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| 1 | Gut microbiota-related complications in cirrhosis显示文摘Gut microbiota plays an important role in cirrhosis. The liver is constantly challenged with commensal bacteria and their products arriving through the portal vein in the so-called gut-liver axis. Bacterial translocation from the intestinal lumen through the intestinal wall and to mesenteric lymph nodes is facilitated by intestinal bacterial overgrowth, impairment in the permeability of the intestinal mucosal barrier, and deficiencies in local host immune defences. Deranged clearance of endogenous bacteria from portal and systemic circulation turns the gut into the major source of bacterialrelated complications. Liver function may therefore be affected by alterations in the composition of the intestinal microbiota and a role for commensal flora has been evidenced in the pathogenesis of several complications arising in end-stage liver disease such as hepatic encephalopathy, splanchnic arterial vasodilatation and spontaneous bacterial peritonitis. The use of antibioticsis the main therapeutic pipeline in the management of these bacteria-related complications.However,other strategies aimed at preserving intestinal homeostasis through the use of pre-,pro-or symbiotic formulations are being studied in the last years.In this review,the role of intestinal microbiota in the development of the most frequent complications arising in cirrhosis and the different clinical and experimental studies conducted to prevent or improve these complications by modifying the gut microbiota composition are summarized. | Isabel Gómez-Hurtado José Such Yolanda Sanz Rubén Francés | 2014 | World Journal of Gastroenterology2014，20，42： | 12 |
| 2 | Protective effect of Bifidobacterium pseudocatenulatum CECT 7765 against induced bacterial antigen translocation in experimental cirrhosis显示文摘 | Alba Moratalla Isabel Gómez‐Hurtado Arlette Santacruz ángela Moya Gloria Peiró Pedro Zapater José M. González‐Navajas Paula Giménez José Such Yolanda Sanz Rubén Francés | 2014 | Liver Int2014，，6： | 2 |
| 3 | Immobilization and intracellular delivery of an anticancer drug using mussel-inspired polydopamine capsules显示文摘 | Cui J Yan Y Such G K Liang K Ochs C J Postma A Caruso F | 2012 | Biomacromolecules2012，13，8： | 1 |
| 4 | Aging and problems in differential diagnosis of psy-choorganic syndromes显示文摘 | Molnar G Glaub T Such A Bazsane KZ Pek G Csiky-MeszarosM | 1993 | Arch Gerontol Geriatr1993，16，2： | 1 |
| 5 | 查看详情显示文摘 | Ferguson C J Hughes R J Nguyen D Pham B T T Gilbert R G Serelis A K Such C H Hawkett B S | | 0，，06： | 1 |
| 6 | Changes in alveolar and cisternalcompartments induced by milking interval in the udder of dairy ewes显示文摘 | Castillo V Such X Caja G | 2008 | DairySci2008，91，9： | 1 |
| 7 | Next generation, sequentially assembled ultrathin films: beyond electrostatics显示文摘 | Quinn J F Johnston A P R Such G K Zelikin A N Caruso F | | 0，，05： | 1 |
| 8 | Lowfouling poly (N-vinyl pyrrolidone) capsules with engineered degradable properties 显示文摘 | Cameron R K Georgina K Such Gema A G | 2009 | Biomacromolecules2009，10，： | 1 |
| 9 | Toward therapeutic delivery with layer-by-layer engineered particles 显示文摘 | YAN Yan SUCH G K JOHNSTON A P R | 2011 | ACS Nano2011，5，6： | 1 |
| 10 | Bitumens and modified bitumens : Re- lationships, structures, properties and composition显示文摘 | RAMOND G SUCH C | 1990 | Bulle- tin de Liaison des Laboratoires des Ponts et Chausses1990，168，： | 1 |
| 11 | Control of photochromism through local environment effects using living radical polymerization显示文摘 | Such G K Evans R A Davis T P | 2004 | Macromolecule2004，，37： | 1 |
| 12 | Biodegradable click cap- sules with engineered drug-loaded multilayers显示文摘 | Ochs C J Such G K Yan Y | 2010 | Nano2010，4，3： | 1 |
| 13 | Next gen- eration, sequentially assembled ultrathin films: beyond e- lectrostatics 显示文摘 | QUINN J F JOHNSTON A P SUCH G K | 2007 | Chemical Society Reviews2007，36，5： | 1 |
| 14 | Bypassing rmiltidrug resistance in cancer cells with biodegradable polymer capsules显示文摘 | Yan Y Ochs C J Such G K | 2010 | Advanced Materials2010，22，47： | 1 |
| 15 | Assembly of ultrathin polymer multilayer films by click chemistry 显示文摘 | Such G K Quinn J F Quinn A | 2006 | J Am Chem Soc2006，128，： | 1 |
| 16 | Polyelectrolyte blend multilayers: a versatile route to engineering interfaces and films显示文摘 | Quinn A Such G Quinn JF | 2008 | Adv Funet Mater2008，18，1： | 1 |
| 17 | 查看详情显示文摘 | Ferguson C J Hughes R J Nguyen D Pham B T T Gilbert R G Serelis A K Such C H Hawkett B S | | 0，，： | 1 |
| 18 | Effects of once versus twice daily milking throughout lactation on milk yield and milk composition in dairy goats显示文摘 | Salama A A K Such X Caja G | 2003 | Journal of Dairy Science2003，86，5： | 1 |
| 19 | Reboxetine vs venlafaxine in the treatment of severe major depression 显示文摘 | SCHWARTZ G SUCH P SCHATZBERG A | 2002 | Eur Neuropsychopharmacol2002，12，3： | 1 |
| 20 | Factors influencing photochromism of spiro-compounds within polymeric matrices显示文摘 | SUCH G EVANS R A YEE L H | 2003 | Journal of Macromolecular Science Polymer Reviews2003，43，4： | 1 |
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