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| 1 | Hepatic clearance measured with ^(99m)Tc-GSA single-photon emission computed tomography to estimate liver fibrosis显示文摘AIM: To evaluate the clinical utility of hepatic clearance(HC) measured with technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl human serum albumin(99mTc-GSA) single-photon emission computed tomography(SPECT) to estimate the degree of liver fibrosis.METHODS:Seventy-eight consecutive patients who underwent initial hepatectomy due to hepatocellular carcinoma were enrolled in this study.Indocyanine green clearance(ICG R15),quantitative indices estimated by 99mTc-GSA[the receptor index(LHL15 and HH15)and HC via SPECT analysis],and conventional liver function tests were performed before hepatectomy.Correlations among the quantitative indices for liver functional reserve,conventional liver function tests,andthe degree of liver fibrosis were evaluated.RESULTS:The degree of liver fibrosis was correlated with ICG R15,HH15,LHL15,and HC.HC showed the best correlation with conventional liver function tests.According to multivariate analysis,HC and LHL15 were significant independent predictors of severe fibrosis.HC was the most valuable index for predicting severe fibrosis.CONCLUSION:HC measured with 99mTc-GSA SPECT is a reliable index for assessing liver fibrosis before hepatectomy. | Masahiko Taniguchi Atsutaka Okizaki Kenji Watanabe Koji Imai Koichiro Uchida Takahiro Einama Noriyuki Shuke Naoyuki Miyokawa Hiroyuki Furukawa | 2014 | World Journal of Gastroenterology2014，20，44： | 11 |
| 2 | Effect of Bushenyisui Formula on brain tissue apoptosis and Bcl-2 in beta-amyloid protein-induced Alzheimer's disease rat models显示文摘OBJECTIVE:To investigate the effect of Bushenyisui Formula on cell apoptosis and positive B cell lymphoma(Bcl-2) in the Brain of rat models of Alzheimer's disease(AD) induced by beta-amyloid protein(Aβ) and the mechanism underlying the effect.METHODS:Total of 40 SD rats,20 females and 20 males,were randomly assigned to 4 groups,controlled group(A),model group(B),conventional treatment group(C) and Bushenyisui Formula treatment(BYFT) group(D),10 rats in each group.Aβ 1-42 was injected into the bilateral hippocampus of the rats in group B,C and D to create the models of AD.Sham operation was performed on the rats of group A in the same way by injecting equal volume of 0.9% sodium chloride solution into their bilateral hippocampus.5 days after operation,Bushenyisui Formula was intraperitoneally administered at a dose of 450 mg/kg to the rats of group D(QD) for 20 days.Equalvolumeof0.9%sodiumchloridesolution wasintraperitoneallyinjectedintotheratsofgroupB withthesameprocedure.C suspension(20 mg/mL) was intraperitoneally injected into the rats of group B with the same procedure.The number of apoptotic cells in Brain and the positive Bcl-2 were counted.The changes of learning and memory abilities were evaluated usingY-maze.RESULTS:Right after the establishment of the models,group B,C and D compared to group A respectively,the outcomes of Y-maze were significantly different from that of group A,which suggested obvious learning and memory disorder in those groups(P<0.01).After treatment,the times of electronic shocks of group C and D were significantly less than that of group B(P<0.05),and the numbers of apoptotic cells and positive Bcl-2 were significantly different from those of group B,apoptotic sells' number of group C and D smaller than that of group B and the number of positive Bcl-2 greater than that of group B.CONCLUSION:Bushenyisui Formula could increase the number of Bcl-2 in brain,which improved the function of nervous system pertaining to learning and memory abilities. | Shuke Cui Yan Sun Chengzang Liu | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 6 |
