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    题名 作者 年代 出处 被引量
1肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) 2013中华胃肠外科杂志2013,16,7:70
2不同沉积环境及成熟度干酪根的碳氢同位素地球化学特征显示文摘干酪根的碳同位素组成与源岩类型有无相关性存在不同认识,此次研究表明,在陆相沉积条件下,腐泥型干酪根相对富集轻碳同位素^(12)C(δ^(13)C一般小于-28‰),腐殖型干酪根相对富集重碳同位素^(13)C(δ^(13)C一般大于-26‰)。热模拟实验表明,热演化过程对干酪根碳同位素不产生明显影响,但其H/C原子比随热演化程度增高而减小。已有资料对干酪根氢同位素研究较少,本文研究表明,干酪根的氢同位素组成主要与沉积介质的盐度有关。笔作者将干酪根氢同位素组成δD=-130‰作为源岩沉积介质为淡水和咸水一半咸水的界限,前者小于-130‰,后者大小-130‰。王万春 徐永昌 Manfred Schidlowski Eckhard Faber Wolfgang Stahl 1997沉积学报1997,15,A12:37
3Signaling transduction pathways involved in basophil adhesion and histamine release显示文摘Background Little is known about basophil with respect to the different signaling transduction pathways involved in spontaneous, cytokine or anti-IgE induced adhesion and how this compares to IgE-dependent and IgE-independent mediator secretion. The purpose of the present study was to investigate the roles of β1 andβ2 integrins in basophil adhesion as well as hosphatidylinositol 3-kinase (PI3K), src-kinases and extracellular signal regulated kinase (ERK)1/2 in basophil adhesion and histamine release (HR). Methods Basophils (purity of 10%-50%) were preincubated with anti-CD29 or anti-CD18 blocking antibodies before used for adhesion study. Basophils were preincubated with the pharmacological inhibitors wortmannin, PP1, PD98059 before used for adhesion and HR study. Cell adherence to bovine serum albumin (BSA) or fibronectin (Fn) was monitored using cell associated histamine as a basophil marker and the histamine was measured by the glass fiber assay. Results Basophil spontaneous adhesion to Fn was inhibited by anti-CD29. Interleukin (IL)-3, granulocyte/macrophage colony stimulating factor (GM-CSF) induced adhesion to BSA was inhibited by anti-CD18. Wortmannin at 1 μmol/L and PP1 at 20 μmol/L strongly interfered with, whereas PD98059 at 50 μmol/L weakly inhibited basophil spontaneous adhesion to Fn. One μmol/L wortmannin strongly inhibited IL-3, IL-5, GM-CSF and anti-IgE induced adhesion to BSA. PP1 at 20 μmol/L partly inhibited anti-IgE induced adhesion. Fifty μmol/L PD98059 marginally inhibited IL-5, weakly inhibited anti-IgE, partly inhibited GM-CSF induced adhesion. Wortmannin, PP1 and PD98059 inhibited anti-IgE (1:100 or 1:1000) induced basophil HR in a dose dependent manner. They inhibited calcium ionophore A23187 (10 μmol/L, 5 μmol/L) induced basophil HR in a dose dependent manner, but to different extend with PP1 being the most efficient. Conclusions Basophil spontaneous adhesion to Fn is mediated by β1-integrins whereas cytokine induced adhesion to BSA is mediated by β2-integrins. PI3K, src-kinases and ERK1/2 play distinct signaling roles in basophil adhesion and HR. PI3K is the key player whileERK1/2 is the weakest participant.SHA Quan Lars K. Poulsen Jens Gerwien NielsФdum Per Stahl Skov 2006Chinese Medical Journal2006,,2:8
