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| 1 | CD24: from A to Z显示文摘作为到 CD24 的重要性的一篇遗嘱,包括适应免疫,发炎,自体免疫的疾病和癌症,有多样的兴趣的研究人员遇到了 CD24。CD24 是在许多癌症的 overexpressed 并且出现 oncogenic。在适应有免疫力的反应, CD24 是在 costimulation 富有的淋巴的机关的一个冗余的 costimulatory 分子,但是在测试的选择目标机关是必要的,例如大脑和皮肤。更最近的研究建议它可以在由树枝状的房间区别危险和联系病原体的分子的模式有一个角色。CD24 的生物学吸引人却糟糕听说。这里,我们总结与 CD24 联系为可以表明在多样的过程之中的内在的连接由 CD24 调停了的进一步的研究刺激新想法的主要调查结果。 | Xianfeng Fang Pan Zheng Jie Tang Yang Liu | 2010 | Cellular & Molecular Immunology2010，7，2： | 8 |
| 2 | Kalman Filtering in a Sensor Bandwidth Constrained Network显示文摘 | WEN Chenglin WEN Chenglin GE Quanbo GE Quanbo TANG Xianfeng TANG Xianfeng | 2009 | Chinese Journal of Electronics2009，18，4： | 6 |
| 3 | Long-term clinical observation of patients with acute and chronic complete spinal cord injury after transplantation of Neuro Regen scaffold显示文摘Spinal cord injury(SCI)often results in an inhibitory environment at the injury site.In our previous studies,transplantation of a scaffold combined with stem cells was proven to induce neural regeneration in animal models of complete SCI.Based on these preclinical studies,collagen scaffolds loaded with the patients’own bone marrow mononuclear cells or human umbilical cord mesenchymal stem cells were transplanted into SCI patients.Fifteen patients with acute complete SCI and 51 patients with chronic complete SCI were enrolled and followed up for 2 to 5 years.No serious adverse events related to functional scaffold transplantation were observed.Among the patients with acute SCI,five patients achieved expansion of their sensory positions and six patients recovered sensation in the bowel or bladder.Additionally,four patients regained voluntary walking ability accompanied by reconnection of neural signal transduction.Among patients with chronic SCI,16 patients achieved expansion of their sensation level and 30 patients experienced enhanced reflexive defecation sensation or increased skin sweating below the injury site.Nearly half of the patients with chronic cervical SCI developed enhanced finger activity.These long-term follow-up results suggest that functional scaffold transplantation may represent a feasible treatment for patients with complete SCI. | Fengwu Tang Jiaguang Tang Yannan Zhao Jiaojiao Zhang Zhifeng Xiao Bing Chen Guang Han Na Yin Xianfeng Jiang Changyu Zhao Shixiang Cheng Ziqiang Wang Yumei Chen Qiaoling Chen Keran Song Zhiwei Zhang Junjie Niu Lingjun Wang Qin Shi Liang Chen Huilin Yang Shuxun Hou Sai Zhang Jianwu Dai | 2022 | Science China(Life Sciences)2022，65，5： | 3 |
| 4 | The BZR1-EDS1 module regulates plant growth-defense coordination显示文摘Plants have developed sophisticated strategies to coordinate growth and immunity,but our understanding of the underlying mechanism remains limited.In this study,we identified a novel molecular module that reg-ulates plant growth and defense in both compatible and incompatible infections.This module consisted of BZR1,a key transcription factor in brassinosteroid(BR)signaling,and EDS1,an essential positive regulator of plant innate immunity.We found that EDS1 interacts with BZR1 and suppresses its transcriptional activ-ities.Consistently,upregulation of EDS1 function by a virulent Pseudomonas syringae strain or salicylic acid treatment inhibited BZR1-regulated expression of BR-responsive genes and BR-promoted growth.Furthermore,we showed that the cytoplasmic fraction of BZR1 positively regulates effector-triggered im-munity(ETI)controlled by the TIR-NB-LRR protein RPS4,which is attenuated by BZR1's nuclear transloca-tion.Mechanistically,cytoplasmic BZR1 facilitated AvrRps4-triggered dissociation of EDS1 and RPS4 by binding to EDS1,thus leading to efficient activation of RPS4-controlled ETI.Notably,transgenic expression of a mutant BZR1 that accumulates exclusively in the cytoplasm improved pathogen resistance without compromising plant growth.Collectively,these results shed new light on plant growth-defense coordina-tion and reveal a previously unknown function for the cytoplasmic fraction of BZR1.The BZR1-EDS1 mod-ule may be harnessed for the simultaneous improvement of crop productivity and pathogen resistance. | Guang Qi Huan Chen Dian Wang Hongyuan Zheng Xianfeng Tang Zhengzheng Guo Jiayu Cheng Jian Chen Yiping Wang Ming-yi Bai Fengquan Liu Daowen Wang Zheng Qing Fu | 2021 | Molecular Plant2021，14，12： | 1 |
