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| 1 | Comparison of half-molar sodium lactate and mannitol to treat brain edema in severe traumatic brain injury:A systematic review显示文摘Purpose:Hypertonic fluids such as mannitol and half-molar sodium lactate are given to treat intracranial hypertension in patients with severe traumatic brain injury(TBI).In this study,sodium lactate was compared to mannitol in patients with TBI to investigate the efficacy in reducing intracranial pressure(ICP).Methods:This study was a systematic review with literature research on articles published in any year in the databases of PubMed,ScienceDirect,Asian Journal of Neurosurgery,and Cochrane Central Register of Controlled Trials.The keywords were'half-molar sodium lactate','mannitol','cerebral edema or brain swelling',and'severe traumatic brain injury'.The inclusion criteria were(1)studies published in English,(2)randomized control trials or retrospective/prospective studies on TBI patients,and(3)therapies including half-molar sodium lactate and mannitol and(4)sufficient data such as mean difference(MD)and risk ratio(RR).Data analysis was conducted using Review Manager 5.3.Results:From 1499 studies,a total of 8 studies were eligible.Mannitol group reduced ICP of 0.65 times(MD 0.65;p=0.64)and improved cerebral perfusion pressure of 0.61 times(MD 0.61;p=0.88),better than the half-molar group of sodium lactate.But the half-molar group of sodium lactate maintained the mean arterial pressure level of 0.86 times,better than the mannitol group(MD 0.86;p=0.09).Conclusion:Half-molar sodium lactate is as effective as mannitol in reducing ICP in the early phase of brain injury,superior over mannitol in an extended period.It is able to prevent intracranial hypertension and give better brain tissue perfusion as well as more stable hemodynamics.Blood osmolarity is a concern as it increases serum sodium. | Abdul Hafid Bajamal Tedy Apriawan I.G.M.Aswin R.Ranuh Franco Servadei Muhammad Faris Asra Al Fauzi | 2021 | Chinese Journal of Traumatology2021，24，6： | 2 |
| 2 | Importance of a reliable admission Glasgow coma scale for determining the need of evacuation of posttraumatic subdural hematomas: a prospective study of 65 patients显示文摘 | Servadei F Nasi MT Cremonini AM | 1998 | J Trauma1998，44，： | 1 |
| 3 | Effect of Italy's motorcycle helmet law on traumatic brain injuries显示文摘 | Servadei F Begliomini C Gardini E | 2003 | Inj Prev2003，9，3： | 1 |
| 4 | Extradural haematomas:how many deaths can be avoided? Protocol for early detection of haematoma in minor head injuries显示文摘 | Servadei F Vergonl G Staffa G | 1995 | Acta Neurochir( Wien )1995，133，1： | 1 |
| 5 | The value of the 'worst'computed tomographic scan in clinical studies of moder-ate and severe head injury显示文摘 | Murray GD Penny K | 2000 | Neurosurgery2000，46，1： | 1 |
| 6 | Progression of traumatic intracerebral hemorrhage:a prospective observational study显示文摘 | Narayan R K Maas I R Servadei F et a| | 2008 | J Neurotrauma2008，25，3： | 1 |
| 7 | The value of the 'worst' computed tomographic scan in clinical studies of moderate and severe head injury显示文摘 | Servadei Murray GD Penny K | 2000 | Neurosurgery2000，445，1： | 1 |
| 8 | Early predictors of unfavourable outcome in subjects with moderate head injury in the emergency department显示文摘 | Fabbri A Servadei F Marchesini G | 2008 | J Neurol Neurosurg Psychiatry2008，79，5： | 1 |
| 9 | Prognostic factors in severely head injured adultpatients with epidural haematoma显示文摘 | Servadei F | | Acta Neurochir(Wien) I997 139(4)0，，： | 1 |
| 10 | Progression of traumaticintracerebral hemorrhage: a prospective observational study 显示文摘 | Narayan RK Maas Al Servadei F | 2008 | JNeurotrauma2008，25，6： | 1 |
| 11 | CT prognostic factors in acute subdural haematomas: the value of the 'worstj CT schn 显示文摘 | Servadei F Nasi MT Giuliani G | 2000 | Br J Neurosurg2000，14，2： | 1 |
| 12 | Coagulopathy and NICE recommendations for patients with mild head injury显示文摘 | FABBRI A VANDELLI A SERVADEI F | 2004 | Neurology Neurosurgery &Phsychiatry2004，75，12： | 1 |
| 13 | Traumatic subarachnoid hemorrhage: demorgraphic and clinical study of 750 patients from the European brain injury consortium survey of head injuries 显示文摘 | Servadei F Murray GD Teasdale GM | 2002 | Neurosurgery2002，50，： | 1 |
| 14 | The value of the calcium binding protein S100in the management of patients with traumatic brain injury显示文摘 | Schiavi P Laccarino C Servadei F | 2012 | Acta Biomed2012，83，1： | 1 |
| 15 | Evolving brain lesions in the first 12hours after head injury: analysis of 37 comatose patients显示文摘 | Servadei F Nanni A Nasi M | 1995 | Neurosurgery1995，37，： | 1 |
| 16 | The value of the calcium binding protein S100 in the management of patients with traumatic brain injury显示文摘 | Schiavi P Laccarino C Servadei F | | 0，，01： | 1 |
| 17 | Progression of traumatic intracerebral hemorrhage:a prospective observational study显示文摘 | Narayan RK Maas AI Servadei F | | 0，，06： | 1 |
| 18 | The value of the calcium binding protein SIO0 in the management of patients with traumatic brain injury 显示文摘 | Schiavi P Laccarino C Servadei F | 2012 | Acta Bi- omed2012，83，1： | 1 |
| 19 | Traumatic intracerebellar hemorrhage:Clinicoradiological analysis of 81 patients显示文摘 | Avella D Servadei F Scerrati M | 2002 | Neurosurgery2002，50，1： | 1 |
| 20 | Surgical Management of Acute Epidural Hematomas显示文摘 | M Ross Bullock Randall Chesnut Jamshid Ghajar David Gordon Roger Hartl David W. Newell Franco Servadei Beverly C. Walters Jack E. Wilberger | 2006 | Neurosurgery . 2006 (3 Su)2006，，3： | 1 |
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