4Use of models in large-area forest surveys: comparing model-assisted, model-based and hybrid estimation显示文摘This paper focuses on the use of models for increasing the precision of estimators in large-area forest surveys.It is motivated by the increasing availability of remotely sensed data,which facilitates the development of models predicting the variables of interest in forest surveys.We present,review and compare three different estimation frameworks where models play a core role:model-assisted,model-based,and hybrid estimation.The first two are well known,whereas the third has only recently been introduced in forest surveys.Hybrid inference mixes designbased and model-based inference,since it relies on a probability sample of auxiliary data and a model predicting the target variable from the auxiliary data.We review studies on large-area forest surveys based on model-assisted,modelbased,and hybrid estimation,and discuss advantages and disadvantages of the approaches.We conclude that no general recommendations can be made about whether model-assisted,model-based,or hybrid estimation should be preferred.The choice depends on the objective of the survey and the possibilities to acquire appropriate field and remotely sensed data.We also conclude that modelling approaches can only be successfully applied for estimating target variables such as growing stock volume or biomass,which are adequately related to commonly available remotely sensed data,and thus purely field based surveys remain important for several important forest parameters.Goran Stahl Svetlana Saarela Sebastian Schnell Soren Holm Johannes Breidenbach Sean P. Healey Paul L. Patterson Steen Magnussen Erik Naesset Ronald E. McRoberts Timothy G. Gregoire 2016Forest Ecosystems2016,3,2:7
5镍基合金Inconel718可切削加工性的试验研究显示文摘Inconel718是一种高强度耐热镍基合金,具有优良的高温强度、高温硬度和耐蚀性,在高温条件下能长期工作,已被广泛地应用于宇航工业、航空工业的涡轮发动机和相关零件的制造。分析Inconel718的机械性能、微观组织结构及其对切削加工性能的影响并进行了相关的试验验证,在试验数据的基础上,研究Inconel718中含碳量对切削过程中刀具磨损的影响。试验结果表明,Inconel718中含碳量在刀具后刀面磨损中起着非常重要的作用,Inconel718合金中含碳量越高,合金中所含的细微硬质夹杂物也越多,在切削过程中使刀具产生严重的后刀面磨粒磨损,从而降低材料的切削加工性。徐林红 江征风 Jan-Eric Stahl 2010现代制造工程2010,,2:7
6模腔压力曲线必须正确显示文摘模腔压力曲线是衡量塑料制品质量高低的综合指标,对塑料制品质量有着决定性的影响。阅读本文,可给读者加深了解模腔压力技术的实用性,了解欧洲著名汽车电子设备供应商是如何利用模腔压力技术,进行分析和优化注塑工艺,提高注塑生产的稳定性,进而提高制品质量。同时发现一个有趣的现象,无论注塑机性能好坏,均能生产出合格的制品,但前提条件是模腔压力曲线恒定相同。Jürgen Stahl Frank Koch 郑荣成(翻译) 2007国外塑料2007,25,7:4
7Microsurgical epididymal sperm aspiration: indications, techniques and outcomes显示文摘Microsurgical epididymal 精子渴望(方山) 从被选择并且取样了使用一台操作显微镜提供的高力量的光放大的 epididymis 的最佳的区域指包含精子的液体的检索。检索精子随后被使用让 intracytoplasmic 精子注射(ICSI ) 导致授精和怀孕。方山被是为在有给它复杂并发症的优秀精子,优秀报导授精和怀孕率,和低风险的高收益的妨碍的精子缺乏的人的精子检索的标准答案技术的许多专家考虑。然而,方山必须在一个操作房间里被执行,要求 microsurgical 技巧并且为用 ICSI 的复制仅仅是有用的。此处我们在场为方山,过程的技术表演和被报导了的结果的候选人病人的评估的概述。Aaron M Bernie Ranjith Ramasamy Doron S Stember Peter J Stahl 2013Asian Journal of Andrology2013,15,1:4