| 5 | Time Domain Synchronous OFDM System for Optical Fiber Communications显示文摘A spectrum efficient OFDM scheme named Time Domain Synchronous-OFDM(TDS-OFDM)is introduced into coherent optical transmission system,in which the pseudo noise(PN)sequence is exploited as guard interval to realize frame synchronization,compensate the carrier frequency offset(CFO),and estimate and equalize channel simultaneously.Since there is no pilot signals or training symbols in TDS-OFDM,the proposed scheme can achieve higher spectral efficiency(SE)above 10%improvement comparing with CPOFDM.The proposed method is implemented and verified in a 28GBaud QPSK OFDM system and a 28GBaud 16QAM OFDM system.It is demonstrated that the proposed scheme shows high CFO estimation accuracy and synchronous accuracy.Under CFO and linewidth of laser source set as 100MHz and 100kHz respectively,BER of QPSK OFDM system is below 3.8e-3 at the optical signal-to-noise ratio(OSNR)of 13dB,and BER of 16QAM OFDM system is below 3.8e-3 at the OSNR of 20dB. | Chenxin Jing Xianfeng Tang Xiaoguang Zhang Lixia Xi Wenbo Zhang | 2019 | China Communications2019，16，9： | 1 |
| 6 | Formation and structure of LaNi2 intermetallic compound under high pressure显示文摘 | Liang Jin Ma Xianfeng Tang Jinkui | 2003 | Intermetallics2003，11，： | 1 |
| 7 | Nanostructured bulk novel hard material with “rounded” grains obtained by nanocrystalline “rounded” (W 0.5 Al 0.5 )C powders显示文摘 | Zhuhui Qiao Haijuan Wang Xianfeng Ma Wei Zhao Huaguo Tang | 2008 | Materials Science & Engineering A2008，，1： | 1 |
| 8 | A novel (W–Al)–C–Co composite cemented carbide prepared by mechanical alloying and hot-pressing sintering显示文摘 | Zhuhui Qiao Xianfeng Ma Wei Zhao Huaguo Tang Shuguang Cai Bo Zhao | 2007 | International Journal of Refractory Metals and Hard Materials2007，，3： | 1 |
| 9 | Progress and Perspective of the Cathode Materials towards Bromine-Based Flow Batteries显示文摘Bromine-based flow batteries(Br-FBs)have been one of the most promising energy storage technologies with attracting advantages of low price,wide potential window,and long cycle life,such as zinc-bromine flow battery,hydrogen-bromine flow battery,and sodium polysulfide-bromine flow battery.The research and development of aqueous Br-FBs are very fast and many achievements have been realized.However,Br-FBs suffer from the sluggish kinetics of Br_(2)/Br-redox couple and serious self-discharge caused by the diffusion of bromine,which hinder the further commercialization and industrialization of the aqueous Br-FBs.A series of mitigation strategies have been developed to figure out these challenges,especially the modifications on electrode materials.Electrode,one of the critical components in a Br-FB,provides the reactions sites for redox couples,upon which its properties exert a significant effect on the performance of Br-FBs.Up to now,extensive research has been carried out on electrode modifications to solve the aforementioned notorious issues of Br-FBs,including surface treatment and surface modification.In this review,various electrode materials and relevant modification approaches used for Br-FBs are overviewed and summarized.Moreover,the relevant mechanisms are illustrated deeply,providing comprehensive and available instruction to pursue and develop high-performance cathodes for Br-FBs with high power density and long lifespan. | Luyin Tang Wenjing Lu Huamin Zhang Xianfeng Li | 2022 | Energy Material Advances2022，，1： | 1 |
