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| 1 | 骨盆底功能障碍的静态和动态MR成像表现显示文摘目的前瞻性地分析同期静态和动态MR影像,确定压力性尿失禁(SUI)、盆腔脏器脱出(POP)和肛门失禁是否与特定的盆底异常相关。方法本研究经伦理委员会批准,并获得所有受试者知情同意。共计59例女性,其中15例未生育女性(平均年龄25.6岁)为对照组,病人44例(平均年龄43.4岁)。病人组依据主要症状分为4组。结构紊乱分析采用静态T2加权扰相自旋回波影像,功能异常的诊断则采用功能动态(电影)平衡快速场回波影像。记录5个盆底支持结构的测量结果。两种MRI影像联合分析以确定主要异常。 | R.F. El Sayed S. El Mashed A. Farag M.M. Morsy M.S. A bdel Azim. 赵艳萍(译) 刘文亚(校) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 12 |
| 2 | Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients显示文摘AIM To evaluate the reversibility of minimal hepatic encephalopathy(MHE) following liver transplantation(LT) in Egyptian cirrhotic patients. METHODS This prospective study included twenty patients with biopsy-proven liver cirrhosis listed for LT and twenty ageand sex-matched healthy control subjects. All underwent neuro-psychiatric examination, laboratory investigations, radiological studies and psychometric tests including trail making test A(TMT A), TMT B, digit symbol test and serial dotting test. The psychometric hepatic encephalopathy score(PHES) was calculated for patients to diagnose MHE. Psychometric tests were repeated six months following LT in the cirrhotic patient group. RESULTS Before LT, psychometric tests showed highly significant deficits in cirrhotic patients in comparison to controls(P < 0.001). There was a statistically significant improvement in test values in the patient group after LT; however, their values were still significantly worse than those of the controls(P < 0.001). The PHES detected MHE in 16 patients(80%) before LT with a median value of -7 ± 3.5. The median PHES value was significantly improved following LT, reaching-4.5 ± 5(P < 0.001), and the number of patients with MHE decreased to 11(55%). The pre-transplant model for end-stage liver disease(MELD) score ≥ 15 was significantly related to the presence of post-transplant MHE(P = 0.005). More patients in whom reversal of MHE was observed had a pre-transplant MELD score < 15.CONCLUSION Reversal of MHE in cirrhotic patients could be achieved by LT, especially in those with a MELD score < 15. | Mahmoud A Osman Moataz M Sayed Khaled A Mansour Shereen A Saleh Wesam A Ibrahim Sara M Abdelhakam Mohamed Bahaa Wael A Yousry Hosam S Elbaz Reginia N Mikhail Azza M Hassan Ehab H Elsayed Dalia A Mahmoud | 2016 | World Journal of Hepatology2016，8，30： | 11 |
| 3 | Acaricidal activity of different extracts from Syzygium cumini L.Skeels(Pomposia) against Tetranychus urticae Koch显示文摘Objective:To investigate the acaricidal activity of different extracts from Syzygium cumini(S.cumini)(Pomposia)againsst Tetranyckus urticae Koch(71 urticae)and the biochemical changes in antioxidants enzymes.Methods:Six extracts of S.cumini(Pomposia)at concentrations of 75,150 and 300μg/mL were used to control T.urticae(Koch).Results:The ethanol extract showed the most efficient acaricidal activity agent against T.urticae(98.5%)followed by hexane extract(94.0%),ether and ethyl acetate extract(90.0%).The LC_(50)values of the promising extract-were 85.0,101.0,102.0 and 98.0μ/mL,respectively.The activities of enzymes including ascorbate peroxidase(APX),peroxidase(POD),superoxide dismutase(SOD)and catalase(CAT)in susceptible mites were increased.The activities of all antioxidant enzymes reach the maximum value in mites at LC_(50)with ethanol and ethyl acetate extracts,respectively.Conclusions:The extract of S.cumini has acaricidal acivity against T.urticae,and the ethanol extract is the most efficient. | Abd El-Moneim MR Afify Hossam S El-Beltagi Sayed A Fayed Emad A Shalaby | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，5： | 5 |
| 4 | Interaction of insulin with prokinetic drugs in STZ-induced diabetic mice显示文摘AIM:To study the possible interactions of metoclopramide,domperidone and erythromycin in streptozotocin-induced diabetic mice treated with insulin by various parameters.METHODS:Effects of the individual as well as combined drugs were studied in diabetic mice via estimation of the blood glucose and serum insulin levels,small intestinal transit(SIT),gastric emptying(GE),xylose absorption and glucose tolerance tests.Groups were given insulin 2 IU/kg s.c.,metoclopramide 20 mg/kg p.o.,domperidone 20 mg/kg p.o.and erythromycin 6 mg/kg p.o.individually and in combination.There were also normal and diabetic control groups.The first set of experiments was carried out to investigate the subchronic effect on blood glucose and serum insulin levels in diabetic mice of one week of daily dose administration of the tested drugs individually as well as the combination of insulin with each prokinetic drug.The other five sets of experiments were carried out to investigate the acute effect of a single dose of each drug individually