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| 1 | The Changing Cold Regions Network:Observation,diagnosis and prediction of environmental change in the Saskatchewan and Mackenzie River Basins,Canada显示文摘Climate change is causing rapid and severe changes to many Earth systems and processes,with widespread cryospheric,ecological,and hydrological impacts globally,and especially in high northern latitudes.This is of major societal concern and there is an urgent need for improved understanding and predictive tools for environmental management.The Changing Cold Regions Network(CCRN)is a Canadian research consortium with a focus to integrate existing and new experimental data with modelling and remote sensing products to understand,diagnose,and predict changing land,water,and climate,and their interactions and feedbacks over the geographic domain of the Mackenzie and Saskatchewan River Basins in Canada.The network operates a set of 14 unique and focused Water,Ecosystem,Cryosphere and Climate(WECC)observatories within this region,which provide opportunities to observe and understand processes and their interaction,as well as develop and test numerical simulation models,and provide validation data for remote sensing products.This paper describes this network and its observational,experimental,and modelling programme.An overview of many of the recent Earth system changes observed across the study region is provided,and some local insights from WECC observatories that may partly explain regional patterns and trends are described.Several of the model products being developed are discussed,and linkages with the local to international user community are reviewed—In particular,the use of WECC data towards model and remote sensing product calibration and validation is highlighted.Some future activities and prospects for the network are also presented at the end of the paper. | Chris M DEBEER Howard S WHEATER William L QUINTON Sean K CAREY Ronald E STEWART Murray D MACKAY Philip MARSH | 2015 | Science China Earth Sciences2015，58，1： | 5 |
| 2 | Analysis of a Successful Immune Response against Hepatitis C Virus显示文摘 | Stewart Cooper Ann L Erickson Erin J Adams Joe Kansopon Amy J Weiner David Y Chien Michael Houghton Peter Parham Christopher M Walker | 1999 | Immunity1999，，4： | 3 |
| 3 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 4 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 5 | Predictive value of C D lymphocyte numbers for the development of opportunistic infections and malignancies in HIV-infected persons 显示文摘 | Growes S M Carlin J B Stewart K L | 1991 | J Acquir Immune Defic Sydr1991，4，： | 1 |
| 6 | A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and Laf-1显示文摘 | Hogg N Stewart M P Scarth S L | 1999 | J Clin Invest1999，103，1： | 1 |
| 7 | Mural thrombosis of the heart induced by radiation显示文摘 | BROWN J M FARJARDO L F STEWART J R | 1973 | Arth Pathol1973，96，1： | 1 |
| 8 | Prohibitin an evalutionarily conserved intracellular protein that blocks DNA synthesis in normal fthroblasts and HeLa cells 显示文摘 | Nuell M J Stewart D A Walker L | 1991 | Mal Cell Biol1991，11，3： | 1 |
| 9 | Hashash,Nonlinear Ground-Response Analysis of Turkey Flat Shallow Stiff-soil Site to Strong Ground Motion显示文摘 | Annie 0 L Kwok Jonathan P Stewart Youssef M A | 2008 | Bulletin ot' the Seis- mological Society of America February2008，98，： | 1 |
| 10 | Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice显示文摘 | Stewart M J Plautz G E Del Buono L | 1992 | Hum Gene Ther1992，3，3： | 1 |
| 11 | Differentiation of Hunmn Embryonic Stem Cells into Corneal Epithelia|-like Cells by In Vitro Replication of theComeal Epithelial Stem Cell Niche 显示文摘 | Ahtnad S Stewart R Yung S Kolli S Armstrong L Stojkovie M Figueiredo F IAko M | 2007 | StemCells2007，255，： | 1 |
| 12 | Reduction of chromium (VI) at sub-μg 1-1 levels by fulvic acid 显示文摘 | ECKERT J M STEWART J J WAITE T D SZYMCZAK R WILLIAMS K L | 1990 | Analytica Chimica Acta1990，236，： | 1 |
| 13 | Relating Member Ability and Personality to Work-team Processes and Team Effectiveness显示文摘 | BARRICK M R STEWART G L NEUBERT M J | 1998 | Journal of Applied Psychology1998，83，3： | 1 |
| 14 | Andesite and dacite genesis via contrasting processes: The geology and geochemistry of El Valle Volcano, Panama显示文摘 | DEFANT M J CLARK L F STEWART R H | 1991 | Contrib Mineral Petrol1991，106，： | 1 |
| 15 | Mathematical characterization of maize canopies显示文摘 | Stewart D W Dwyer L M | 1993 | Agric Forest Meteorol1993，66，2： | 1 |
| 16 | Relating member ability and personality to work-team processes and team effectiveness显示文摘 | Barrick M R Stewart G L Neubert M J | 1998 | Journal of Applied Psychology1998，83，3： | 1 |
| 17 | Relating Member Ability and Personality to Work-team Process and Team Effectiveness 显示文摘 | Barrick M R Stewart G L Neubert M J Mount M K | 1998 | Journal of Applied Psychology1998，83，3： | 1 |
| 18 | Ureteroscopic and percutaneous management of upper tract urothelial carcinoma (UTUC): systematic review显示文摘 | CUTRESS M L STEWART G D ZAKIKHANI P | 2012 | BJU Int2012，110，5： | 1 |
| 19 | Temporal variability in terrestrially-derived sources of particulate organic carbon in the lower Mississippi River and its upper tributaries 显示文摘 | Bianchi T S Wysocki L A Stewart M Filley T R McKee B A | 2007 | Geochim Cosmochim Acta2007，71，18： | 1 |
| 20 | Communication Patterns of Primary Care Physicians 显示文摘 | Roter D L Stewart M Putman S M | 1997 | JAMA1997，277，4： | 1 |
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