| 10 | Influence of Milling Parameters on Processed SurfaceResidualStress of Aluminum Alloy显示文摘 | Tang Qianqian Zhao Xianfeng Wang Dongdong | 2015 | Machine Tool and Hydraulics2015，，： | 1 |
| 11 | Fine-tuning brassinosteroid biosynthesis via 3′UTR-dependent decay of CPD mRNA modulates wood formation in Populus显示文摘Brassinosteroids(BRs)are plant hormones that regulate wood formation in trees.Currently,little is known about the post-transcriptional regulation of BR synthesis.Here,we show that during wood formation,fine-tuning BR synthesis requires 3′UTR-dependent decay of Populus CONSTITUTIVE PHOTOMORPHOGENIC DWARF 1(PdCPD1).Overexpression of PdCPD1 or its 3′UTR fragment resulted in a significant increase of BR levels and inhibited secondary growth.In contrast,transgenic poplars repressing PdCPD13′UTR expression displayed moderate levels of BR and promoted wood formation.We show that the Populus GLYCINE-RICH RNA-BINDING PROTEIN1(PdGRP1)directly binds to a GU-rich element in 3′UTR of Pd CPD1,leading to its mRNA decay.We thus provide a post-transcriptional mechanism underlying BRs synthesis during wood formation,which may be useful for genetic manipulation of wood biomass in trees. | Dian Wang Xiaoning Hao Li Xu Mengyan Zhao Congpeng Wang Xihao Yu Yingzhen Kong Mengzhu Lu Gongke Zhou Guohua Chai Xianfeng Tang | 2023 | Journal of Integrative Plant Biology2023，65，8： | 0 |
| 12 | Water-soluble Cu30 nanoclusters as a click chemistry catalyst for living cell labeling via azide-alkyne cycloaddition显示文摘Cu(I)-catalyzed azide-alkyne cycloadditions(CuAAC)have gained increasing interest in the selective labeling of living cells and organisms with biomolecules.However,their application is constrained either by the high cytotoxicity of Cu(I)ions or the low activity of CuAAC in the internal space of living cells.This paper reports the design of a novel Cu-based nanocatalyst,watersoluble thiolated Cu30 nanoclusters(NCs),for living cell labeling via CuAAC.The Cu30 NCs offer good biocompatibility,excellent stability,and scalable synthesis(e.g.,gram scale),which would facilitate potential commercial applications.By combining the highly localized Cu(I)active species on the NC surface and good structural stability,the Cu30 NCs exhibit superior catalytic activities for a series of Huisgen cycloaddition reactions with good recyclability.More importantly,the biocompatibility of the Cu30 NCs enables them to be a good catalyst for CuAAC,whereby the challenging labeling of living cells can be achieved via CuAAC on the cell membrane.This study sheds light on the facile synthesis of atomically precise Cu NCs,as well as the design of novel Cu NCs-based nanocatalysts for CuAAC in intracellular bioorthogonal applications. | Ge Yang Yali Xie Yaru Wang Ying Tang Leng Leng Chng Fuyi Jiang Fanglin Du Xianfeng Zhou Jackie Y.Ying Xun Yuan | 2023 | Nano Research2023，16，1： | 0 |
| 13 | Estimating leaf water content at the leaf scale in soybean inoculated with arbuscular mycorrhizal fungi from in situ spectral measurements显示文摘Leaf water content(LWC)of crops is a suitable parameter for evaluation of plant water status and arbuscular mycorrhizal effect on the host plant under drought stress.Remote sensing technology provides an effective avenue to estimate LWC in crops.However,few LWC retrieval models have been developed specifically for the arbuscular mycorrhizal inoculated crops.In this study,soybean with inoculation and non-inoculation treatments were planted under the severe drought,moderate drought and normal irrigation levels.The LWC changes under different treatments at the 30 th,45 th and 64 th day after the inoculation were investigated,and the spectral response characteristics of inoculated and non-inoculated soybean leaves under the three drought stresses were analyzed.Five types of spectral variables/indices including:raw spectral reflectance(R),continuum-removed spectral reflectance(R C),difference vegetation index(DVI),normalized difference vegetation index(NDVI)and ratio vegetation index(RVI)were applied