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| 1 | Clinicopathological features of gastric glomus tumor显示文摘AIM:To study the clinicopathological features of gastric glomus tumor and review the related Chinese literature published in 1990-2010.METHODS:A case of gastric glomus tumor was re-ported.Clinicopathological findings in 56 cases of gastric glomus tumor were analyzed.RESULTS:Gastric glomus tumor was far more common in women than in men with a female to male ratio of 1.6:1.The median age of the patients was 45 years(range 28-79 years).The patients often complained of epigastric pain and bloody stool.The tumor was located in antrum of the stomach.The greatest diameter of the tumor was 0.8-11cm.Histologically,the tumor was comprised of nests of glomus cells surrounding the capillaries.Glomus cells were small,uniform and round.Vimentin,smooth muscle actin and actin were expressed in the tumor.Other markers,including S-100 protein,CD34,CD117,desmin,CD56,synaptophysin,chromo-granin A,neuron specific enolase and cytokeratin were all negative.CONCLUSION:Gastric glomus tumor is a rare benign mesenchymal neoplasm.Its diagnosis depends on pathologic examination.Differential diagnosis includes gastrointestinal stromal tumor,paraganglioma and carcinoid tumor. | Hui-Qiong Fang,Jing Yang,Fen-Fen Zhang,An-Jia Han,Department of Pathology,First Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510080,Guangdong Province,China Hui-Qiong Fang,Department of Pathology,Foshan Hospital of Traditional Chinese Medicine,Foshan 528000,Guangdong Province,China Jing Yang,Department of Pathology,People’s Hospital of Zhu-hai City,Zhuhai 519000,Guangdong Province,China Yi Cui,Department of Gastroenterology,First Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510080,Guangdong Province,China | 2010 | World Journal of Gastroenterology2010，16，36： | 28 |
| 2 | Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘 | Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 25 |
| 3 | Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells显示文摘Liver fibrosis is a consequence of chronic liver disease,causing morbidity and mortality.Interleukin-33(IL-33)is a critical mediator of inflammation,which may be involved in the development of liver fibrosis.Here,we investigated the role of IL-33 in human patients and experimental bile-duct ligation(BDL)-induced fibrosis in mice.We report increased hepatic IL-33 expression in the murine BDL model of fibrosis and in surgical samples obtained from patients with liver fibrosis.Liver injury,inflammatory cell infiltration and fibrosis were reduced in the absence of the IL-33/ST2 receptor,and the activation of hepatic stellate cells(HSCs)was decreased in ST2-deficient mice.Recombinant IL-33 activated HSCs isolated from C57BL/6 mice,leading to the expression of IL-6,TGF-β,α-SMA and collagen,which was abrogated in the absence of ST2 or by pharmacological inhibition of MAPK signaling.Finally,administration of recombinant IL-33 significantly increased hepatic inflammation in sham-operated BL6 mice but did not enhance BDL-induced hepatic inflammation and fibrosis.In conclusion,BDL-induced liver inflammation and fibrosis are dependent on ST2 signaling in HSCs,and therefore,the IL-33/ST2 pathway may be a potential therapeutic target in human patients with chronic hepatitis and liver fibrosis. | Zhongming Tan Qianghui Liu Runqiu Jiang Long Lv Siamak S Shoto Isabelle Maillet Valerie Quesniaux Junwei Tang Wenjie Zhang Beicheng Sun Bernhard Ryffel | 2018 | Cellular & Molecular Immunology2018，15，4： | 24 |
