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| 1 | RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings显示文摘在有前列腺癌症的不同赛跑的病人之中有显著不同;然而,位于这差别下面的机制仍然保持不清楚。这里,我们在场 transcriptome 的一处全面风景用 RNA-seq,越过关于基因熔化的前列腺癌症 transcriptomes 的揭示巨大的差异,长 noncoding RNA (长 ncRNA ) ,其他的拼接和体的变化从中国人口 14 主要前列腺癌症和他们的配对的正常对应物介绍。14 个肿瘤(21.4%) 中的三个在中国病人怀有 TMPRSS2 尔格熔化,和这熔化的低流行进一步在一个另外的肿瘤集合(10/54=18.5%) 被证实。尤其是,二新奇基因熔化, CTAGE5-KHDRBS3 (20/54=37%) 和 USP9Y-TTTY15 (19/54=35.2%) ,在我们的耐心的队经常发生了。介绍的进一步系统的 transcriptional 识别了是在肿瘤表示的差别的众多的长 ncRNAs。在长 ncRNA 和基因的表示之间的关联的分析建议长 ncRNAs 可以在 transcriptional 规定以外有功能。这研究在中国人口产出新卓见进前列腺癌症的致病。 | Shancheng Ren Zhiyu Peng Jian-Hua Mao Yongwei Yu Changjun Yin Xin Gao Zilian Cui Jibin Zhang Kang Yi Weidong Xu Chao Chen Fubo Wang Xinwu Guo Ji Lu Jun Yang Min Wei Zhijian Tian Yinghui Guan Liang Tang Chuanliang Xu Linhui Wang Xu Gao Wei Tian Jian Wang Huanming Yang Jun Wang Yinghao Sun | 2012 | Cell Research2012，22，5： | 66 |
| 2 | Natural orifice transluminal endoscopic surgery in urology: The Chinese experience显示文摘Objective:To describe the Chinese experience of natural orifice transluminal endoscopic surgery(NOTES)in urology.Methods:From December 2008 to May 2017,35 animal experiments and 305 clinical surgeries of NOTES or natural orifices specimen extractions(NOSE)were performed in China.The animal experiments included five kidney biopsies,24 nephrectomies and six partial nephrectomies.The clinical surgeries included 12 transvaginal NOSE(TV-NOSE),266 hybrid transvaginal NOTES(TV-NOTES)and 27 pure TV-NOTES.The TV-NOSE procedure was performed in five transumbilical laparoendoscopic single-site(U-LESS)nephrectomies,four suprapubic-assisted laparoendoscopic single-site surgery(SA-LESS)nephroureterectomies,and three laparoscopic radical cystectomies.The hybrid TV-NOTES procedure included 210 nephrectomies,31 adrenalectomies,eight nephroureterectomies,13 partial nephrectomies,and four heminephrectomies.The pure TV-NOTES procedure included five renal cyst decortications and 22 nephrectomies.Results:A total of 29 animal experiments were successfully performed.One partial nephrectomy was converted to standard laparoscopic surgery.Two kidney biopsies and two nephrectomies were unsuccessful.A total of 297 clinical surgeries were successfully performed.Six patients who underwent hybrid TV-NOTES were converted to open surgery.Two patients who underwent pure TV-NOTES were converted to SA-LESS.There were 22 major complications,16 occurred intraoperatively and six postoperatively.The mean visual analog score(VAS)of 48 h after the operation was 2.5 points in TV-NOSE,2.3 points in hybrid TV-NOTES and 1.7 points in pure TV-NOTES.The mean follow-up of 50.6(3.0-87.0)months showed that all patients were in good condition.The umbilicus scars were nearly invisible in TV-NOSE and hybrid TV-NOTES.The vaginal incision healed well.Conclusions:TV-NOSE and TV-NOTES are feasible,safe,and effective with little injury,low pain,fast recovery,and good cosmetic outcomes in properly selected patients.They are worth consideration for urological clinical practice. | Xiaofeng Zou Guoxi Zhang Tianpeng Xie Yuanhu Yuan Rihai Xiao Gengqing Wu Xiaoning Wang Hui Xu Folin Liu Yuting Wu Yunfeng Liao Quanliang Liu Yinghao Sun Bo Yang Linhui Wang Chuanliang Xu Xiaofeng Gao | 2020 | Asian Journal of Urology2020，7，1： | 5 |