8Multipurpose use of the ‘bear claw’ (over‐the‐scope‐clip system) to treat endoluminal gastrointestinal disorders显示文摘Klaus M?nkemüller Shajan Peter Jay Toshniwal Daniel Popa Marzena Zabielski Richard D. Stahl Jayapal Ramesh C. Mel Wilcox 2014Digestive Endoscopy2014,,3:4
9母乳低聚糖的检测方法研究进展显示文摘母乳低聚糖(HMOS)在母乳中的含量仅次于乳糖和脂肪,其生理功能受到越来越多的重视。在对母乳低聚糖的研究中,关键问题之一是灵敏和可定量的检测方法。由于母乳低聚糖属于复杂的混合物,结构多样,且没有内在的发色团,使得对其进行结构分辨和定量检测都存在不小的难度。本文拟对母乳低聚糖检测方法的研究进展进行综述。朱婧 王鑫 向雪松 Stahl Bernd 王红伟 杨月欣 2016中国食品卫生杂志2016,28,3:4
10Spatial H202 Signaling Specificity: H202 from Chloroplasts and Peroxisomes Modulates the Plant Transcriptome Differentially显示文摘Nasser Sewelam Nils Jaspert Katrien Van Der Kelen Vanesa B. Tognetti Jessica Schmitz Henning Frerigmann Elia Stahl Frank Van Breusegem Veronica G. Maurino 2014Molecular Plant2014,7,7:4
11A Highly Efficient Agrobacterium-Mediated Method for Transient Gene Expression and Functional Studies in Multiple Plant Species显示文摘Although the use of stable transformation technology has led to great insight into gene function,its application in high-throughput studies remains arduous.Agro-infiltration have been widely used in species such as Nicotiana benthamiana for the rapid detection of gene expression and protein interaction analysis,but this technique does not work efficiently in other plant species,including Arabidopsis thaliana.As an efficient high-throughput transient expression system is currently lacking in the model plant species A.thaliana,we developed a method that is characterized by high efficiency,reproducibility,and suitability for transient expression of a variety of functional proteins in A.thaliana and 7 other plant species,including Brassica oleracea,Capsella rubella,Thellungiella salsuginea,Thellungiella halophila,Solanum tuberosum,Capsicum annuum,and N.benthamiana.Efficiency of this method was independently verified in three independent research facilities,pointing to the robustness of this technique.Furthermore,in addition to demonstrating the utility of this technique in a range of species,we also present a case study employing this method to assess protein–protein interactions in the sucrose biosynthesis pathway in Arabidopsis.Youjun Zhang Moxian Chen Beata Siemiatkowska Mitchell Rey Toleco Yue Jing Vivien Strotmann Jianghua Zhang Yvonne Stahl Alisdair R.Fernie 2020Plant Communications2020,1,5:4
12生精障碍的疗法显示文摘与继发性睾丸衰竭相比,男性生精障碍的治疗目前大都收效甚微。从激素治疗,到补充相应营养成分(抗氧化作用),很多种疗法都被尝试过了。虽然有些研究表明某些疗法有一定的效果,但是没有任何一种疗法能够对所有患者都起效,同时又无法预测该疗法能够适用于哪类患者。先天生精障碍可能由许多不同的还未被证实的精子产生方面的缺陷引起的。深入理解这些缺陷,能够帮助我们寻求更有效的治疗方案,同时能够帮助我们筛选某种疗法的适用患者群。本文着眼于综述目前男性不育激素和抗氧化疗法的基本原理和成效,特别关注生精障碍的相关疗法。尽管目前辅助生殖技术已经大大取代了生精障碍的传统医疗方法,但二者将继续齐头并进发挥作用,相互结合共同起效。Ranjith Ramasamy Peter J Stahl Peter N Schlegel 2012Asian Journal of Andrology2012,14,1:3
