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| 1 | Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis显示文摘Nonalcoholic fatty liver disease(NAFLD) is a condition in which excess fat accumulates in the liver of a patient without a history of alcohol abuse.Nonalcoholic steatohepatitis(NASH),a severe form of NAFLD,can progress to liver cirrhosis and hepatocellular carcinoma.NAFLD is regarded as a hepatic manifestation of metabolic syndrome and incidence has been increasing worldwide in line with the increased prevalence of obesity,type 2 diabetes,and hyperlipemia.Animal models of NAFLD/NASH give crucial information,not only in elucidating pathogenesis of NAFLD/NASH but also in examining therapeutic effects of various agents.An ideal model of NAFLD/NASH should correctly reflect both hepatic histopathology and pathophysiology of human NAFLD/NASH.Animal models of NAFLD/NASH are divided into genetic,dietary,and combination models.In this paper,we review commonly used animal models of NAFLD/NASH referring to their advantages and disadvantages. | Yoshihisa Takahashi Yurie Soejima Toshio Fukusato | 2012 | World Journal of Gastroenterology2012，18，19： | 57 |
| 2 | Small-for-size syndrome in liver transplantation:Definition,pathophysiology and management显示文摘Background:Since the first success in an adult patient,living donor liver transplantation(LDLT)has become an universally used procedure.Small-for-size syndrome(SFSS)is a well-known complication after partial LT,especially in cases of adult-to-adult LDLT.The definition of SFSS slightly varies among transplant physicians.The use of a partial liver graft has risks of SFSS development.Persistent portal vein(PV)hypertension and PV hyper-perfusion after LT were identified as the main factors.Hence,various approaches were explored to modulate PV flow and decrease PV pressure in order to alleviate this syndrome.Herein,the definition,clinical symptoms,pathophysiology,basic research,as well as preventive and treatment strategies for SFSS are reviewed based on an extensive review of the literature and on our own experiences.Data sources:The articles were collected through PubMed using search terms“liver transplantation”,“living donor liver transplantation”,“living liver donation”,“partial graft”,“small-for-size graft”,“small-forsize syndrome”,“graft volume”,“remnant liver”,“standard liver volume”,“graft to recipient body weight ratio”,“sarcopenia”,“porcine”,“swine”,and“rat”.English publications published before March 31,2020 were included in this review.Results:Many transplant surgeons performed PV flow modulation,including portocaval shunt,splenic artery ligation and splenectomy.With these techniques,patient outcome has been improved even when using a'small'graft.Other factors,such as preoperative recipients’nutritional and skeletal muscle status,graft congestion,and donor factors,were also identified as risk factors which all have been addressed using various strategies.Conclusions:The surgical approach controlling PV flow and pressure could help to prevent SFSS especially in severely ill recipients.In the absence of efficacious medications to resolve SFSS,conservative treatments,including aggressive fluid balance correction for massive ascites,anti-microbiological therapy to prevent or control sepsis and intensive nutritional therapy,are all required if SFSS could not be prevented. | Yuichi Masuda Kazuki Yoshizawa Yasunari Ohno Atsuyoshi Mita Akira Shimizu Yuji Soejima | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，4： | 13 |
| 3 | Prospective trial of combined transcatheter arterial chemoembolization and three-dimensional conformal radiotherapy for portal vein tumor thrombus in patients with unresectable hepatocellular carcinoma显示文摘 | Kazunari Yamada Kenta Izaki Koji Sugimoto Hiroshi Mayahara Yoshitaka Morita Eisaku Yoden Shinichi Matsumoto Toshinori Soejima Kazuro Sugimura | 2003 | International Journal of Radiation Oncology, Biology, Physics2003，，1： | 3 |
| 4 | Predictors of Extrahepatic Recurrence After Curative Hepatectomy for Hepatocellular Carcinoma显示文摘 | Akinobu Taketomi Takeo Toshima Dai Kitagawa Takashi Motomura Kazuki Takeishi Yohei Mano Hiroto Kayashima Keishi Sugimachi Shinichi Aishima Yoichi Yamashita Toru Ikegami Tomonobu Gion Hideaki Uchiyama Yuji Soejima Takashi Maeda Ken Shirabe Yoshihiko Maehar | 2010 | Annals of Surgical Oncology2010，，10： | 2 |