| 3 | Simplification of I-Vector Extraction for Speaker Identification显示文摘The identity vector(i-vector) approach has been the state-of-the-art for text-independent speaker recognition, both identification and verification in recent years. An i-vector is a low-dimensional vector in the socalled total variability space represented with a thin and tall rectangular matrix. This paper introduces a novel algorithm to improve the computational and memory requirements for the application. In our method, the series of symmetric matrices can be represented by diagonal expression,sharing the same dictionary, which to some extent is analogous to eigen decomposition, and we name this algorithm Eigen decomposition like factorization(EDLF). Similar algorithms are listed for comparison, in the same condition,our method shows no disadvantages in identification accuracy. | XU Longting YANG Zhen SUN Linhui | 2016 | Chinese Journal of Electronics2016，25，6： | 4 |
| 4 | Laparoscopic ureterolysis with simultaneous ureteroscopy and percutaneous nephroscopy for treating complex ureteral obstruction after failed endoscopic intervention:A technical report显示文摘Objective:Complex ureteral obstruction is refractory to conventional urological intervention.This report describes a case of laparoscopic ureterolysis with simultaneous ureteroscopy and percutaneous nephroscopy for treating complex ureteral obstruction.Methods:Right-side multiple ureteral stones and complicating ureteral obstruction failed an initial attempt of ureteroscopy lithotripsy with simultaneous percutaneous nephroscopy in a 23-year-old male.Laparoscopic ureterolysis with ureteroscopy and percutaneous nephroscopy was used simultaneously to dissect the periureteral adhesions with the patient placed in the Galdakao-modified supine Valdivia position.The ureter was incised to allow the insertion of a ureteral catheter through the twisted ureter,and a guide wire was advanced into the pelvis using ureteroscopy.A double-J stent was placed into the right-side ureter using antegrade percutaneous nephroscopy.Results:The laparoendoscopic procedure lasted 330 min with an estimated bleeding volume of 100 mL.The patient underwent an uneventful postoperative course,and postoperative followup radiography confirmed good positioning of the double-J stent.The double-J stent was removed 3 months after operation.The patient remained asymptomatic within a 13-month follow-up period.Conclusion:Laparoscopic ureterolysis with simultaneous ureteroscopy and percutaneous nephroscopy is an effective and safe treatment option for complex ureteral obstruction. | Zhixiang Wang Bing Liu Xiaofeng Gao Yi Bao Yang Wang Huamao Ye Yinghao Sun Linhui Wang | 2015 | Asian Journal of Urology2015，2，4： | 2 |
| 5 | Strong expression of chemokine receptor CXCR4 by renal cell carcinoma cells correlates with metastasis显示文摘 | Linhui Wang Liang Wang Bo Yang Qing Yang Shouyi Qiao Yingming Wang Yinghao Sun | 2009 | Clinical & Experimental Metastasis2009，，8： | 2 |
| 6 | CXCR4 nuclear localization follows binding of its ligand SDF-1 and occursin metastatic but not primary renal cell carcinoma显示文摘 | Linhui Wang Zhixiang Wang Bo Yang Qing Yang Liang Wang Yinghao Sun | 2009 | Oncology Reports2009，，6： | 1 |
| 7 | Pneumatic lithotripsy versus laser lithotripsy in the endoscopic treatment of ureteral calculi显示文摘 | Sun Yinghao Wang Linhui Liao Guoqiang | 2001 | Journal of Endourology2001，15，： | 1 |
| 8 | Silencing of CXCR4 by RNA interference inhibits cell growth and metastasisin human renal cancer cells显示文摘 | Linhui Wang Ting Huang Wei Chen Xiaofeng Gao Tie Zhou Zhenjie Wu Yinghao Sun | 2012 | Oncology Reports2012，，6： | 1 |
| 9 | Differentially ex- pressed genes under cold acclimation in Physcomitrella patens 显示文摘 | Sun Mingming Li Linhui Xie Hua | 2007 | Journal of Biochemistry and Molecular Biolo- gy2007，40，6： | 1 |
| 10 | Analysis of HK-2 cells exposed to oxalate and calcium oxalate crystals: proteomic insights into the molecular mechanisms of renal injury and stone formation显示文摘 | Shushang Chen Xiaofeng Gao Yinghao Sun Chuanliang Xu Linhui Wang Tie Zhou | 2010 | Urological Research2010，，1： | 1 |
