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| 1 | Review of renal cell carcinoma and its common subtypes in radiology显示文摘Representing 2%-3% of adult cancers, renal cell carcinoma(RCC) accounts for 90% of renal malignancies and is the most lethal neoplasm of the urologic system. Over the last 65 years, the incidence of RCC has increased at a rate of 2% per year. The increased incidence is at least partly due to improved tumor detection secondary to greater availability of high-resolution cross-sectional imaging modalities over the last few decades. Most RCCs are asymptomatic at discovery and are detected as unexpected findings on imaging performed for unrelated clinical indications. The 2004 World Health Organization Classification of adult renal tumors stratifies RCC into several distinct histologic subtypes of which clear cell, papillary and chromophobe tumors account for 70%, 10%-15%, and 5%, respectively. Knowledge of the RCC subtype is important because the various subtypes are associated with different biologic behavior, prognosis and treatment options. Furthermore, the common RCC subtypes can often be discriminated non-invasively based on gross morphologic imaging appearances, signal intensity on T2-weighted magnetic resonance images, and the degree of tumor enhancement on dynamic contrast-enhanced computed tomography or magnetic resonance imaging examinations. In this article, we review the incidence and survival data, risk factors, clinical and biochemical findings, imaging findings, staging, differential diagnosis, management options and posttreatment follow-up of RCC, with attention focused on the common subtypes. | Gavin Low Guan Huang Winnie Fu Zaahir Moloo Safwat Girgis | 2016 | World Journal of Radiology2016，8，5： | 20 |
| 2 | Molecular detection of monocyte chemotactic protein-1 polymorphism in spontaneous bacterial peritonitis patients显示文摘AIM: To investigate the association of the functional monocyte chemotactic protein-1(MCP-1) promoter polymorphism(A-2518G) with spontaneous bacterial peritonitis(SBP).METHODS: Fifty patients with post-hepatitis C liver cirrhosis and ascites were categorized into two groups; group Ⅰ included 25 patients with SBP and group Ⅱ included 25 patients free from SBP. In addition, a group of 20 healthy volunteers were included. We assessed the MCP-1 gene polymorphism and gene expression as well as interleukin(IL)-10 levels in both blood and ascitic fluid. RESULTS: A significant MCP-1 gene polymorphism was detected in groups Ⅰ and Ⅱ(P = 0.001 and 0.02 respectively). Group Ⅰ was associated with a significantly higher frequency of AG genotype [control 8(40%) vs SBP 19(76.0%), P < 0.001], and group Ⅱ was associated with a significantly higher frequency of GG genotype when compared to healthy volunteers [control 1(5%) vs cirrhotic 16(64%), P < 0.001]. Accordingly, the frequency of G allele was significantly higher in both groups(Ⅰ and Ⅱ) [control 10(25%) vs SBP 27(54%), P < 0.001 and vs cirrhotic 37(74.0%), P < 0.001, respectively]. The total blood and ascetic fluid levels of IL-10 and MCP-1 gene expression were significantly higher in group Ⅰ than in group Ⅱ. Group Ⅰ showed significant reductions in the levels of MCP-1 gene expression and IL-10 in the whole blood and ascetic fluid after therapy. CONCLUSION: MCP-1 GG genotype and G allele may predispose HCV infected patients to a more progressive disease course, while AG genotype may increase the susceptibility to SBP. Patients carrying these genotypes should be under supervision to prevent or restrict further complications. | Maysa Kamal Salama Dina Sabry Mohamed AS Al-Ghussein Rasha Ahmed Sayed AbdAllah Fatma Mohamed Taha Wael Fathy Miriam Safwat Wadie Mona Nabih Amr Abul-Fotouh Tarneem Darwish | 2014 | World Journal of Gastroenterology2014，20，33： | 7 |
