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| 1 | Precise nanomedicine for intelligent therapy of cancer显示文摘Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations. | Huabing Chen Zhanjun Gu Hongwei An Chunying Chen Jie Chen Ran Cui Siqin Chen Weihai Chen Xuesi Chen Xiaoyuan Chen Zhuo Chen Baoquan Ding Qian Dong Qin Fan Ting Fu Dayong Hou Qiao Jiang Hengte Ke Xiqun Jiang Gang Liu Suping Li Tianyu Li Zhuang Liu Guangjun Nie Muhammad Ovais Daiwen Pang Nasha Qiu Youqing Shen Huayu Tian Chao Wang Hao Wang Ziqi Wang Huaping Xu Jiang-Fei Xu Xiangliang Yang Shuang Zhu Xianchuang Zheng Xianzheng Zhang Yanbing Zhao Weihong Tan Xi Zhang Yuliang Zhao | 2018 | Science China Chemistry2018，61，12： | 19 |
| 2 | Derivation of hypermethylated pluripotent embryonic stem cells with high potency显示文摘天真的 hypomethylated 胚胎的 pluripotent 干细胞(转换字符) 离胚囊的 preimplantation epiblast 发展地最靠近,与潜力到贡献所有胚胎的纸巾和 germline,除了在妄想的胚胎的胚胎外的纸巾。由对比,类似于 postimplantation epiblast 的 epiblast 干细胞(EpiSCs ) 是相对更多的 methylated 和表演为 chimerism 的一个有限潜力。第一次,这里,我们在 pluripotent 房间以外发展地揭示先进 pluripotent 干细胞(ASC ) ,它是在内部房间团中,但是与更高的力量比 EpiSCs。因此,单个 ASC 在怪物很高效地作出贡献到胎儿, germline,蛋黄囊和胎盘的迷宫。因为他们是,发展地,更多进展了, ASC 不贡献 trophoblast。ASC 在与 Activin A 和基本成纤维细胞生长因素补充的化学上定义的媒介在二个步骤从胚囊被导出,在包含 ActA, BMP4, CHIR99021 和白血病的 ABCL 媒介由 culturing 列在后面禁止的因素。尤其是, ASC 与天真的 pluripotency 基因,以及 mesodermal 的表示展出不同 transcriptome 体的基因;Eomes,时代, Tdgf1, Evx1, hand1, Wnt5a 和不同重复元素。到 ASC 的确定的转换字符的变换也是可完成的。重要地, ASC 作为与 hypomethylated 相比展出稳定的 hypermethylated epigenome 和主要未经触动的印记胚囊和天真的转换字符的内部房间质量。ASC 的性质建议他们以在 pluripotency 的天真、告知的状态之间的一个中间的细胞的状态代表房间。 | Siqin Bao Walfred WC Tang Baojiang Wu Shinseog Kim Jingyun Li Lin Li Toshihiro Kobayashi Caroline Lee Yanglin Chen Mengyi Wei Shudong Li Sabine Dietmann Fuchou Tang Xihe Li | 2018 | Cell Research2018，28，1： | 4 |
| 3 | Genome-wide identification and cold stress-induced expression analysis of the CBF gene family in Liriodendron chinense显示文摘Cold-resistance pathways that operate in model plants such as Arabidopsis thaliana and Oryza sativa have been studied extensively.It has been found that CBF genes play an important role in plant cold resistance.Liriodendron chinense,a tree known for its graceful tree shape and widely spread in south China,has weak cold tolerance.However,little is known about its response to cold.To further study the function of L.chinense CBF gene family,we started by characterizing all members of this gene family in the L.chinense genome and their expression profiling.Phylogenetic analysis found that 14 CBF genes in L.chinense are more closely related to their homologues in woody plants and A.thaliana than those in O.sativa.Cis-acting elements and GO analysis showed that some LcCBF genes participated in the biological process of cold stress response.The transcriptomic and RT-qPCR data showed that most of LcCBF genes displayed an initially increasing and subsequently decreasing trend during cold stress course and the expression profile of each member was different.Some LcCBF genes exhibited a different abundance in callus,root,stem and leaf tissues.The structure and expression characteristics of LcCBF genes imply that they may have similar and different functions in response to cold stress conditions.The identification and analysis of LcCBF gene family have laid the foundation for future studies into L.chinense cold stress mechanisms and for the cultivation of cold-resistance cultivars. | Yuanlin Guan Siqin Liu Weihuang Wu Kaiyue Hong Rongxue Li Liming Zhu Yang Liu Ye Lu Jinhui Chen Liming Yang Jisen Shi | 2021 | Journal of Forestry Research2021，32，6： | 3 |
