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| 1 | 短暂性脑缺血发作的定义和评价:美国心脏协会/美国卒中协会卒中委员会、心血管外科和麻醉委员会、心血管放射学和介入委员会、心血管护理委员会和外周血管病跨学科委员会对医疗卫生专业人员发布的科学声明:美国神经病学学会确认该声明作为神经科医生继续教育工具的价值显示文摘本科学声明面向为短暂性脑缺血发作(transient ischemic attacks,TIA)患者提供医疗诊治的临床医生和相关医疗卫生人员。采用正规的证据复习方法对1990-2007年7月期间Medline数据库进行系统的文献检索,并运用证据表、汇总分析和病例资料的合并分析,对数据进行综合处理。本文支持以下基于组织学的TIA定义:局灶性脑、脊髓或视网膜缺血引起的短暂性神经功能障碍发作,且无急性脑梗死。TIA患者的近期卒中风险较高,可根据临床量表、血管影像学和磁共振弥散加权成像进行风险分层。诊断推荐包括:TIA患者应在发病24h内接受神经影像学评价,最好是应用包括弥散序列在内的MRI;应进行无创性颈部血管成像检查,最好是无创性颅内血管成像;对于未能确定血管病因的患者,TIA发病后应尽快进行心电图检查,也应考虑持续心电监测和超声心动图检查;应进行常规血液化验;对于发病72h内就诊并且ABCD^2评分≥3分(提示近期复发风险较高)或在门诊不能迅速完成诊断评价的TIA患者,应收入院治疗。 | J. Donald Easton Jeffrey L. Saver Gregory W. Albers Mark J. Alberts Seemant Chaturvedi Edward Feldmann Thomas S. Hatsukami Randall T. Higashida S. Claibome Johnston Chelsea S. Kidwell Helmi L. Lutsep Elaine Miller Ralph L. Sacco 李海峰 高翔(译) | 2009 | 国际脑血管病杂志2009,,9: | 86 |
| 2 | C-reactive protein is a prognostic indicator in patients with perihilar cholangiocarcinoma显示文摘AIM: To evaluate prognostic indicators for the outcome of patients with perihilar extrahepatic cholangiocarcinoma in an unselected cohort. METHODS: We retrospectively analyzed 98 patients with perihilar cholangiocarcinoma. Twenty-three patients (23.5%) underwent tumor resection. Patients with non- resectable tumors underwent either transpapillary or percutaneous transhepatic biliary drainage. Additionally, 32 patients (32.7%) received photodynamic therapy (PDT) and 18 patients (18.4%) systemic chemotherapy. Predefined variables at the time of diagnosis and characteristics considering the mode of treatment were entered into a Cox’s proportional hazards model. Included in the analysis were age, tumor stage following the modified Bismuth-Corlette classification, bilirubin, prothrombin time (PT), C-reactive protein (CRP), carbohydrate antigen 19-9 (CA19-9), history of weight loss, surgical resection, chemotherapy and PDT. RESULTS: The Kaplan-Meier estimate of overall median survival was 10.5 (95%CI: 8.4-12.6) mo. In the univariate analysis, low Bismuth stage, low CRP and surgical resection correlated significantly with better survival. In the multivariate analysis, only CRP (P = 0.005) and surgical resection (P = 0.029) were found to be independently predictive of survival in the cohort. Receiver operating characteristic (ROC) analysis identified a CRP level of 11.75 mg/L as the value associated with the highest sensitivity and specificity predicting a survival > 5 mo. Applying Kaplan-Meier analysis, patients with a CRP < 12 mg/L at the time of diagnosis had a signifi cantly longer median survival than patients with higher values (16.2 vs 7.6 mo; P = 0.009).CONCLUSION: This retrospective analysis identif ied CRP level at the time of diagnosis as a novel indicator for the prognosis of patients with perihilar cholangiocarcinoma. It should be evaluated in future prospective trials on this entity. | Thomas Gerhardt Sabine Milz Michael Schepke Georg Feldmann Martin Wolff Tilman Sauerbruch Franz Ludwig Dumoulin | 2006 | World Journal of Gastroenterology2006,12,34: | 5 |
| 3 | Ebola haemorrhagic fever显示文摘 | Heinz Feldmann Thomas W Geisbert | 2011 | The Lancet2011,,9768: | 3 |
| 4 | Application of a hexapole collision and reaction cell in ICP-MS Part Ⅱ:Analytical figures of merit and first applications显示文摘 | FELDMANN I JAKUBOWSKI N THOMAS C | 1999 | Fresenius'' Journal of Analytical Chemistry1999,365,5: | 1 |
| 5 | Definition and Evaluation of Transient Ischemic Attack: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardio显示文摘 | J Donald Easton Jeffrey L. Saver Gregory W. Albers Mark J. Alberts Seemant Chaturvedi Edward Feldmann Thomas S. Hatsukami Randall T. Higashida S Claiborne Johnston Chelsea S. Kidwell Helmi L. Lutsep Elaine Miller Ralph L. Sacco | 2009 | Stroke2009,,6: | 1 |
| 6 | Influence of impurities on crystallization kinetics of calcium sulfate dihydrate and hemihydrate in strong HCl-Ca Cl2 solutions显示文摘 | Thomas Feldmann George P Demopoulos | 2013 | Industrial&Engineering Chemistry Research2013,52,: | 1 |