| 3 | 日粮中添加银合欢叶粉或辣木叶粉对生长兔生长性能、胴体性状及经济效益的影响显示文摘试验旨在研究以银合欢(Leucaena leucocephala)叶粉(LLM)或辣木(Moringa oleifera)叶粉(MOLM)作为日粮主要来源对生长兔生长性能、胴体性状和经济效益的影响。60只加利福尼亚生长兔随机分为5组,即对照组、30%LLM组、40%LLM组、30%MOLM组和40%MOLM组,每组包括12只兔。试验从6周龄开始至12周龄结束。结果表明,对照组和30%MOLM组可显著提高生长兔终末体重和日增重(P<0.05),分别提高2040、2000g和31.6、30.6g/d;30%MOLM组和对照组料重比最低,分别为3.2和3.4,40%LLM组料重比最高,为5.2。与对照组相比,MOLM组可显著提高生长兔屠宰率(P<0.05)。与对照组(1.1元)相比,30%MOLM组和40%MOLM组可分别增加经济效益2.0和1.5元。综上所述,生长兔日粮中添加MOLM至40%时未对其生长性能、胴体性状及经济效益产生任何不利影响。 | Safwat A M 武江利 | 2014 | 中国畜牧兽医2014，41，8： | 3 |
| 4 | Structural and Tectonic Evolution of El-Faiyum Depression,North Western Desert,Egypt Based on Analysis of Landsat ETM+,and SRTM Data显示文摘False color Landsat ETM+ (bands 7, 4, 2 in RGB) and SRTM images of the El-Faiyum depression, Egypt, highlights major NE-SW faults and other lineaments trending NW-SE and N-S. Airborne magnetic data reveal some E-W subsurface faults which are not recognized on Landsat ETM+ and SRTM images. Ratio images (5/7, 3/1, 4/3) and (5/7, 5/1, 4) were used for lithological discrimination of different rock types. The El-Faiyum area is occupied by sedimentary rocks of Middle Eocene, Upper Eocene, Oligocene, Lower Miocene, Pliocene, Pleistocene and Holocene. Understanding the structural regime of El-Faiyum depression in the Western Desert of Egypt is significant in relation to the neotectonics of the Nile Delta and to the development of new communities west of the delta. The area is covered by Late Cretaceous, Middle to Late Eocene deposits, Oligocene deposits (comprising fluviatile sediments and basalt sheets) and Pliocene and Quaternary alluvium and sand deposits. New geological and structural maps were prepared at a scale of 1 : 100 000 using Landsat ETM+ and SRTM images coupled with extensive field work. The major structural trends are E-W, ENE, NS and NW-the same trends observed elsewhere in North Africa from NW Sudan to NE Egypt including north and central Sinai. El-Faiyum depression is a structurally-controlled tectonic basin, marked by northeast-striking faults along its northern margin. These faults are parallel to similar faults of the Syrian arc fold belt, which includes a group of related faults, folds, push-up structures, and basins. Qarun Lake is located in the northern part of El-Faiyum depression, at a right-step between two strands of the NE striking fault system. We have suggested elsewhere that El-Faiyum depression is a pull-apart basin related to extension between these mismatched strands of strike-slip faults. The E-W structures are probably related to the relative motion between south Europe and north Egypt and closure of the Neotethys. The continuation of these faults in the present area is only detected from magnetic and seismic studies. The question that needs to be raised is why these old structural features have been reactivated in recent times. Thus, the presence of these fault zones must be heeded in all development plans for El-Faiyum region. | Timothy M Kusky Talaat M Ramadan Mahmoud M Hassaan Safwat Gabr | 2011 | Journal of Earth Science2011，22，1： | 3 |
