|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A 14 nucleotide deletion mutation in the coding region of the PpBBX24 gene is associated with the red skin of“Zaosu Red”pear(Pyrus pyrifolia White Pear Group):a deletion in the PpBBX24 gene is associated with the red skin of pear显示文摘Red skin is an important quality trait for pear fruits and is determined by the concentration and composition of anthocyanins.The regulatory mechanism underlying anthocyanin accumulation is a popular topic in fruit research.Red mutants are ideal materials for studying the molecular mechanism of color diversity in pear.Although several red pear mutants have been cultivated and are in production,no exact locus containing the responsible genetic mutation has been identified.In this study,by combining the bulked segregant analysis with whole-genome sequencing,we identified a 14 nucleotide deletion mutation in the coding region of the PpBBX24 gene from the red pear mutant“Zaosu Red”.We further verified that the deletion was present only in the red mutant of“Zaosu”and in its red offspring,which was different from that which occurred in other red pear fruits.This deletion results in a coding frame shift such that there is an early termination of the PpBBX24 gene and loss of key NLS and VP domains from PpBBX24.The lost domains may reduce or alter the normal function of PpBBX24.In addition,we found that the transcript levels of the PpMYB10 and PpHY5 genes in red samples were significantly higher than those in green samples,whereas the results for the normal-type PpBBX24 gene were the opposite.We ultimately revealed that the 14 nucleotide deletion mutation in the coding region of the PpBBX24 gene is associated with the red skin of the“Zaosu Red”pear.This finding of somatic mutational events will be helpful for breeding new red pear cultivars and for understanding the regulatory mechanisms involved in pear skin pigmentation. | Chunqing Ou Xiaoli Zhang Fei Wang Liyi Zhang Yanjie Zhang Ming Fang Jiahong Wang Jixun Wang Shuling Jiang Zhihong Zhang | 2020 | Horticulture Research2020，7，1： | 4 |
| 2 | Characterization of Water Quality in Xiao Xingkai Lake:Implications for Trophic Status and Management显示文摘Increasing cases of lake eutrophication globally have raised concerns among stakeholders,and particularly in China.Evaluating the causes of eutrophication in waterways is essential for effective pollution prevention and control.Xiao Xingkai Lake is part of and connected to Xingkai(Khanka)Lake,a boundary lake between China and Russia.In this study,we investigated the spatio-temporal variabilities in water quality(i.e.,dissolved oxygen(DO),total nitrogen(TN),total phosphorus(TP),chemical oxygen demand(CODMn)and ammonium-nitrogen(NH4+-N))in Xiao Xingkai Lake,from 2012 to 2014,after which a Trophic Level Index was used to evaluate trophic status,in addition to the factors influencing water quality variation in the lake.The DO,TN,TP,CODMn and NH4+-N concentrations were 0.44-15.57,0.16-5.11,0.01-0.45,0.16-48.31,and 0.19-0.78 mg/L,respectively.Compared to the Environmental Quality Standards for surface water(GB 3838-2002)in China,the lake transitioned to an oligotrophic status in 2013 and 2014 from a mesotrophic status in 2012,TN and TP concentrations were the key factors influencing water quality of Xiao Xingkai Lake.Non-para-metric test results showed that sampling time and sites had significant effects on water quality.Water quality was worse in summer and in tourism and aquaculture areas,followed by agricultural drainage areas.Furthermore,lake water trophic status fluctuated between medium eutrophic and light eutrophic status from September 2012 to September 2014,and was negatively correlated with water level.Water quality in tourism and aquaculture sites were medium eutrophic,while in agricultural areas were light eutrophic.According to the results,high water-level fluctuations and anthropogenic activities were the key factor driving variability in physicochemical parameters associated with water quality in Xiao Xingkai Lake. | YU Shuling LI Xiaoyu WEN Bolong CHEN Guoshuang HARTLEYC Anne JIANG Ming LI Xiujun | 2021 | Chinese Geographical Science2021，31，3： | 4 |
| 3 | Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis显示文摘 | Changyong Li Yaxian Kong Hong Wang Shuling Wang Hao Yu Xin Liu Lin Yang Xiangming Jiang Lingsong Li Liying Li | 2009 | Journal of Hepatology2009，，6： | 2 |
| 4 | Corrigendum to “Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis” [J Hepatol 50 (2009) 1174–1183]显示文摘 | Changyong Li Yaxian Kong Hong Wang Shuling Wang Hao Yu Xin Liu Lin Yang Xiangming Jiang Lingsong Li Liying Li | 2009 | Journal of Hepatology2009，，5： | 1 |
| 5 | Crosslinkable fully aromatic poly(aryl ether ketone)s bearing macrocycle of aryl ether ketone显示文摘 | Xigui Yue Haibo Zhang Wenhui Chen Yishan Wang Shuling Zhang Guibin Wang Zhenhua Jiang | 2007 | Polymer2007，，16： | 1 |
| 6 | Oxygen availability,rather than ammonia,plays an important role in niche differentiation between comammox Nitrospira and canonical ammonia oxidizers in a neutral purple paddy soil显示文摘Dear Editor,Nitrification,the only process linking the oxidation and reduction of N in natural ecosystems,plays a vital role in maintaining global N equilibrium.Ammonia oxidation is the first and rate-limiting step of aerobic nitrification and is performed by ammonia-oxidizing bacteria(AOB). | Shuling WANG Zhihui WANG Yongpeng ZHAO Alan LWRIGHT Xianjun JIANG | 2023 | Pedosphere2023，33，2： | 0 |
