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| 1 | A biooptical model of retrieving petroleum concentration in seawater显示文摘A biooptical modeling, which is based on a radiation transfer model, can be employed to simultaneously retrieve the concentration of various colour factors by multi-spectral remote sensing data, after connecting inherent optical properties(absorption coefficient and backward scattering coefficient) of colour factor with apparent optical properties(remote sensing reflectivity). At present, this method has been used in a relatively wide range of applications in the inversion of a conventional water colour factor concentration in the case II water body: applications such as chlorophyll, suspended sediment, yellow substance. On the basis of extensive field testing data of water quality, correspondingly apparent optical properties, and the full use of the existing parametric model of colour factor inherent optical properties(with the parametrization of petroleum substance inherent optical properties established in the project) the remote recognition model for oil concentration is established by introducing oil as a new water colour factor into a biooptical remote algorithm. The estimated value of the oil concentration was obtained by solving the biooptical model, using the data measured in May 2008 and August 2009 and June 2010 in seawater. The highly accurate inversion result promises to estimate the oil concentration in water for remote sensing. | HUANG Miaofen SONG Qingjun XING Xufeng ZHAO Zulong | 2014 | Acta Oceanologica Sinica2014，33，5： | 8 |
| 2 | A new algorithm of retrieving a petroleum substances absorption coefficient in sea water based on a remote sensing image显示文摘Establishing the remote sensing algorithm of retrieving the absorption coefficient of seawater petroleum substances is an efficient way to improve the accuracy of retrieving a seawater petroleum concentration using a remote sensing technology. A remote sensing reflectance is a basic physical parameter in water color remote sensing. Apply it to directly retrieve the absorption coefficient of seawater petroleum substances is of potential advantage. The absorption coefficient of waters containing petroleum [ACWCP, a_o(λ)], consists of the absorption coefficient of pure water [ACPW, a_w(λ)], plankton [ACP, a_(ph)(λ)], colored scraps [ACCS, a_(d,g)(λ)], and petroleum substance [ACPS, a_(oil)(λ)]. Among those, ACCS consists of the absorption coefficient of nonalgal particle [ACNP, a_d(λ)] and colored dissolved organic matter [ACCDOM, a_g(λ)]. For waters containing petroleum, the retrieved ACCS using the existing method is a combination absorption coefficient of ACNP,ACCDOM and ACPA [CAC, a_(d,g,oil)(λ)]. Therefore, the principle question is how to extract ACPS from CAC.Through the analysis of the three proportion tests conducted between the year of 2013 and 2015 and the corresponding remote sensing data, an algorithm of retrieving the absorption coefficient of petroleum substances is proposed based on remote sensing reflectance. First of all, ACPS and CAC are retrieved from the reflectance using the quasi-analytical algorithm(QAA), with some parameter modified. Secondly, given the fact that the backscatter coefficient [BC, b_(bp)(555)] of total particles at 555 nm can be obtained completely from the reflectance, the relation between BC and ACNP in petroleum contaminated water can be established. As a result, ACNP can be calculated. Then, combining the remote sensing retrieving algorithm of a_g(440), the method of achieving the spectral slope of the absorption coefficient can be established, from which ACCDOM,can be calculated. Finally, ACPS can be computed as the residual. The accuracy of ACPS based on this algorithm is 86% compared with the in situ measurements. | HUANG Miaofen XING Xufeng SONG Qingjun LIU Yang DONG Wentong | 2016 | Acta Oceanologica Sinica2016，35，11： | 7 |
| 3 | Hepatitis C Virus Infection Downregulates the Ligands of the Activating Receptor NKG2D显示文摘Natural killer (NK) cells are a major component of the host innate immune defense against various pathogens. Several viruses, including hepatitis C virus (HCV), have developed strategies to evade the NK-cell response. In our study, we found HCV infection could trigger DNA damage response by both ataxia telangiectasia mutated (ATM) and ATM- and Rad3-related (ATR) pathways. Recent reports had revealed that NKG2D ligands (NK cell-activating ligands) were upregulated when a major DNA damage checkpoint pathway was activated. However, here we found that DNA damage response was activated but NKG2D ligands were downregulated upon HCV infection. Further studies showed that the protease NS3/4A of HCV which had been shown relation with immune invasion contributed to the reduced expression of NKG2D ligands. These findings provide a novel insight into the mechanisms evolved by HCV to escape from the NK cell response. | Chaoyang Wen Xiang He Hongfang Ma Ningbo Hou Congwen Wei Ting Song Yanhong Zhang Liping Sun Qingjun Ma Hui Zhong | 2008 | Cellular & Molecular Immunology2008，5，6： | 6 |