| 11 | Silencing of CXCR4 by RNA interference inhibits cell growth and metastasisin human renal cancer cells显示文摘 | Linhui Wang Ting Huang Wei Chen Xiaofeng Gao Tie Zhou Zhenjie Wu Yinghao Sun | 2012 | Oncology Reports2012，，6： | 1 |
| 12 | Transumbilical laparoendoscopic single-site surgery of simple nephrectomy of nonfunctioning kidney: a two-year experience显示文摘Background: Laparoendoscopic single-site surgery (LESS) may serve as a potential alternative to conventional laparoscopy and is developing quickly, but still in its infancy. The study is to present our two-year experience in transumbilical LESS simple nephrectomy (LESS-SN) for non-functioning kidney, in an effort to evaluate its feasibility, clinical outcomes and potential advantages. Methods: From December 2008 to December 2010, a total of 11 patients with body mass index (BMI) ≤30 underwent transumbilical TriPort TM LESS-SN by a single experienced urologist at our institution. The indications for nephrectomy included nonfunctioning kidney associated with ureteropelvic junctionstricture (n=1), ureteral calculi (n=6), tuberculosis (n=3), and ureteral stricture (n=1). Patient demographics, perioperative and follow-up data were prospectively collected and analyzed. Results: Ten procedures were successfully completed with one patient converted to open surgery due to uncontrollable bleeding. The mean operative time was 189.2 (ranging 100~320 min) with an estimated blood loss of 204.5 (ranging 50-1 000 ml). There were two complications of bleeding (1- intra-, 1- post-). The mean hospitalization after surgery was 7.9 d (ranging 4-17 d). With a regular follow-up of 1, 6, 12, and 24 months after surgery, all patients remained symptom-free with an intra-umbilical scar. Conclusion: Transumbilical LESS simple nephrectomy for nonfunctioning kidney can be accomplished with favorable surgical outcomes and a superiority of cosmesis. However, cases with chronic inflammation are not suitable for initial up-take and should only be attempted by the very experienced laparoscopist. | Wang Linhui Wu Zhenjie Liu Bing Yang Qing Chen Wei Sheng Haibo Xu Zunli Wang Cheng Sun Yinghao | 2011 | Journal of Medical Colleges of PLA(China)2011，26，4： | 1 |
| 13 | Phytoplankton growth and microzooplankton grazing in the central and northern South China Sea in the spring intermonsoon season of 2017显示文摘Phytoplankton growth rates and mortality rates were experimentally examined at 21 stations during the 2017 spring intermonsoon(April to early May)in the northern and central South China Sea(SCS)using the dilution technique,with emphasis on a comparison between the northern and central SCS areas which had different environmental factors.There had been higher temperature but lower nutrients and chlorophyll a concentrations in the central SCS than those in the northern SCS.The mean rates of phytoplankton growth(μ0)and microzooplankton grazing(m)were(0.88±0.33)d–1 and(0.55±0.22)d–1 in the central SCS,and both higher than those in the northern SCS with the values ofμ0((0.81±0.16)d–1)and m((0.30±0.09)d–1),respectively.Phytoplankton growth and microzooplankton grazing rates were significantly coupled in both areas.The microzooplankton grazing impact(m/μ0)on phytoplankton was also higher in the central SCS(0.63±0.12)than that in the northern SCS(0.37±0.06).The microzooplankton abundance was significantly correlated with temperature in the surface.Temperature might more effectively promote the microzooplankton grazing rate than phytoplankton growth rate,which might contribute to higher m and m/μ0 in the central SCS.Compared with temperature,nutrients mainly affected the growth rate of phytoplankton.In the nutrient enrichment treatment,the phytoplankton growth rate(μn)was higher thanμ0 in the central SCS,suggesting phytoplankton growth in the central SCS was nutrient limited.The ratio ofμ0/μn was significantly correlated with nutrients concentrations in the both areas,indicating the limitation of nutrients was related to the concentrations of background nutrients in the study stations. | Dawei Chen Congcong Guo Linhui Yu Yuanzhen Lu Jun Sun | 2020 | Acta Oceanologica Sinica2020，39，6： | 0 |