| 7 | High-performance violet phosphorus photodetectors with van der Waals-assisted contacts显示文摘Black phosphorus(BP) as a narrow-bandgap two-dimensional semiconductor material has been extensively studied. And the allotrope violet phosphorus(VP) exhibits wide bandgap properties extending the application in the visible light band. However,due to the Schottky barrier of metal/semiconductor contacts(M/S), further device application of VP is limited. Here, VP-based photodetectors with van der Waals-assisted contact were demonstrated, achieving quasi-Ohmic M/S contacts. The output characteristics in dark conditions show ultralow current at the pA level. And the device exhibits a high current on-off ratio of 10~5and a fast response speed of 8.4 ms. Furthermore, we constructed the first allotropic photodetector based on BP and VP heterojunction. The device maintains ultralow dark current(~ pA) while exhibiting faster carrier transport, with 945 μs response time and polarization detection capability. These results offer an effective way to study the optoelectronic properties of VP and promote the study of allotropic heterojunction devices. | Hao Wang Shuling Liu Peng Wang Haonan Ge Yue Chen Hailu Wang Tengfei Xu Jiaxiang Guo Yuanchen Zou Wenrui Wei Ruiqi Jiang Fang Wang Piotr Martyniuk Jinshui Miao Weida Hu | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，9： | 0 |
| 8 | For more and purer hydrogen-the progress and challenges in water gas shift reaction显示文摘The water gas shift(WGS) reaction is a standard reaction that is widely used in industrial hydrogen production and removal of carbon monoxide. The improved catalytic performance of WGS reaction also contributes to ammonia synthesis and other reactions. Advanced catalysts have been developed for both high and low-temperature reactions and are widely used in industry. In recent years, supported metal nanoparticle catalysts have been researched due to their high metal utilization. Low-temperature catalysts have shown promising results, including high selectivity, high shift rates, and higher activity potential. Additionally, significant progress has been made in removing trace CO through the redox reaction in electrolytic cell. This paper reviews the development of WGS reaction catalysts, including the reaction mechanism, catalyst design, and innovative research methods. The catalyst plays a crucial role in the WGS reaction, and this paper provides an instant of catalyst design under different conditions. The progress of catalysts is closely related to the development of advanced characterization techniques.Furthermore, modifying the catalyst surface to enhance activity and significantly increase reaction kinetics is a current research direction. This review goals to stimulate a better understanding of catalyst design, performance optimization, and driving mechanisms, leading to further progress in this field. | Limin Zhou Yanyan Liu Shuling Liu Huanhuan Zhang Xianli Wu Ruofan Shen Tao Liu Jie Gao Kang Sun Baojun Li Jianchun Jiang | 2023 | Journal of Energy Chemistry2023，，8： | 0 |
| 9 | Redox-driven shifts in soil microbial community structure in the drawdown zone after construction of the Three Gorges Dam显示文摘Soil redox is a critical environmental factor shaping the microbial community structure and ultimately alters the nutrient cycling.However,the response of soil microbial community structure to prolonged or repeated redox fluctuations is not yet clear.To study the dynamic effects of prolonged redox disturbances to the soil microbial community structure,soil samples experiencing 8,5 and 0 alternating oxic-anoxic cycles within approximately 6 months each year were collected and the microbial community structure were evaluated using phospholipid fatty acid analysis(PLFA)profiles.Prolonged redox disturbances had significant effects on soil physiochemical properties and soil microbial community structure.The relative abundance of straight chain saturated PLFAs,cyclopropyl,and terminal-and mid-branched chain saturated PLFAs increased due to prolonged redox disturbances,but there was a consistent decrease in linear monounsaturated PLFAs and polyunsaturated PLFAs in the fluctuating zone.Prolonged redox disturbances had a negative impact on the total PLFA content(a proxy for biomass).Both the fluctuating zone(8-cycle and 5-cycle plots)and the never flooded zone(0-cycle plots)were dominated by Gram-positive bacteria and a low content of fungi,actinomycetes and protozoa.The fungi and protozoa abundance decreased significantly with an increase in the occurrence of alternating flooding-dry events,suggesting that the prolonged redox disturbance leads to high stress on the fungi and protozoa populations.Moreover,total organic matter(TOC)and C:N ratio,environmental factors that can be influenced by recurring redox fluctuations,also influenced the microbial community structure. | Shuling Wang Sarwee J.Faeflen Alan L.Wright Xia Zhu-Barker Xianjun Jiang | 2019 | Soil Ecology Letters2019，1，3： | 0 |