| 4 | Vasculogenic mimicry is a prognostic factor for postoperative survival in patients with glioblastoma显示文摘A previous report has confirmed the existence and clinical significance of vasculogenic mimicry(VM)in glioma.However,its conclusions about the negative clinical significance of VM in glioblastoma are based on a small group of patients and,thus,might be unconvincing.The aim of the present study was to reevaluate the clinical significance of VM in glioblastoma.Patients were classified as VM-positive or | Wang SY Ke YQ Lu GH Song ZH Yu L Xiao S Sun XL Jiang XD Yang ZL Hu CC | 2013 | 中国神经肿瘤杂志2013，11，3： | 22 |
| 5 | 裂缝性油气藏采收率:100个裂缝性油气田实例的经验总结(英文)显示文摘通过对世界上100个裂缝性油气藏的综合评价,研究储集层及流体本身的性质(包括孔隙度、渗透率、黏度、可动油比例、含水饱和度、润湿性及裂缝分布特征等)和驱动机制及油藏管理战略(优化日产量和采用不同类型的提高采收率技术)对其最终采收率的影响。将裂缝性油气藏分为4类:Ⅰ类的基质几乎没有孔隙度和渗透率,裂缝是储存空间和流体流动的通道;Ⅱ类的基质有较低的孔隙度和渗透率,基质提供储存空间,裂缝提供流动通道;Ⅲ类(微孔隙)的基质具有高孔隙度和低渗透率,基质提供储存空间,裂缝提供流动通道;Ⅳ类(大孔隙)的基质具有高的孔隙度和渗透率,基质提供储存空间和流动通道,裂缝仅增加渗透率。对26个Ⅱ类油气藏和20个Ⅲ类油气藏的开采历史的研究表明:Ⅱ类油气藏的采收率受水驱强度和最优日产量控制,日产量过高会很容易破坏Ⅱ类油气藏,一些Ⅱ类油气藏如果管理得当,采收率可以很高,不需要二次或三次采油;Ⅲ类油气藏的采收率主要受岩石和流体本身性质的影响,特别是基质渗透率、流体重度、润湿性以及裂缝强度等,不进行二次或三次采油不可能完全开采,往往需要采用一些提高采收率的专门技术。以往将Ⅱ类和Ⅲ类裂缝性油气藏归为一类,认识它们的区别将有助于选择更好的开发策略。 | Jack Allan S Qing Sun | 2003 | 石油勘探与开发2003，30，6： | 17 |
| 6 | 1997年全国艾滋病哨点监测报告显示文摘1997年,全国HIV监测哨点共调整为60个,分布在27个省(自治区、直辖市)。性病门诊哨点和长卡哨点中只检出极少数HIV感染者。1997年,在3个暗娼哨点中的检出率约为1%~2%,而1996年同期仅为不到0.5%;在12个吸毒哨点中有7个哨点(包括2个新增哨点)报告了HIV感染者,而在1996年同期8个哨点中有3个哨点报告了感染者。新疆自治区报告了83例(20.8%)感染者,而在前几年同期同一哨点只有32例(8.0%)。在大部分吸毒监测哨点中的静注比例正不断增加或保持一个较高水平。暗娼人群中有60%从不使用避孕套。该监测结果表明,局部地区吸毒者中HIV感染率在不断上升,HIV波及的地区在不断地增多,HIV感染已开始向性乱人群扩散;可引起HIV流行的危险因素在不断增加。 | Department of Disease Control,Ministry of Health,People′s Republic of China 1 Center for AIDS Surveillance,Chinese Academy of Preventive Medicine 2 Group of National HIV Sentinel Surveillance Program (Written by Qu Shuquan 2,Sun Xinhua 1,Zheng X | 1998 | 中国性病艾滋病防治1998，4，4： | 15 |
| 7 | 1996年中国艾滋病哨点监测报告显示文摘我国自1995年开始在23个省(自治区、直辖市)的42个哨点中对性传播疾病(STDs)门诊就诊者、暗娼、吸毒者和长途卡车司机四类人群进行监测,当年监测结果显示,在监测哨点所在的城市中,被监测的STDs门诊就诊者、暗娼、吸毒者和长途卡车司机人群中HIV感染率均很低,但存在广泛传播的危险性。1996年第一轮共监测10085人,发现HIV感染者35例。其中在STDs门诊就诊者中发现HIV感染者1例,在吸毒者中发现HIV感染者34例(其中新疆32例);第二轮监测11909人,发现HIV感染者72例,其中在暗娼人群中发现1例,在吸毒人群中发现71例(其中新疆69例)。1996年监测结果表明,在哨点所在的城市中,尽管被监测的STDs门诊就诊者、暗娼和长途卡车司机人群中HIV感染率仍很低,但我国HIV流行形势已发生改变,HIV感染的流行已不仅仅局限于云南吸毒者中,在其它地区已开始在吸毒者中流行,个别地区该人群中HIV感染率上升很快。 | Department of Disease control.Ministry of Health,People′s Republic of China 1 Center for AIDS Surveillance,Chinese Academy of Preventive Medicine 2 Group of National HIV sentinel surveillance program (Written by Qu Shuquan 2,Sun Xinhua 1,Zheng Xiwen | 1997 | 中国性病艾滋病防治1997，3，5： | 12 |
