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    题名 作者 年代 出处 被引量
1射血分数正常心力衰竭的患病率和临床结局的变化趋势显示文摘Background: The prevalence of heart failure with preserved ejection fraction may be changing as a result of changes in population demographics and in the prevalence and treatment of risk factors for heart failure. Changes in the prevalence of heart failure with preserved ejection fraction may contribute to changes in the natural history of heart failure. We performed a study to define secular trends in the prevalence of heart failure with preserved ejection fraction among patients at a single institution over a 15-year period. Methods: We studied all consecutive patients hospitalized with decompensated heart failure at Mayo Clinic Hospitals in Olmsted County, Minnesota, from 1987 through 2001. We classified patients as having either preserved or reduced ejection fraction. The patients were also classified as community patients(Olmsted County residents) or referral patients. Secular trends in the type of heart failure, associated cardiovascular disease, and survival were defined. Results: A total of 6076 patients with heart failure were discharged over the 15-year period; data on ejection fraction were available for 4596 of these patients(76 percent). Of these, 53 percent had a reduced ejection fraction and 47 percent had a preserved ejection fraction. The proportion of patients with the diagnosis of heart failure with preserved ejection fraction increased over time and was significantly higher among community patients than among referral patients(55 percent vs. 45 percent). The prevalence rates of hypertension, atrial fibrillation, and diabetes among patients with heart failure increased significantly over time. Survival was slightly better among patients with preserved ejection fraction(adjusted hazard ratio for death, 0.96; P=0.01). Survival improved over time for those with reduced ejection fraction but not for those with preserved ejection fraction. Conclusions: The prevalence of heart failure with preserved ejection fraction increased over a 15-year period, while the rate of death from this disorder remained unchanged. These trends underscore the importance of this growing public health problem.Owan T.E. Hodge D.O. Herges R.M. M.M. Redfield 马超 2006世界核心医学期刊文摘(心脏病学分册)2006,,12:11
2Identification and Quantification of Aerosol Polar Oxygenated Compounds Bearing Carboxylic or Hydroxyl Groups.1.Method Development显示文摘In this study,a new analytical technique was developed for the identification and quantification of multifunctional compounds containing simultaneously at least one hydroxyl or one carboxylic group,or both.This technique is based on derivatizing first the carboxylic group(s) of the multifunctional compound using an alcohol (e.g.,methanol,1-butanol) in the presence of a relatively strong Lewisacid (BF3) as a catalyst.This esterification reaction quickly and quantitatively converts carboxylic acids to their ester forms.The second step is based on silylation of the ester compounds using bis(trimethylsilyl) trifluoroacetamide (BSTFA) as the derivatizing agent.For compounds bearing ketone groups in addition to carboxylic and hydroxyl groups,a third step was used based on PFBHA derivatizationof the carbonyls.Different parameters including temperature,reaction time,and effect due to artifacts were optimized.A GC/MS in EI and in methane-CI mode was used for the analysis of these compounds.The new approach was tested on a number of multifunctional compounds.The interpretation of their EI (70 eV) and CI mass spectra shows that critical information is gained leading to unambiguous identification of unknown compounds.For example,when derivatized only with BF3-methanol,their mass spectra comprise primary ions at m/z M ·+ +1,M ·+ +29,and M ·+ - 31 for compounds bearing only carboxylic groups and M ·+ +1,M ·+ +29,M ·+ -31,and M ·+ -17 for those bearing hydroxyl andcarboxylic groups.However,when a second derivatization (BSTFA) was used,compounds bearing hydroxyl and carboxylic groups simultaneously show,in addition to the ions observed before,ions at m/z M ·+ +73,M ·+ -15,M ·+ -59,M ·+ -75,M ·+ -89,and 73.To the best of our knowledge,this technique describes systematically for the first time a method for identifying multifunctional oxygenated compounds containing simultaneously one or more hydroxyl and carboxylic acid groups.Jaoui M. Kleindienst T.E. Lewandowski M. Edney E.O. 2004天然产物研究与开发2004,16,5:5
