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8篇 您的检索式：作者名="Ryusuke Ito"

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		题名	作者	年代	出处	被引量
	1	Hepatic reconstruction from fetal porcine liver cells using a radial flow bioreactor显示文摘AIM: To examine the efficacy of the radial flow bioreactor (RFB) as an extracorporeal bioartificial liver (BAL) and the reconstruction of liver organoids using embryonic pig liver cells. METHODS: We reconstructed the liver organoids using embryonic porcine liver cells in the RFB. We also determined the gestational time window for the optimum growth of embryonic porcine liver cells. Five weeks of gestation was designated as embryonic day (E) 35 and 8 wk of gestation was designated as E56. These cells were cultured for one week before morphological and functional examinations. Moreover, the efficacy of pulsed administration of a high concentration hepatocyte growth factor (HGF) was examined. RESULTS: Both cell growth and function were excellent after harvesting on E35. The pulsed administration of a high concentration of HGF promoted the differentiation and maturation of these fetal hepatic cells. Microscopic examination of organoids in the RFB revealed palisading and showed that bile duct-like structures were well developed, indicating that the organoids were mini livers. Transmission electron microscopy revealed microvilli on the luminal surfaces of bile duct-like structures and junctional complexes, which form the basis of the cytoskeleton of epithelial tissues. Furthermore, strong expression of connexin (Cx) 32, which is the main protein of hepatocyte gap junctions, was observed. With respect to liver function, ammonia detoxification and urea synthesis were shown to be performed effectively. CONCLUSION: Our system can potentially be applied in the fields of BAL and transplantation medicine.	Yuji Ishii Ryota Saito Hideki Marushima Ryusuke Ito Taro Sakamoto Katsuhiko Yanaga	2008	World Journal of Gastroenterology2008，14，17：	3
	2	Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice显示文摘	Reiko Ito Masakazu Kita Masaharu Shin-Ya Tsunao Kishida Atsuyo Urano Ryusuke Takada Junichi Sakagami Jiro Imanishi Yoichiro Iwakura Takeshi Okanoue Toshikazu Yoshikawa Keisho Kataoka Osam Mazda	2008	Biochemical and Biophysical Research Communications2008，，1：	1
	3	Negative Impact of Blood Transfusion on Recurrence and Prognosis of Hepatocellular Carcinoma After Hepatic Resection显示文摘	Hiroaki Shiba Yuichi Ishida Shigeki Wakiyama Tomonori Iida Michinori Matsumoto Taro Sakamoto Ryusuke Ito Takeshi Gocho Kenei Furukawa Yuki Fujiwara Shoichi Hirohara Takeyuki Misawa Katsuhiko Yanaga	2009	Journal of Gastrointestinal Surgery2009，，9：	1
	4	Negative Impact of Blood Transfusion on Recurrence and Prognosis of Hepatocellular Carcinoma After Hepatic Resection显示文摘	Hiroaki Shiba Yuichi Ishida Shigeki Wakiyama Tomonori Iida Michinori Matsumoto Taro Sakamoto Ryusuke Ito Takeshi Gocho Kenei Furukawa Yuki Fujiwara Shoichi Hirohara Takeyuki Misawa Katsuhiko Yanaga	2009	Journal of Gastrointestinal Surgery2009，，9：	1
	5	Single‐incision laparoscopic surgery for giant hepatic cyst显示文摘	Takeshi Gocho Takeyuki Misawa Fumitake Suzuki Ryusuke Ito Hiroaki Shiba Yasuro Futagawa Shigeki Wakiyama Yuichi Ishida Katsuhiko Yanaga	2013	Asian J Endosc Surg2013，，3：	1
	6	Prognostic significance of receptor for advanced glycation end products expression in hepatocellular carcinoma after hepatectomy显示文摘	Ryusuke Ito Yuji Ishii Shigeki Wakiyama Hiroaki Shiba Shuichi Fujioka Takeyuki Misawa Yuichi Ishida Hiroshi Hano Katsuhiko Yanaga	2014	Journal of Surgical Research2014，，：	1
	7	Single‐incision laparoscopic distal pancreatectomy with or without splenic preservation: How we do it显示文摘	Takeyuki Misawa Ryusuke Ito Yasuro Futagawa Yuki Fujiwara Hiroaki Kitamura Nobuhiro Tsutsui Hiroaki Shiba Shigeki Wakiyama Yuichi Ishida Katsuhiko Yanaga	2012	Asian J Endosc Surg2012，，4：	1
	8	Negative Impact of Blood Transfusion on Recurrence and Prognosis of Hepatocellular Carcinoma After Hepatic Resection显示文摘	Hiroaki Shiba Yuichi Ishida Shigeki Wakiyama Tomonori Iida Michinori Matsumoto Taro Sakamoto Ryusuke Ito Takeshi Gocho Kenei Furukawa Yuki Fujiwara Shoichi Hirohara Takeyuki Misawa Katsuhiko Yanaga	2009	Journal of Gastrointestinal Surgery2009，，9：	1

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