| 8 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 9 | New yellow Ba_(0.93)Eu_(0.07)Al_(2)O_(4) phosphor for warm-white light-emitting diodes through single-emitting-center conversion显示文摘Phosphor-converted white light-emitting diodes for indoor illumination need to be warm-white(i.e.,correlated color temperature,4000 K)with good color rendition(i.e.,color rendering index.80).However,no single-phosphor,single-emitting-center-converted white light-emitting diodes can simultaneously satisfy the color temperature and rendition requirements due to the lack of sufficient red spectral component in the phosphors’emission spectrum.Here,we report a new yellow Ba_(0.93)Eu_(0.07)Al_(2)O_(4) phosphor that has a new orthorhombic lattice structure and exhibits a broad yellow photoluminescence band with sufficient red spectral component.Warm-white emissions with correlated color temperature,4000 K and color rendering index.80 were readily achieved when combining the Ba_(0.93)Eu_(0.07)Al_(2)O_(4) phosphor with a blue light-emitting diode(440–470 nm).This study demonstrates that warm-white light-emitting diodes with high color rendition(i.e.,color rendering index.80)can be achieved based on single-phosphor,single-emitting-center conversion. | Xufan Li John D Budai Feng Liu Jane Y Howe Jiahua Zhang Xiao-Jun Wang Zhanjun Gu Chengjun Sun Richard S Meltzer Zhengwei Pan | 2013 | Light(Science & Applications)2013，2，1： | 11 |
| 10 | Paleoproterozoic basement beneath the southern Jiangxi Province:Evidence from U-Pb ages and Lu-Hf isotopes in zircons from the Doushui lamprophyre显示文摘这篇论文论述侵入的煌斑岩的 geochemical 分析在 Shangyou 县的古苏格兰的 Doushui 花岗石身体,南部的江西省。U-Pb 标明日期和 Hf 同位素分析特别从它为锆石被执行。Petrological 和 geochemical 特征证明煌斑岩属于 high-K,弱碱的辉石黑云母煌斑岩。它被 Mg #(0.74 ) , Ni (253 μg/g ) 和 Cr (893 μg/g ) 满足的高度描绘,并且也在不兼容的元素充实,例如 REE, Rb, Sr, Ba 和 K。它的原语融化,这被建议可能由 non-crust-derived 源于充实的披风 metasomatized 代理人。在煌斑岩标明日期锆石的结果的形态学和 LAM-ICPMS 显示他们是从深外壳的岩石捕获的 xenocrysts。在 ∼1.86 Ga 形成的大多数 xenocrystic 锆石,和在不同 Phanerozoic 时期的一些。Paleoproterozoic 锆石具有 magmatic 起源并且有类似的 176Hf/177 Hf 和 176Lu/177 Hf 比率,显示他们可能从一样的火的地下室岩石。年龄和从这地下室岩石的锆石的 Hf 同位素作文类似于在南部的浙江省的 Paleoproterozoic Danzhu 花岗石的那些,但是极其与 Nanling 地下室区分开来,建议学习区域可能是一向西在东方卡赛西亚·布洛克的 Paleoproterozoic Wuyishan 岩层的延期部分。这些 Paleoproterozoic 锆石有低 Hf 同位素作文,外壳的来源特征。这些锆石的 Hf 模型年龄和在他们以内的更旧的继承核心的存在,结合了可得到的其它数据由以前的研究报导了,建议 Paleoproterozoic 岩浆的来源是 Neoarchaean 外壳,在 Wuyishan 岩层暗示更旧的地下室的存在。U-Pb 年龄和五 Phanerozoic 锆石的 Hf 同位素显示那个 Paleoproterozoic 地下室经历了多重做的发生在古苏格兰, Indosinian 和早 Yanshanian 分别地。古苏格兰的 magmatism 也涉及少年外壳重做。 | YU JinHai WANG LiJuan O'REILLY S Y SHU LiangShu SUN Tao | 2009 | Chinese Science Bulletin2009，54，9： | 10 |
| 11 | Performance of the Prostate Health Index in predicting prostate biopsy outcomes among men with a negative digital rectal examination and transrectal ultrasonography显示文摘[-2]proPSA (p2PSA ) 和它的衍生物, p2PSA-to-free PSA 比率(% p2PSA ) ,和前列腺健康索引(PHI ) 极大地在前列腺活体检视有或没有前列腺癌症(PCa ) 改进了在人之间的辨别。然而,很少在数字直肠的考试(DRE ) 和 transrectal ultrasonography (TRUS ) 是否定的情况中对他们的表演被知道。在有否定 DRE 和 TRUS 的中国的 261 个连续病人的一个未来的队被招募并且经历前列腺活体检视。在活体检视被用来测量各种各样的 PSA 衍生物以前,一件浆液样品收集了,包括总数前列腺特定的抗原(tPSA ) ,免费 PSA,和 p2PSA。为每个病人, free-to-total PSA 比率(% fPSA ) , PSA 密度(PSAD ) , p2PSA-to-free PSA 比率(% p2PSA ) ,和 PHI 是计算的。歧视的性能在在 91% 敏感操作典型曲线(AUC ) 和活体检视率的接收装置下面用区域被估计。在关于年龄, tPSA, % fPSA, PSAD, p2PSA, % p2PSA,和 PHI 的全部队以内的 AUC 分数分别地是 0.598, 0.751, 0.646, 0.789, 0.814, 0.808,和 0.853。PHI 是前列腺活体检视结果的最好的预言者,特别在有 10.1-20 ng ml −1 的 tPSA 的病人。与另外的标记相比,在 91% 的敏感, PHI 为决定哪个人不需要经历活体检视是最有用的,从而避免不必要的过程。PHI 的使用能由在中国与否定 DRE 和 TRUS 在人之中预言前列腺活体检视结果改进 PCa 察觉的精确性。 | Guo-Peng Yu Rong Na Ding-Wei Ye Jun Qi Fang Liu Hai-Tao Chen Yi-Shuo Wu Gui-Ming Zhang Jie-Lin Sun Yao Zhu Li-Qun Huang Shan-Cheng Ren De-Ke Jiang S Lilly Zheng Hao-WenJiang Ying-Hao Sun Qiang Ding Jianfeng Xu | 2016 | Asian Journal of Andrology2016，18，4： | 10 |