| 14 | Preoperative diagnosis of renal oncocytoma: case report and literature review显示文摘To differentiate renal oncocytoma from renal carcinoma, the clinical data of four patients with incidentally found renal oncocytomas were studied in this report. And additional Immunohistochemistry examinations were done to confirm diagnosis. Renal oncocytomas were found incidentally in four patients during medical examination. No characteristic changes were found in laboratory tests. Radiology examination provided the location and possibility of renal oncocytoma. History, laboratory test and radiology exanimation indicated the diagnosis of renal oncocytoma, but the final identify of renal oncocytoma need pathology examination. | Wang Linhui Wang Zhixiang Sun Yinghao | 2008 | Journal of Medical Colleges of PLA(China)2008，23，5： | 0 |
| 15 | Huge pyogenic liver abscess(PLA)in an elderly patient with dia-betes following the pancreaticoduodenectomy显示文摘We described an elderly female with type 2 diabetes referred to our hospital with fever, nausea and upper abdominal pain. The patient had got duodenal tumor and received the pancreaticoduodenectomy(PD)12 years ago. The laboratory examinations revealed white blood cells(WBC)increasing and severe hypocalcemia. Abdominal computed tomography(CT)revealed a huge gas-forming pyogenic liver abscess(PLA)in left lobe of the liver. The patient got cured after correction of calcium metabolism disorders, treatment with antibiotic and receiving percutaneous tube drainage. We concluded that we should remain on high alert of those patients with DM and the history of cancer, when he or she gets fever of unknown origin and abdominal tenderness. PLA should be considered. | Liu Yunfeng Li Linhui Zhang Yi Xu Linxin Yin Jianhong Sun Li Yang Jing | 2019 | 中华内分泌外科杂志2019，13，3： | 0 |
| 16 | Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release. | Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou | 2023 | Research2023，，2： | 0 |
| 17 | Experimental study for frequency spectrum of turbulent boundary layer pressure fluctuation显示文摘An experimental study on TBL (turbulent boundary layer) pressure fluctuation frequeny spectrum of a revolution body is presented. With the measured results, a relation of convective frequency fo of the models is obtained. Relations of turbuleat wall-pressure fluctuation spectrum in transition region and development region to frequency and speed are obtained | PENG Linhui LU Jianhui (Ocean University of Qingdao Qingdao 266003) ZHU Xiqing SUN Yudong (CSSRC Wuxi 214082) | 1999 | Chinese Journal of Acoustics1999，18，3： | 0 |
| 18 | Duplicated inferior vena cava in a patient undergoing right transumbilical laparoendoscopic single-site (LESS) radical nephrectomy显示文摘LaparoEndoscopic Single-site(LESS) renal surgery emerging as a potential alternative to conventional laparoscopy,is technically challenging and the major vascular anomaly may increase the risk of intraoperative haemorrhage.Herein,we present a case of right transumbilical LESS radical nephrectomy which was successfully performed in the presence of double inferior vena cava and duplicated the standard laparoscopic techniques.Most importantly,to bring such an aberrant vascular anatomy to the attention of laparoscopic,especially LESS surgeons with high resolution pictorial illustrations. | Wang Linhui Wu Zhenjie Liu Bing Yang Qing Sun Yinghao | 2011 | Journal of Medical Colleges of PLA(China)2011，26，5： | 0 |
