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1Chronic Liver Failure-Sequential Organ Failure Assessment is better than the Asia-Pacific Association for the Study of Liver criteria for defining acute-on-chronic liver failure and predicting outcome显示文摘AIM:To compare the utility of the Chronic Liver FailureSequential Organ Failure Assessment(CLIF-SOFA)and Asia-Pacific Association for the Study of Liver(APASL)definitions of acute-on-chronic liver failure(ACLF)in predicting short-term prognosis of patients with ACLF.METHODS:Consecutive patients of cirrhosis with acute decompensation were prospectively included.They were grouped into ACLF and no ACLF groups as per CLIF-SOFA and APASL criteria.Patients were followed up for 3 mo from inclusion or mortality whichever was earlier.Mortality at 28-d and 90-d was compared between no ACLF and ACLF groups as per both criteria.Mortality was also compared between different grades of ACLF as per CLIF-SOFA criteria.Prognostic scores like CLIF-SOFA,Acute Physiology and ChronicHealth Evaluation(APACHE)-Ⅱ,Child-Pugh and Model for End-Stage Liver Disease(MELD)scores were evaluated for their ability to predict 28-d mortality using area under receiver operating curves(AUROC).RESULTS:Of 50 patients,38 had ACLF as per CLIFSOFA and 19 as per APASL criteria.Males(86%)were predominant,alcoholic liver disease(68%)was the most common etiology of cirrhosis,sepsis(66%)was the most common cause of acute decompensation while infection(66%)was the most common precipitant of acute decompensation.The 28-d mortality in no ACLF and ACLF groups was 8.3%and 47.4%(P=0.018)as per CLIF-SOFA and 39%and 37%(P=0.895)as per APASL criteria.The 28-d mortality in patients with no ACLF(n=12),ACLF grade 1(n=11),ACLF grade 2(n=14)and ACLF grade 3(n=13)as per CLIF-SOFA criteria was 8.3%,18.2%,42.9%and76.9%(χ2 for trend,P=0.002)and 90-d mortality was 16.7%,27.3%,78.6%and 100%(χ2 for trend,P<0.0001)respectively.Patients with prior decompensation had similar 28-d and 90-d mortality(39.3%and 53.6%)as patients without prior decompensation(36.4%and 63.6%)(P=NS).AUROCs for 28-d mortality were 0.795,0.787,0.739 and 0.710 for CLIF-SOFA,APACHE-Ⅱ,Child-Pugh and MELD scores respectively.On multivariate analysis of these scores,CLIF-SOFA was the only significant independent predictor of mortality with an odds ratio 1.538(95%CI:1.078-2.194).CONCLUSION:CLIF-SOFA criteria is better than APASL criteria to classify patients into ACLF based on their prognosis.CLIF-SOFA score is the best predictor of short-term mortality.Radha K Dhiman Swastik Agrawal Tarana Gupta Ajay Duseja Yogesh Chawla 2014World Journal of Gastroenterology2014,20,40:26
2Superconducting NbSe2 nanostructures 显示文摘Manashi N Swastik K Arup K R 2003Chemical Physics Letters2003,368,:1
3Two highly unsymmetrical tetradentate (N 3 O) Schiff base copper(II) complexes: Template synthesis, structural characterization, magnetic and computational studies显示文摘Ambarish Ray Dipankar Maity Anup Pramanik Kalyan K. Das Mahasweta Nandi Asim Bhaumik M. Nethaji Swastik Mondal Monika Mukherjee Mahammad Ali 2009Polyhedron2009,,17:1
4Minimal Hepatic Encephalopathy Impairs Quality Of Life显示文摘Swastik Agrawal Sridharan Umapathy Radha K. Dhiman 2014Journal of Clinical and Experimental Hepatology2014,,:1
5Superconducting NbSe2 nanostructures显示文摘MANASHI N SWASTIK K ARUP K R 2003Chemical Physics Letters2003,368,56:1
6Analysis of pathogenesis and risk factors associated with retinopathy of prematurity显示文摘Retinopathy of prematurity(ROP)is a disease associated with the vasculogenesis of the developing retina and in particular,in preterm newborns.The long term visual outcome of this disease includes increased risk of blindness and visual disabilities.The increasing prevalence of ROP,the leading cause of blindness in infants,necessitates the implementation of preventive measures to halt this trend,and this,most certainly,calls for the thorough understanding of the pathogenesis and various risk factors associated with the disease.Risk factors for ROP are among the main targets for improving health outcomes.Angiogenic factors including VEGF and IGF-1,maternal factors,oxidative stress and others(erythropoietin and inflammatory cytokines)are among the few of the most important risk factors that need to be addressed.A growing body of evidence suggests that subjects with ROP who have prenatal or postnatal risk factors are at increased risk of more severe ROP.These consistent observations have given rise to hopes of identifying the potential new risk factors and coming up with more efficient prevention and therapeutic strategies.However,studies focusing on incidence rates of ROP over time have painted an inconsistent picture.Individual studies have unequivocally demonstrated an association with the aforementioned risk factors,whereas epidemiological data however,is at best inconclusive.We have tried to integrate the studies,past and present,to identify the pathogenesis and novel risk factors.SWASTIK BIMB JIANG LI 2014东南大学学报(医学版)2014,33,4:1
