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| 1 | Molecular detection of monocyte chemotactic protein-1 polymorphism in spontaneous bacterial peritonitis patients显示文摘AIM: To investigate the association of the functional monocyte chemotactic protein-1(MCP-1) promoter polymorphism(A-2518G) with spontaneous bacterial peritonitis(SBP).METHODS: Fifty patients with post-hepatitis C liver cirrhosis and ascites were categorized into two groups; group Ⅰ included 25 patients with SBP and group Ⅱ included 25 patients free from SBP. In addition, a group of 20 healthy volunteers were included. We assessed the MCP-1 gene polymorphism and gene expression as well as interleukin(IL)-10 levels in both blood and ascitic fluid. RESULTS: A significant MCP-1 gene polymorphism was detected in groups Ⅰ and Ⅱ(P = 0.001 and 0.02 respectively). Group Ⅰ was associated with a significantly higher frequency of AG genotype [control 8(40%) vs SBP 19(76.0%), P < 0.001], and group Ⅱ was associated with a significantly higher frequency of GG genotype when compared to healthy volunteers [control 1(5%) vs cirrhotic 16(64%), P < 0.001]. Accordingly, the frequency of G allele was significantly higher in both groups(Ⅰ and Ⅱ) [control 10(25%) vs SBP 27(54%), P < 0.001 and vs cirrhotic 37(74.0%), P < 0.001, respectively]. The total blood and ascetic fluid levels of IL-10 and MCP-1 gene expression were significantly higher in group Ⅰ than in group Ⅱ. Group Ⅰ showed significant reductions in the levels of MCP-1 gene expression and IL-10 in the whole blood and ascetic fluid after therapy. CONCLUSION: MCP-1 GG genotype and G allele may predispose HCV infected patients to a more progressive disease course, while AG genotype may increase the susceptibility to SBP. Patients carrying these genotypes should be under supervision to prevent or restrict further complications. | Maysa Kamal Salama Dina Sabry Mohamed AS Al-Ghussein Rasha Ahmed Sayed AbdAllah Fatma Mohamed Taha Wael Fathy Miriam Safwat Wadie Mona Nabih Amr Abul-Fotouh Tarneem Darwish | 2014 | World Journal of Gastroenterology2014，20，33： | 7 |
| 2 | Corrosion, passivation and breakdown of passivity of Al and Al–Cu alloys in gluconic acid solutions显示文摘 | Mohammed A. Amin Sayed S. Abd El Rehim Abdallah S. El-Lithy | 2010 | Electrochimica Acta2010，，20： | 1 |
| 3 | Seismic performance of high-rise buildings in selected regions in Saudi Arabia according to different seismic codes显示文摘The design code for each country is revised and updated based on an expected zone’s seismic intensities,geotechnical site classifications,structural systems,construction materials and methods of construction in order to provide more realistic considerations of seismic demand,seismic response,and seismic capacity.Based on the aforementioned provisions,structures designed according to different seismic codes may yield different performances for the same level of hazard.This study aims to investigate and compare the induced responses related to the earthquake-resistant design of reinforced concrete(RC)buildings according to the Saudi building code(SBC-301),American code(ASCE-7),uniform building code(UBC-97),and European code(EC-8).In order to account for the provision regarding the hazard specification and its effect on the induced seismic responses,four regions in the Kingdom of Saudi Arabia with different seismic levels are selected.The code provisions related to the specification of site classification and its effect on the induced design base shear are investigated as well.Significant differences are observed in the induced responses with the variation in seismic design codes for the considered seismic hazards and site classifications. | Sayed Mahmoud Mohamed Alsearheed Waleed Abdallah | 2021 | Earthquake Engineering and Engineering Vibration2021，20，1： | 1 |
| 4 | The Internet in EFL Teacher Education: Investigating the Possibilities and Challenges in a Pre-service Education Programme显示文摘 | Mahmoud Mohamcmad Sayed Abdallah | 2011 | Sino-US English Teaching2011，8，1： | 0 |
| 5 | Epidemiology,etiology,and outcomes of in-hospital cardiac arrest in Lebanon显示文摘BACKGROUND In-hospital cardiac arrest(IHCA)constitutes a significant cause of morbidity and mortality.As data is scarce in the Middle East and Lebanon,we devised this study to shed some light on it to better inform both hospitals and policymakers about the magnitude and quality of IHCA care in Lebanon.METHODS We analyzed retrospective data from 680 IHCA events at the American University of Beirut Medical Center between July 1,2016 and May 2,2019.Sociodemographic variables included age and sex,in addition to the comorbidities listed in the Charlson comorbidity index.IHCA event variables were day,event location,time from activation to arrival,initial cardiac rhythm,and the total number of IHCA events.We also looked at the months and years.We considered the return of spontaneous circulation(ROSC)and survival to discharge(StD)to be our outcomes of interest.RESULTS The incidence of IHCA was 6.58 per 1,000 hospital admissions(95%CI:6.09−7.08).Non-shockable rhythms were 90.7%of IHCAs.Most IHCA cases occurred in the closed units(87.9%)(intensive care unit,respiratory care unit,neurology care unit,and cardiology care unit)and on weekdays(76.5%).ROSC followed more than half the IHCA events(56%).However,only 5.4%of IHCA events achieved StD.Both ROSC and StD were higher in cases with a shockable rhythm.Survival outcomes were not significantly different between day,evening,and nightshifts.ROSC was not significantly different between weekdays and weekends;however,StD was higher in events that happened during weekdays than weekends(6.7%vs.1.9%,P=0.002).CONCLUSIONS The incidence of IHCA was high,and its outcomes were lower compared to other developed countries.Survival outcomes were better for patients who had a shockable rhythm and were similar between the time of day and days of the week.These findings may help inform hospitals and policymakers about the magnitude and quality of IHCA care in Lebanon. | Ahmed Eltarras Youssef Jalloul Ola Assaad Michael Bejjani Yara Yammine Nina Khatib Abdallah Rebeiz Mazen El Sayed Marwan Refaat | 2021 | Journal of Geriatric Cardiology2021，18，6： | 0 |