| 10 | Intratumoral CD103+CD8+T cells predict response to neoadjuvant chemoimmunotherapy in advanced head and neck squamous cell carcinoma显示文摘Background Immune cell heterogenicity is known to determine the therapeutic response to cancer progression.Neoadjuvant chemoimmunotherapy(NACI)has shown clinical benefits in some patients with advanced head and neck squamous cell carcinoma(HNSCC),but the underlying mechanism behind this clinical response is unknown.The efficacy of NACI needs to be potentiated by identifying accurate biomarkers to predict clinical responses.Here,we attempted to identify molecules predicting NACI response in advanced HNSCC.Methods We performed combined single-cell RNA sequencing(scRNA-seq)and multiplex immunofluorescence(mIHC)staining with tumor samples derived from NACI-treated HNSCC patients to identify a new tumor-infiltrating cell(TIL)subtype,CD103+CD8+TILs,associated with clinical response,while both in vitro and in vivo assays were carried out to determine its antitumor efficiency.The regulatory mechanism of the CD103+CD8+TILs population was examined by performing cell-cell interaction analysis of the scRNA-seq data and spatial analysis of the mIHC images.Results We established intratumoral CD103+CD8+TILs density as a determinant of NACI efficacy in cancers.Our scRNA-seq results indicated that the population of CD103+CD8+TILs was dramatically increased in the responders of NACI-treated HNSCC patients,while mIHC analysis confirmed the correlation between intratumoral CD103+CD8+TILs density and NACI efficacy in HNSCC patients.Further receiver operating characteristic curve analysis defined this TIL subset as a potent marker to predict patient response to NACI.Functional assays showed that CD103+CD8+TILs were tumor-reactive T cells,while programmed cell death protein-1(PD-1)blockade enhanced CD103+CD8+TILs cytotoxicity against tumor growth in vivo.Mechanistically,targeting the triggering receptor expressed on myeloid cells 2-positive(TREM2+)macrophages might enhance the population of CD103+CD8+TILs and facilitate antitumor immunity during NACI treatment.Conclusions Our study highlights the impact of intratumoral CD103+CD8+TILs density on NACI efficacy in different cancers,while the efforts to elevate its population warrant further clinical investigation. | Siqi Ren Tianjun Lan Fan Wu Suling Chen Xue Jiang Chuying Huo Zitian Li Shule Xie Donghui Wu Ruixin Wang Yanyan Li Lin Qiu Guoxin Huang Shurui Li Xiaojuan Wang Meifeng Cen Tingting Cai Zhaoyu Lin Jinsong Li Bowen Li | 2023 | Cancer Communications2023，43，10： | 0 |
| 11 | Establishment of green graphite industry:Graphite from biomass and its various applications显示文摘Resource-and energy-efficient biomass exploitation for green graphite production is one of the most effective strategies for satisfying graphite demand while minimizing energy consumption and carbon emissions.This study investigated green graphite production from biomass waste and its applications to establish a green graphite industry.Biomass pyrolysis and catalytic graphitization of biochar were studied first to produce green graphite.The optimized green graphite exhibited a reversible capacity of 264 mA h/g and 97%capacity retention over 100 cycles in a half-cell.Green graphite electrodes with a resistivity lower than 5μΩm were fabricated by using organic fraction bio-oil as a green binder.Other green graphite applications,including printing,conductive printing,pencils,and refractories,were also achieved.The overall process of graphite anode and electrode synthesis from biomass waste and short-rotation energy crops was modeled.Approx.95 kg of battery graphite or 109 kg of metallurgical graphite electrodes can be produced per ton of biomass with low primary energy consumption and carbon footprint.Prominently,the modeling result and life cycle assessment demonstrated that,for the production of battery graphite from biomass waste,net-negative-CO_(2)emissions(−0.57 kg CO_(2)-eq/kg graphite powders)with net-negative-primary energy consumption(−28.31 MJ/kg graphite powders)was achieved. | Ziyi Shi Shule Wang Yanghao Jin Lingfeng Zhao Shiwei Chen Hanmin Yang Yuxiao Cui Rikard Svanberg Chuchu Tang Jianchun Jiang Weihong Yang PäGJösson Tong Han | 2023 | SusMat2023，3，3： | 0 |
| 12 | THERMAL PROPERTIES OF NANOCRYSTALLINE Fe_78B_13Si_9 ALLOY显示文摘A new method was developed for preparing nanocrystalline alloy made of the identi-cal compositional Fe78B13Si9 amorphous ribbon by suitable isothermal annealing.Itsmicrostructure and some structure-sensitive properties.including thermal expansion,spe-cific heat,etc.,have been studied and measured.Comparative analysis of properties wasalso carried out with amorphous and coarse-grained crystalline alloys of same composi-tion,thus.it is believed that so novel differences in properties from usual materials wouldbe made by the particular microstructure of short range disorder of the nanocrystallinealloy. | TONG Huayu,DING Bingzhe,JIANG Honggang,LI Shuling,LI Gusong,WANG Jingtang State Key Laboratory of RSA,Institute of Metal Research.Academia Sinica.Shenyang,China | 1992 | Acta Metallurgica Sinica(English Letters)1992，5，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员