|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Peroral cholangioscopy:Update on the state-of-the-art显示文摘Peroral cholangioscopy(POC)is an endoscopic procedure that allows direct intraductal visualization of the biliary tract.POC has emerged as a vital tool for indeterminate biliary stricture evaluation and treatment of difficult biliary stones.Over several generations of devices,POC has fulfilled additional clinical needs where other diagnostic or therapeutic modalities have been inadequate.With adverse event rates comparable to standard endoscopic retrograde cholangioscopy and unique technical attributes,the role of POC is likely to continue expand.In this frontiers article,we highlight the existing and growing clinical applications of POC as well as areas of ongoing research. | Amith Subhash James L Buxbaum James H Tabibian | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，2： | 4 |
| 2 | Effect of hydroalcoholic extract of Hibiscus rosa sinensis Linn.leaves in experimental colitis in rats显示文摘Objective:To elucidate the ameliorative effect of liydrualcuholic extract of leaves of Hibiscus rosa sinensis(HRS) in acetic acid induced experimental colitis in male wistar rats.Methods: The animals were administered with 2 mL acetic acid(4%) via intra rectal.The animals were divided into various treatment groups(n=6).Prednisolone was used as standard drug and HRS was administered at a dose of 50,100 and 200 mg/kg p.o.The control group of animals received 1 mL of vehicle(distilled water).Ulcer area,ulcer index,spleen weight,colon weight to length ratio, macroscopic score,haemalological parameters,colonic superoxide dismutase(SOD),glutathione(GSH),myeloperoxidase(MPO),malondialdchyde(MDA),tumor necrosis factor-α(TNK- α), nitric oxide(NO) and histological changes were recorded after the treatment regimen of 11 days. Results:Intrarectal instillation of acetic acid caused enhanced ulcer area,ulcer index,spleen weight,colon weight to length ratio,colonic MPO,MDA,NO and TNF-α It caused significant decreased level of SOD and GSH.Pretreatment with HRS for 7 days exhibited significant effect in lowering of oxidative stress,colonic NO,TNF- α and elevation of SOD and GSH at a dose of 100 and 200 mg/kg in acetic acid induced colilis.Conclusions:The present investigation demonstrates HRS is of potent therapeutic value in the amelioration of expcrimenlal colilis in laboralory animals by inhibiting the proinflammatory mediator like NO and TNK-α. | Amit D Kandhare Kiran S Raygude Pinaki Ghosh Arvindkumar E Ghule Tejas P Gosavi Sachin L Badole Subhash L Bodhankar | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，5： | 2 |
| 3 | Ameliorative effects of standardized extract from Trigonella foenum-graecum L.seeds on painful peripheral neuropathy in rats显示文摘Objective:To evaluate the effects of the standardized extract of fenugreek(Trigonella foenumgraecum L.Family:Leguminasae) seed(IND01) in animal models of peripheral neuropathy. Methods:IND01 was prepared from fenugreek seeds and standardized by high performance liquid chromatography to a marker compound,trigonelline.The effects of daily oral administration of IND01(50,100 and 200 mg/kg) were studied in rats after partial sciatic nerve ligation(PSNL) and sciatic nerve crush injury(SNCI) during 30-days period.The measurements on thermal hyperalgesia(TH),motor function test(MFT) score and motor nerve conduction velocity (MNCV) were recorded.Results:IND01 offered sustained protection against TH and deranged MFT scores in both models from 7-day onwards.Fifteen days of daily oral administration of IND01 restored MNCV reduction in rats with SNCI but not with PSNL.Conclusions:IND01 was found to be effective in rat models of painful peripheral neuropathy. | Aashish S Morani Subhash L Bodhankar V Mohan Prasad A Thakurdesai | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，5： | 2 |
| 4 | In vitro antioxidant and antimicrobial activity cycloart-23-ene-3β,25-diol(B2) isolated from Pongamia pinnata(L.Pierre)显示文摘Objective:To evaluate the in-vitro antioxidant and antimicrobial activity of cvcloart-23- ene-3β,25-diol(called as B2) isolated from stem bark of Pongamia pinnata.Methods:In vitro antioxidant activity of B2 was determined by methods for determination of Dl’PH radical scavenging,reducing power,superoxide anion radical scavenging,hydroxyl radical scavenging, hydrogen peroxide scavenging,metal chelating and nitric oxide radical scavenging at the doses of 20.40.60.80 and 100μg/mL,respectively.3 -tocopherol with same concentration was used as a standard antioxidant.In vitro antimicrobial activity of B2 was determined by cup plate method in different concentration range of 10-100μg/mL.Results:The results indicated that dose dependent%reduction against DPPH radical,reducing power,superoxide anion radical scavenging,hydroxyl radical scavenging,metal chelating,hydrogen peroxide scavenging and nitric oxide radical scavenging by B2 andβ-tocopherol.Conclusions:It is concluded that cycloart 23-ene-3β,25 diol(B2) showed dose dependent antioxidant activity.B2 showed more DPPH radical scavenging,reducing power,superoxide scavenging,hydroxyl radical scavenging, metal chelating scavenging,hydrogen peroxide radical scavenging and nitric oxide radical scavenging activity thanβ-tocopherol and in case of antimicrobial activity B2 exhibited broad-spectrum activ ity against bacteria and strong activity against yeast type of fungi. | Sachin L Badole Anand A Zanwar Abhijeet N Khopade Subhash L Bodhankar | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，11： | 2 |