| 4 | Microbial diversity and functionally distinct groups in produced water from the Daqing Oilfield,China显示文摘The microbial community structure and functionally distinct groups in three kinds of produced water samples from the shallow,mesothermic and low-salinity Daqing oil reservoir were systematically evaluated using both culture-dependent and culture-independent methods.Sequence analysis of the 16S rRNA genes indicated that the bacterial library was dominated by Acinetobacter and Arcobacter and the archaeal community was dominated by Methanosaeta and Methanolinea.Two isolated methanogens were closely related with Methanothermobacter thermautotrophicus and Methanoculleus receptaculi.The fermentative bacteria were identified as Pseudomonas,Haloanaerobium,Alcalibacter,Arcobacter,and Pannonibacter.The predominant nitrate-reducing bacteria fell within the genus Pseudomonas.The dominant members of the cultured hydrocarbon-oxidizing bacteria were phylogenetically associated with Micrococcus,Pseudomonas,and Bacillus.Enrichments of biosurfactants and biopolymer producing groups mainly yielded Pseudomonas,Bacillus,and Acenitobacter-related members.The functional groups related to polymer degradation were also affiliated with Pseudomonas and Bacillus.Results from this study provide the fresh insight into the diversity of microbial communities in Daqing petroleum reservoirs.The vast pool of functional strains retrieved in this study was presumed to include the promising strains that could be applied in microbial-enhanced oil recovery in future. | Li Hui Ai Mingqiang Han Siqin Guo Yanling Li Nana Shi Rongjiu Zeng Xiangling Leng Shengbing Zhao Jinyi Liu Xiaobo Zhang Ying | 2012 | Petroleum Science2012，9，4： | 3 |
| 5 | Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors显示文摘Considering that photodynamic therapy(PDT)-induced oxygen consumption and microvascular damage could exacerbate hypoxia to drive more glycolysis and angiogenesis, a novel approach to potentiate PDT and overcome the resistances of hypoxia is avidly needed. Herein, morpholine-modified PEGylated bilirubin was proposed to co-deliver chlorin e6, a photosensitizer, and diclofenac(Dc). In acidic milieu, the presence of morpholine could enable the nanocarriers to selectively accumulate in tumor cells, while PDT-generated reactive oxidative species(ROS) resulted in the collapse of bilirubin nanoparticles and rapid release of Dc. Combining with Dc showed a higher rate of apoptosis over PDT alone and simultaneously triggered a domino effect, including blocking the activity and expression of lactate dehydrogenase A(LDHA), interfering with lactate secretion, suppressing the activation of various angiogenic factors and thus obviating hypoxia-induced resistance-glycolysis and angiogenesis. In addition, inhibition of hypoxia-inducible factor-1a(HIF-1a) by Dc alleviated hypoxia-induced resistance. This study offered a sequentially responsive platform to achieve sufficient tumor enrichment, on-demand drug release and superior anti-tumor outcomes in vitro and in vivo. | Yang Zhou Fan Tong Weilong Gu Siqin He Xiaotong Yang Jiamei Li Yue-Dong Gao Huile Gao | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 2 |
| 6 | Electrochemical properties of niobium and phosphate doped spherical Li-rich spinel LiMn2O4 synthesized by ion implantation method显示文摘Spherical Li-rich lithium manganese oxide(LMO) spinel material was synthesized by an ion implanted method assisted by polyalcohol doped with Niobium and Phosphate simultaneously.The material was characterized by scanning electron microscopy,X-ray diffraction and BET specific surface area analysis.The electrochemical performances were investigated with galvanostatic techniques and cyclic voltammetry.The synthesis process was investigated with TG/DSC.The results show that the lithium ion can be immersed into the pore of manganese dioxide at a low temperature with the ion implanted method.The prepared materials have a higher discharge capacity and better crystallization than those