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| 1 | Biliary wound healing, ductular reactions, and IL-6/gp130 signaling in the development of liver disease显示文摘在胆汁的树上的 Basic 和翻译创伤愈合研究在皮和胃肠道上在类似的研究后面显著地落后。这是至少对为学习的胆道的容易的存取的缺乏部分可归因。但是临床的关联,对胆汁的上皮的房间(BEC ) 的更多的兴趣 BEC 文化的病理生理学,和普遍可获得性是颠倒这个趋势的因素。在额外肝的胆汁的树上,徒劳的创伤愈合,结疤,苛评开发紧迫发出。在损害的最小的 intra 肝的胆汁管任何一个, BEC 增长或繁的回答能贡献肝疾病。在大、小的胆汁管的慢性炎和坚持的创伤愈合反应经常导致肝癌症。当他们适用于胆道,依赖于表明小径的 IL-6/gp130/STAT3 的细胞的过程的重要性,未答复的问题,和未来方向,愈合的创伤的一般概念被讨论。 | A J Demetris John G Lunz Ⅲ Susan Specht Isao Nozaki | 2006 | World Journal of Gastroenterology2006,12,22: | 15 |
| 2 | Worldwide spread of the Ponseti method for clubfoot显示文摘The Ponseti method has become the gold standard for the treatment of idiopathic clubfoot. Its safety and efficacy has been demonstrated extensively in the literature, leading to increased use around the world over the last two decades. This has been demonstrated by the increase in Ponseti related Pub Med publications from many countries. We found evidence of Ponseti activity in 113 of 193 United Nations members. The contribution of many organizations which provide resources to healthcare practitioners in low and middle income countries, as well as Ponseti champions and modern communication technology, have helped to spread the Ponseti method around the world. Despite this, there are many countries where the Ponseti method is not being used, as well as many large countries in which the extent of activity is unknown. With its low rate of complication, low cost, and high effectiveness,this method has unlimited potential to treat clubfoot in both developed and undeveloped countries. Our listing of countries who have not yet shown presence of Ponseti activity will help non-governmental organizations to target those countries which still need the most help. | Lior Shabtai Stacy C Specht John E Herzenberg | 2014 | World Journal of Orthopedics2014,5,5: | 7 |
| 3 | Molecular Evolution of VEF-Domain-Containing PcG Genes in Plants显示文摘Arabidopsis VERNALIZATION2 (VRN2 ) ,胚胎的 FLOWER2 (EMF2 ) ,和授精无关的 SEED2 (FIS2 ) 分别地涉及调停开花结实促进法的 flowering,植物的发展,和种子开发。和 Arabidopsis VEF-L36,他们分享在植物和动物被保存的一个 VEF 领域。调查 VEF-domain-containing 基因(VEF 基因) 的进化,我们越过陆地植物分析了与 VEF 基因有关的序列。迄今为止,从 11 个被子植物家庭的 24 个全身的序列和从另外一个的 54 个部分序列九个家庭被识别。全身的序列的多数识别了分享最大的顺序类似与并且作为 Arabidopsis EMF2 拥有一样的主要领域结构。象 EMF2 一样序列在被子植物之中是普遍的不仅,但是也在裸子植物, lycophyte,和苔藓的 genomic 序列被发现。没有 FIS2-L36-like 或 VEF-L36-like 序列从除 Arabidopsis 以外的植物被恢复,从整个染色体为被定序的米饭和白杨包括。全身的序列的种系发生的分析在密切相关的 taxa 的 EMF2 相当或相同的事物显示出氨基酸顺序保存的高度。当 clade 在更大的 EMF2 clade 以内嵌套, VRN2 相当或相同的事物被恢复。FIS2 和 VEF-L36 在 VRN2 clade 被恢复。VRN2 clade 可能从在 eurosid 的分叉以前发生在 rosids 的一个 EMF2 复制事件演变我和 eurosid II 系。我们建议在染色体进化的动态变化贡献 VEF-domain-containing 基因的家庭的产生。VEF 领域的种系发生的分析独自显示出序列继续根据种类关系发展后面的 EMF2/VRN2 分叉的那 VEF。在动物并且越过陆地植物的象 EMF2 一样序列的存在建议 EMF2 的一种原型形式在植物和动物系的分叉以前是在场的。A 建议了事件的顺序,基于领域组织和在整个被子植物的中间的序列的出现,能从一个象 EMF2 一样祖先的序列向 VRN2 解释进化,祖先的 EMF2 的可能后面的复制。可得到的数据进一步建议 VEF-L36 和 FIS2 从一个象 VRN2 一样祖先的序列被导出。因此,在一个染色体的 VEF-L36 和 FIS2 的存在可能最终依赖于一个象 VRN2 一样序列的存在。 | Ling-Jing Chen Zhao-Yan Diao Chelsea Specht Z. Renee Sung | 2009 | Molecular Plant2009,2,4: | 6 |
| 4 | 多股射流横向喷入有约束管流过程的模拟(英文)显示文摘用基于控制体的有限差分方法对一排射流横向喷入管流的流场进行了数值分析 ,以建立流场温度分布和上游流动条件及几何参数的关系。可变的参数包括 :喷嘴直径 ,喷嘴数 ,圆柱管半径 ,射流与主流的体积流量比、温度比和动压比。结果发现 ,动压比、喷嘴个数和喷嘴间距是三个重要变量。通过对模拟结果的函数拟合 ,发现射流喷射深度与动压比除以喷嘴数的平方之间的关系可用一个对数函数很好地描述。给出了适于最佳混合的喷射深度和喷嘴间距 。 | 杨涛 Adler W Specht E | 2002 | 推进技术2002,23,2: | 3 |
