhuan Gao Guan Ruan Wei Liu Xue Cai Tiansheng Zhu Lina Qi Jiani Chen Wangxiong Hu Xingyue Weng Yi Zhu Xueping Xiang Zhiyuan Hu Jinfan Li Lirong Chen Jimin Shao Shu Zheng Tiannan Guo | 2022 | Cancer Communications2022，42，2： | 0 |
| 8 | Biomimetic hydroxyapatite coating on the 3D-printed bioactive porous composite ceramic scaffolds promoted osteogenic differentiation via PI3K/AKT/mTOR signaling pathways and facilitated bone regeneration in vivo显示文摘The architecture and surface modifications have been regarded as effective methods to enhance the bi-ological response of biomaterials in bone tissue engineering.The porous architecture of the implanta-tion was essential conditions for bone regeneration.Meanwhile,the design of biomimetic hydroxyap-atite(HAp)coating on porous scaffolds was demonstrated to strengthen the bioactivity and stimulate osteogenesis.However,bioactive bio-ceramics such asβ-tricalcium phosphate(β-TCP)and calcium sili-cate(CS)with superior apatite-forming ability were reported to present better osteogenic activity than that of HAp.Hence in this study,3D-printed interconnected porous bioactive ceramicsβ-TCP/CS scaf-fold was fabricated and the biomimetic HAp apatite coating were constructed in situ via hydrothermal reaction,and the effects of HAp apatite layer on the fate of mouse bone mesenchymal stem cells(mBM-SCs)and the potential mechanisms were explored.The results indicated that HAp apatite coating en-hanced cell proliferation,alkaline phosphatase(ALP)activity,and osteogenic gene expression.Further-more,PI3K/AKT/mTOR signaling pathway is proved to have an important impact on cellular functions.The present results demonstrated that the key molecules of phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT)and mammalian target of rapamycin(mTOR)were activated after the biomimetic hydrox-yapatite coating were constructed on the 3D-printed ceramic scaffolds.Besides,the activated influence on the protein expression of Runx2 and BMP2 could be suppressed after the treatment of inhibitor HY-10358.In vivo studies showed that the constructed HAp coating promoted bone formation and strengthen the bone quality.These results suggest that biomimetic HAp coating constructed on the 3D-printed bioac-tive composite scaffolds could strengthen the bioactivity and the obtained biomimetic multi-structured scaffolds might be a potential alternative bone graft for bone regeneration. | Bizhi Tan Naru Zhao Wei Guo Fangli Huang Hao Hu Yan Chen Jungang Li Zemin Ling Zhiyuan Zou Rongcheng Hu Chun Liu Tiansheng Zheng Gang Wang Xiao Liu Yingjun Wang Xuenong Zou | 2023 | Journal of Materials Science & Technology2023，，5： | 0 |
| 9 | Atomically precise gold nanoclusters for healthcare applications显示文摘The potential application of gold nanoparticles(GNPs)in biomedicine has been extensively reported.However,there is still too much puzzle about their real face and potential health risks in comparison with the commercial drug molecules.The emergence of atomically precise gold nanoclusters(APGNCs)provides the opportunity to address the puzzle due to their ultrasmall size,defined molecular formula,editable surface engineering,available structures and unique physicochemical properties including excellent biocompatibility,strong luminescence,enzyme-like activity and efficient renal clearance,et al.Recently,these advantages of APGNCs also endow them promising performances in healthcare such as bioimaging,drug delivery,antibacterial and cancer therapy.Especially,their clear composition and structures like the commercial drug molecules facilitate the study of their functions and the structure-activity relationship in healthcare,which is essential for the guided design of APGNC nanomedicine.Therefore,this review will focus the advantages and recent progress of APGNCs in health care and envision their prospects for the future. | Tiansheng Wei Congcong Mi Yan Sun Yining Chen Xiaoyang Hu Zibao Gan Xiuwen Zheng | 2023 | Biomedical Engineering Communications2023，2，4： | 0 |
| 10 | Virtual Instrument Testing System for R~T Curve of the High Temperature Superconductor显示文摘College of Electrical Engineering, Yanshan University, Qinhuangdao hebei 066004)Qi, hanhong Tian,Yongjun, Wei,Yanjun Wang, Tiansheng(State Key Laboratory for Superconductor, Institute of Physics, Chinese Academy of Science, Beijing 100080)Zheng,DongningAbatract : A set of virtual instrument system based on Labview for measuring the R^T curve of the high temperature superconductor is designed in this paper. The control for the Current Source and nanovoltage meter is realized by the IEEE488 bus. The superconductivity is measured based on the zero resistance characteristics of the superconductor. The measurement is of high precision and of high speed. The man-machine interface is direct and friendly. | Qi,Hanhong TianYongjun Wei,Yanjun Wang,Tiansheng Zheng,Dongning | 2003 | 微计算机信息2003，19，12： | 0 |
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