| 12 | Necessity and indications of invasive treatment for Budd-Chiari syndrome显示文摘BACKGROUND:The development of collaterals in Budd-Chiari syndrome has been described and these collaterals play an important role in the presentation of this disease.These collaterals are diagnostic and their use in management strategy has never been evaluated.This study aimed to investigate the indications,feasibility and necessity of invasive treatment for patients with Budd-Chiari syndrome and to determine whether such a strategy is necessary for optimal management.METHODS:Twenty-nine patients who had been treated at our unit were enrolled in this study.Based on physical and biochemical examination,and hemodynamic compensation by collaterals,18 patients underwent radiological intervention (group A),while the other 11 had no invasive treatment (group B).The related hemodynamic parameters were acquired when percutaneous angiography was performed.RESULTS:In group A,all patients underwent successfully inferior vena cava (IVC) balloon angioplasty with or without stenting.Four patients also underwent hepatic vein angioplasty.In these patients,the mean IVC pressure before and after treatment was statistically different (29.3±9.2 vs 15.1±4.6 mmHg,P<0.01).The mean IVC pressure was much lower in group B than in group A (12.9±2.4 vs 29.3±9.2 mmHg,P<0.01),but there was no difference from that of the patients after radiological treatment (12.9±2.4 vs 15.1±4.6 mmHg,P>0.05).Median follow-up was 32.3 months (mean 21.3 months;range 3-61 months).In the course of follow-up,the patients in group A survived with good systemic status except for re-stenosis in one patient who underwent re-canalization of the IVC.In group B,10 patients had good systemic status except one patient who had a meso-caval shunt because of deterioration.CONCLUSIONS:The rationale of 'early diagnosis and early treatment' is not suitable for all patients with Budd-Chiari syndrome.Satisfactory survival can be achieved in some patients without invasive treatment,who are completely compensated by rich collaterals.Nonetheless,a positive treatment procedure should be performed if the patient's situation worsens in the course of regular follow-up. | Department of General Surgery (Fu Y,Sun YL,Ma XX,Xu PQ,Feng LS,Tang Z and Luo CH),Institute of Hepatic Vascular Disease (Sun YL),Department of Radiological Intervention (Guan S and Wang ZW),First Affiliated Hospital,Zhengzhou University School of Medicine,Zhengzhou 450052,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 10 |