and in combination on blood glucose and serum insulin levels,SIT,GE,oral xylose absorption and glucose tolerance tests.RESULTS:The study included the prokinetic drugs metoclopramide(20 mg/kg),domperidone(20 mg/kg) and erythromycin(6 mg/kg),as well as insulin(2 IU/kg),which was individually effective in decreasing SIT,enhancing GE and increasing xylose absorption significantly in diabetic mice.Erythromycin tended to decrease blood glucose level and increase serum insulin level after 1 wk of daily administration in diabetic mice.Erythromycin potentiated the effect of insulin on blood glucose level and serum insulin level whereas other prokinetic agents failed to do so after repeated dose administration in diabetic mice.Metoclopramide or erythromycin in combination with insulin significantly decreased SIT,in diabetic mice,to lower levels than with insulin alone.Administration of prokinetic drugs along with insulin antagonized the action of insulin on xylose absorption.These combinations also increased the rate of glucose absorption from the gut.CONCLUSION:The present study suggests that prokinetic drugs could potentially improve glycemic control in diabetic gastroparesis by allowing a more predictable absorption of nutrients,matched to the action of exogenous insulin.The use of prokinetics,such as erythromycin,may be interesting in the clinic in decreasing the need for insulin in diabetic patients.The dose of insulin may be safely decreased with erythromycin in chronic treatments. | Mohamed A Fouad Shalaby Hekma A Abd El Latif Mostafa E El Sayed | 2013 | World Journal of Gastrointestinal Pharmacology and Therapeutics2013，4，2： | 3 |
| 5 | The pharmacokinetics of the prostaglandin E1 analogue misoprostol in plasma and colostrum after postpartum oral administration显示文摘 | Hany Abdel-Aleem José Villar A Metin Gülmezoglu Sayed A Mostafa Alaa A Youssef Mahmoud Shokry Bernhard Watzer | 2002 | European Journal of Obstetrics and Gynecology2002，，1： | 2 |
| 6 | Acid and non-acid reflux in patients refractory to proton pump inhibitor therapy:Is gastroparesis a factor?显示文摘AIM:To determine whether an increased number and duration of non-acid reflux events as measured using the multichannel intraluminal impedance pH(MII-pH)is linked to gastroparesis(GP).METHODS:A case control study was conducted in which 42 patients undergoing clinical evaluation for continued symptoms of gastroesophageal reflux disease(both typical and atypical symptoms)despite acid suppression therapy.MII-pH technology was used over 24 h to detect reflux episodes and record patients’symptoms.Parameters evaluated in patients with documented GP and controls without GP by scintigraphy included total,upright,and supine number of acid and non-acid reflux episodes(pH<4 and pH>4,respectively),the duration of acid and non-acid reflux in a 24-h period,and the number of reflux episodes lasting longer than 5 min.RESULTS:No statistical difference was seen between the patients with GP and controls with respect to the total number or duration of acid reflux events,total number and duration of non-acid reflux events or the duration of longest reflux episodes.The number of nonacid reflux episodes with a pH>7 was higher in subjects with GP than in controls.In addition,acid reflux episodes were more prolonged(lasting longer than 5min)in the GP patients than in controls;however,these values did not reach statistical significance.Thirty-five patients had recorded symptoms during the 24 h study and of the 35 subjects,only 9%(n=3)had a positive symptom association probability(SAP)for acid/non-acid reflux and 91%had a negative SAP.CONCLUSION:The evaluation of patients with a documented history of GP did not show an association between GP and more frequent episodes of non-acid reflux based on MII-pH testing. | Anna Tavakkoli Bisma A Sayed Nicholas J Talley Baharak Moshiree | 2013 | World Journal of Gastroenterology2013，19，37： | 2 |
| 7 | Hamstring autograft utilization in reconstructing anterior cruciate ligament:Review of harvesting techniques,graft preparation,and different fixation methods显示文摘Rupture of the anterior cruciate ligament(ACL)is a common orthopedic injury.Various graft options are available for the reconstruction of ruptured ACL.Using the hamstring muscle as an autograft was first described in 1934,and it remains a commonly harvested graft for ACL reconstruction.Hamstring autografts can be harvested using the traditional anteromedial approach or the newer posteromedial technique.An isolated semitendinosus tendon can be used or combined with the gracilis tendon.There are numerous methods for graft fixation,such as intra-tunnel or extra-tunnel fixation.This comprehensive review discusses the different hamstring muscle harvesting techniques and graft preparation options and fixation methods.It provides a comprehensive overview for choosing the optimal surgical technique when treating patients. | Waleed Albishi Baraa Baltow Nora Albusayes Ameer A Sayed Hamza M Alrabai | 2022 | World Journal of Orthopedics2022，13，10： | 2 |