13Senescence-specific Alteration of Hydrogen Peroxide Levels in Arabidopsis thaliana and Oilseed Rape Spring Variety Brassica napus L.cv.Mozart显示文摘In order to analyze the signaling function of hydrogen peroxide (H2O2) production in senescence in more detail, we manipulated intracellular H2O2 levels in Arabidopsis thaliala (L.) Heynh by using the hydrogen-peroxide-sensitive part of the Escherichia coli transcription regulator OxyR, which was directed to the cytoplasm as well as into the peroxisomes. H2O2 levels were lowered and senescence was delayed in both transgenic lines, but OxyR was found to be more effective in the cytoplasm. To transfer this knowledge to crop plants, we analyzed oilseed rape plants Brassica napus L. cv. Mozart for H2O2 and its scavenging enzymes catalase (CAT) and ascorbate peroxidase (APX) during leaf and plant development. H2O2 levels were found to increase during bolting and flowering time, but no increase could be observed in the very late stages of senescence. With increasing H2O2 levels, CAT and APX activities declined, so it is likely that similar mechanisms are used in oilseed rape and Arabidopsis to control H2O2 levels. Under elevated CO2 conditions, oilseed rape senescence was accelerated and coincided with an earlier increase in H2O2 levels, indicating that H2O2 may be one of the signals to inducing senescence in a broader range of Brassicaceae.Stefan Bieker Lena Riester Mark Stahl Jürgen Franzaring Ulrike Zentgraf 2012Journal of Integrative Plant Biology2012,54,8:3
14FoxM1: At the crossroads of ageing and cancer显示文摘Jamila Laoukili Marie Stahl René H. Medema 2006BBA - Reviews on Cancer2006,,1:3
15Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury显示文摘Neel R. Sodha Richard T. Clements Jun Feng Yuhong Liu Cesario Bianchi Eszter M. Horvath Csaba Szabo Gregory L. Stahl Frank W. Sellke 2009The Journal of Thoracic and Cardiovascular Surgery2009,,:3
16Deletion or underexpression of the Y-chromosome genes CDY2 and HSFY is associated with maturation arrest in American men with nonobstructive azoospermia显示文摘成熟拘捕(麻省) 指导致临床的 nonobstructive 精子缺乏的细菌房间开发的失败。尽管人的 Y 染色体的 azoospermic 因素(AZF ) 区域清楚地在一些情况中被含有,因此,远,很,很少对哪个个人, Y 染色体基因为完全的男细菌房间开发是重要的被知道。我们寻求了在可以在在美国人口与麻省联系的 nonobstructive 精子缺乏的致病被含有的 Y 染色体上识别单个基因。有 Y 染色体 microdeletions 的 132 个人的遗传型显型分析被执行。与麻省联系的编码蛋白质的基因被一张遗传型显型地图的视觉分析识别。与麻省联系的基因在 Y 染色体的一个片断以内作为那些基因被选择完全或部分删除了,总是与可恢复的阴囊的精子的麻省和缺席被联系。每个识别基因抄本的表示然后与自发的麻省和妨碍的精子缺乏从病人的分开的队在阴囊的织物与量的 RT-PCR 被测量。为有麻省的协会的十候选人基因在重叠的 Y 染色体的一个 8.4-Mb 片断以内被识别 AZFb 区域。CDY2 和 HSFY 是唯一的识别了在表示的差别在麻省和妨碍的精子缺乏队之间为被观察的基因。有妨碍的精子缺乏的人有 12 褶层 CDY2 抄本的更高相对的表示(1.33 ± 0.40 对 0.11 ± 0.04;P=0.0003 ) 并且 16 褶层 HSFY 抄本的更高的表示(0.78 ± 0.32 对 0.05 ± 0.02;P=0.0005 ) 与有麻省的人相比。CDY2 和 HSFY 也仅仅是在有 Sertoli 房间的病人的 underexpressed 症候群。这些数据显示 CDY2 和 HSFY 位于为精子成熟是重要的,并且是在与麻省从人导出的阴囊的织物的 underexpressed 的 Y 染色体的一个片断以内。这些观察建议在 CDY2 或 HSFY 表示的缺陷能在麻省的致病被含有。Peter J Stahl Anna N Mielnik Christopher E Barbieri Peter N Schlegel Darius A Paduch 2012Asian Journal of Andrology2012,14,5:3