| 13 | Induction of entosis by epithelial cadherin expression显示文摘房间吞没典型地从后生动物的纸巾为清理指向死了或死的房间。然而,最近的证据证明实时房间能也被指向并且吞没能引起房间死亡。Entosis 是建议调停的一机制吞没并且由他们的邻居,实时肿瘤房间杀死是经常指的一项活动房间同类相食。这里,我们报导在缺乏上皮的 cadherins 的内长的表示的人的胸肿瘤房间的外长的上皮的 cadherin 蛋白质(E-cadherin) 或 P-cadherin ) 的表示导致 entosis 并且禁止转变生长。cadherin 表示导致的 Entosis 在耳中的房间以内与 Rho 和 Rho-kinase (岩石) 活动的极化的分发被联系,它依赖于 p190A RhoGAP 活动。p190A RhoGAP 表示的岩石抑制或 downregulation 减少 entosis 并且增加上皮的表示 cadherin 肿瘤房间的转变生长。这些数据为 entosis 的学习定义新房间系统,并且作为被上皮的粘附的建立导致并且禁止转变生长的房间同类相食的机制识别 entosis。 | Qiang Sun Edmund S Cibas Hongyan Huang Louis Hodgson Michael Overholtzer | 2014 | Cell Research2014，24，11： | 10 |
| 14 | The results and prognosis of different treatment modalities for solitary metastatic lung tumor from nasopharyngeal carcinoma:a retrospective study of 105 cases显示文摘Background and Objective:Nasopharyngeal carcinoma (NPC) is known for its propensity for distant metastases.Lung metastasis is one of the most important causes of death for patients with NPC.Solitary metastatic lung tumor from NPC is a distinctive group associated with a better survival.This study was to find a more effective treatment modality and prognostic factors for the group.Methods:Clinical data of 105 cases of solitary metastatic lung tumor from NPC were retrospectively analyzed.Survival rate was calculated by the Kaplan-Meier method.The difference of survival between the patients treated by different modalities was evaluated by the log-rank test.The Cox univariate and multivariate analyses of gender, age, pathologic type, stage, adjuvant chemotherapy, evaluation of treatment for NPC, disease-free interval, size of metastatic tumor, pulmonary hilar and/or mediastinal lymph node metastasis, treatment modalities, recurrent distant metastases and/or relapse of NPC were conducted.Results:The local control rate was 53.8% in chemotherapy group, 88.0% in radiotherapy +/-chemotherapy group, and 96.4% in operation +/-chemotherapy group (P<0.01).The most promising progression-free survival (PFS) and overall survival (OS) were obtained with operation +/-chemotherapy and followed by radiotherapy +/-chemotherapy.Both of them showed much better efficacy than chemotherapy (P<0.001).The Cox multivariate analysis showed that recurrent distant metastases and/or relapse of NPC affected the survival (OR=2.087, 95% CI=1.277-3.410, P=0.003).The T stage of NPC, size of metastatic tumor, hilar and/or mediastinal lymph node metastasis, and the treatment modality were independent prognostic factors.Conclusions:Operation +/-chemotherapy and radiotherapy +/-chemotherapy are better treatment of solitary metastatic lung tumor from NPC, which could improve the local control and prolong the PFS and OS.Chemotherapy is recommended for patients with higher T stage of NPC, size of metastatic tumor ≥3 cm, pulmonary hilar and/or mediastinal lymph node metastasis. | Jun Ma1,2, Zhe-Sheng Wen1,2, Peng Lin1,2, Xin Wang1,2, Fang-Yun Xie1,3 1 State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P.R.China 2 Department of Thoracic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R.China 3 Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R.China Department of Thoracic Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi 030012, P.R.China | 2010 | Chinese Journal of Cancer2010，29，9： | 9 |