| 5 | Effects of cell shape and cell wall thickness variations on the elastic properties of two- dimensional cellular solids显示文摘 | Li K Gao X L Subhash G | 2005 | International Journal of Solids and Structures2005，42，5： | 1 |
| 6 | Creep and microstructural stability of dispersion strengthened Al-Fe-V-Si alloy显示文摘 | SUBHASH C KHATRI ALAN L | 1993 | Mater Sci and Eng1993，167，： | 1 |
| 7 | An evaluation of SERVQUAL and patient loyalty in an emerging country context显示文摘 | Subhash L Dennis M Mehves T | 2010 | Total Qual Manag Business Excellence2010，21，8： | 1 |
| 8 | A Computational Approach for the Classification of FEM Axisymmetric Stress as per ASME Code显示文摘 | Narasaiah G L Subhash G | 1986 | Pressure Vessel and Piping Technology1986，109，： | 1 |
| 9 | Potential use of mine tailings and fly ash in concrete 显示文摘 | Sunil B M Manjunatha L S Lolitha Ravi Subhash C Yaragal | 2015 | Advances in Concrete Construction2015，3，1： | 1 |
| 10 | Heat shock genes-integrating cell survival and death显示文摘 | Richa A Moushami M Subhash C L | 2007 | J Biosci2007，32，3： | 1 |
| 11 | Protective effect of aqueous extract of Feronia elephantum correa leaves on thioacetamide induced liver necrosis in diabetic rats显示文摘Objective:To evalueate hepatoprotective effects Feronia elephantum(F.elephantum)correa against thioacctamide(TA)induced liver necrosis in diabetic rats.Methods:Male wistar rats were made diabetic with alloxan(160 mg/kg)on day 0 of the study.They were intoxicated with hepatotoxicant(thioacetamide,300 mg/kg,ip)on day 9 of study to produce liver necrosis.Effects of 7 day daily once administration(day 2 to day 9)of EF(400 and 800 mg/kg,po)were evaluated on necorosis of liver in terms of mortality,liver volume,liver weight,serum aspartate aminotransferase(AST)and serum alanine transaminase(ALT),and histopathology of liver sections(for signs of necorosis and inflammation)on day-9 of the study.Separate groups of rats with treated only with alloxan(DA control),thioacetamide(TA control)and both(TA+DA control)were maintained.Results:FE significantly lowered the mortality rate and showed improvement in liver function parameters in TA-induced diabetic rats without change in liver weight,volume and serum glucose levels.Conclusions:FE showed promising activity against TA-induced liver necorsis in diabetic rats and so might be useful for prevention of liver complications in DM. | Prashant Sharma Subhash L Bodhankar Prasad A Thakurdesai | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，9： | 1 |
| 12 | Characterization of uniaxial compressive response of bulk amorphous Zr - Ti - Cu - Ni - Be alloy 显示文摘 | SUBHASH G DOWDING R J KECSKES L J | 2002 | Mater Sci Eng A2002，334，： | 1 |
| 13 | Characterization of uniaxial compressive response of bulk amorphous Zr-Cu-Ni-Be alloy显示文摘 | SUBHASH G DOWDING R J KECSKES L J | 2002 | Materials Science and Engineering A2002，334，： | 1 |
| 14 | Two new expanding cavity models for indentation deformations of elastic strain hardening materials显示文摘 | GAO X L JING X N SUBHASH G | 2006 | Int J Solids Struct2006，43，： | 1 |
| 15 | Characterization of based bulk metallic glasses for kinetic energy penetrators Zr-Ti-Cu-Ni-Be Alloy 显示文摘 | Subhash G Dowding R J Kecskes L J | 2002 | Mater Sci Eng A2002，334，： | 1 |
| 16 | Measuring dimensions of manufacturing flexibility显示文摘 | Lori L Koste Manoj K Malhotra Subhash Sharma | 2004 | Journal of Operations Management2004，22，2： | 1 |
| 17 | Effects of cell shape and cell wall thickness variations on the elastic properties of twodimensional cellular solids显示文摘 | Li K Gao X L Subhash G | 2005 | International Journal of Solids and Structure2005，42，56： | 1 |
| 18 | Synthesis,Optical Spectroscopy and Ultrafast Electron Dynamics of PbS Nanoparticles with Different Surface Capping显示文摘 | Amish a Patel Fanxin Wu Jin Z Zhang Claudia L Torres-Martinez Rajesh K Mehra Yi Yang Subhash H Risbud | 2000 | J Phys Chem B2000，104，11： | 1 |
| 19 | Effects of cell shape and cell wall thickness variations on the elastic properties of two-di- mensional cellular solids显示文摘 | Li K Gao X L Subhash G | 2005 | Int J Solids Struct2005，42，5： | 1 |
| 20 | Negative strain rate sensitivity and compositional dependence of fracture strength in Zr/Hf based bulk metallic glasses显示文摘 | Li H Subhash G Gao X L | | 0，，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员