| 6 | Biliary fistula and late recurrence of liver hydatid cyst:Role of cystobiliary communication:A prospective multicenter study显示文摘BACKGROUND Hydatid cyst disease(HCD)is common in certain locations.Surgery is associated with postoperative biliary fistula(POBF)and recurrence.The primary aim of this study was to identify whether occult cysto-biliary communication(CBC)can predict recurrent HCD.The secondary aim was to assess the role of cystic fluid bilirubin and alkaline phosphatase(ALP)levels in predicting POBF and recurrent HCD.AIM To identify whether occult CBC can predict recurrent HCD.The secondary aim was to assess the role of cystic fluid bilirubin and ALP levels in predicting POBF and recurrent HCD.METHODS From September 2010 to September 2016,a prospective multicenter study was undertaken involving 244 patients with solitary primary superficial stage cystic echinococcosis 2 and cystic echinococcosis 3b HCD who underwent laparoscopic partial cystectomy with omentoplasty.Univariable logistic regression analysis assessed independent factors determining biliary complications and recurrence.RESULTS There was a highly statistically significant association(P≤0.001)between cystic fluid biochemical indices and the development of biliary complications(of 16 patients with POBF,15 patients had high cyst fluid bilirubin and ALP levels),where patients with high bilirubin-ALP levels were 3405 times more likely to have biliary complications.There was a highly statistically significant association(P≤0.001)between biliary complications,biochemical indices,and the occurrence of recurrent HCD(of 30 patients with recurrent HCD,15 patients had high cyst fluid bilirubin and ALP;all 16 patients who had POBF later developed recurrent HCD),where patients who developed biliary complications and high bilirubin-ALP were 244.6 and 214 times more likely to have recurrent hydatid cysts,respectively.CONCLUSION Occult CBC can predict recurrent HCD.Elevated cyst fluid bilirubin and ALP levels predicted POBF and recurrent HCD. | Tamer A A M Habeeb Mauro Podda Boris Tadic Vishal G Shelat Yaman Tokat Mohamed Ibrahim Abo Alsaad Abd-Elfattah Kalmoush Mohammed Shaaban Nassar Fawzy Metwally Mustafa Mahmoud Hassib Morsi Badawy Mohamed Sobhy Shaaban Tarek Zaghloul Mohamed Mohammed Ibrahim El Sayed Henish Hamdi Elbelkasi Mahmoud Abdou Yassin Abdelshafy Mostafa Amr Ibrahim Waleed A-Abdelhady TamerMohamed Elshahidy Mohamed Ibrahim Mansour Adel Mahmoud Moursi Mohamed Abdallah Zaitoun EhabShehata Abd-Allah Ashraf Abdelmonem Elsayed Rasha S Elsayed Ahmed M Yehia Amr Abdelghani Mohamed Negm Heba Alhussein Abo-Alella Mostafa M Elaidy | 2023 | World Journal of Methodology2023，13，4： | 0 |
| 7 | Predictors of graft function and survival in second kidney transplantation: A single center experience显示文摘BACKGROUND The increasing kidney retransplantation rate has created a parallel field of research,including the risk factors and outcomes of this advanced form of renal replacement therapy.The presentation of experiences from different kidney transplantation centers may help enrich the literature on kidney retransplantation,as a specific topic in the field of kidney transplantation.AIM To identify the risk factors affecting primary graft function and graft survival rates after second kidney transplantation(SKT).METHODS The records of SKT cases performed between January 1977 and December 2014 at a European tertiary-level kidney transplantation center were retrospectively reviewed and analyzed.Beside the descriptive characteristics,the survivals of patients and both the first and second grafts were described using Kaplan-Meier curves.In addition,Kaplan-Meier analyses were also used to estimate the survival probabilities at 1,3,5,and 10 post-operative years,as well as at the longest followup duration available.Moreover,bivariate associations between various predictors and the categorical outcomes were assessed,using the suitable biostatistical tests,according to the predictor type.RESULTS Out of 1861 cases of kidney transplantation,only 48 cases with SKT were eligible for studying,including 33 men and 15 women with a mean age of 42.1±13 years.The primary non-function(PNF)graft occurred in five patients(10.4%).In bivariate analyses,a high body mass index(P=0.009)and first graft loss due to acute rejection(P=0.025)were the only significant predictors of PNF graft.The second graft survival was reduced by delayed graft function in the first(P=0.008)and second(P<0.001)grafts.However,the effect of acute rejection within the first year after the first transplant did not reach the threshold of significance(P=0.053).The mean follow-up period was 59.8±48.6 mo.Censored graft/patient survival rates at 1,3,5 and 10 years were 90.5%/97.9%,79.9%/95.6%,73.7%/91.9%,and 51.6%/83.0%,respectively.CONCLUSION Non-immediate recovery modes of the first and second graft functions were significantly associated with unfavorable second graft survival rates.Patient and graft survival rates of SKT were similar to those of the first kidney transplantation. | Mahmoud Khalil Rabea Ahmed Gadelkareem Medhat Ahmed Abdallah Mohamed Abdel-Basir Sayed FathyGaber Elanany Paolo Fornara Nasreldin Mohammed | 2023 | World Journal of Transplantation2023，13，6： | 0 |
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