| 5 | The potential palliative role and possible immune modulatory effects of low-dose total body irradiation in relapsed or chemo-resis- tant non-Hodgkin's lymphoma显示文摘 | Safwat A Bayoumy Y E1-Sharkawy N | 2003 | Radiother Oncol2003，69，1： | 1 |
| 6 | Impairment of cardiac performance by laparoscopy in patients receiving positive end-expiratory pressure显示文摘 | Kraut EJ Anderson JT Safwat A | 1999 | Arch Surg1999，134，1： | 1 |
| 7 | Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance显示文摘 | D' Andrea FP Safwat A Kassem M | 2011 | Radiother On- col2011，99，3： | 1 |
| 8 | Detecting areas of high-potential gold mineralization using ASTER data显示文摘 | Safwat Gabr Abduwasit Ghulam Timothy Kusky | 2010 | Ore Geology Reviews2010，38，： | 1 |
| 9 | The Value of Serum Midkine Level in Diagnosis of Hepatocellular Carcinoma显示文摘 | Karim Y. A. Shaheen Abeer I. Abdel-Mageed Eslam Safwat Ashraf M. AlBreedy Shigeru Marubashi | 2015 | International Journal of Hepatology2015，，： | 1 |
| 10 | Tumour burden and interleukin-2 dose affect the interaction between low-dose total body irradiation and interleukin 2显示文摘 | Safwat A Aggerholm N Roitt I | 2004 | European Journal of Cancer2004，40，9： | 1 |
| 11 | Endobronchial ultra- sound-directed transbronchial needle aspiration in diagnosis of me- diastinal lesions : Initial egyptian experience 显示文摘 | Safwat T Khattab A EL Haddad S | 2009 | J Bronchol Inter- vent Pulmonol2009，16，1： | 1 |
| 12 | Diagnostic Criteria for Eosinophilic Esophagitis: A 5-year Retrospective Review in a Pediatric Population显示文摘 | Anita L Lai Safwat Girgis Yuanyuan Liang Stuart Carr Hien Q Huynh | 2009 | Journal of Pediatric Gastroenterology and Nutrition2009，，1： | 1 |
| 13 | Hepatic VLDL assembly isdisturbed in a rat model of nonalcoholic fatty liver disease : is therea role for dietary coenzyme Q 显示文摘 | Cano A Ciaffoni F Safwat GM | 2009 | J Appl Physiol2009，107，3： | 1 |
| 14 | Effects of preparation conditions on the monodispersity of albumin microspheres 显示文摘 | Ibrahim E - S Safwat S | 1998 | Journal of Microencapsulation1998，15，5： | 1 |
| 15 | N- Bromosuccinimide in the analysis of the terminal acetylenic unctional group显示文摘 | Safwat H M Hassib S T EI-Bagry R | 1991 | Egypt J Pharm Sci1991，32，12： | 1 |
| 16 | The immunobiology of low-dose total-body irradiation: more question than answers显示文摘 | Safwat A | 2000 | Radiat Res2000，153，： | 1 |
| 17 | Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance 显示文摘 | D'Andrea F P Safwat A Kassem M | 2011 | Radiother Oncol2011，99，： | 1 |
| 18 | 甘油酯对辛伐他汀纳米结构脂质载体性质、体外细胞摄取和细胞毒性的影响显示文摘考察了聚乙二醇(PEG)/甘油酯在研发纳米结构脂质载体(NLCs)中的适用性。采用具有不同亲水亲油平衡(HLB)值的PEG/甘油酯(Labrafil M 1944CS和Labrasol)以及不含PEG的甘油酯(Labrafac lipophile)为载体,制备辛伐他汀(SV)的NLCs,并考察其对MCF-7乳腺癌细胞潜在的抗肿瘤作用。 | Safwat S 王盈 | 2017 | 中国医药工业杂志2017，48，6： | 1 |
| 19 | Effects of progressive myocardial ischemia on systolic function,diastolic dyfunction and load-dependent relaxation显示文摘 | Leone BJ Norris RM Safwat A | 1992 | Cardiovasc Res1992，26，2： | 1 |
| 20 | Virtual base stations for wireless mobile ad hoc communications:An infrastructure for the infrastructure-less显示文摘 | Hassanein H S Safwat A M | 2001 | International Journal of Communication Systems2001，14，8： | 1 |
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