3老年性眼病研究项目中与病情严重的老年性黄斑变性发生有关的危险因素:第19号AREDS报道Milton R.C. Clemons T.E. Klien R. 张鹏 2005世界核心医学期刊文摘(眼科学分册)2005,0,11:4
4A multimedia, multiple pathway risk assessment of atrazine: the impact of age differentiated exposure including joint uncertainty and variability显示文摘DeborahH. Bennett W.E. Kastenberg T.E. McKone 1998Reliability Engineering and System Safety1998,,2:3
5单对直肠指诊获取的大便样本进行大便隐血筛查的准确性:与推荐的样本检查的比较Collins J.F. Lieberman D.A. Durbin T.E. Weiss D.G. 姜志茹 2005世界核心医学期刊文摘(胃肠病学分册)2005,0,6:2
6合作组织在美国流域管理中的作用显示文摘建立和保持合作关系是有效实施流域管理的关键所在。美国最为有效的流域管理都是通过公众参与、建立合作组织进行的,目的是识别和解决流域存在的各种问题。强调如果没有建立合作组织以及公众的参与和支持,就不可能实现有效的流域管理。T.E.达文波特 马小俊(译) 刘文(校) 2005水利水电快报2005,26,23:2
7OARSI guidelines for the non-surgical management of knee osteoarthritis显示文摘T.E. McAlindon R.R. Bannuru M.C. Sullivan N.K. Arden F. Berenbaum S.M. Bierma-Zeinstra G.A. Hawker Y. Henrotin D.J. Hunter H. Kawaguchi K. Kwoh S. Lohmander F. Rannou E.M. Roos M. Underwood 2014Osteoarthritis and Cartilage2014,,:2
8Impact of drying and re-wetting on N, P and K dynamics in a wetland soil显示文摘H. Olde Venterink T.E. Davidsson K. Kiehl L. Leonardson 2002Plant and Soil2002,,1:2
9Therapeutic trajectory following intra-articular hyaluronic acid injection in knee osteoarthritis – meta-analysis显示文摘R.R. Bannuru N.S. Natov U.R. Dasi C.H. Schmid T.E. McAlindon 2011Osteoarthritis and Cartilage2011,,6:2
10Predictors of outcome in patients requiring surgery for liver trauma显示文摘W.L. Sikhondze T.E. Madiba N.M. Naidoo D.J.J. Muckart 2006Injury2006,,1:1
11Case study feasibility analysis of renewable energy supply options for small to medium-sized tourist accommodations显示文摘G.J. Dalton D.A. Lockington T.E. Baldock 2008Renewable Energy2008,,4:1
12教育经济学纲要(辞目释义)显示文摘本期刊载两篇关于'教育经济学'的译稿。今后本刊还将选载关于'教育社会学'、'教育未来学'等等学科的编译稿,供研究、教学参考。T.E.韦锥 邱渊 1979全球教育展望1979,10,2:1
13The recent warming of permafrost in Alaska显示文摘T.E. Osterkamp 2005Global and Planetary Change2005,,3:1
14Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutrition显示文摘Richard D. Griffiths Christina Jones T.E. Allan Palmer 1997Nutrition1997,,4:1
15Micromechanics-based progressive failure analysis of fibre-reinforced composites with non-iterative element-failure method显示文摘X.S. Sun V.B.C. Tan T.E. Tay 2010Computers and Structures2010,,11:1
16The viability assessment of Microcystis aeruginosa cells after co-culturing with Bacillus mycoides B16 using flow cytometry显示文摘J.R. Gumbo T.E. Cloete G.J.J. van Zyl J.E.M. Sommerville 2014Physics and Chemistry of the Earth2014,,:1
17The effects of stress and stress hormones on human cognition: Implications for the field of brain and cognition显示文摘S.J. Lupien F. Maheu M. Tu A. Fiocco T.E. Schramek 2007Brain and Cognition2007,,3:1
18Estimates of biogenic emissions using satellite observations and influence of isoprene emission on O 3 formation over the eastern United States显示文摘Yiwen Xu M.L. Wesely T.E. Pierce 2002Atmospheric Environment2002,,38:1
19Cutting force prediction for five-axis ball-end milling considering cutter vibrations and run-out显示文摘S.B. Wang L. Geng Y.F. Zhang K. Liu T.E. Ng 2015International Journal of Mechanical Sciences2015,,:1
20Screening of microalgae with potential for biodiesel production and nutrient removal from treated domestic sewage显示文摘E.B. Sydney T.E. da Silva A. Tokarski A.C. Novak J.C. de Carvalho A.L. Woiciecohwski C. Larroche C.R. Soccol 2010Applied Energy2010,,10:1
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