prepared by solid phase method.The doped Nb can improve the capacity of the Li-rich LMO spinel and reinforce the crystal growth along(111) and(400) planes.The crystal grains show circular and smooth morphology,which makes the specific surface area greatly decreased.Phosphate-doped LMO spinel exhibits good high-rate capacity and structure stability.The prepared Li_(1.09)Mn_(1.87)Nb_(0.031)O_(3.99)(PO_4)_(0.021)delivers a discharge capacity of 119mAhg^(-1) at 0.2C(1C=148mAg^(-1)) and 112.8 mAhg^(-1) at 10 C,the discharge capacity retention reaches 98% at 1 ℃ after 50 cycles at 25 ℃ and 94% at 55 ℃. | Wei Li Gao-Wa Siqin Zhi Zhu Lu Qi Wen-Huai Tian | 2017 | Chinese Chemical Letters2017，28，7： | 2 |
| 7 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 8 | Human mobility data in the COVID-19 pandemic:characteristics,applications,and challenges显示文摘The COVID-19 pandemic poses unprecedented challenges around the world.Many studies have applied mobility data to explore spatiotemporal trends over time,investigate associations with other variables,and predict or simulate the spread of COVID-19.Our objective was to provide a comprehensive overview of human mobility open data to guide researchers and policymakers in conducting data-driven evaluations and decision-making for the COVID-19 pandemic and other infectious disease outbreaks.We summarized the mobility data usage in COVID-19 studies by reviewing recent publications on COVID-19 and human mobility from a data-oriented perspective.We identified three major sources of mobility data:public transit systems,mobile operators,and mobile phone applications.Four approaches have been commonly used to estimate human mobility:public transit-based flow,social activity patterns,index-based mobility data,and social media-derived mobility data.We compared mobility datasets’characteristics by assessing data privacy,quality,space–time coverage,high-performance data storage and processing,and accessibility.We also present challenges and future directions of using mobility data.This review makes a pivotal contribution to understanding the use of and access to human mobility data in the COVID-19 pandemic and future disease outbreaks. | Tao Hu Siqin Wang Bing She Mengxi Zhang Xiao Huang Yunhe Cui Jacob Khuri Yaxin Hu Xiaokang Fu Xiaoyue Wang Peixiao Wang Xinyan Zhu Shuming Bao Wendy Guan Zhenlong Li | 2021 | International Journal of Digital Earth2021，14，9： | 1 |
| 9 | Erratum to t Over- expression of long non- coding RNA HOTAIR leads to chemoresistance by activating the Wnt/- catenin pathway in human ovarian cancer显示文摘 | Jing Li Siqin Yang Ning Su | 2015 | Tumor Biol''2015，36，： | 1 |
| 10 | Rheological properties of flaxseed meal and soybean protein isolate blend by extrusion显示文摘The rheological properties of flaxseed meal(FM)and Soybean Protein Isolate(SPI)extruded by the two-screw extruder under different processing conditions were investigated.Moisture,temperature,screw speed and SPI concentration were the four major factors for the extrusion process.The rheological properties of extruded products were calculated by steady state flow test,frequency sweep test and creep test.All the samples showed shear-thinning effect that is to say their apparent viscosities decreased with the increases of shear rate.The data fitted well to Power Law model.It was found that both the storage(G′)and loss modulus increased as the rise in the angular frequency(w),which also fitted well to Power Law model.The creep-recovery behavior of the samples fitted well to Burger’s model.In addition,the temperature had no significant effect on the creep recovery rate of the samples. | Li Siqin Wu Min Zhao Donglin Liu Yi Sun Yang Li Dong | 2017 | International Journal of Agricultural and Biological Engineering2017，10，4： | 1 |
