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| 1 | The role of cationic conditioning compounds in reinforcement of the cuticula显示文摘 | Sigrid B R Kamath Y K Weigmann H D | 2003 | J Cosmet Sci2003，54，： | 1 |
| 2 | Toxicity of Diphenylamine and some of its Nitrated and Aminated Derivatives to the Luminescent Bacterium Vibrio fischeri显示文摘 | OLIVER D SIGRID J KARL H B | 1995 | Ecotoxicology and Environmental Safety1995，31，： | 1 |
| 3 | AngiotensinⅠconverting enzyme and chymase in cardiovascular tissues显示文摘 | Sigrid H Ovidiu B | 1996 | Kidney International1996，49，55： | 1 |
| 4 | Incorporation of an unnatural amino acid in the active site of porcine pancreatic phospholipase A2 Substitution of histidine by l,2,4-triazole-3-alanine yields an enzyme with high activity at acidic pH显示文摘 | Sigrid H W B Bert v d B Niek D | | 0，，04： | 1 |
| 5 | Introduction to species diversity of marine zooplankton显示文摘 | PETER H W SIGRID B S SHUHEI N | 2010 | Deep Sea Research Part II: Topical Studies in Oceanography2010，57，242526： | 1 |
| 6 | Quality of Life, Psychosocial Well-Being, and Sexual Satisfaction in Women with Polycystic Ovary Syndrome显示文摘 | Sigrid E Susanne H Daniela K | 2003 | J Clin Endocrinol Metab2003，88，12： | 1 |
| 7 | AngiotensinⅠconverting enzyme and chymase in cardiovascular tissues显示文摘 | Hikaru N Sigrid H Ovidiu B | 1996 | Kidney Int1996，49，55： | 1 |
| 8 | Outcome of combined penterating keratoplasty with vitreoretinal surgery for management of severe ocular injuries显示文摘 | Sigrid R Peter S Sigrid H | 2003 | Retina2003，23，1： | 1 |
| 9 | Long - term treatment of rats with FGF - 2 results in focal segmental glomerylosclerosis显示文摘 | Wilhelm K Brunhilde H Sigrid R | 1995 | Kid Int1995，48，6： | 1 |
| 10 | Simultaneous identification of differential gene expression and connectivity in inflammation,adipogenesis and cancer显示文摘 | REVERTER A INGHAM A SIGRID A LEHNERT TAN S H WANG Y H RATNAKUMAR A DALPYMPLE B P | 2006 | Bioioformatics2006，22，19： | 1 |
| 11 | Transient left ventricular apical ballooning in a community hospital in Germany显示文摘 | Klaus Hertting Korff Krause Tobias H?rle Sigrid Boczor Jacobus Reimers Karl-Heinz Kuck | 2005 | International Journal of Cardiology2005，，3： | 1 |
| 12 | Reaction Kinetics of Selected Micropollutants in Ozonation and Advanced Oxidation Processes显示文摘 | Jin X H Sigrid P Peter M H | 2012 | Water Research2012，46，19： | 1 |
| 13 | A method to screen obstructive sleep apnea using multi-variable non-intrusive measurements显示文摘 | Sigrid de S Uuantha R Craig H | 2011 | Physiolo-gical Measurement2011，32，4： | 1 |
| 14 | Tabu search algorithms for job-shop problems with a single transport robot 显示文摘 | Johann H Sigrid K | 2005 | European Journal of Operational Research2005，162，1： | 1 |
| 15 | Long-term treatment of rats with FGF-2 results in focal segmental glomerylosclerosis显示文摘 | Brunhilde H Sigrid R | 1995 | Kidney Int1995，48，6： | 1 |
| 16 | Diagnosis and management of ST elevation myocardial infarction; A review of the recent literature and practice guidelines显示文摘 | Sigrid A H Charles C | 2006 | The Mount Sinai Journal of Medicine2006，73，1： | 1 |
| 17 | AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor显示文摘 | Sigrid H Katrien P Erik D | 2005 | Biochem Pharmacol2005，70，5： | 1 |
| 18 | Integrated ecological assessment of Danish Baltic Sea coastal areas by means of phytoplankton and macro phytobenthos显示文摘 | Sigrid S Dorte K J Peter H | 2005 | Estuarine Coastal and Shelf Science2005，，63： | 1 |
| 19 | HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation显示文摘AIM:To investigate influence of human leukocyte antigen(HLA)and killer immunoglobuline-like receptor(KIR)genotypes on risks of acute rejection(AR)after liver transplantation(LTX).METHODS:In this retrospective study we included143 adult donor-recipient pairs with a minimum of 6mo follow-up after LTX for whom DNA was available from both donor and recipients.Clinical data,all early complications including episodes and severity of AR and graft/patient survival were registered.The diagnosis of AR was based on clinical,biochemical and histological criteria.All suspected episodes of AR were biopsy confirmed.Key classical HLA loci(HLA-A,HLA-B,HLA-C and HLA-DRB1)were genotyped using Sanger sequencing.16 KIR genes were genotyped using a novel real time PCR approach which allows for determination of the diploid copy number of each KIR gene.Immunohistochemical staining for T(CD3),B(CD20)and natural killer(NK)cells(CD56 and CD57)were performed on liver biopsies from 3 different patient groups[primary sclerosing cholangitis(PSC),primary biliary cirrhosis and non-autoimmune liver disease],10 in each group,with similar grade of AR.RESULTS:Fourty-four(31%)patients were transplanted on the basis of PSC,40%of them had AR vs 24%in the non-PSC group(P=0.04).No significant impact of donor-recipient matching for HLA and KIR genotypes was detected.In the overall recipient population an increased risk of AR was detected for HLA-B*08(P=0.002,OR=2.5;95%CI:1.4-4.6),HLA-C*07(P=0.001,OR=2.4;95%CI:1.4-4.0)and HLA-DRB1*03(P=0.03,OR=1.9;95%CI:1.0-3.3)and a decreased risk for HLA-DRB1*04(P=0.001,OR=0.2;95%CI:0.1-0.5).For HLA-B*08,HLA-C*07 and DRB1*04 the associations remained evident in a subgroup analysis of non-PSC recipients(P=0.04,P=0.003 and P=0.02,respectively).In PSC recipients corresponding P values were 0.002,0.17 and 0.01 for HLA-B*08,HLA-C*07and DRB1*04,respectively.A dosage effect of AR prevalence according to the PSC associated HLA alleles was also notable in the total recipient population.For HLA-B*08 the frequency of AR was 56%in HLA-B*08homozygous recipients,39%in heterozygous recipients and 21%in recipients lacking HLA-B*08(P=0.02).The same was observed for the HLA-C*07 allele with AR in 57%,27%and 18%in recipients being homozygous,heterozygous and lacking HLA-C*07 respectively(P=0.003).Immunohistochemical analysis showed similar infiltration of T,B and NK cells in biopsies with AR in all three groups.CONCLUSION:We found significant associations between the PSC-associated HLA-B*08,HLA-C*07,HLADRB1*03 and HLA-DRB1*04 alleles and risk of AR in liver transplant recipients. | Bjarte Fosby Sigrid Nss Johannes R Hov James Traherne Kirsten M Boberg John Trowsdale Aksel Foss Pl-Dag Line Andre Franke Espen Melum Helge Scott Tom H Karlsen | 2014 | World Journal of Gastroenterology2014，20，14： | 0 |
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