| 7 | Infection with MERS-CoV causes lethal pneumonia in the common marmoset显示文摘 | Falzarano D de Wit E Feldmann F Rasmussen A L Okumura A Peng X Thomas M J van Doremalen N Haddock E Nagy L LaCasse R Liu T Zhu J McLellan J S Scott D P Katze M G Feldmann H Munster V J | 2014 | PLoS Pathog2014,10,10: | 1 |
| 8 | Ebola haemorrhagic fever显示文摘 | Heinz Feldmann Thomas W Geisbert | 2011 | 2011 (9768)2011,,9768: | 1 |
| 9 | Alarmins: awaiting a clinical response显示文摘 | Chan James K Roth Johnnes Oppenheim Joost J Tracey Kevin J Vogl Thomas Feldmann Marc Horwood Nicole Nanchahal Jagdeep | 2012 | EN2012,,8: | 1 |
| 10 | Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses显示文摘 | Thomas W. Geisbert Kathleen M. Daddario-DiCaprio Joan B. Geisbert Douglas S. Reed Friederike Feldmann Allen Grolla Ute Str?her Elizabeth A. Fritz Lisa E. Hensley Steven M. Jones Heinz Feldmann | 2008 | Vaccine2008,,52: | 1 |
| 11 | The Middle East respiratory syndrome coronavirus (MERS-CoV) does not replicate in Syrian hamsters 显示文摘 | de Wit E Prescott J Baseler L Bushmaker T Thomas T Lackemeyer MG Martellaro C Milne-Price S Haddock E Haagmans BL Feldmann H Munster VJ | 2013 | PLoS One2013,8,69: | 1 |
| 12 | PPA与出血性中风相关性显示文摘背景:PPA(phenylpropanolamine,苯丙醇胺)常见于食欲抑制药和咳嗽感冒药中,以往病例报告表明含PPA的药物与出血性中风有关,通常发生在首次使用后。为阐明二者相关性,我们设计了一项病例对照研究。方法:18~49岁的男、女性研究病例来自美国43所医院,其合格标准包括在参与项目前30天内发生蛛网膜下腔出血或颅内出血,而既往并无确诊的脑损伤史。采用随机电话拨号,为每个病例安排2例对照进行面访。结果:调查人群包括702名病例和1376名对照。女性服用含PPA食欲抑制药和出血性中风危险之间相关联的调整比值比为16.58(95%可信区间1.51~182.21,P=0.02);女性首次服用含PPA药物与出血性中风危险之间关联的调整比值比3.13(95%可信区间0.86~11.46,P=0.08),所有首次服用的PPA皆为咳嗽感冒药。男、女性调查人群服用含PPA药物与出血性中风危险二者关联的调整比值比为1.49(95%可信区间0.84~2.64.P=0.17);男、女性调查人群服用含PPA的咳嗽感冒药与出血性中风危险二者关联的调整比值比为1.23(95%可信区间0.68~2.24,P=0.49),服用舍PPA的食欲抑制药与出血性中风危险关联的调整比值比为15.92(95%可信区间1.38~184.13,p=0.03)。对男性的分析结果表明:服用含PPA的咳嗽感冒药未引起出血性中风危险增加,男性无一例使用? | Walter N. Kernan Catherine M. Viscoli Lawrence M. Brass Joseph P. Broderick Thomas Brott Edward Feldmann Lewis B. Morgenstern Janet Lee Wilterdink Ralph I. Horwitz 陈关君 | 2001 | 药物不良反应杂志2001,3,1: | 1 |
| 13 | Occurrence, fate and assessment of polar metamizole (dipyrone) residues in hospital and municipal wastewater 显示文摘 | Dirk F Feldmann Sebastian Zuehlke Thomas Heberer | 2008 | Chemosphere2008,71,9: | 1 |
| 14 | Ebola haemorrhagic fever显示文摘 | Heinz Feldmann Thomas W Geisbert | 2011 | The Lancet2011,,9768: | 1 |
| 15 | Ebola virus: unravelling pathogenesis to combat a deadly disease显示文摘 | Thomas Hoenen Allison Groseth Darryl Falzarano Heinz Feldmann | 2006 | Trends in Molecular Medicine2006,,5: | 1 |
| 16 | Major Risk Factors for Intracerebral Hemorrhage in the Young Are Modifiable显示文摘 | Edward Feldmann Joseph P. Broderick Walter N. Kernan Catherine M. Viscoli Lawrence M. Brass Thomas Brott Lewis B. Morgenstern Janet Lee Wilterdink Ralph I. Horwitz | 2005 | Stroke2005,,9: | 1 |
| 17 | Ebola haemorrhagic fever显示文摘 | Heinz Feldmann Thomas W Geisbert | 2011 | The Lancet . 2011 (9768)2011,,9768: | 1 |
| 18 | Ebola hae- morrhagic rever显示文摘 | HEINZ FELDMANN THOMAS W GEISBERT | 2011 | Lancet2011,377,9768: | 1 |
| 19 | An Overview to the Concept of Smart Coupling and Battery Management for Grid Connected Photovoltaic Battery System显示文摘The paper gives an overview on the need for smart coupling for battery management in grid integrated renewable energy system(RES).Grid integrated photovoltaic(PV) battery system,as being popular and extensively used has been discussed in the paper.Smart coupling refers to intelligent grid integration such that it can foresee local network conditions and issue battery power flow management strategy accordingly to shave the peak PV and peak load.Therefore,a need for predictive energy management arises for smart integration to the grid and supervision of the power flow in accordance to the grid conditions.This is also a running project at the Institute of Energy Systems(INES),Offenburg University of Applied Science,Germany since January,2015.The paper should provide insights to the motivation,need and gives an outlook to the features of desired predictive energy management system(PEMS). | Deepranjan Dongol Elmar Bollin Thomas Feldmann | 2015 | Journal of Electronic Science and Technology2015,13,4: | 0 |