to determine the best estimator of LWC.The results indicate that LWC decreased as the aggravating of drought stress levels.However,LWC in inoculated leaves was higher than that in the counterparts under the same drought stress level,and the values of raw reflectance measured at inoculated leaves were lower than the non-inoculated leaves,especially around 1900 nm and 1410 nm.These water spectral features were more evident in the corresponding continuum-removed spectral reflectance.The newly proposed DVI C(2280,1900)index,derived from the continuum-removed spectral reflectance at 2280 nm and the raw spectral reflectance at 1900 nm in DVI type of index,was the most robust for soybean LWC assessment,with R 2 value of 0.72(p<0.01)and root mean square error(RMSE)and mean absolute error(MAE)of 2.12%and 1.75%,respectively.This study provides a means to monitor the mycorrhizal effect on drought-induced crops indirectly and non-destructively. | Weiping Kong Wenjiang Huang Xianfeng Zhou Hugh Mortimer Lingling Ma Lingli Tang Chuanrong Li | 2019 | International Journal of Agricultural and Biological Engineering2019，12，6： | 0 |
| 14 | Acupuncture relieves chemotherapy-induced refractory hiccup: A report of two cases显示文摘The aim of the study was to present two cases that illustrate the beneficial effects of acupuncture on chemotherapy-induced refractory hiccup in cancer patients. This report described two patients with diffuse large B cell lymphoma(DLBCL) and right upper pulmonary lobe moderate-differentiation adenocarcinoma(p T1 N0 M0) who experienced chemotherapy-induced refractory hiccup. Alternative treatment was administered to relieve the symptoms of refractory hiccup. The patients were treated with acupuncture 30 min prior to chemotherapy. The selected acupoints included Zusanli(ST36), Taichong(LR3), Zhongwan(CV12), Jiuwei(RN15), and Neiguan(PC6). The symptoms related to chemotherapy-induced refractory hiccup were completely relieved after treatment with 2 to 3 cycles of acupuncture. Based on our experience, we conclude that these two cancer patients benefited from acupuncture treatment, suggesting that acupuncture not only plays a role in pain control, but is also effective in relieving chemotherapy-induced refractory hiccup in cancer patients. The beneficial outcomes need large-scale studies to examine the effectiveness of acupuncture treatment for relieving chemotherapy-induced refractory hiccup in cancer patients. | Xingyang Li Xianfeng Wang Yongquan Tang Tao Ren | 2017 | Oncology and Translational Medicine2017，3，5： | 0 |
| 15 | Wood forming tissue-specific expression of PdSuSy and HCHL increases holocellulose content and improves saccharification in Populus显示文摘Development of strategies to deconstruct lignocellulosic biomass in tree species is essential for biofuels and biomaterials production.We applied a wood forming tissue-specific system in a hybrid poplar to express both PdSuSy(a sucrose synthase gene from Populus deltoides×P.euramericana that has not been functionally characterized)and HCHL(the hydroxycinnamoyl-CoA hydratase-lyase gene from Pseudomonas fluorescens,which inhibits lignin polymerization in Arabidopsis).The PdSuSy-HCHL overexpression poplars correspondingly driven by the promoters of Arabidopsis AtCesA7 and AtC4 H resulted in a significant increase in cellulose(>8%),xylan(>12%)and glucose(>29%)content,accompanying a reduction in galacturonic acid(>36%)content,compared to control plants.The saccharification efficiency of these overexpression poplars was dramatically increased by up to 27%,but total lignin content was unaffected.These transgenic poplars showed inhibited growth characteristics,including>16%reduced plant height,>10% reduced number of internodes,and>18% reduced fresh weight after growth of 4 months,possibly due to relatively low expression of HCHL in secondary xylem.Our results demonstrate the structural complexity and interaction of the cell wall polymers in wood tissue and outline a potential method to increase biomass saccharification in woody species. | Yang Zhang Hua Xu Yingzhen Kong Jiawen Hua Xianfeng Tang Yamei Zhuang Yue Bai Gongke Zhou Guohua Chai | 2021 | Journal of Forestry Research2021，32，4： | 0 |
