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| 1 | Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma显示文摘Hepatobiliary cystadenomas (HBC) and cystadenocarci- nomas are rare cystic lesions. Most patients with these lesions are asymptomatic, but presentation with ob- structive jaundice may occur. The first patient presented with intermittent colicky pain and recurrent obstructive jaundice. Imaging studies revealed a polypoid lesion in the left hepatic duct. The second patient had recurrent jaundice and cholangitis. Endoscopic retrograde cholan- giopancreatography (ERCP) showed a cystic lesion at the confluence of the hepatic duct. In the third patient with intermittent jaundice and cholangitis, cholangioscopy re- vealed a papillomatous structure protruding into the left bile duct system. In the fourth patient with obstructive jaundice, CT-scan showed slight dilatation of the intrahe- patic bile ducts and dilatation of the common bile duct of 3 cm. ERCP showed filling of a cystic lesion. All patients underwent partial liver resection, revealing HBC in the specimen. In the fifth patient presenting with obstructive jaundice, ultrasound examination showed a hyperecho- genic cystic lesion centrally in the liver. The resection specimen revealed a hepatobiliary cystadenocarcinoma. HBC and cystadenocarcinoma may give rise to obstruc- tive jaundice. Evaluation with cross-sectional imaging techniques is useful. ERCP is a useful tool to differentiate extraductal from intraductal obstruction. | Deha Erdogan Olivier RC Busch Erik AJ Rauws Otto M van Delden Dirk J Gouma Thomas M van Gulik | 2006 | World Journal of Gastroenterology2006，12，35： | 26 |
| 2 | Results of percutaneous sclerotherapy and surgical treatment in patients with symptomatic simple liver cysts and polycystic liver disease显示文摘AIM: To evaluate the results of the treatment of simple liver cysts (solitary and multiple) and polycystic liver disease (PLD) using percutaneous sclerotherapy and/or surgical procedures in a single tertiary referral centre. METHODS: Retrospective analysis of 54 patients referred for evaluation and possible treatment of simple liver cysts (solitary and multiple) and PLD, from January 1997 to July 2006. RESULTS: Simple liver cysts were treated in 41 pts (76/) with a mean size of 12.6 cm. The most common reason for referral was abdominal pain or discomfort (85/). Percutaneous sclerotherapy was performed as initial treatment in 30 pts, showing cyst recurrence in 6 pts (20/). Surgical treatment was initially performed in 11 pts with cyst recurrence in 3 pts (27/). PLD was treated in 13 pts (24/) with a mean size of the dominant cyst of 13 cm. Percutaneous sclerotherapy for PLD was performed in 9 pts with recurrence in 7 pts (77.8/). Surgical treatment for PLD was undertaken in 4 pts (30.8/) with recurrence in all. Eventually, 2 pts with PLD in the presence of polycystic kidney disease underwent liver-and kidney transplantation because of deterioration of liver and kidney function. CONCLUSION: The majority of patients with simple liver cysts and PLD are referred for progressive abdominal pain. As initial treatment, percutaneous sclerotherapy is appropriate. Surgical deroofing is indicated in caseof cyst recurrence after percutaneous sclerotherapy. However, the results of percutaneous sclerotherapy and surgical treatment for PLD are disappointing. Partial liver resection is indicated when there is suspicion of a pre-malignant lesion. | Deha Erdogan Otto M van Delden Erik AJ Rauws Olivier RC Busch Johan S Lameris Dirk J Gouma Thomas M van Gulik | 2007 | World Journal of Gastroenterology2007，13，22： | 15 |
| 3 | Vitamin E and donepezil for the treatment of mild cognitive impairment 显示文摘 | Peterson RC Thomas RG Grundman M | 2005 | N Engl J Med2005，352，23： | 1 |
| 4 | Dust mite allergens and asthma:report of a second international workshop显示文摘 | Platts Mills TA Thomas WR Aalberse RC | 1992 | J Allergy Clin Immunol1992，89，5： | 1 |
| 5 | The clinical syndrome of mammary duct ectasia显示文摘 | Thomas WG Williamson RC Davies JD | 1982 | Br J Surg1982，69，7： | 1 |
| 6 | Indoor allergens and asthma:report of the Third International Workshop显示文摘 | Platts-Mills TA1 Vervloet D Thomas WR Aalberse RC Chapman MD | 1997 | J Allergy Clin Immunol1997，100，61： | 1 |
| 7 | Oral calcium inhibits rectal epithetlial prolixferation in familial adenomatous polyposis显示文摘 | Thomas MG Thomson JP Williamson RC | 1993 | Br J Surg1993，80，4： | 1 |
| 8 | Impact of neutropenia on delivering planned adjuvant chemotherapy:UK audit of primary breast cancer patients显示文摘 | Leonard RC Miles D Thomas R Nussey F UK Breast Cancer Neutropenia Audit Group | | 0，，： | 1 |
| 9 | Dust mite aller- gens and asthma: report of a second international workshop 显示文摘 | Platts-Mills TA Thomas WR Aalberse RC | 1992 | J Allergy Clin Immun1992，89，5： | 1 |
| 10 | Attenuation of p53 expression protects against focal ischemic damage in transgenic mice显示文摘 | Crumrine RC Thomas AL Morgan PF | 1994 | J Cereb Blood Flow Metab1994，14，6： | 1 |
| 11 | Blood pressure lowering for the prevention and treatment of diabetic kidney disease显示文摘 | Thomas MC Atkins RC | 2006 | Drugs2006，66，17： | 1 |
| 12 | Vitamin E and donepezil for the treatment of mild cognitive impair- ment 显示文摘 | Petersen RC Thomas RG Grundman M | 2005 | N Engl J Med2005，352，23： | 1 |
| 13 | Dust mite allergens and asthma: Report of the second international workshop 显示文摘 | Platts-Mills TA Thomas WR Aalberse RC | 1992 | Allergy Clin Immunol1992，89，： | 1 |
| 14 | Impact of neutropenia on delivering planned adjuvant chemotherapy : UK audit of primary breast cancer pafients显示文摘 | Leonard RC Miles D Thomas R | 2003 | Br J Cancer2003，89，11： | 1 |
| 15 | Cystitis glandularis显示文摘 | Thomas EB Wendel RC | 1968 | J Urol1968，100，4： | 1 |
| 16 | Vitamin E and donepezil for the treatment of mild cognitive impairment显示文摘 | Peterson RC Thomas RG Grundman M | 2005 | N Engl J Med2005，352，23： | 1 |
| 17 | Synaptic plasticity in the mesolimbic dopamine syst-em显示文摘 | Thomas MJ Malenka RC | 2003 | Science2003，358，： | 1 |
| 18 | Blood pressure control and risk of incident atrial fibrillation显示文摘 | Thomas MC Dublin S Kaplan RC | | 0，，10： | 1 |
| 19 | Vitamin E and donepezil for the treatment of mild cognitive impairment显示文摘 | Petersen RC Thomas RG Grundman M Bennett D Doody R Ferris S Galasko D Jin S Kaye J Levey A Pfeiffer E Sano M van Dyck CH Thal LJ Alzheimer's Disease Cooperative Study Group | | 0，，23： | 1 |
| 20 | Pigtail catheters used for percutaneous fluid drainage: comparison of performance characteristics显示文摘 | Macha DB Thomas J Nelson RC | 2006 | Radiology2006，238，3： | 1 |
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