| 5 | Virus-Induced Gene Silencing in the Culinary Ginger (Zingiber officinale): An Effective Mechanism for Down-Regulating Gene Expression in Tropical Monocots显示文摘导致病毒的基因 silencing (VIGS ) 被显示了有效为短暂在植物到的基因表示击倒在开发和压力相关的回答分析特定的基因的效果。VIGS 很好在 Solanaceae, Brassicaceae, Leguminaceae,和 Poaceae 以内为模型系统和庄稼的研究被建立,但是仅仅最近被用于住在这些家庭外面的植物。这里,我们证明了那个大麦条纹马赛克病毒(BSMV ) 能在 Zingiberaceae 以内感染二种,并且那 BSMVVIGS 能被用于明确地在厨房的生姜姜 officinale 的下面调整 phytoene desaturase。这些结果建议到除谷物以外的 monocots 的 BSMVVIGS 的扩展为许多重要适度、热带的庄稼种类的指导基因分析有潜力。 | Tanya Renner Jennifer Bragg Heather E. Driscoll Juliana Cho Andrew O. Jackson Chelsea D. Specht | 2009 | Molecular Plant2009,2,5: | 2 |
| 6 | Analysis of functions of the chitin deacetylase gene family in Tribolium castaneum显示文摘 | Yasuyuki Arakane Radhika Dixit Khurshida Begum Yoonseong Park Charles A. Specht Hans Merzendorfer Karl J. Kramer Subbaratnam Muthukrishnan Richard W. Beeman | 2009 | Insect Biochemistry and Molecular Biology2009,,5: | 2 |
| 7 | Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects显示文摘 | Radhika Dixit Yasuyuki Arakane Charles A. Specht Chad Richard Karl J. Kramer Richard W. Beeman Subbaratnam Muthukrishnan | 2007 | Insect Biochemistry and Molecular Biology2007,,4: | 2 |
| 8 | Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue 显示文摘 | Specht K Richter T Muller U | 2001 | Am J Pathol2001,158,: | 2 |
| 9 | Probabilistic neural networks显示文摘 | Specht D F | 1990 | J Neural Networks1990,3,1: | 2 |
| 10 | Determination of the ^237Np(n, 2n) ^236 Np cross section at 15 MeV neutron energy显示文摘 | LINDEKE K SPECHT S BORN H J | 1975 | Phys Rev C1975,12,5: | 1 |
| 11 | Temperature tolerance in soybeans显示文摘 | MARTINEAU J R SPECHT J E | 1979 | Crop Science1979,19,: | 1 |
| 12 | Comparison of pretherapeutic and posttherapeutic expression levels of Chemotherapy-Associated genes in adenocarcinomas of the esophagus treated by 5-Fluorouracil - and Cisplatin- Based neoadjuvant chemotherapy 显示文摘 | Langer R Specht K Becker K | 2007 | Am J Clin Pathol2007,28,2: | 1 |
| 13 | Imporving water delivery to the roots of recently transplanted seedling trees:the use of hydrogels to reduce leaf loss and hasten root establishment显示文摘 | Specht A J Harvey-Jones | 2000 | Forest Research2000,1,: | 1 |
| 14 | The application of shellac as an acidic polymer for enteric coating显示文摘 | Felix Specht Marianne Saugestad Tor Waaler | 1999 | Pharmaceutical Technology1999,,3: | 1 |
| 15 | A general regression neural network显示文摘 | Specht D F | 1991 | IEEE Transactions on Neural Networks1991,2,6: | 1 |
| 16 | Probabilistic neural networks for classification, mapping or associate memory显示文摘 | Specht D F | 1988 | Proceedings on the IEEE International Conference on Neural Networks1988,3,1: | 1 |
| 17 | The general regression neural network- rediscovered 显示文摘 | Specht D E | 1993 | Neural Network1993,6,7: | 1 |
| 18 | Pneumatic compression hemodynamies in total hip arthroplasty 显示文摘 | Westrieh G H Specht L M Sharrock N E | 2000 | Clin Orthop2000,372,3: | 1 |
| 19 | Temperature distribution within the moving bed of rotary kilns:Measurement and analysis显示文摘 | LIU Xiao-yan SPECHT E | | 0,,02: | 1 |
| 20 | The general regression neural network-rediscovered显示文摘 | Specht D F | 1993 | Neural Network1993,6,7: | 1 |