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| 1 | 化学气体污染突发事件中的人群疏散:横断面调查显示文摘目的比较一个塑料工厂发生化学事故后躲藏和被疏散人群的健康结局。设计横断面调查。背景英格兰西南的市区。研究对象该地区1750位曾暴露于化学烟雾的居民,其中472人被疏散,剩下的1278人被建议躲藏在室内。主要结局测定不利于健康的症状数目。出现4个或以上症状者被确定为一个病例。主要的结果1096位居民(63%;299人被疏散,797人躲藏起来)为本分析提供了资料。被疏散人群的平均症状分值和病例的比例比躲藏人群的要高(疏散者:症状分值1.9,病例比例19.7%(n=59);躲藏者:症状分值1.0,病例比例9.5%(n=76),二者比较P<0.001)。在事故发生后两周末时二组间的差异明显变小。成为病例的两个主要可变更危险因子是疏散(比值比2.5,95%可信区间1.7~3.8)和在事故当天直接暴露于烟雾的时间超过2小时(比值比2.0,95%可信区间1.7~2.3)。住所距工厂的距离或是干预前(头6个小时)暴露的水平对于研究对象成为病例的作用不大。结论在此次化学事故中躲藏起来可能是优于疏散人群的保护措施。这与专家们普遍认为的观点一致。尽管本研究有一定的局限性,但它是基于一场真实的事件。疏散本身有一定的风险和资源上的限制,认识上的增加可能会有助于减少将来不必要的疏散。 | S Kinra G Lewendon R Nelder N Herriott R Mohan M Hort S Harrison V Murray 陈雷(译) | 2005 | 英国医学杂志中文版2005，8，5： | 3 |
| 2 | Ameliorative effects of standardized extract from Trigonella foenum-graecum L.seeds on painful peripheral neuropathy in rats显示文摘Objective:To evaluate the effects of the standardized extract of fenugreek(Trigonella foenumgraecum L.Family:Leguminasae) seed(IND01) in animal models of peripheral neuropathy. Methods:IND01 was prepared from fenugreek seeds and standardized by high performance liquid chromatography to a marker compound,trigonelline.The effects of daily oral administration of IND01(50,100 and 200 mg/kg) were studied in rats after partial sciatic nerve ligation(PSNL) and sciatic nerve crush injury(SNCI) during 30-days period.The measurements on thermal hyperalgesia(TH),motor function test(MFT) score and motor nerve conduction velocity (MNCV) were recorded.Results:IND01 offered sustained protection against TH and deranged MFT scores in both models from 7-day onwards.Fifteen days of daily oral administration of IND01 restored MNCV reduction in rats with SNCI but not with PSNL.Conclusions:IND01 was found to be effective in rat models of painful peripheral neuropathy. | Aashish S Morani Subhash L Bodhankar V Mohan Prasad A Thakurdesai | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，5： | 2 |
| 3 | Anti-oxidant and anti-inflammatory activity of leaf extracts and fractions of Mangifera indica显示文摘Objective:To evaluate the anti-oxidani and anti-inflammatory activity of leaf extracts and fractions of Mangifera indica in in vitro conditions.Methods:In vitro DPPH radical scavenging activity and lipoxygenase(LOX) inhibition assays were used to evaluate the anti-oxidant and anti-inflammatory activities respectively.Methanolic extract(MEMI),successive water extract (SWMI) and ethyl acetate fraction(EMEMI),n-butanol fraction(BMEMI) and water soluble fraction (WMEMI) of methanolic extract were evaluated along with respective reference standards. Results:In in ritro DPPH radical scavenging activity,the MEMI,EMEMI and BMEMI have offered significant antioxidant activity with IC50 values of 13.37.3.55 and 14.19μig/mL respectively.Gallic acid,a reference standard showed significant antioxidant activity with IC? value of 1.88 and found to be more potent compared to all the extracts and fractions.In m vitro LOX inhibition assay,the MEMI,EMEMI and BMEMI have showed significant inhibition of LOX enzyme activity with IC50 values of 96.71.63.21 and 107.44μg/mL respectively.While,reference drug Indometlhacin also offered significant inhibtion against LOX enzyme activity with IC50 of 57.75.Furthermore,MEMI was found to more potent than SWMI and among the fractions EMEMI was found to possess more potent antioxidant and anti-inflammatory activity.Conclusions:These findings suggest that the MEMI and F.MEMT possess potent anti-oxidani and anti-inflammatory activities in in vitro conditions. | Mohan CG Deepak M Viswanatha GL Savinay G Hanumantharaju V Rajendra CE Praveen D Halemani | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，4： | 2 |