7Absorption and emission modulation in a MoS2–GaN(0001) heterostructure by interface phonon–exciton coupling显示文摘Semiconductor heterostructures based on layered two-dimensional transition metal dichalcogenides(TMDs)interfaced to gallium nitride(Ga N)are excellent material systems to realize broadband light absorbers and emitters due to their close proximity in the lattice constants.The surface properties of a polar semiconductor such as Ga N are dominated by interface phonons,and thus the optical properties of the vertical heterostructure are influenced by the coupling of these carriers with phonons.The activation of different Raman modes in the heterostructure caused by the coupling between interfacial phonons and optically generated carriers in a monolayer MoS_2–Ga N(0001)heterostructure is observed.Different excitonic states in MoS_2 are close to the interband energy state of intraband defect state of Ga N.Density functional theory(DFT)calculations are performed to determine the band alignment of the interface and revealed a type-I heterostructure.The close proximity of the energy levels and the excitonic states in the semiconductors and the coupling of the electronic states with phonons result in the modification of carrier relaxation rates.Modulation of the excitonic absorption states in MoS_2 is measured by transient optical pump-probe spectroscopy and the change in emission properties of both semiconductors is measured by steady-state photoluminescence(PL)emission spectroscopy.There is significant red-shift of the C excitonic band and faster dephasing of carriers in MoS_2.However,optical excitation at energy higher than the bandgap of both semiconductors slows down the dephasing of carriers and energy exchange at the interface.Enhanced and blue-shifted PL emission is observed in MoS_2.Ga N band-edge emission is reduced in intensity at room temperature due to increased phonon-induced scattering of carriers in the Ga N layer.Our results demonstrate the relevance of interface coupling between the semiconductors for the development of optical and electronic applications.YUBA POUDEL JAGODA SLAWINSKA PRIYA GOPAL SAIRAMAN SEETHARAMAN ZACHARIAH HENNIGHAUSEN SWASTIK KAR FRANCIS D'SOUZA MARCO BUONGIORNO NARDELLI ARUP NEOGI 2019Photonics Research2019,7,12:0
8Graphene-aluminum nitride NEMS resonant infrared detector显示文摘The use of micro-/nanoelectromechanical resonators for the room temperature detection of electromagnetic radiation at infrared frequencies has recently been investigated,showing thermal detection capabilities that could potentially outperform conventional microbolometers.The scaling of the device thickness in the nanometer range and the achievement of high infrared absorption in such a subwavelength thickness,without sacrificing the electromechanical performance,are the two key challenges for the implementation of fast,high-resolution micro-/nanoelectromechanical resonant infrared detectors.In this paper,we show that by using a virtually massless,high-electrical-conductivity,and transparent graphene electrode,floating at the van der Waals separation of a few angstroms from a piezoelectric aluminum nitride nanoplate,it is possible to implement ultrathin(460 nm)piezoelectric nanomechanical resonant structures with improved electromechanical performance(450% improved frequency×quality factor)and infrared detection capabilities(4100×improved infrared absorptance)compared with metal-electrode counterparts,despite their reduced volumes.The intrinsic infrared absorption capabilities of a submicron thin graphene–aluminum nitride plate backed with a metal electrode are investigated for the first time and exploited for the first experimental demonstration of a piezoelectric nanoelectromechanical resonant thermal detector with enhanced infrared absorptance in a reduced volume.Moreover,the combination of electromagnetic and piezoelectric resonances provided by the same graphene–aluminum nitride-metal stack allows the proposed device to selectively detect short-wavelength infrared radiation(by tailoring the thickness of aluminum nitride)with unprecedented electromechanical performance and thermal capabilities.These attributes potentially lead to the development of uncooled infrared detectors suitable for the implementation of high performance,miniaturized and power-efficient multispectral infrared imaging systems.Zhenyun Qian Yu Hui Fangze Liu Sungho Kang Swastik Kar Matteo Rinaldi 2016Microsystems & Nanoengineering2016,2,1:0
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