| 19 | Transumbilical laparoendoscopic single-site surgery(LESS) partial nephrectomy:a median follow-up of 2 years显示文摘Objective:Nephron-sparing surgery(NSS) for small renal masses offers a similar functional and oncological outcome to that of radical surgery.Laparoendoscopic single-site surgery(LESS) emerges as an advanced alternative for reduced invasiveness and improves cosmesis;LESS is developing quickly and its indications have been expanded,but still in its infancy.The aim of this paper is to report our preliminary experience in transumbilical LESS partial nephrectomy(LESS-PN),so as to assess its utility, safety and efficacy.Methods:From August 2009 to October 2010,3 patients underwent transumbilical LESS-PN via a novel multi-channel TriPort by a single experienced urologist in our institution.Patient demographics,perioperative and follow-up data were prospectively collected and analyzed.Results:All the three procedures were successfully completed.A 5-mm ancillary trocar was utilized in all 3 cases.The mean operative duration was 226.3(210-254 min) with an estimated blood loss of 56.7 ml (20-100 ml).Mean warm ischemia time was 35.7 min(19-48 min).One patient was transfused due to postoperative bleeding. The recovery was uneventful and mean length of postoperative stay was 13 days(12-14 days).At the latest follow-up,all patients remained symptom-free and had normal renal function without evidence of recurrence,and they were delighted for a hidden transumbilical scar.Conclusion:Transumbilical LESS-PN is a feasible and safe procedure albeit extremely technically challenging.Surgical outcomes at a median follow-up of 2 years are promising,while currently it should be reserved for highly selected patients with favorable tumor anatomy and performed by a very experienced laparoscopic surgeon. | Wang Linhui Wu Zhenjie Liu Bing Yang Qing Xiao Liang Sun Yinghao | 2011 | Journal of Medical Colleges of PLA(China)2011，26，6： | 0 |
| 20 | Synchronous bilateral laparoendoscopic single-site urological surgeries via the umbilicus:a report of 2 cases显示文摘Objective:To describe two cases of bilateral transumbilical laparoendoscopic single-site(LESS) surgeries in a single operative session and assess the safety,feasibility and efficacy.Methods:One patient underwent right ureterolithotomy and left varicocelectomy,and the patient was performed with right simple nephrectomy for nonfunctioning kidney due to ureteral calculus and left ureterolithotomy using a novel multichannel TriPort? via a single 2-3 cm transumbilical incision. Results:The right-side ureterolithotomy and left-side varicocelectomy were finished in 229 minutes,with a total estimated blood loss of 50 ml.The right-side simple nephrectomy and left-side ureterolithotomy in the other patient were finished in 340 minutes,with a total estimated blood loss of 100 ml.There were no major complications.At the latest follow-up,both patients remained symptom-free and there were no evidences of recurrence.Both of them were delighted for the single scar. Conclusion:Synchronous LESS urologic procedure via a single umbilical incision is technically feasible,safe and efficacious with a promising potential. | Wang Linhui Wu Zhenjie Liu Bing Yang Qing Sheng Haibo Chen Wei Xu Zunli Wang Cheng Sun Yinghao | 2011 | Journal of Medical Colleges of PLA(China)2011，26，6： | 0 |
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