17The Interaction of the Arabidopsis Response Regulator ARR18 with bZIP63 Mediates the Regulation of PROLINE DEHYDROGENASE Expression显示文摘作为第一并且脯氨酸降级的限制率的酶,脯氨酸 DEHYDROGENASE1 (PDH1 ) 紧在植物压力回答期间被调整,包括在 hypoosmolarity 下面的正式就职和在 waterdeficit 下面的压抑。植物受体 histidine kinases AHK,在 Arabidopsis thaliana 的二部件的系统(TCS ) 的元素,被建议由调整不同压力应答的基因在水压力回答工作。然而,有关 AHK 可得到的小 informationis 调停 phosphorelay 的下游的发信号。这里,我们证明 Arabidopsis type-B 反应管理者(ARR18 ) 当在 Arabidopsis 的一个积极渗透的压力反应管理者播种并且影响 PDH1 倡导者的活动, 18 工作,知道被 Cgroup bZIP 抄写因素控制。而且, ARR18 withbZIP63 的直接物理的相互作用被识别并且出现依赖于在 ARR18 receiverdomain 的保存 aspartate 残余的 phosphorylation。我们进一步证明 bZIP63 本身在渗透的应力之上作为种子萌芽的一个否定管理者工作。在原物的 Usingreporter 基因试金,我们证明那个 ARR18 相互作用否定地在 PDH1 倡导者上防碍 bZIP63 的 transcriptionalactivity。我们的调查结果作为基因 expressionin Arabidopsis 的对抗管理者提供新卓见进 ARR18 和 bZIP63 的功能。Manikandan Veerabagu Tobias Kirchler Kirstin Elgass Bettina Stadelhofer Mark Stahl Klaus Harter Virtudes Mira-Rodado Christina Chaban 2014Molecular Plant2014,7,10:3
18A All Digital Receiver Architecture for Bandwidth Efficient Transmission at High Data Rates显示文摘Ascheid G Oerder M Stahl J 1989IEEE Trans Comm1989,37,8:2
19Regulatory and Functional Aspects of Indolic Metabolism in Plant Systemic Acquired Resistance显示文摘导出色氨酸, indolic 代谢物在 Arabidopsis 天生的免疫拥有多样的功能到微生物引起的病原体感染。这里,我们在全身的获得的抵抗(SAR ) 由细菌的病原体 Pseudomonas syringae 触发了的 Arabidopsis 调查功能的角色和 indolic 新陈代谢的规章的特征。Indolic 新陈代谢广泛地在两 P 被激活。接种 syringae 、远,非接种的叶子。在接种地点, camalexin, indol-3-ylmethylamine (I3A ) ,和 indole-3-carboxylic,酸(集成通信适配器) 是主要积累混合物。Camalexin 累积被 MYB122,和细胞色素 P450 基因 CYP81F1 和 CYP81F2 断然影响。由对比,本地 I3A 生产由 PEN2- 依赖、独立的小径经由吲哚 glucosinolate 故障发生。而且,防卫荷尔蒙水杨酸酸的外长的申请在损坏它的先锋的情况下刺激 I3A 产生 indol-3-ylmethylglucosinolate (I3M ) ,和 SAR 管理者 pipecolic 酸为提高的 P 告知植物。indolic 新陈代谢的不同分支的导致 syringae 的激活。在 uninfected 全身的织物,新陈代谢的反应与 indolics I3A,集成通信适配器,和 indole-3-carbaldehyde (国际计算中心) 的提高的层次更特定、联系。全身的吲哚累积充分取决于功能的 CYP79B2/3, PEN2,和 MYB34/51/122,并且要求功能的 SAR 发信号。基因分析建议全身地提高的吲哚为 SAR 是非必需的并且联系水杨酸酸的全身的增加。然而,土壤成年然而并非水耕法地栽培的 cyp79b2/3 和 pen2 种,在 indolic 有缺点的两个第二等的新陈代谢,展出预先导致的免疫,它废除他们的内在的能力导致 SAR。Elia Stahl Patricia Bellwon Stefan Huber Klaus Schlaeppi Friederike Bernsdorff Armelle Vallat-Michel Felix Mauch Jurgen Zeier 2016Molecular Plant2016,9,5:2
20A family of fatty acid transporters conserved from mycobacterium to man显示文摘Hirsch D Stahl A Lodish H F 1998Proc Natl Acad Sci U S A1998,95,15:2
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