| 3 | Deformation mechanisms of WIPP backfill 显示文摘 | Wang Ming L Miao Shuke Maji Arup K | 1996 | Radioactive Waste Management and Environmental Restoration1996，20，23： | 1 |
| 4 | Demonstration of double chambered right ventricle on myocardial perfusion SPECT显示文摘 | Sugiki K Ajili H | 1998 | Clin Nucl Mde1998，23，4： | 1 |
| 5 | (99m)TcDTPA dynamic SPECT and CT volumetry for measuring split renal function in live kidney donors显示文摘 | Miyazaki C Harada H Shuke N | 2010 | An Nucl Med2010，24，3： | 1 |
| 6 | Accumulation of Tc-99m HMDP in Extramedullary Plasmacytoma of the Stomach显示文摘 | Shuke N Okizaki A Yamamoto W | 2001 | Clin Nucl Med2001，26，4： | 1 |
| 7 | Optical microscopic study on the morphologies of isotactic polypropylene induced by its homogeneity fibers 显示文摘 | Li Huihui Jiang Shidong Wang Jijun Wang Dujin Yang Shuke | 2003 | Macromolecules2003，36，8： | 1 |
| 8 | Estimation of fractional liver uptake and blood retention of 99mTc-DTPA-galactosyl human serum albumin: an application of a simple graphical method to dynamic SPECT显示文摘 | N SHUKE T ABURANO A OKIZAKI C ZHAO K NAKAJIMA K YOKOYAMA S KINUYA N WATANABE T MICHIGISHI N TONAMI | 2003 | Nuclear Medicine Communications2003，，5： | 1 |
| 9 | (99m)Tc-DTPA dymamic SPECT and CT volumetry for measuring split renal function in live kidney donors显示文摘 | Miyazaki C Harada H Shuke N | 2010 | An Nucl Med2010，24，： | 1 |
| 10 | Sub-super bone scan caused by bone marrow involvement of prostate cancer显示文摘 | Seo Y Shuke N Yamamoto W | 1999 | Ann Nucl Med1999，13，5： | 1 |
| 11 | Synthesis of a high trans-1,4-butadiene/isoprene copolymers with supported titanium catalysts 显示文摘 | He Aihua Huang Baochen Jiao Shuke | 2003 | Journal of Applied Polymer Science2003，89，7： | 1 |
| 12 | A Solar Radio Spectrometer at 5.2–7.6?GHz显示文摘 | Huirong Ji Qijun Fu Yuying Liu Congling Cheng Zhijun Chen Yihua Yan Leping Zheng Zongjun Ning Chengmin Tan Debang Lao Shuke Li Jiyong Gao Zhiqiang Wang Minhong Yu | 2003 | Solar Physics2003，，2： | 1 |
| 13 | Internal friction mechanism of Fe-19Mn alloy at low and high strainamplitude显示文摘 | Huang Shuke Huang Wenrong Liu Jianhui | 2013 | Materials Science and Engineering A2013，560，： | 1 |
| 14 | Amplitude frequency response characteristics of Fe-based damping alloysimple beams under forced vibrations显示文摘 | Huang Shuke Zhou Danchen Liu Jianhui | 2011 | Advanced Materials Research2011，，： | 1 |
| 15 | Effects of strain amplitude and temperature on the damping capacity of anFe-19Mn alloy with different microstructures显示文摘 | Huang Shuke Zhou Danchen Liu Jianhui | 2010 | Materials Characterization2010，61，11： | 1 |
| 16 | Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT 显示文摘 | Shuke N Okizaki A Kino S | 2003 | J Nucl Med2003，44，： | 1 |
| 17 | Effect of solution temperature on shape memory effect of CuZnAl alloy 显示文摘 | Huang Shuke Li Ning Mo Huaqiang | 2005 | Journal of Sichuan University : Engineering Science Edition2005，37，2： | 1 |
| 18 | Increased uptake of99mTc-HL91 in tumor cells exposed to X-ray radiation显示文摘 | Seigo Kinuya Kunihiko Yokoyama Shota Konishi Xiao-Feng Li Naoto Watanabe Noriyuki Shuke Tamio Aburano Teruhiko Takayama Takatoshi Michigishi Norihisa Tonami | 2000 | Annals of Nuclear Medicine2000，，2： | 1 |
| 19 | Scintigraphic evaluation of pamidronate and corticosteroid therapy in a patient with progressive diaphyseal dysplasia (Camurati-Engelmann disease)显示文摘 | Inaoka T Shuke N Sato J | | 0，，： | 1 |
| 20 | Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT显示文摘 | Shuke N Okizaki A Kino S | 2003 | J Nucl Med2003，44，3： | 1 |
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