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| 1 | The prevalence of transfusion transmitted virus infection in blood donors显示文摘INIRODUCIIONA newly discovered DNA virus,transfusiontransmitted virus (TTV),was reported as a cause ofpost-transfusion hepatitis of unknown etiology inJapan.In order to investigate TTV prevalence insouthern China,a study was carried out amongblood donors,patients with liver diseases andhemodialysis to determine the epidemiologicalcharateristics. | Cheng Hui Huang Yu Sen Zhou Ru Guang Chen Chun Ying Xie Hai Tao Wang | 2000 | World Journal of Gastroenterology2000，6，2： | 7 |
| 2 | Single - incision thoraeoscopie surgery for primary spontaneous pneumotho- rax显示文摘 | Pin - Ru Chen Chien - Kuang Chen Yu - Sen Lin | 2011 | J Cardiothoracic Surg2011，6，： | 1 |
| 3 | Low-loading gold in situ doped with sulfur by biomolecule-assisted approach for promoted electrochemical carbon dioxide reduction显示文摘For electrochemical carbon dioxide reduction(CO_(2)RR),CO_(2)-to-CO conversion is considered an ideal route towards carbon neutrality for practical applications.Gold(Au)is known as a promising catalyst with high selectivity for CO;however,it suffers from high cost and low mass-specific activity.In this study,we design and prepare a catalyst featuring uniform S-doped Au nanoparticles on N-doped carbon support(denoted as S-Au/NC)by an in situ synthesis strategy using biomolecules.The S-Au/NC displays high activity and selectivity for CO in CO_(2)RR with a Au loading as low as 0.4 wt.%.The Faradaic efficiency of CO(FECO)for S-Au/NC is above 95%at−0.75 V(vs.RHE);by contrast,the FECO of Au/NC(without S)is only 58%.The Tafel slope is 77.4 mV·dec−1,revealing a favorable kinetics process.Furthermore,S-Au/NC exhibits an excellent long-term stability for CO_(2)RR.Density functional theory(DFT)calculations reveal that the S dopant can boost the activity by reducing the free energy change of the potential-limiting step(formation of the*COOH intermediate).This work not only demonstrates a model catalyst featuring significantly reduced use of noble metals,but also establishes an in situ synthesis strategy for preparing high-performance catalysts. | Meijie Tan Xiaoqian Han Sen Ru Chao Zhang Zhouru Ji Zhaolin Shi Guomeng Qiao Yunying Wang Ruixue Cui Qiquan Luo Jiqing Jiao Yaguang Li Tongbu Lu | 2023 | Nano Research2023，16，2： | 1 |
| 4 | FEM for Brake Discs of SiC 3D Continuous Ceramic Reinforced 7075 Aluminum Alloy for CRH3 Trains Applying Emergency Braking显示文摘 | Yu Liang Jiang Yan Li Lu Sen Kai Ru Hong Qiang Fang Ming | 2012 | Applied Mechanics and Materials2012，，120： | 1 |
| 5 | Analysis of clinical manifestations,mutant gene and encodedprotein in two Chinese MYH9-related disease families显示文摘 | Yi Y Sen Zhang G Xu M San Ling Z Ru Shao X Zeng Li J | 2006 | ClinChim Acta2006，373，12： | 1 |
| 6 | Preliminary Study on the Efficacy of a New Zero-load X-ray Protector for Coronary Intervention显示文摘The application of radiation for medical examination and treatment has increased rapidly since the 1980 s.In contrast to other radiation-based imaging and medical treatment,medical staff working in fluoroscopic-based procedures have to suffer radiation exposure.Its harm is well known not only for the deterministic effects causing cataract or dermatitis[1],but also for the stochastic effects with increased risks of chromosomal damage or malignant tumors[2]. | LU Yi Abdus Samee WANG Jin WANG Fu Ru TANG Shao Wen YANG Ming Wen YE Sen LI Jin Shuang GONG Xiao Xuan LI Yong LI Chun Jian | 2020 | Biomedical and Environmental Sciences2020，33，11： | 1 |
| 7 | Numerical investigation on dynamic characteristics of flow field in cyclone separators with different dust hopper structures显示文摘The dynamic characteristics of flow field in cyclone separators with different dust hopper structures were studied by coupling Reynolds Stress Model(RSM)and Lagrangian Particle Tracking(LPT)methods.The characteristic frequencies of cylinder section,cone section and dust hopper were calculated as f_(1)=53 Hz,f_(2)=65 Hz,and f_(3)=8 Hz by using Fast Fourier Transform(FFT)method,respectively.Based on the effects of f3 on the motion of vortex,the separated space was divided into none affected region,weakly affected region,and strongly affected region.The characteristic frequency of dust hopper increased with the decrease of dust hopper diameter,while it was independent of the height.The dust hopper with d=1.5D(model D3)and h=1.5D(model H3)can significantly decrease the effect of back-mixing on the motion of inner vortex,which is beneficial to improve the efficiency of cyclone separator. | Liyun Zhu Sen Wang Yi Ru Jianzhu Wang Pengju Yang Anjun Li Zhenfei Ma Zhenbo Wang | 2023 | Particuology2023，，11： | 0 |
| 8 | Mono-2-ethylhexyl Phthalate Promotes Migration and Invasion by Regulating the Epithelial-Mesenchymal Transition in SHSY5Y Cells显示文摘Neuroblastoma(NB)is the most common extracranial solid tumor of childhood.It accounts for 8%–10%of all malignant tumors in children^([1])and results in a heavy burden to the life and health of children.NB is a complex disease,and its occurrence is related to exposure to environmental risk factors. | XU Qi ZHANG Bo LI Xu YE Jia Ming HUO Chuan Yi YIN Jian Li ZHANG Ru Xuan ZHAO Wei Sen QI Wen YE Lin | 2022 | Biomedical and Environmental Sciences2022，35，3： | 0 |
| 9 | TCP-1,a novel peptide to diagnose early colon cancer显示文摘A nine cyclic peptide(TCP-1)showed excellent specificity for colon cancer.TCP-1 binds with human tumor tissues at early stages and mice tumor with diameters of 1-4 mm,suggesting that TCP-1 may be used for early diagnosis of colon cancer.The mechanism of the targeted binding of TCP-1 to colon cancer was also studied using immunoprecipitation,LC-MS and bioinformatics.After screening and identifying of the possible binding target proteins of TCP-1,keratin,typeⅡcytoskeletal 5 was speculated to be the specific binding target protein of TCP-1 in human tumor tissue.Pharmacokinetics studies were conducted to investigate the target-mediated drug disposition of the new tumor-specific peptide by LC-MS/MS.The tissue distribution study showed that TCP-1 was found only in colon tumors(the target site)in tumor mice did not bind to any other tissues.Conjugating TCP-1 to tumor markedly increased its removal rate from blood circulation but mildly extended its staying time in vivo.In tumor mice,a lower AUC of TCP-1(reduced by almost 35%)and 2-fold higher clearance were found compared to that of normal mice.The proposed metabolic pathway of TCP-1 in the kidney was also determined using LC-MS^(n)-IT-TOF.The high specificity and low toxicity of the peptide may be caused by its extremely tight binding to the targets.Potential applications for future clinical use,including MRI and PET/CT were also explored,and this research may promote the development of colon cancer diagnostic technology research and provide new ideas and technical routes for tumor diagnostic technology. | Hang Yu Baoying Wen Min Huang Ru Feng Libin Pan Manyi Xu Hao Lin Lin Cong Sen Zhang Yan Li Chi-Hin Cho Chongjing Zhang Xiaoguang Chen Yan Wang | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
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