| 5 | Rituximab, IVIG, and Plasma Exchange Without Graft Local Infusion Treatment: A New Protocol in ABO Incompatible Living Donor Liver Transplantation显示文摘 | Toru Ikegami Akinobu Taketomi Yuji Soejima Tomoharu Yoshizumi Hideaki Uchiyama Noboru Harada Tomohiro Iguchi Naotaka Hashimoto Yoshihiko Maehara | 2009 | Transplantation2009，，3： | 2 |
| 6 | One‐step venous reconstruction for a right lobe graft with multiple venous orifices in living donor liver transplantation显示文摘 | Yuji Soejima Naoyuki Ueda Takasuke Fukuhara Tomoharu Yoshizumi Toru Ikegami Yoichi Yamashita Keishi Sugimachi Akinobu Taketomi Yoshihiko Maehara | 2008 | Liver Transpl2008，，5： | 2 |
| 7 | Hepatocyte growth factor and transforming growth factor β1 contribute to regeneration of small-for-size liver graft immediately after transplantation显示文摘 | Mizuki Ninomiya Noboru Harada Satoko Shiotani Shoji Hiroshige Ryosuke Minagawa Yuji Soejima Taketoshi Suehiro Takashi Nishizaki Mitsuo Shimada Keizo Sugimachi | 2003 | Transplant International2003，，11： | 2 |
| 8 | Prognostic Factors Affecting Survival at Recurrence of Hepatocellular Carcinoma After Living-Donor Liver Transplantation: With Special Reference to Neutrophil/Lymphocyte Ratio显示文摘 | Norifumi Harimoto Ken Shirabe Hidekazu Nakagawara Takeo Toshima Yo-ichi Yamashita Toru Ikegami Tomoharu Yoshizumi Yuji Soejima Tetsuo Ikeda Yoshihiko Maehara | 2013 | Transplantation Journal2013，，11： | 2 |
| 9 | A Simple Hilar Dissection Technique Preserving Maximum Blood Supply to the Bile Duct in Living Donor Liver Transplantation显示文摘 | Yuji Soejima Takasuke Fukuhara Kazutoyo Morita Tomoharu Yoshizumi Toru Ikegami Yoichi Yamashita Keishi Sugimachi Akinobu Taketomi Yoshihiko Maehara | 2008 | Transplantation2008，，10： | 2 |
| 10 | Extended Indication for Living Donor Liver Transplantation in Patients With Hepatocellular Carcinoma显示文摘 | Yuji Soejima Akinobu Taketomi Tomoharu Yoshizumi Hideaki Uchiyama Shinich Aishima Takahiro Terashi Mitsuo Shimada Yoshihiko Maehara | 2007 | Transplantation2007，，7： | 2 |
| 11 | One-step reconstruction of the right inferior hepatic veins using auto-venous grafts in living donor liver transplantation显示文摘 | Toru Ikegami Ken Shirabe Shohei Yoshiya Yuji Soejima Tomoharu Yoshizumi Hideaki Uchiyama Takeo Toshima Takashi Motomura Yoshihiko Maehara | 2013 | Surgery Today2013，，7： | 2 |
| 12 | Simultaneous nitrogen and phosphorus removal using denitrifying phosphate-accumulating organisms in a sequencing batch reactor显示文摘 | Satoshi Tsuneda Takashi Ohno Koichi Soejima Akira Hirata | 2005 | Biochemical Engineering Journal2005，，3： | 2 |
| 13 | Bacterial Sepsis after Living Donor Liver Transplantation: The Impact of Early Enteral Nutrition显示文摘 | Toru Ikegami Ken Shirabe Shohei Yoshiya Tomoharu Yoshizumi Mizuki Ninomiya Hideaki Uchiyama Yuji Soejima Yoshihiko Maehara | 2012 | Journal of the American College of Surgeons2012，，3： | 2 |
| 14 | Simultaneous nitrogen and phosphorus removal using denitrifying phosphate-accumulating organisms in a sequencing batch reactor显示文摘 | Tsuneda S Ohno T Soejima K | 2006 | Biochem Eng J2006，27，3： | 1 |
| 15 | Effects of imidapril therapy on endogenous fibrinolysis in patients with recent myocardial infarction显示文摘 | Soejima H Ogawa H Yasue H | 1997 | Clin Cardiol1997，20，： | 1 |
| 16 | Effects of pulsed electromagnetic field (PEMF)stimulation on bone tissue like formation are dependent on the maturation stages of the osteoblasts 显示文摘 | Diniz P Shomura K Soejima K | 2002 | Bioelectromagnetics2002，23，5： | 1 |
| 17 | Serial change in von Will-ebrand Factor-cleaving Protease(ADAMTS13)and prognosis afteracute myocardial infraction显示文摘 | Sukawa M Kaikita K Soejima K | 2007 | Am J Cardiol2007，100，： | 1 |
| 18 | Desulfurization of Molten Steel by Flux Addition in RH Degaser显示文摘 | Soejima T Sato T Matsomoto H | 1985 | Trans Iron Steel Inst1985，，25： | 1 |
| 19 | Use of steatotic graft in living donor liver transplantation显示文摘 | Soejima Y Shimada M Suehiro T | 2003 | Transplantation2003，76，： | 1 |
| 20 | Epigenetic silencing of the MGMT gene in cancer显示文摘 | ZHAO W MUKAI T | 2005 | Bioehem Cell Biol2005，83，4： | 1 |
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