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| 1 | Intranasal ketamine for the treatment of patients with acute pain in the emergency department显示文摘BACKGROUND:Pain in the emergency department(ED)is common but undertreated.The objective of this study was to examine the efficacy and safety of intranasal(IN)ketamine used as an analgesic for patients with acute injury with moderate to severe pain.METHODS:This study was a cross sectional,observational study of patients more than 8 years old experiencing moderate to severe pain[visual analog score(VAS)>50 mm].The initial dose of IN ketamine was 0.7 mg/kg with an additional dose of 0.3 mg/kg if VAS was more than 50 mm after 15minutes.Pain scores and vital signs were recorded at 0,15,30 and 60 minutes.Side-effects,sedation level and patient's satisfaction were also recorded.The primary outcome was the number of patients achieving≥20 mm reductions in VAS at 15 minutes.Other secondary outcome measures were median reduction in VAS at 15,30 and 60 minutes,changes of vital signs,adverse events,satisfaction of patients,and need for additional ketamine.RESULTS:Thirty-four patients with a median age of 29.5 years(IQR 17.5–38)were enrolled,and they had an initial median VAS of 80 mm(IQR 67–90).The VAS decreased more than 20 mm at15 minutes in 27(80%)patients.The reduction of VAS from baseline to 40 mm(IQR 20–40),20 mm(IQR 14–20)and 20 mm(IQR 10–20)respectively at 15,30 and 60 minutes(P<0.001).No critical changes of vital signs were noted and adverse effects were mild and transient.CONCLUSION:This study showed that IN ketamine is an analgesic choice for patients with acute injury in moderate to severe pain in an overcrowded and resource limited ED. | Roshana Shrestha Samita Pant Ashis Shrestha Kabita Hada Batajoo Rashmi Thapa Sumana Vaidya | 2016 | World Journal of Emergency Medicine2016，7，1： | 2 |
| 2 | Interaction of BSA with proavin:A spectroscopic approach显示文摘 | Brotati Chakraborty Samita Basu | 2009 | Journal of Luminescence2009，129，： | 1 |
| 3 | Quantitative ex-pression of osteopontin in nasal mucosa of patients with allergic rhi-nitis :effects of pollen exposure and nasal glucocorticoid treatment显示文摘 | O’NEIL S E MALMHALL C SAMITAS K | 2010 | Allergy Asthma and Clinical Immunology2010，6，1： | 1 |
| 4 | Primary pleural epithelioid mesothelioma of clear cell type: a case report and review of cur- rent literature显示文摘 | Gkogkou C Samitas K Foteinou M | 2011 | Ultrastruct Pathol2011，35，6： | 1 |
| 5 | Tumor-derived CD4 + CD25 + regulatory T cell suppression of dendritic cell function involves TGF- β and IL-10显示文摘 | Nicolas Larmonier Marilyn Marron Yi Zeng Jessica Cantrell Angela Romanoski Marjan Sepassi Sylvia Thompson Xinchun Chen Samita Andreansky Emmanuel Katsanis | 2006 | Cancer Immunology, Immunotherapy2006，，1： | 1 |
| 6 | Accounting for spatial var-iability in field experim ents on tea Experim ental显示文摘 | PEIRIS T U S SAMITA S VERONICA W H D | 2008 | Agriculture2008，44，4： | 1 |
| 7 | Financial crises and stock market contagion in a multivariate time-varying asymmetric framework显示文摘 | Dimitris Kenourgios Aristeidis Samitas Nikos Paltalidis | 2010 | Journal of International Financial Markets, Institutions & Money2010，，1： | 1 |
| 8 | Extranodal natural killer/T-cell lymphoma,nasal-type case study显示文摘 | Chorianopoulos'D Samitas K Vittorakis S | 2010 | Skinned2010，，： | 1 |
| 9 | Exhaled Cysteinyl Leukotrienes and 8-isoprostane in Patients with Asthma and their Relation to Clinical Severity显示文摘 | Samitas K Chorianopoulos D Vittorakis S | 2009 | Respir Med2009，103，5： | 1 |
| 10 | Exhaled cysteinylleukotrienes and 8-isoprostane in patients with asthma and their relation to clinical severity显示文摘 | Samitas K Chorianopoulos D Vittorakis S | 2009 | Rsepir Med2009，103，5： | 1 |
| 11 | Letterto the editor-osteopontin levels in human asthma 显示文摘 | SAMITAS K ZERVAS E PANOUTSAKOPOULOU V | 2011 | The Journalof international medical research2011，39，6： | 1 |
| 12 | Inhaled eorticoste-roids in COPD : pros and cons显示文摘 | Zervas E Samitas K Gaga M | 2013 | Curt Drug Targets2013，14，2： | 1 |
| 13 | Exhaled eysteinyl-leukotrienes and 8- isoprostane in patients with asthma and their relation to clinical severity显示文摘 | Samitas K Chorianopoulos D Vittorakis S | 2009 | Respir Med2009，103，5： | 1 |
| 14 | Local recurrence of rectal cancer in patients not receiving neoadjuvant therapy-the importance of resection margins显示文摘 | Dassanayake BK Samita S Deen RY | | 0，，04： | 1 |
| 15 | Tumor-derived CD4+CD25+ regulatory T cell suppression of dendritic cell function involves TGF-β and IL-10显示文摘 | Nicolas Larmonier Marilyn Marron Yi Zeng Jessica Cantrell Angela Romanoski Marjan Sepassi Sylvia Thompson Xinchun Chen Samita Andreansky Emmanuel Katsanis | 2007 | Cancer Immunology Immunotherapy2007，，1： | 1 |
| 16 | Exhaled cysteinyl - leukotrienes and 8 - isoprostane in patients with asthma and their rela- tion to clinical severity 显示文摘 | Samitas K Chofianopoulos D Vittorakis S | 2009 | Rsepir Med2009，103，5： | 1 |
| 17 | A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the estimation of rivastigmine in human plasma显示文摘 | Jignesh Bhatt Gunta Subbaiah Sandeep Kambli Bhavin Shah Samita Nigam Mehul Patel Ashish Saxena Ashok Baliga Hetal Parekh Gunvat Yadav | 2007 | Journal of Chromatography B2007，，： | 1 |
| 18 | Exhaled cysteinyl - leukotrienes and 8 - isoprostane in patients with asthma and their rela- tion to clinical severity 显示文摘 | Samitas K Chorianopoulos D Vittorakis S | 2009 | Respir Med2009，103，5： | 1 |
| 19 | Financial crises and stock market contagion in a multivariate time-varying asymmetric framework显示文摘 | Dimitris Kenourgios Aristeidis Samitas Nikos Paltalidis | 2010 | Journal of International Financial Markets Institutions & Money2010，，1： | 1 |
| 20 | Pathogenesis of HongKong H5N1 influenza virus NS gene reassortants in mice: the roleofeytokines and B-and T-cell responses显示文摘 | Aleksandr SL Samita A Richard JW | 2005 | Journal of General Virology2005，86，： | 1 |
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