| 4 | FY-3A/MERSI, ocean color algorithm, products and demonstrative applications显示文摘A medium resolution spectral imager (MERSI) on-board the first spacecraft of the second generation of China's polar-orbit meteorological satellites FY-3A, is a MODIS-like sensor with 20 bands covering visible to thermal infrared spectral region. FY-3A/MERSI is capable of making continuous global observations, and ocean color application is one of its main targets. The objective is to provide information about the ocean color products of FY-3A/MERSI, including sensor calibration, ocean color algorithms, ocean color products validation and applications. Although there is a visible on-board calibration device, it cannot realize the on-board absolute radiometric calibration in the reflective solar bands. A multisite vicarious calibration method is developed, and used for monitoring the in-flight response change and providing post-launch calibration coefficients updating. FY-3A/MERSI ocean color products consist of the water-leaving reflectance retrieved from an atmospheric correction algorithm, a chlorophyll a concentration (CHL1) and a pigment concentration (PIG1) from global empirical models, the chlorophyll a concentration (CHL2), a total suspended mater concentration (TSM) and the absorption coefficient of CDOM and NAP (YS443) from China's regional empirical models. The atmospheric correction algorithm based on lookup tables and ocean color components concentration estimation models are described. By comparison with in situ data, the FY-3A/MERSI ocean color products have been validated and preliminary results are presented. Some successful ocean color applications such as algae bloom monitoring and coastal suspended sediment variation have demonstrated the usefulness of FY-3A/MERSI ocean color products. | SUN Ling GUO Maohua ZHU Jianhua HU Xiuqing SONG Qingjun | 2013 | Acta Oceanologica Sinica2013，32，5： | 4 |
| 5 | Proliferating cell nuclear antigen destabilizes c-Abl tyrosine kinase and regulates cell apoptosis in response to DNA damage显示文摘 | Xiang He Congwen Wei Ting Song Jing Yuan Yanhong Zhang Qingjun Ma Wei Shi Hui Zhong | 2009 | Apoptosis2009，，3： | 1 |
| 6 | Comparative study of tribological properties of insulated and conductive polyimide composites显示文摘Insulated polyimide(PI)composites filled with short glass fibers(SGF),polytetrafluoroethylene(PTFE),SiO2,and polyphenylene(PPL)are specially designed,prepared,and the tribological properties are systematically investigated with references to the special requirements for frictional materials used in ultrasonic motors.The hardness and thermal decomposition temperature of the insulated PI composites are comparable to that of conductive PI composites.However,these insulated materials present excellent friction and wear performance,especially under high loads and speeds.Scanning electron microscopy(SEM)analysis of the worn surface indicates that adhesive and fatigue wear dominate the wear mechanisms. | Jingfu SONG Yuanhao YU Gai ZHAO Jinhao QIU Qingjun DING | 2020 | Friction2020，8，3： | 1 |
| 7 | Simvastatin induces osteoblastic differentiation and inhibits adipocytic differentiation in mouse bone marrow stromal cells显示文摘 | Chunli Song Zhaoqing Guo Qingjun Ma Zhongqiang Chen Zhongjun Liu Hongti Jia Gengting Dang | 2003 | Biochemical and Biophysical Research Communications2003，，3： | 1 |
| 8 | Overexpression of Bmi-1 contributes to the invasion and metastasis ofhepatocellular carcinoma by increasing the expression of matrix metalloproteinase(MMP)?2, MMP-9 and vascular endothelial growth factor via the PTEN/PI3K/Akt pathway显示文摘 | Xiaolei Li Zhaoxu Yang Wenjie Song Liang Zhou Qingjun Li Kaishan Tao Jingshi Zhou Xing Wang Zhigang Zheng Nan You Kefeng Dou Haimin Li | 2013 | International Journal of Oncology2013，，3： | 1 |
| 9 | Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation显示文摘Excessive inflammatory responses contribute to the pathogenesis and lethality of highly pathogenic human coronaviruses,but the underlying mechanism remains unclear.In this study,the N proteins of highly pathogenic human coronaviruses,including severe acute respiratory syndrome coronavirus(SARS-CoV),middle east respiratory syndrome coronavirus(MERS-CoV)and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),were found to bind MASP-2,a key serine protease in the lectin pathway of complement activation,resulting in excessive complement activation by potentiating MBL-dependent MASP-2 activation,and the deposition of MASP-2,C4b,activated C3 and C5b-9.Aggravated inflammatory lung injury was observed in mice infected with adenovirus expressing the N protein.Complement hyperactivation was also observed in SARS-CoV-2-infected patients.Either blocking the N protein:MASP-2 interaction,MASP-2 depletion or suppressing complement activation can significantly alleviate N protein-induced complement hyperactivation and lung injury in vitro and in vivo.Altogether,these data suggested that complement suppression may represent a novel therapeutic approach for pneumonia induced by these highly pathogenic coronaviruses. | Ting Gao Lin Zhu Hainan Liu Xiaopeng Zhang Tingting Wang Yangbo Fu Hongzhen Li Qincai Dong Yong Hu Zhang Zhang Jing Jin Zijing Liu Weihong Yang Yaoning Liu Yanwen Jin Kaitong Li Yongjiu Xiao Junli Liu Huailong Zhao Yue Liu Ping Li Jibo Song Lu Zhang Yuwei Gao Sisi Kang Shoudeng Chen Qingjun Ma Xiuwu Bian Wei Chen Xuan Liu Qing Mao Cheng Cao | 2022 | Signal Transduction and Targeted Therapy2022，7，10： | 0 |
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