| 16 | Novel hard materials with controlled (W_(0.5)Al_(0.5))C grain shapes: in-situ high pressure preparation and mechanical properties显示文摘A novel hard material with various (W0.5Al0.5)C grain shapes was successfully prepared through mechanical alloying and in-situ high-pressure sintering process. X-ray diffraction apparatus and scanning electron microscopy were used to characterize the phase and the microstructures of the samples. The novel hard materials with 'fibrous', 'rounded' and 'plate-like' grains, which do not contain sharp edges, have the improved mechanical properties. The bulk boundless (W0.5Al0.5)C hard material with various (W0.5Al0.5)C grain shapes possesses good mechanical properties and light weight. The formation mechanism for the non-equilibrium (W0.5Al0.5)C grains during in-situ high-pressure sintering is also discussed. | Zhuhui QIA Xianfeng MA Huaguo TANG Wei ZHAO | 2012 | Acta Metallurgica Sinica(English Letters)2012，25，1： | 0 |
| 17 | Thermometric properties of Na_(2)Y_(2)TeB_(2)O_(10):Tb^(3+)green phosphor based on fluorescence/excitation intensity ratio显示文摘For noncontact optical thermometry,in contrast with fluorescence intensity ratio(FIR)technology,excitation intensity ratio(EIR)technology has been seriously limited due to low sensitivity.Moreover,by exploring all possible temperature-dependent response,developing multimode optical thermometry is of great importance.In this work,a new Na_(2)Y_(2)TeB_(2)O_(10):Tb^(3+)phosphor is obtained by a solid-state reaction.Based on FIR and EIR models of Tb',thermometric properties are studied thoroughly.Excellent relative and absolute sensitivity(S_(R)and S_(A))are acquired due to the significant difference in emission/excitation lines in response to temperature.Meanwhile,Tb^(3+)content-dependent luminescence quenching mechanism is discussed.This study shows a feasible route for exploiting well-performing FIR-/EIR-based thermometric materials. | Yuefei Xiang Lin Yang Canyuan Liao Xianfeng Xiang Xiangkai Tang Hanlin Tang Jing Zhu | 2023 | Journal of Advanced Ceramics2023，12，4： | 0 |
| 18 | Epidemiological characteristics and clinical manifestations of pediatric patients with COVID-19 in China: A multicenter retrospective study显示文摘Importance:The Coronavirus disease 2019(COVID-19)global pandemic poses a considerable challenge for pediatricians.Objective:This study aimed to identify the epidemiological characteristics and clinical features of pediatric patients with COVID-19 in China.Methods:This multicenter retrospective study included pediatric patients from 46 hospitals in China,covering 12 provinces and two municipalities.Epidemiological,demographic,clinical,laboratory,treatment,and outcome data were analyzed.Results:In total,211 pediatric patients with COVID-19 were included in this study.The median age was 7.0 years(range:22 days to 18 years).Approximately 16.3%of the patients exhibited asymptomatic infections,23.0%had upper respiratory tract infections,and 60.7%had pneumonia,including two with severe pneumonia and one with critical illness.Approximately 78.7%of the pediatric patients occurred in familial clusters.The most three common symptoms or signs at onset in children with COVID-19 were fever(54.5%),cough(49.3%),and pharyngeal congestion(20.8%).Only 17.6%of the patients presented with decreased lymphocyte count,whereas 13.6%had increased lymphocyte count.Among the patients with pneumonia who exhibited abnormal chest computed tomography findings,18.2%(23/127)of the patients had no other symptoms.Generally,the chest radiographs showed abnormalities that affected both lungs(49.6%);ground-glass opacity(47.2%)was the most common manifestation.The cure and improvement rates