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| 1 | Hepatic encephalopathy before and neurological complications after liver transplantation have no impact on the employment status 1 year after transplantation显示文摘AIM To investigate the impact of hepatic encephalopathybefore orthotopic liver transplantation(OLT) and neurological complications after OLT on employment after OLT.METHODS One hundred and fourteen patients with chronic liver disease aged 18-60 years underwent neurological examination to identify neurological complications, neuropsychological tests comprising the PSE-SyndromeTest yielding the psychometric hepatic encephalopathy score, the critical flicker frequency and the Repeatable Battery for the Assessment of Neuropsychological Status(RBANS), completed a questionnaire concerning their occupation and filled in the short form 36(SF-36) to assess health-related quality of life before OLT and 12 mo after OLT, if possible. Sixty-eight(59.6%) patients were recruited before OLT, while on the waiting list for OLT at Hannover Medical School [age: 48.7 ± 10.2 years, 45(66.2%) male], and 46(40.4%) patients were included directly after OLT. RESULTS Before OLT 43.0% of the patients were employed. The patients not employed before OLT were more often non-academics(employed: Academic/non-academic 16(34.0%)/31 vs not employed 10(17.6%)/52, P = 0.04), had more frequently a history of hepatic encephalopathy(HE)(yes/no; employed 15(30.6%)/34 vs not employed 32(49.2%)/33, P = 0.05) and achieved worse results in psychometric tests(RBANS sum score mean ± SD employed 472.1 ± 44.5 vs not employed 443.1 ± 56.7, P = 0.04) than those employed. Ten patients(18.2%), who were not employed before OLT, resumed work afterwards. The patients employed after OLT were younger [age median(range, min-max) employed 47(42, 18-60) vs not employed 50(31, 29-60), P = 0.01], achieved better results in the psychometric tests(RBANS sum score mean ± SD employed 490.7 ± 48.2 vs not employed 461.0 ± 54.5, P = 0.02) and had a higher health-related quality of life(SF 36 sum score mean ± SD employed 627.0 ± 138.1 vs not employed 433.7 ± 160.8; P < 0.001) compared to patients not employed after OLT. Employment before OLT(P < 0.001), age(P < 0.01) and SF-36 sum score 12 mo after OLT(P < 0.01) but not HE before OLT or neurological complications after OLT were independent predictors of the employment status after OLT.CONCLUSION HE before and neurological complications after OLT have no impact on the employment status 12 mo after OLT. Instead younger age and employment before OLT predict employment one year after OLT. | Henning Pflugrad Anita B Tryc Annemarie Goldbecker Christian P Strassburg Hannelore Barg-Hock Jürgen Klempnauer Karin Weissenborn | 2017 | World Journal of Hepatology2017，9，10： | 3 |
| 2 | In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor显示文摘 | Perzborn E Strassburger J Wilmen A | 2005 | J Thromb Haemost2005，3，3： | 1 |
| 3 | Conservation of an alpha 2 domain within the telenseanworld, MHC class I from therainbow trout Oncorhynchus mykiss 显示文摘 | Hansen J D Strassburger P D Pasquier L | 1996 | Dev Comp lmmunol1996，20，： | 1 |
| 4 | Prediction of survival after liver transplantation by pre-transplant parameters显示文摘 | Tobias J. Weismüller Jana Prokein Thomas Becker Hannelore Barg-Hock Jürgen Klempnauer Michael P. Manns Christian P. Strassburg | 2008 | Scandinavian Journal of Gastroenterology2008，，6： | 1 |
| 5 | In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939-an oral, direct factor Xa inhibitor 显示文摘 | Perzborn E Strassburger J Wilmen A | 2005 | J Thromb Haemost2005，3，3： | 1 |
| 6 | The need for future surgical low rectal cancer studies显示文摘 | Strassburg J Moran B J | 2006 | Colorectal Dis2006，8，113： | 1 |
| 7 | The need forfuture surgical low rectal cancer studies 显示文摘 | Daniels IR Strassburg J Moran BJ | 2006 | Colorectal Dis2006，8，3： | 1 |
| 8 | Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype显示文摘 | Strassburg S Richardson S M Freemont A J | 2010 | Regen Med2010，5，5： | 1 |
| 9 | Co- culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype 显示文摘 | Strassburg S Richardson SM Freemont A J | 2010 | Regen Med2010，5，5： | 1 |
| 10 | In vitro and in vivo studies of the novel antithrombotic agent BAY 597939-an oral, direct factor Xa inhibitor显示文摘 | PERZBORN E STRASSBURGER J WILMEN A | 2005 | J Thromb Haemost2005，3，3： | 1 |
| 11 | In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939 an oral, direct factor X a inhibitor 显示文摘 | Perzborn E Strassburger J Wilmen A | 2005 | J Thromb Haemost2005，3，3： | 1 |
| 12 | Indications for and Outcomes After Combined Lung and Liver Transplantation: A Single-Center Experience on 13 Consecutive Cases显示文摘 | Gerrit Grannas Michael Neipp Marius M. Hoeper Jens Gottlieb Rainer Lück Thomas Becker Andre Simon Christian P. Strassburg Michael P. Manns Tobias Welte Axel Haverich Jürgen Klempnauer Bj?rn Nashan Martin Strueber | 2008 | Transplantation2008，，4： | 1 |
| 13 | Portopulmonary hypertension and hepatopulmonary syndrome显示文摘 | Marius M Hoeper Michael J Krowka Christian P Strassburg | 2004 | The Lancet . 2004 (9419)2004，，9419： | 1 |
| 14 | In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939- an oral , direct factor Xa inhibitor显示文摘 | PERZBORN E STRASSBURGER J WILMEN A | 2005 | J Thromb Haemost2005，3，3： | 1 |
| 15 | Towards in situ tissue repair: human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2显示文摘 | RINGE J STRASSBURG S NEUMANN K | 2007 | J Cell Biochern2007，101，1： | 1 |
| 16 | The growth and optical properties of large, high-quality A1N single crystals显示文摘 | Strassburg M Senawiratne J Dietz N | 2004 | J Appl Phys2004，96，： | 1 |
| 17 | Portopulmonary hypertension and hepatopulmonary syndrome显示文摘 | Marius M Hoeper Michael J Krowka Christian P Strassburg | 2004 | The Lancet2004，，9419： | 1 |
| 18 | Description of an ectothermic TCR coreceptor, CD8, in rainbow trout 显示文摘 | Hansen J D Strassburger P | 2000 | Immunology2000，164，： | 1 |
| 19 | Transient autoimmune hepatitis induced by a thymoma显示文摘 | Aigner E Strassburg CP Strasser M Pohla-Gubo G Dietze O Hutter J | | 0，，： | 1 |
| 20 | Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype显示文摘 | STRASSBURG S RICHARDSON S M FREEMONT A J | 2010 | Regen Med2010，5，5： | 1 |
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