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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 3 | Leadership and excellence in schooling显示文摘 | Sergio vanni T | 1984 | Educational Leadership1984，41，05： | 1 |
| 4 | Subclass problem-dependent design for error-correcting output codes 显示文摘 | SERGIO E DAVID M J T ORIOL P | 2008 | IEEE Transactions on Pattern Analysis and Machine Intelligence2008，30，6： | 1 |
| 5 | Synthesis of a novel ditopic ligand incorporating directly bonded 1,10-phenanthroline and 2,2 2:6 2″-terpyridine units显示文摘 | SERGIO T | 2006 | Tetrahedron Letters2006，47，： | 1 |
| 6 | In vitro studies of the effects of aflatoxin B~ and fumonisin B1 on trypsin -like and collagenase -like activity from the hepatopan- creas of white shrimp (Litopenaeus vannamei) 显示文摘 | Armando B Sergio I F Wilfrido T | 2005 | Aq- uaculture2005，250，： | 1 |
| 7 | Simulation in the Supply Chain Context: a Survey 显示文摘 | T Sergio C Sergio | 2004 | Computers in Industry (SO 166-3615)2004，53，2： | 1 |
| 8 | Mitochondrial DNA mutation at the D310(displacement loop)mononucleotide sequence in the pathogenesis of gallbladder carcinoma显示文摘 | MOYING T SERGIO B MARTHA P | 2004 | Clin Cancer Res2004，10，3： | 1 |
| 9 | Phenotyping vigour control capacity of new peach rootstocks by xylem vessel analysis 显示文摘 | SERGIO T ALI A THEODORE M D | 2011 | Scientia Horticulturae2011，127，3： | 1 |
| 10 | Low-resistivity Zn O∶F∶Al Transparent Thin Films显示文摘 | Delia C A Gerardo T D Sergio J S | 2004 | Solar Energy Material&Solar Cells2004，82，1： | 1 |
| 11 | Control system design on a power-split CVT for high-power agricultural tractors显示文摘 | Sergio M S Francesco L T | 2004 | IEEE/ASME Transactions on Mechatronics2004，9，3： | 1 |
| 12 | Blockage ofdopaminergic D2 receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation显示文摘 | Marcelo MSL Angela BR Andressa S Monica LA Adriano Z Sílvio MZ Maria ABFV Sergio T | | 0，，： | 1 |
| 13 | Transesterification of soybean oil catalyzed by sulfated zirconia 显示文摘 | CAMILA M G SERGIO T LETICIA L M | 2008 | Bioresour Technol2008，99，： | 1 |
| 14 | Sleep rebound in animals deprived of paradoxical sleep by the modified multiple platform method 显示文摘 | Deborah S Beatyiz DP Sergio T | 2000 | Brain Research2000，875，12： | 1 |
| 15 | Simulation in the supply chain context: a survey显示文摘 | SERGIO T SERGIO C | 2004 | Computers in Industry2004，53，1： | 1 |
| 16 | Synthesis of a novel ditopic ligand incorporating directlybonded 1,10-phenanthroline and 2,20:60,200-terpyridine units显示文摘 | SERGIO T | 2006 | Tetrahedron Letters2006，47，： | 1 |
| 17 | Head, eye and arm coordination in table tennis 显示文摘 | SERGIO T R JOAN N V WILLIAMS M A | 2002 | Journal of Sports Sciences2002，，20： | 1 |
| 18 | Reliable low-density DNA array based on allele-specific probes for detection of 118 mutations causing familial hypercholesterolemia 显示文摘 | Diego T Sergio C Pilaf M | 2005 | Clin Chem2005，51，7： | 1 |
| 19 | Simulation in the supply chain context: a survey显示文摘 | SERGIO T SERGIO C | 2004 | Computers in Industry2004，53，1： | 1 |
| 20 | Introduction To Image Stabilization显示文摘 | Scott W T Sergio R | 2006 | Tutorial Text in Optical Engineering SPIE2006，73，： | 1 |
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