| 4 | Treatment of simulated Reactive Yellow 22 (Azo) dye effluents using Spirogyra species 显示文摘 | Mohan S V Rao N C Prasad K K J | 2002 | Waste Management2002，22，6： | 1 |
| 5 | Friction characteristies of stir-cast Al-Pb alloys 显示文摘 | Agarwala V Ray S | 1990 | Wear1990，83，： | 1 |
| 6 | Efficacy and safety of sitagliptin in the treatment of patients with type 2 diabetes in China,India,and Korea显示文摘 | Mohan V Yang W Son H Y | 2009 | Diabetes Res Clin Pract2009，83，1： | 1 |
| 7 | Drug induced diabetes mellitus显示文摘 | Mohan LR Mohan V | 1997 | J Assoc Physicians India1997，45，11： | 1 |
| 8 | Influence of single-wall carbon nanotube addition on the microstructural and tensile properties of Sn-Pb solder alloy显示文摘 | Kumar K Mohan Kripesh V | 2008 | J Alloys Compd2008，455，： | 1 |
| 9 | A modified method for drought identification显示文摘 | Mohan S Rangacharya N C V | 1991 | Hydrological Sciences Journal1991，36，1： | 1 |
| 10 | CAD approach for simulation of generation machining and identification of contact lines显示文摘 | Mohan L V Shunmugam M S | 2004 | International Journal of Machine Tools & Manufacture2004，44，78： | 1 |
| 11 | Studies on distribution and fractionation of heavy metals in Gomti river sediments-a tributary of the Ganges, india显示文摘 | SINGH K P MOHAN D SINGH V K | 2005 | Journal of Hydrology2005，312，： | 1 |
| 12 | The added value of multislice SPECT/CT in patients with equivocal bony metastasis from carcinoma of the prostate显示文摘 | Helyar V Mohan H K Barwick T | 2010 | European Journal of Nuclear Medicine and Molecular Imaging2010，37，4： | 1 |
| 13 | Pathogenesis of cholangitis in obstructive jaundice-revisited显示文摘 | Navaneethan U Jayanthi V Mohan P | 2011 | Minerva Gastroenterol Dietol2011，57，1： | 1 |
| 14 | Oxidative DNA damage and augmentation of poly (ADP-ribose) polymerase/nuclear factor-kappa B signaling in patients with type 2 diabetes and microangiopathy 显示文摘 | Adaikalakoteswari A Rema M Mohan V | 2007 | Int J Biochem Cell Biol2007，39，9： | 1 |
| 15 | Financial benefits from JIT Adoption:Effects of Customer Concentration and Cost Structure显示文摘 | RAMJI B THOMAS J L MOHAN V | 1996 | Accounting Review1996，71，2： | 1 |
| 16 | Trivalent chromium removal from wastewater using low cost activated carbon derived from agricultural waste material and activated carbon fabric cloth显示文摘 | Mohan D Singh K P Singh V K | 2006 | Hazard Mater2006，135，： | 1 |
| 17 | Biofilm vaccine of Aeromonas hydrophila-standardization of dose and duration for oral vaccination of carps 显示文摘 | Azad I S Shanker K M Mohan C V | 1999 | Fish & Shellfish Immunology1999，9，： | 1 |
| 18 | On a Pure Finite-Element-Based Methodology for Resin Transfer Mold Filling Simulation显示文摘 | Mohan R V Ngo N D Tamma K K | 1999 | Polymer Engineering and Science1999，39，1： | 1 |
| 19 | Efficacy and safetyof sitagliptin in the treatment of patients with type 2 diabetes in China,India,and Korea 显示文摘 | MOHAN V YANG W SON H Y | 2009 | Diabetes Res ClinPract2009，，： | 1 |
| 20 | The genetic predisposition to fibrocalculous pancreatic diabetes显示文摘 | Kambo PK Hitman GA Mohan V | 1989 | Diabetologia1989，32，： | 1 |
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