| 15 | Percutaneous transhepatic metal versus plastic biliary stent in treating malignant biliary obstruction: a multiple center investigation显示文摘OBJECTIVE: To compare the efficacy of metal versus plastic biliary stent implantation in the treatmentof malignant biliary obstruction.METHODS: Percutaneous transhepatic self-expandable metal stent (MS, n=61) and 10F plastic stent(PS, n=34) were placed in 95 patients with malignant biliary obstruction in three hospitals of Guangdongprovince. All patients were followed up until death or at least one year after the procedure. Kaplan-Meieranalysis was used to compare the survival of the patients and the rates of stent patency.RESULTS: The 30-day mortality rate was lower in the MS group (6/61, 9.8%) than in the PS group(9/34, 26.5%, P<0.05). The 30-day reobstruction rate and the complication rate were 15.0%, 16.4%in the MS group and 32. 4%, 29. 4% in the PS group, respectively (P<0. 01). The median patencyperiod of stents and median survival period of the patients were 230 days, 224 days in the MS group and90 days, 94 days in the PS group, respectively (P<0. 01).CONCLUSION: Metal stent is clinically superior to plastic stent in the treatment of malignant biliaryobstruction. | Yuan-Xing Guo Yan-Hao Li Yong Chen Ping-Yan Chen Peng-Fei Luo Yong Li Hong Shan Zai-Bo Jiang the Department of Interventional Radiology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China Department of Medical Statistics, First Military Medical University, Guangzhou 510515, China Department of Radiology, Guangdong Provincial People’s Hospital, Guangzhou 510080, China Department of Radiology, Third Affiliated Hospital of Sun Yat-Sen University of Medical Sciences, Guangzhou 510630, China | 2003 | Hepatobiliary & Pancreatic Diseases International2003，2，4： | 8 |
| 16 | Green fluorescent protein (GFP) transgenic pig produced by somatic cell nuclear transfer显示文摘Transgenic somatic cell nuclear transfer is a very promising route for producing transgenic farm ani-mals. Research on GFP transgenic pigs can provide useful information for breeding transgenic pigs, human disease models and human organ xenotransplantation. In this study, a liposomal transfection system was screened and transgenic embryos were reconstructed by nuclear transfer of GFP positive cells into enucleated in vitro matured oocytes. The development of reconstructed embryos both in vitro and in vivo was observed, and GFP expression was determined. The results showed that porcine fe-tal-derived fibroblast cells cultured with 4.0 μL/mL liposome and 1.6 μg/mL plasmid DNA for 6 h re-sulted in the highest transfection rate (3.6%). The percentage of GFP reconstructed embryos that de-veloped in vitro to the blastocyst stage was 10%. Of those the GFP positive percentage was 48%. Re-constructed transgenic embryos were transferred to 10 recipients. 5 of them were pregnant, and 3 de-livered 6 cloned piglets in which 4 piglets were transgenic for the GFP as verified by both GFP protein expression and GFP DNA sequence analysis. The percentage of reconstructed embryos that resulted in cloned piglets was 1.0%; while the percentage of piglets that were transgenic was 0.7%. This is the first group of transgenic cloned pigs born in China, marking a great progress in Chinese transgenic cloned pig research. | LIU ZhongHua SONG Jun WANG ZhenKun TIAN JiangTian KONG QingRan ZHENG Zhong YIN Zhi GAO Li MA HaiKun SUN Shuang LI YuTian WANG HongBin R S PRATHER | 2008 | Chinese Science Bulletin2008，53，7： | 8 |
