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| 1 | Autophagy is required for self-renewal and differentiation of adult human stem cells显示文摘 | Souzan Salemi Shida Yousefi Mihai A Constantinescu Martin F Fey Hans-Uwe Simon | 2012 | Cell Research2012,22,2: | 17 |
| 2 | High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS显示文摘Highly active antiretroviral treatment(HAART) has had a significant impact on survival of individuals with acquired immunodeficiency syndrome(AIDS);however,with the longer life-span of patients with AIDS,there is increasing prevalence of AIDS dementia complex(ADC) and other non-AIDS-defining illness,and cardiovascular diseases(CVD) are also common.The influence of these varied disease processes on HIV-1 DNA concentration in brain tissues has not been thoroughly assessed in the post-HAART era.The purpose of the current study is to clarify the impacts of ADC and other complications of HIV disease on the viral load in the brains in AIDS patients with post-HARRT.We examined autopsy specimens from the brains of thirteen patients who died from complications of AIDS with quantitative polymerase chain reaction(QPCR).All but one patient had received HAART prior to death since 1995.Two patients died with severe CVD,multiple cerebrovascular atherosclerosis(CVA) throughout the brain and five patients died with ADC.Six patients had no ADC/CVA.A QPCR was used to measure the presence of HIV-1 DNA in six brain tissues(meninges,frontal grey matter,frontal white matter,temporal subcortex,cerebellum and basal ganglia).In the post-HARRT era,for non-ADC/CVA patients,HIV-1 DNA concentration in brain tissues was statistically higher than that in patients with ADC.In a new finding,two patients who suffered from severe CVD,especially CVA,also had high concentrations of HIV-1 in brain compartments not showing ADC related changes.To our knowledge,this is the first report of a relationship between the CVA and HIV-1 viral burden in brain.The current observations suggest that HAART-resistant HIV reservoirs may survive within ADC lesions of the brain as well as the macrophage rich atherosclerosis,which needs to be confirmed by more AIDS cases with CVA. | GALLIGAN Derek C. LAMERS Susanna L. YU Stephanie SHAGRUN Lamia SALEMI Marco MCGRATH Michael S. | 2009 | Science China(Life Sciences)2009,52,7: | 3 |
| 3 | Epidemiological network analysis in HIV-1 B infected patients diagnosed in Italy between 2000 and 2008显示文摘 | Annapaola Callegaro Valentina Svicher Claudia Alteri Alessandra Lo Presti Daniela Valenti Antonio Goglio Marco Salemi Eleonora Cella Carlo Federico Perno Massimo Ciccozzi Franco Maggiolo | 2011 | Infection, Genetics and Evolution2011,,3: | 2 |
| 4 | Gallbladder cancer显示文摘 | Stavros Gourgiotis Hemant M. Kocher Leonardo Solaini Arvin Yarollahi Evangelos Tsiambas Nikolaos S. Salemis | 2008 | The American Journal of Surgery2008,,2: | 2 |
| 5 | Reconstruction of the evolutionary dynamics of the hepatitis C virus 1b epidemic in Turkey显示文摘 | Massimo Ciccozzi Anna-Rita Ciccaglione Alessandra Lo Presti Tulay Yalcinkaya Zeynep Pinar Taskan Michele Equestre Angela Costantino Roberto Bruni Erica Ebranati Marco Salemi Rebecca Gray Giovanni Rezza Massimo Galli Gianguglielmo Zehender | 2011 | Infection, Genetics and Evolution2011,,: | 2 |
| 6 | Modular self-reeonfigurable robot systems-challenges and opportunities for the future 显示文摘 | Yim M Shen W Salemi B | 2007 | IEEE Ro- botics and Automation Magazine2007,14,1: | 1 |
| 7 | Assessment of diastolic function in endomyocardial fibrosis: value of flow propagation velocity显示文摘 | SALEMI V M C PICARD M H MADY C | 2004 | Artificial Organs2004,28,4: | 1 |
| 8 | Detection of kappa and delta opioid receptors in skin-outside the nervous system显示文摘 | Salemi S Aesehlimann A Reiseh N | 2005 | Biochem Biophys Res Commun2005,338,2: | 1 |
| 9 | Diabetic and non-dia- betic subjects with ischemic stroke: differences, subtype distribution and outcomc显示文摘 | Tuttolomondo A Pinto A Salemi G | 2008 | Nutr Metab Cardiovasc Dis2008,18,2: | 1 |
| 10 | A novel FIP1LI-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome显示文摘 | Salemi S Yousefi S Simon D | 2009 | Allergy2009,64,6: | 1 |
| 11 | Reduced longevity in untreated patients with isolated growth hormone deficiency显示文摘 | Besson A Salemi S Gallati S | 2003 | Clin Endocrinol Metab2003,88,8: | 1 |
| 12 | Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT 显示文摘 | Handolias D Hamilton AL Salemi R | 2010 | Br J Cancer2010,102,8: | 1 |
| 13 | An index of substitution saturation and its application显示文摘 | Xia X Xie Z Salemi M etal | 2003 | Mol Phylogenet Evol2003,26,1: | 1 |
| 14 | Diabetic and non-diabetic subjects with ischemic stroke: differences, subtype distribution and outcome显示文摘 | Tuttolomondo A Pinto A Salemi G | 2008 | Nutr Metab Cardi- ovasc Dis [J]2008,18,2: | 1 |
| 15 | Diagnosis of simulated condylar bone defects using panoramic radiography,spiral tomography and cone-beam computed tomography:A comparison study显示文摘 | Salemi F Shokri A Mortazavi H | 2015 | J Clin Exp Dent2015,7,1: | 1 |
| 16 | Dynamic centrifuge model tests on asphalt-concrete core dams显示文摘 | Salemi S H Baziar M H Merrifield C M | 2009 | Géotechnique2009,59,9: | 1 |
| 17 | Modular selfreconfigurable robot systems 显示文摘 | Yim M Shen W M Salemi B | 2007 | IEEE Robotics & Automation Magazine2007,3,: | 1 |
| 18 | Hormone-inspired adaptive communication and distributed control for CONRO self-reconfigurable robots 显示文摘 | SHEN W M SALEMI B WILL P | 2002 | IEEE Transactions on Robotics and Automation2002,8,5: | 1 |
| 19 | Homocysteine thiolactone induces cardiac dysfunction :role of oxidative stress显示文摘 | Mendes RH Sirvente RA Candido GO Mostarda C Salemi VM D' Almeida V | 2010 | J Cardiovasc Pharma- col2010,55,2: | 1 |
| 20 | Prevalence of cervi- cal spondyiotic radiculopathy : a door - to - door survey in a Si- cilian municipality 显示文摘 | Salemi G Savettieri G Meneghini F | 1996 | Acta Neurol Scand1996,93,23: | 1 |