were 86.7%(183/211)and 13.3%(28/211),respectively.Only one patient with an underlying condition received invasive mechanical ventilation;none of the patients died.Interpretation:Similar to adults,children of all age groups are susceptible to COVID-19.Fortunately,most pediatric patients have mild symptoms or remain asymptomatic,despite the high incidence of pneumonia.Decreased proportions of white blood cells and lymphocytes are less frequent in children than in adults. | Yan Bai Liwei Gao Xianfeng Wang Lili Zhong Jingfeng Li Shenggang Ding Yuejie Zheng Jun Liu Yuxia Cui Lina Wang Mingfeng Han Jun Liu Xinping Jiang Min Jiang Junhua Li Ning Chen Yunxiao Shang Hourong Zhou Yi Xu Gen Lu Xing Chen Jizhi Xu Qihong Fan Yu Tang Jiang Wu Cen Li Xiaoxiang Yang Chunxi Chen Yonghong Yang Gary Wing-Kin Wong Adong Shen Tianyou Wang Runming Jin Baoping Xu Kunling Shen | 2021 | Pediatric Investigation2021，5，3： | 0 |
| 19 | Application of the CatBoost Model for Stirred Reactor State Monitoring Based on Vibration Signals显示文摘Stirred reactors are key equipment in production,and unpredictable failures will result in significant economic losses and safety issues.Therefore,it is necessary to monitor its health state.To achieve this goal,in this study,five states of the stirred reactor were firstly preset:normal,shaft bending,blade eccentricity,bearing wear,and bolt looseness.Vibration signals along x,y and z axes were collected and analyzed in both the time domain and frequency domain.Secondly,93 statistical features were extracted and evaluated by ReliefF,Maximal Information Coefficient(MIC)and XGBoost.The above evaluation results were then fused by D-S evidence theory to extract the final 16 features that are most relevant to the state of the stirred reactor.Finally,the CatBoost algorithm was introduced to establish the stirred reactor health monitoring model.The validation results showed that the model achieves 100%accuracy in detecting the fault/normal state of the stirred reactor and 98%accuracy in diagnosing the type of fault. | Xukai Ren Huanwei Yu Xianfeng Chen Yantong Tang Guobiao Wang Xiyong Du | 2024 | Computer Modeling in Engineering & Sciences2024，140，7： | 0 |
| 20 | Boost photothermal theranostics via self-assembly-induced crystallization(SAIC)显示文摘Owing to the intrinsic advantages of spatiotemporal selectivity,photothermal theranostics have become the advancing edge of precision medicine for cancer.Developing photothermal transduction agents(PTAs)with near-infrared(NIR)absorption,high photothermal conversion efficiency,robust photothermal stability,and good accumulation in tumors,is particularly valuable.Herein,we report a new concept,self-assembly-induced crystallization(SAIC),which can serve as a mechanism that dramatically boosts photothermal behaviors of PTA in NIR region.As a proof of concept,three heptamethine cyanine molecules with internal degrees of freedom(geometry and intramolecular interaction)are designed to fine-tune their crystallinity.Notably,Cy7-TCF-EMBI molecules with rigid and planar skeletons self-assemble into a crystalline state to maximize their packing density and improve the charge transfer,both of which contribute to nonradiative decay for energy dissipation as heat.The high packing density also renders an ideal scaffold for controlling intermolecular interactions to exhibit better photothermal stability,and endows an anisotropic three-dimensional architecture for passive tumor targeting.This“SAIC”strategy may offer a conceptually novel,practically simple but effective approach to unveil the structure–property relationship that could provide some general rules in rational design of PTAs,and paves the way for a next generation of supramolecular medicine for photothermal theranostics. | Xueluer Mu Fapu Wu Ying Tang Rui Wang Yajie Li Kaixuan Li Chunfeng Li Yingxi Lu Xianfeng Zhou Zhibo Li | 2022 | Aggregate2022，3，5： | 0 |
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