| 11 | A GIS-based analytical framework for evaluating the effect of COVID-19 on the restaurant industry with big data显示文摘COVID-19 cripples the restaurant industry as a crucial socioeconomic sector that contributes immensely to the global economy.However,what the current literature less explored is to quantify the effect of COVID-19 on restaurant visitation and revenue at different spatial scales,as well as its relationship with the neighborhood character-istics of customers’origins.Based on the Point of Interest(POI)measures derived from SafeGraph data providing mobility records of 45 million cell phone users in the US,our study takes Lower Manhattan,New York City,as the pilot study,and aims to examine 1)the change of restaurant visitations and revenue in the period prior to and after the COVID-19 outbreak,2)the areas where restaurant customers live,and 3)the association between the neighborhood characteristics of these areas and lost customers.By doing so,we provide a geographic information system-based analytical frame-work integrating the big data mining,web crawling techniques,and spatial-economic modelling.Our analytical framework can be implemented to estimate the broader effect of COVID-19 on other industries and can be augmented in a financially monitoring manner in response to future pandemics or public emergencies. | Siqin Wang Ruomei Wang Xiao Huang Zhenlong Li Shuming Bao | 2023 | Big Earth Data2023，7，1： | 1 |
| 12 | Blastoids generated purely from embryonic stem cells both in mice and humans显示文摘Dear Editor,Embryonic stem cells(ESCs)and trophoblast stem cells(TSCs)are derived from blastocysts(Lu et al.,2001).Blastocyst-like structures(blastoids)are self-assembled structures formed by a combination of ESCs and TSCs(Rivron et al.,2018).To increase the success rate of blastoid formation and its similarity with the features of blastocysts,some reports showed that blastoid could also be derived from a combination of three cell lines,ESCs,TSCs,and extraembryonic endoderm cells(XENs),or novel type of stem cells(Sozen et al.,2018;Weatherbee et al.,2023:Wu et al.,2023;Zhang et al.,2023;Zhang et al.,2019). | Baojiang Wu Yanqiu Wang Jia Yan Mengya Liu Xihe Li Fuchou Tang Siqin Bao | 2024 | Science China(Life Sciences)2024，67，2： | 0 |
| 13 | A new species of Chresmodidae from Mid-Cretaceous amber discovered in Myanmar显示文摘The extinct new species,Chresmoda chikuni Zhang & Ge,sp. nov. is described from the Mid-Cretaceous amber from northern Myanmar. This amber insect exhibits a very peculiar combination of derived characters like strongly elongated,free coxa,non-clawed pretarsus. The type specimens are deposited in the Three Gorges Entomological Museum,Chongqing,China. | Weiwei Zhang Wanzhi Cai Wenzhu Li Xingke Yang Siqin Ge | 2017 | Zoological Systematics2017，42，2： | 0 |
| 14 | Corrosion and tribocorrosion resistance of MAO-based composite coating on AZ31 magnesium alloy显示文摘In this paper, a multi-functional composite coating with low friction coefficient, high wear resistance and excellent tribocorrosion resistance is fabricated on AZ31 Mg alloys by micro-arc oxidation and spray-coating methods. The microstructure, and composition of the coating are characterized by SEM, EDS, XRD, and FT-IR. Potentiodynamic polarization and EIS tests are conducted to evaluate the corrosion resistance of the composite coating. The tribocorrosion property is also studied using pin-on-disk tribometer in 3.5 wt.% Na Cl solution. It is found that the composite coating possesses better long-term corrosion resistance than the single MAO coating. The tribocorrosion tests prove that the composite coating exhibits much better wear and tribocorrosion resistance than the single MAO coating and can protect the substrate from corrosion under a sliding condition. | Siqin Liu Guihua Li Yuming Qi Zhenjun Peng Yinping Ye Jun Liang | 2022 | Journal of Magnesium and Alloys2022，10，12： | 0 |
