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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Clinical pharmacology issues relevant to the dosing and toxicity of chemotherapy drugs in the elderly 显示文摘 | Tarun W Stuart M L | 2005 | Oncologist2005，10，8： | 1 |
| 3 | Rival penalized competitive learning (RPCL) : a topology-determining algorithm for analyzing gene expression data 显示文摘 | NAIR T M ZHENG C L FINK J L STUART R O GRIBSKOV M | 2003 | Computational Biology and Chemistry2003，27，6： | 1 |
| 4 | MCMC methods for functions:modifying old algorithms to make them faster显示文摘 | COTTER S L ROBERTS G O STUART A M | 2013 | Statistical Science2013，28，3： | 1 |
| 5 | A coprologicalsurvey of parasites of wild mantled howling monkeys,Alouatta palliatapalliate显示文摘 | STUART M D GREENSPAN L L GLANDER K E | 1990 | Journal of Wildlife Diseases1990，26，： | 1 |
| 6 | Zebra mussel invasion in a large, turbid river: Phytoplankton response to increased grazing 显示文摘 | Caraco N F Cole J J Raymond P A Strayer D L Pace M L Findlay Stuart E G Fischer D T | 1997 | Ecology1997，78，2： | 1 |
| 7 | Prognostic Factors in Acute Pancreatitis显示文摘 | STUART L TRIESTER M D KRIS V | 2002 | J Clin Gastroenterol2002，34，2： | 1 |
| 8 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 9 | Effects of carbon additions on the high temperature mechanical properties of molybdenum disilicide 显示文摘 | STUART A M JOHN J L ARTHUR H H | 1992 | Mater Sci Eng1992，155，7： | 1 |
| 10 | Varietal and envi- ronmental variations in ( 1 - 3,1 - 4) - 13 - gjucan lev- els and ( 1 - 3,1 - 4 ) - 13 - glucanase potential in bar- ley: relationships tomalting quality 显示文摘 | STUART I M LOI L FINCHER G B | 1988 | Journal of Cere- al Science1988，7，： | 1 |
| 11 | Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes 显示文摘 | GAVI S STUART L M KELLY P | 2007 | J Clin Endocrinol Metab2007，92，： | 1 |
| 12 | Structure and function of declarative and nondeclarative memory systems 显示文摘 | SQUIRE L R STUART M Z | 1996 | Pro- ceedings of National Academy Sciences1996，93，： | 1 |
| 13 | Multiple envi ronmental controls on phytoplankton growth strategies determine adaptive responses of the N : P ratio 显示文摘 | Stuart J D James R C Timothy M L | 2014 | E cology Letters2014，17，4： | 1 |
| 14 | Lncidence and specificity of interference in two - site immunoassays 显示文摘 | BOSCATO L M STUART M C | 1986 | Clin chem1986，32，： | 1 |
| 15 | Inhibitory effects of ap- optotic cel lingestion upon endotoxin driven myeloid dendritic cell maturation 显示文摘 | Stuart L M Lucas M Simpson C | 2002 | J Imnmnol2002，168，4： | 1 |
| 16 | Retinol -Binding Protein-4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes显示文摘 | GAVI S STUART L M KELLY P | 2007 | J Clin Endocrinol Metab2007，92，5： | 1 |
| 17 | One-year outcomes of panretinal photocoagulation in proliferative diabetic retinopathy显示文摘 | Richard S Kaiser Maureen G Maguire Juan E Grunwald Douglas Lieb Binoy Jani Alexander J Brucker Albert M Maguire Allen C Ho Stuart L Fine | 2000 | American Journal of Ophthalmology2000，，2： | 1 |
| 18 | Epithelioid sarcoma-like(pseudomyogenic)hemangioendothelioma, clinically mimicking dermatofibroma, diagnosed by skin biopsy in a 30-year-old man 显示文摘 | Stuart L N Gardner J M Lauer S R | 2013 | J Cutan Pathol2013，40，10： | 1 |
| 19 | Orf virus IL 10 accelerates wound healing while limiting inflammation and scarring显示文摘 | Wise L M Stuart G S Real N C | 2014 | Wound Repair Regen2014，22，3： | 1 |
| 20 | Geomorphic development of the escarpment of the Eritrean margin, southern Red Sea from combined apatite fission-track and (U-Th)/He thermochronometry 显示文摘 | Balestrieria M L Stuart F M Persano C Abbate E Bigazzi G | 2005 | Earth and Planetary Science Letters2005，231，12： | 1 |
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