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| 1 | Premotor biomarkers for Parkinson's disease-a promising direction of research显示文摘The second most serious neurodegenerative disease is Parkinson’s disease(PD).Over the past several decades,a strong body of evidence suggests that PD can begin years before the hallmark clinical motor symptoms appear.Biomarkers for PD are urgently needed to differentiate between neurodegenerative disorders,screen novel therapeutics,and predict eventual clinical PD before the onset of symptoms.Some clinical evaluations and neuroimaging techniques have been developed in the last several years with some success in this area.Moreover,other strategies have been utilized to identify biochemical and genetic markers associated with PD leading to the examination of PD progression and pathogenesis in cerebrospinal fluid,blood,or saliva.Finally,interesting results are surfacing from preliminary studies using known PD-associated genetic mutations to assess potential premotor PD biomarkers.The current review highlights recent advances and underscores areas of potential advancement. | Brian R Haas Tessandra H Stewart Jing Zhang | 2012 | Translational Neurodegeneration2012，1，1： | 5 |
| 2 | HF radio measurements of surface currents显示文摘 | STEWART R H JOY J W | 1974 | Deep Sea Res1974，21，： | 1 |
| 3 | HF radio measurements of surface currents显示文摘 | Stewart R H Joy J W | 1974 | Deep-Sea Res1974，21，12： | 1 |
| 4 | C natural abundance in plant communities along a rainfall gradient: a biological integrator of water availability显示文摘 | Stewart (3 R Turnbull M H Schmidt et ai | 1995 | Australian Journal of Plant Physiology1995，，： | 1 |
| 5 | Management of obstructing lesions of the left colon by resection,on-table lavage and primary anastomosis显示文摘 | Stewart J Diament R H Brennan T G | 1993 | Surgery1993，114，： | 1 |
| 6 | An improved in vivo method for atrioventricu lar node ablation via thoracotomy显示文摘 | Maciver R H Stewart R D Backer C L Tsao S Harrington D A Mavroudis C | 2010 | Braz J Med Biol Res2010，43，： | 1 |
| 7 | Role of unconditioned and conditioned drug effects in the self-administration of opiates andstimulants显示文摘 | Stewart J de Wit H Eikelboom R | 1984 | Psychol Rev1984，91，2： | 1 |
| 8 | Com- parison of intestinal permeabilities determined in mul- tiple in vitro and in situ models:relationship to absorp- tion in humans 显示文摘 | STEWART B H CHAN O H LU R H | 1995 | Pharm Res1995，12，5： | 1 |
| 9 | 13^C natural abundance in plant communities along a rainfall gradient: a biological integrator of water availability显示文摘 | Stewart G R Turnbull M H | 1995 | Funotional Plant Biology1995，22，1： | 1 |
| 10 | Andesite and dacite genesis via contrasting processes: The geology and geochemistry of El Valle Volcano, Panama显示文摘 | DEFANT M J CLARK L F STEWART R H | 1991 | Contrib Mineral Petrol1991，106，： | 1 |
| 11 | Self-reported truck traffic on the street of residence and symptoms of asthma and allergic disease: A glob- al relationship in ISAAC phase 3 显示文摘 | Brunekreef B Stewart A W Anderson H R | 2009 | Environmental Health Perspectives2009，117，11： | 1 |
| 12 | The temporal and spatial analysis of tree age distributions显示文摘 | Duncan R P Stewart G H | 1991 | Canadian Journal of Forest Research1991，21，： | 1 |
| 13 | Overview of randomized trials of postoperativeadjuvant radiotherapy in breast cancer显示文摘 | Cuzick J Stewart H Peto R | 1987 | Cancer Treat Rep1987，71，1： | 1 |
| 14 | The July 27, 1976 Tangshan, China earthquake: A complex sequence of intraplate events显示文摘 | Butler R Stewart G S Kanamori H | 1979 | Bull Seism Soc Smer1979，69，： | 1 |
| 15 | A framework approach for developing parallel adaptive multiphysics applications显示文摘 | STEWART J R EDWARDS H C | 2004 | Finite Elements in Analysis and Design2004，40，： | 1 |
| 16 | Phenotypes of neural- crest-derived cells in vagal and sacral pathways显示文摘 | Anderson R Stewart A L Young H | 2006 | Cell Tissue Res2006，323，： | 1 |
| 17 | Application of local heat induces capillary recruitment in the Pallid bat wing显示文摘 | Widmer R J Stewart R H Young M F | 2007 | Am J Physiol Regul Integr Comp Physiol2007，292，6： | 1 |
| 18 | Comparison of intestinal permeabilities determined in multiple in vitro and in situ models: Relationship to absorption in humans显示文摘 | Stewart B H Chan O H Lu R H | 1995 | Pharm Res1995，12，5： | 1 |
| 19 | Environmental Perceptions and Scanning in the United States and India:Convergence in Entre- preneurial Information Seeking显示文摘 | Stewart W H May R C Kalia A | 2008 | Entrepreneurship Theory and Practice2008，32，1： | 1 |
| 20 | HF radio measurements of surface currents显示文摘 | Stewart R H and J W Joy | 1974 | Deep Sea Res1974，21，： | 1 |
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