| 15 | The gross α and β radioactivity levels of drinking water source in one oil industrial city in northeast China显示文摘Objective:To investigate the grossαandβradioactivity levels of drinking water source in the city,the largest oil field production base in northeast China,in order to ensure the safety of drinking water and public health.Methods:The water samples from three drinking water sources were collected and tested in the dry and wet season,respectively.The grossαradioactivity was measured by standard curve method,grossβwas measured by thin sample method.Results:Totally 184 samples were collected from the three sampling areas in dry and wet season respectively.The average values of grossαandβradioactivity levels in the drinking water source area were(0.24±0.09)and(0.30±0.17)Bq/L respectively.The average activity concentration of grossαand grossβin the dry season was(0.23±0.09)and(0.29±0.18)Bq/L,respectively.The grossαandβradioactivity levels gradually decreased from the intake to the end of the reservoir of drinking water source areas.Conclusions:The grossαandβradioactivity levels and distribution of drinking water source areas in this city were all lower than the drinking water limit issued by China and the reference level recommended by the World Health Organization.The radioactivity of water body of the drinking water source was within the normal background level. | Yan Shi Wa Gao Tuya Siqin Zhigang Li Jianwei Zhang Rongshu Guan Jinfeng Li Peilin Sun Hongtao Zhao | 2021 | Radiation Medicine and Protection2021，2，2： | 0 |
| 16 | Dual-responsive supramolecular photodynamic nanomedicine with activatable immunomodulation for enhanced antitumor therapy显示文摘A major challenge facing photodynamic therapy(PDT) is that the activity of the immuneinduced infiltrating CD8^(+)T cells is subject to the regulatory T lymphocytes(Tregs), leaving the tumor at risk of recurrence and metastasis after the initial ablation. To augment the antitumor response and reprogram the immunosuppressive tumor microenvironment(TME), a supramolecular photodynamic nanoparticle(DACss) is constructed by the host-guest interaction between demethylcantharidin-conjugated β-cyclodextrin(DMC-CD) and amantadine-terminated disulfide-conjugated FFVLGGGC peptide with chlorin e6 decoration(Ad-ss-pep-Ce6) to achieve intelligent delivery of photosensitizer and immunomodulator for breast cancer treatment. The acid-labile β-carboxamide bond of DMC-CD is hydrolyzed in response to the acidic TME, resulting in the localized release of DMC and subsequent inhibition of Tregs.The guest molecule Ad-ss-pep-Ce6 can be cleaved by a high level of intracellular GSH, reducing photosensitizer toxicity and increasing photosensitizer retention in the tumor. With a significant increase in the CTL/Treg ratio, the combination of Ce6-based PDT and DMC-mediated immunomodulation adequately achieved spatiotemporal regulation and remodeling of the TME, as well as improved primary tumor and in situ lung metastasis suppression with the aid of PD-1 antibody. | Siqin He Lulu Wang Dongxu Wu Fan Tong Huan Zhao Hanmei Li Tao Gong Huile Gao Yang Zhou | 2024 | Acta Pharmaceutica Sinica B2024，14，2： | 0 |
