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| 1 | Ultrasound biomicroscopy in chronic ocular hypotony:its impact on diagnosis and management显示文摘 | Sigrid R Peter S Bert E Karl BS Gunter K | 2002 | Retina2002，22，5： | 1 |
| 2 | The role of cationic conditioning compounds in reinforcement of the cuticula显示文摘 | Sigrid B R Kamath Y K Weigmann H D | 2003 | J Cosmet Sci2003，54，： | 1 |
| 3 | Heat-activated liposomal MR contrast agent:Initial in vivo results in rabbit liver and kidney 显示文摘 | Nathan M Sigrid L Henrik R | 2004 | Radiulogy2004，230，： | 1 |
| 4 | Polycondensations of bisphenol-A with diphosgene or triphosgene in water-free organic solvents显示文摘 | Hans R Kricheldorf Sigrid Bohme Gert Schwarz | 2005 | Macromol Chem Phys2005，206，： | 1 |
| 5 | Life-Cycle Assessment of Residential Building in Three Different European Locations,Case Study显示文摘 | ROSSI B ANNE-FRANCOISE M SIGRID R | 2012 | Building and Environment2012，51，5： | 1 |
| 6 | Mild hyperthermia down-regulates receptor-dependent neutrophil function显示文摘 | Dieter F Sigrid W Gregor R | 2004 | Anesthesia analgesia2004，99，： | 1 |
| 7 | Modificationof poly(vinylidene fluoride)ultrafiltration mem-branes with poly(vinyl alcohol)for fouling control indrinking water treatment显示文摘 | Jennifer R D Sigrid P Peter M | 2009 | Water Research2009，43，18： | 1 |
| 8 | Microstructure and crystallographic orientation relationship in directionally solidified Mg-Mg17Al12-eutectic 显示文摘 | Sigrid G Nils R | 2000 | Materials Science and Engineering A2000，，289： | 1 |
| 9 | Outcome of combined penterating keratoplasty with vitreoretinal surgery for management of severe ocular injuries显示文摘 | Sigrid R Peter S Sigrid H | 2003 | Retina2003，23，1： | 1 |
| 10 | Hydrolytic polycondensation of bisphenol-A bischloroformate catalyzed by phase-transfer catalysts显示文摘 | Sigrid B(o)hme Gert Schwarz | 2003 | Macromolecular Chemistry and Physics2003，204，： | 1 |
| 11 | Polymers of carbonic acid,31 cyclic polycarbonates by hydrolytic polycondensation of bisphenol-A bischloroformate显示文摘 | Sigrid B(o)hme Gert Schwarz | 2002 | Macromolecular Rapio Communi-cations2002，23，： | 1 |
| 12 | Long - term treatment of rats with FGF - 2 results in focal segmental glomerylosclerosis显示文摘 | Wilhelm K Brunhilde H Sigrid R | 1995 | Kid Int1995，48，6： | 1 |
| 13 | Uitrasound biomicroscopy in chronic ocular hypotony:its impact on diagnosis and management显示文摘 | Sigrid R Peter S Bert E | 2002 | Retina2002，22，5： | 1 |
| 14 | A method to screen obstructive sleep apnea using multi-variable non-intrusive measurements显示文摘 | Sigrid de S Uuantha R Craig H | 2011 | Physiolo-gical Measurement2011，32，4： | 1 |
| 15 | Long-term treatment of rats with FGF-2 results in focal segmental glomerylosclerosis显示文摘 | Brunhilde H Sigrid R | 1995 | Kidney Int1995，48，6： | 1 |
| 16 | Hydrolytic polycondensation of bisphenol-a-bischloroformate catalyzed by phase-transfer catalysts显示文摘 | Hans R Kricheldorf Sigrid B hme Gert Schwarz | 2003 | Macromolecular chemistry and physics2003，204，： | 1 |
| 17 | Life-cycle assessment of residential building in three different European locations, case study显示文摘 | Rossi B Anne-Francoise M Sigrid R | 2012 | Building and Environment2012，51，5： | 1 |
| 18 | HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation显示文摘AIM:To investigate influence of human leukocyte antigen(HLA)and killer immunoglobuline-like receptor(KIR)genotypes on risks of acute rejection(AR)after liver transplantation(LTX).METHODS:In this retrospective study we included143 adult donor-recipient pairs with a minimum of 6mo follow-up after LTX for whom DNA was available from both donor and recipients.Clinical data,all early complications including episodes and severity of AR and graft/patient survival were registered.The diagnosis of AR was based on clinical,biochemical and histological criteria.All suspected episodes of AR were biopsy confirmed.Key classical HLA loci(HLA-A,HLA-B,HLA-C and HLA-DRB1)were genotyped using Sanger sequencing.16 KIR genes were genotyped using a novel real time PCR approach which allows for determination of the diploid copy number of each KIR gene.Immunohistochemical staining for T(CD3),B(CD20)and natural killer(NK)cells(CD56 and CD57)were performed on liver biopsies from 3 different patient groups[primary sclerosing cholangitis(PSC),primary biliary cirrhosis and non-autoimmune liver disease],10 in each group,with similar grade of AR.RESULTS:Fourty-four(31%)patients were transplanted on the basis of PSC,40%of them had AR vs 24%in the non-PSC group(P=0.04).No significant impact of donor-recipient matching for HLA and KIR genotypes was detected.In the overall recipient population an increased risk of AR was detected for HLA-B*08(P=0.002,OR=2.5;95%CI:1.4-4.6),HLA-C*07(P=0.001,OR=2.4;95%CI:1.4-4.0)and HLA-DRB1*03(P=0.03,OR=1.9;95%CI:1.0-3.3)and a decreased risk for HLA-DRB1*04(P=0.001,OR=0.2;95%CI:0.1-0.5).For HLA-B*08,HLA-C*07 and DRB1*04 the associations remained evident in a subgroup analysis of non-PSC recipients(P=0.04,P=0.003 and P=0.02,respectively).In PSC recipients corresponding P values were 0.002,0.17 and 0.01 for HLA-B*08,HLA-C*07and DRB1*04,respectively.A dosage effect of AR prevalence according to the PSC associated HLA alleles was also notable in the total recipient population.For HLA-B*08 the frequency of AR was 56%in HLA-B*08homozygous recipients,39%in heterozygous recipients and 21%in recipients lacking HLA-B*08(P=0.02).The same was observed for the HLA-C*07 allele with AR in 57%,27%and 18%in recipients being homozygous,heterozygous and lacking HLA-C*07 respectively(P=0.003).Immunohistochemical analysis showed similar infiltration of T,B and NK cells in biopsies with AR in all three groups.CONCLUSION:We found significant associations between the PSC-associated HLA-B*08,HLA-C*07,HLADRB1*03 and HLA-DRB1*04 alleles and risk of AR in liver transplant recipients. | Bjarte Fosby Sigrid Nss Johannes R Hov James Traherne Kirsten M Boberg John Trowsdale Aksel Foss Pl-Dag Line Andre Franke Espen Melum Helge Scott Tom H Karlsen | 2014 | World Journal of Gastroenterology2014，20，14： | 0 |
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