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| 1 | Hyperhomocysteinemia independently causes and promotes atherosclerosis in LDL receptor-deficient mice显示文摘BackgroundHyperhomocysteine 是冠的心疾病(CHD ) 的一个独立风险因素。然而, hyperhomocysteine 是否影响动脉粥样硬化的前进,是不清楚的。在现在的学习,我们在低密度的脂蛋白在动脉粥样硬化的形成上检验了 hyperhomocysteine 的效果受体缺乏(LDLr −/−) mice.MethodsForty -- 八只 7-week-old LDLr −/− 老鼠被分到下列组:老鼠喂了一本标准啮齿类动物食谱(控制组) ,老鼠喂了一本高蛋氨酸的食谱(高蛋氨酸的组) ,老鼠喂了一本高脂肪的食谱(高脂肪的组) ,并且老鼠在蛋氨酸和脂肪(高蛋氨酸、高脂肪的组) 高喂了一本食谱。在 19, 23,和 27 个星期岁时,在在每个组的每间隔的四个鼠标是 sacrificed.ResultsAt 学习的结束,鼠标没在大动脉的湾穴和大动脉的表面显示出动脉粥样硬化患者损害直到在控制组旧的 27 个星期。然而,动脉粥样硬化患者损害在 19 个星期在另外的三个组发展了。大动脉的表面上的动脉粥样硬化患者损害的数量比在高脂肪的组在高蛋氨酸的组是更低的(P <0.001 ) 。在高蛋氨酸、高脂肪的组的大动脉的表面上的动脉粥样硬化患者损害是最严重的。在大动脉的湾穴的动脉粥样硬化患者损害的吝啬的区域比在高脂肪的组在高蛋氨酸的组与大动脉的表面上的动脉粥样硬化患者损害相比是更低的(P <0.001 ) 。在在高蛋氨酸、高脂肪的组的大动脉的湾穴的动脉粥样硬化患者损害是大多数 severe.ConclusionsHomocysteinemia 加速动脉粥样硬化患者损害并且在 LDLr −/− 老鼠独立地导致早动脉粥样硬化。减少 homocysteinemia 的水平可能为 CHD 的预防和处理是有益的。 | Hang-Yuan GUO Fu-Kang XU Hai-Tao LV Long-Bin LIU Zheng JI Xiao-Ya ZHAI Wei-Liang TANG Ju-Fang CH | 2014 | Journal of Geriatric Cardiology2014，11，1： | 23 |
| 2 | Necessity and indications of invasive treatment for Budd-Chiari syndrome显示文摘BACKGROUND:The development of collaterals in Budd-Chiari syndrome has been described and these collaterals play an important role in the presentation of this disease.These collaterals are diagnostic and their use in management strategy has never been evaluated.This study aimed to investigate the indications,feasibility and necessity of invasive treatment for patients with Budd-Chiari syndrome and to determine whether such a strategy is necessary for optimal management.METHODS:Twenty-nine patients who had been treated at our unit were enrolled in this study.Based on physical and biochemical examination,and hemodynamic compensation by collaterals,18 patients underwent radiological intervention (group A),while the other 11 had no invasive treatment (group B).The related hemodynamic parameters were acquired when percutaneous angiography was performed.RESULTS:In group A,all patients underwent successfully inferior vena cava (IVC) balloon angioplasty with or without stenting.Four patients also underwent hepatic vein angioplasty.In these patients,the mean IVC pressure before and after treatment was statistically different (29.3±9.2 vs 15.1±4.6 mmHg,P<0.01).The mean IVC pressure was much lower in group B than in group A (12.9±2.4 vs 29.3±9.2 mmHg,P<0.01),but there was no difference from that of the patients after radiological treatment (12.9±2.4 vs 15.1±4.6 mmHg,P>0.05).Median follow-up was 32.3 months (mean 21.3 months;range 3-61 months).In the course of follow-up,the patients in group A survived with good systemic status except for re-stenosis in one patient who underwent re-canalization of the IVC.In group B,10 patients had good systemic status except one patient who had a meso-caval shunt because of deterioration.CONCLUSIONS:The rationale of 'early diagnosis and early treatment' is not suitable for all patients with Budd-Chiari syndrome.Satisfactory survival can be achieved in some patients without invasive treatment,who are completely compensated by rich collaterals.Nonetheless,a positive treatment procedure should be performed if the patient's situation worsens in the course of regular follow-up. | Department of General Surgery (Fu Y,Sun YL,Ma XX,Xu PQ,Feng LS,Tang Z and Luo CH),Institute of Hepatic Vascular Disease (Sun YL),Department of Radiological Intervention (Guan S and Wang ZW),First Affiliated Hospital,Zhengzhou University School of Medicine,Zhengzhou 450052,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 10 |