| 8 | Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model显示文摘AIM: To develop a mathematical model for the early detection of hepatocellular carcinoma(HCC) with a panel of serum proteins in combination with α-fetoprotein(AFP).METHODS: Serum levels of interleukin(IL)-8, soluble intercellular adhesion molecule-1(s ICAM-1), soluble tumor necrosis factor receptor Ⅱ(s TNF-RⅡ), proteasome, and β-catenin were measured in 479 subjects categorized into four groups:(1) HCC concurrent with hepatitis C virus(HCV) infection(n = 192);(2) HCV related liver cirrhosis(LC)(n = 96);(3) Chronic hepatitis C(CHC)(n = 96); and(4) Healthy controls(n = 95). The R package and different modules for binary and multi-class classifiers based on generalized linear models were used to model the data. Predictive power was used to evaluate the performance of the model. Receiver operating characteristic curve analysis over pairs of groups was used to identify the best cutoffs differentiating the different groups. RESULTS: We revealed mathematical models, based on a binary classifier, made up of a unique panel of serum proteins that improved the individual performance of AFP in discriminating HCC patients from patients with chronic liver disease either with or without cirrhosis. We discriminated the HCC group from the cirrhotic liver group using a mathematical model(-11.3 + 7.38 × Prot + 0.00108 × s ICAM + 0.2574 ×β-catenin + 0.01597 × AFP) with a cutoff of 0.6552, which achieved 98.8% specificity and 89.1% sensitivity. For the discrimination of the HCC group from the CHC group, we used a mathematical model [-10.40 + 1.416 × proteasome + 0.002024 × IL + 0.004096 × s ICAM-1 +(4.251 × 10-4) × s TNF + 0.02567 ×β-catenin + 0.02442 × AFP] with a cutoff 0.744 and achieved 96.8% specificity and 89.7% sensitivity. Additionally, we derived an algorithm, based on a binary classifier, for resolving the multi-class classification problem by using three successive mathematical model predictions of liver disease status. CONCLUSION: Our proposed mathematical model may be a useful method for the early detection of different statuses of liver disease co-occurring with HCV infection. | Abdel-Rahman Nabawy Zekri Amira Salah El-Din Youssef Yasser Mabrouk Bakr Reham Mohamed Gabr Ola Sayed Ahmed Mostafa Hamed Elberry Ahmed Mahmoud Mayla Mohamed Abouelhoda Abeer A Bahnassy | 2016 | World Journal of Gastroenterology2016，22，16： | 2 |
| 9 | Linear estimation in Krein spaces part Ⅱ: Applications 显示文摘 | Sayed A H Kailath T | 1996 | IEEE Transactions on Automatic Control1996，41，1： | 1 |
| 10 | Networkbased wireless location显示文摘 | Sayed A H Tarighat A Khaiehnouri N | 2005 | IEEE Signal Processing Magazine2005，，7： | 1 |
| 11 | Optimal linear cooperation for spectrum sensing in cognitive radio networks 显示文摘 | QUAN Z CUI SH G SAYED A H | 2008 | IEEE Selected in Signal Processing2008，2，1： | 1 |
| 12 | Shape - controlled synthesis of colloidal platinum nanoparticles 显示文摘 | T S Ahmadi Z L Wang T C Green A Henglein M A El- Sayed | 1996 | Science1996，272，： | 1 |
| 13 | Multi-input multi-output fading channel tracking and equalization using Kalman estimation 显示文摘 | Komninakis C Fragouli C Sayed A H | 2002 | IEEE Transactions on Signal Processing2002，50，5： | 1 |
| 14 | Short communication expansion of cavities in layered elastic system显示文摘 | Sayed S M Hamed M A | 1987 | Intenational Journal for Numerical and Analytical Methods in Geomechanics1987，，1： | 1 |
| 15 | A feedback approach to the steady-state performance of fractionally fractionally spaced blind ada- ptive equalizers显示文摘 | J Mai A H Sayed | 2000 | IEEE Transactions on Signal Process- ing2000，48，1： | 1 |
| 16 | Effect of carbon nanotubes content on the mechanical of CNT-re- inforced aluminium composities 显示文摘 | EASWI A M K MORSI K SAYED A | 2010 | Composites Science and Technology2010，70，16： | 1 |
| 17 | The role of fringing coral reef in beach protection of Hurghada, Gulf of Suez, Red Sea of Egypt显示文摘 | Frihy O E El Ganaini M A El Sayed W R | 2004 | Ecological Engineering2004，22，1： | 1 |
| 18 | Au nanoparticles target cancer显示文摘 | Jain P K El - Sayed I H and El - Sayed M A | 2007 | Nano Today2007，2，1： | 1 |
| 19 | Deep neck space Abscesses显示文摘 | Dousary A L | 1996 | J Otolaryngol1996，25，4： | 1 |
| 20 | Adaptive tracking of linear time-variant systems by extended RLS algorithms显示文摘 | Haykin S Sayed A H Zeidler J R | 1997 | IEEE Transactions on Signal Processing1997，45，5： | 1 |
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