| 17 | Tensile properties and fracture behavior of Ti_2AlNb based alloys at room temperature显示文摘The tensile mechanical properties and fracture behaviors of Ti 22Al 20Nb 7Ta alloys were studied at room temperature. Three typical microstructures of Ti 2AlNb based alloys were obtained by combination of thermal mechanical processing and heat treat ment. They are: 1) lath mixture of O + B 2 with remaining β grain boundaries and α 2 phase; 2) equiaxed O phase in B 2 matrix; 3) fine lath mixture of O + B 2 without remaining β grain boundaries. It is shown that the microstructure obviously affects the tensile properties of Ti 2AlNb based alloys. The microstructure of fine lath mixture of O + B 2 without remaining β grain boundaries has good combination of yield stress and ductility, while the microstructure with lath mixture of O + B 2 with remaining β grain boundaries and α 2 phase has low yield stress and elongation. The fracture mode was also controlled by the microstructure of Ti 2AlNb based alloys. By means of SEM, it was found that the dominated fracture mode of microstructure with lath mixture of O + B 2 with remained β grain boundary and α 2 phase was intergranular, and the fracture mode of the other two microstructures was mainly transgranular. | PENG Ji hua(彭继华) 1, 2 , MAO Yong(毛 勇) 2, LI Shi qiong(李世琼) 2, SUN Xun fang(孙训方) 2 1. Department of Engineering Mechanics, Southwest Jiaotong University, Chengdu 610031, P.R.China 2. Division of Super Alloys, Central Iron and S | 2000 | 中国有色金属学会会刊:英文版2000，10，3： | 6 |
| 18 | Safety Assesment Model for Fully-Mechanized Coalface | WANG Lian\|guo 1,\ SUN Qiu\|zhi 2,\ WANG Yu\|zhen 3 1. Systems Engineering Institute, Shandong Univercity of Science and Technology Tai′an, 271000 2. Computing Centre, Shandong College of Hydraulic Engineering Tai′an, 271000 3. Institute of S | 2000 | Systems Science and Systems Engineering2000，10，3： | 6 |
| 19 | A novel experience of deferential vessel-sparing microsurgical vasoepididymostomy显示文摘Microsurgical 纵的摄取 vasoepididymostomy (实时) 广泛地被用来对待 epididymal 妨碍的精子缺乏自从 2004。尽管恭敬 vasculature 在供应血到睾丸和 epididymis 起一个重要作用,注意对潜力被给予了的很少在吻合期间 sparing 有益于恭敬容器在实时。这研究试图在人现场评估恭敬容器圆材的功效和安全。从 2013 年 12 月到 2015 年 12 月,有 epididymal 阻塞的 69 个 azoospermic 人在孙中山大学的首先隶属于的医院里现场由于生殖器的感染,损伤,或自发的因素经历了恭敬容器圆材,广州,中国。这些病人的结果回顾地被分析。吝啬的年龄为他们的搭挡是为人和 28.3 年的 31.1 年。59 (85.5% , 59/69 ) 人们被跟随在上面在为约 16 个月的外科以后。明显被精液分析注意并且证实(> 10 000 sperm/ml ) 在 83.1%(49/59 ) 人。自然怀孕率是 40.7%(24/59 ) 在学习底,(21/24 ) 与 87.5% ,这些,自然怀孕在外科以后在 12 以内完成了月。没有严重不利事件或复杂并发症被观察。在这研究,我们在场为 sparing 的一种新奇技术恭敬容器在期间生活。初步的结果显示这种技术与有利明显和怀孕率安全。 | Kun-Long Lyu Jin-Tao Zhuang Philip S Li Yong Gao Liang Zhao Ya-Dong Zhang Ming-Kuan Zhou Jing-Wei Yu Xin Feng Xiang-Zhou Sun Chun-Hua Deng Xiang-An Tu | 2018 | Asian Journal of Andrology2018，20，6： | 6 |
| 20 | Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘 | Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J | 2005 | 第二军医大学学报2005，26，8： | 6 |
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