| 17 | Analysis of Turbulence on Cylinder with Additional Fairing with Free Surface显示文摘In this study,two dimensional unsteady flows of cylinder and cylinder with additional fairing close to a free surface were numerically investigated.The governing momentum equations were solved by using the Semi Implicit Method for Pressure Linked Equations(SIMPLE).The Volume of Fluid(VOF)method applied to simulate a free surface.Non-uniform grid structures were used in the simulation with denser grids near the cylinder.Under the conditions of Reynolds number 150624,271123,210874 and 331373,the cylinders were simulated with different depths of invasion.It was shown that the flow characteristics were influenced by submergence depth and Reynolds numbers.When the cylinder close to the free surface,the drag coefficient,lift coefficient and Strouhal numbers will increase due to the effect of free liquid surface on vortex shedding.With additional fairing,can effectively reduce the influence of the free surface on the drag coefficient.Fairing will reduce lift coefficient at high Reynolds numbers,but increase lift coefficient when Reynolds numbers are small.Fairing can effectively reduce Strouhal numbers,thus can well suppress the vortex induced vibration. | Siqin Chen Xiaomin Li | 2021 | Journal of Mechanical Engineering Research2021，4，1： | 0 |
| 18 | A replacement name for Chrysolina mikhailovi Lopatin, 2011(Coleoptera:Chrysomelidae:Chrysomelinae), primary junior homonym of Ch. mikhailovi Ge & Daccordi, 2011显示文摘A replacement name is provided for Chrysolina mikhailovi Lopatin, 2011, a primary junior homonym of Ch. mikhailovi Ge & Daccordi, 2011, namely Ch. yurimikhailovi nomen novum. Habitus and aedeagus of Ch. mikhailovi Ge & Daccordi, 2011, and aedeagus of Ch. yurimikhailovi nom. nov. are provided. | Xiaolong Wang Siqin Ge Shaoqin Li | 2020 | Zoological Systematics2020，45，1： | 0 |
| 19 | Biomaterial-induced macrophage polarization for bone regeneration显示文摘As the main target cells of immune regulation,macrophages play an important role in the bone regeneration process.Macrophages can be polarized into the M1 and M2 types under the stimulation of different factors.They have proinflammatory and anti-inflammatory effects,respectively,and play key roles in different stages of bone regeneration.The ratio of M1 to M2 macrophages can be regulated by immunomodulatory biomaterials to promote bone repair and regeneration.In this paper,we review the recent literature on the chemical,physical and biological properties of biomaterials and the regulation of macrophage polarization under the influence of other factors.We also cover new methods for preparing immunomodulatory biomaterials for bone regeneration.This paper will provide new design ideas for the development of biomaterials with immunological properties and will support the clinical translation of bone-related medical biomaterials. | Long Chen Zhicheng Yao Siqin Zhang Kuihan Tang Qiming Yang Yuanzheng Wang Bohan Li Yingjie Nie Xiaobin Tian Li Sun | 2023 | Chinese Chemical Letters2023，34，6： | 0 |
| 20 | Homojunction structure amorphous oxide thin film transistors with ultra-high mobility显示文摘Amorphous oxide semiconductors(AOS)have unique advantages in transparent and flexible thin film transistors(TFTs)applications,compared to low-temperature polycrystalline-Si(LTPS).However,intrinsic AOS TFTs are difficult to obtain field-effect mobility(μFE)higher than LTPS(100 cm^(2)/(V·s)).Here,we design ZnAlSnO(ZATO)homojunction structure TFTs to obtainμFE=113.8 cm^(2)/(V·s).The device demonstrates optimized comprehensive electrical properties with an off-current of about1.5×10^(-11)A,a threshold voltage of–1.71 V,and a subthreshold swing of 0.372 V/dec.There are two kinds of gradient coupled in the homojunction active layer,which are micro-crystallization and carrier suppressor concentration gradient distribution so that the device can reduce off-current and shift the threshold voltage positively while maintaining high field-effect mobility.Our research in the homojunction active layer points to a promising direction for obtaining excellent-performance AOS TFTs. | Rongkai Lu Siqin Li Jianguo Lu Bojing Lu Ruqi Yang Yangdan Lu Wenyi Shao Yi Zhao Liping Zhu Fei Zhuge Zhizhen Ye | 2023 | Journal of Semiconductors2023，44，5： | 0 |
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