| 3 | 急性缺血性脑卒中后低脉压与不良预后相关显示文摘众所周知,脉压与心脏功能、动脉僵硬度、体液状态和血管事件有关。该研究旨在探讨基于中国台湾地区脑卒中登记资料的急性缺血性脑卒中(acute ischemic stroke,AIS)患者入院时脉压的预后作用。 | 刘莉 叶鹏 Tang SC Yin JH Liu CH Sun MH Lee JT Sun Y Hsu CS Sun MC Lin CH Chen CH Lien LM Muo CH Jeng JS Hsu CY | 2017 | 中华高血压杂志2017，25，7： | 5 |
| 4 | Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture显示文摘 | Pan W Quarles LD Song LH Yu YH Jiao C Tang HB Jiang CH Deng HW Li YJ Zhou HH Xiao ZS | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 5 | Truncated hepatitis B virus RNA in human hepatocellular carcinoma: Its representation in patients with advancing age 显示文摘 | Beerheide W Zhou G Tang Y Edler L Schroeder CH | 1999 | Intervirology1999，42，： | 1 |
| 6 | Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts显示文摘 | Lasbury ME Tang X Durant PJ Lee CH | 2003 | Infect Immun2003，71，9： | 1 |
| 7 | The urokinase receptor and integrins in cancer progression显示文摘 | Tang CH Wei Y | 2008 | Cell Mol Life Sci2008，65，12： | 1 |
| 8 | PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats显示文摘 | Lin TH Yang RS Tang CH | 2007 | Bone2007，41，4： | 1 |
| 9 | Transient tumor fibro blast interactions increase tumor cell malignancy by a TGF beta mediated mechanism in a mouse xenograft model of breast caneer显示文摘 | Stuehen CH Busch JI Tang B et a! | 2010 | PLoS One2010，5，3： | 1 |
| 10 | An Adjustable Approach to Intuitionistic Fuzzy Soft Sets Based Decision Making显示文摘 | Jiang Y CH Tang Y Chen Q M | 2011 | Ap- plied Mathematical modeling2011，35，： | 1 |
| 11 | Attenuation of bone mass and increase of osteoclast formation in decoy receptor 3 transgenic mice显示文摘 | Tang CH Hsu TL Lin WW | | 0，，04： | 1 |
| 12 | Determination of concentration of cytosolic NADH - cytochrome b5 reductase in erythrocytes from normal chinese adults, neonates and patients with hereditary methemog|obinemia by double -antibody sanwich ELISA显示文摘 | Lan FH Tang YC Huang CH | 1998 | Acta Haematol1998，100，1： | 1 |
| 13 | Comorbidity profiles of chronic migraine sufferers in a National database in Taiwan显示文摘 | CHEN Yong - chen TANG CH NG K | 2012 | J Headache Pain2012，13，4： | 1 |
| 14 | Berberine suppresses neuroin- flammatory responses through AMP-activated protein kinase activation in BV-2 microglia显示文摘 | Lu DY Tang CH Chert YH | 2010 | J Cell Biochem2010，110，： | 1 |
| 15 | Design and manufacture of the fuel element for the 10 MW high temperature gascooled reactor显示文摘 | Tang CH | 2002 | Nucl Eng Design2002，218，： | 1 |
| 16 | Nosocomial out-break of infec-tion with multi-drug-resistant Acinetobacter baumannii in a medicalcenter in Taiwan 显示文摘 | Chang HL Tang CH Hsu YM | 2009 | Infect Control and Hosp Epidemiol2009，30，1： | 1 |
| 17 | Effects of high -pressure treatment on some physicochemical and functional properties of soy protein isolates显示文摘 | Wang XS Tang CH Li BS | 2008 | Food Hydrocolloids2008，，22： | 1 |
| 18 | An Adjustable Approach to In- tuitionistic Fuzzy Soft Sets Based Decision Making 显示文摘 | Jiang Y CH Tang Y Chert Q M | 2011 | Applied Mathematical Modeling2011，35，： | 1 |
| 19 | Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis显示文摘 | Tang CH Tan TW Fu WM | | 0，，： | 1 |
| 20 | Laparoscpic Cholecystectomy for Acute Cholecystitis:The Evolving Trend in an Institution显示文摘 | Chau CH Siu WT Tang CN etal | 2006 | Asian J Surg2006，29，3： | 1 |
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