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| 1 | Gastric cancer arising from the remnant stomach after distal gastrectomy:A review显示文摘Gastric stump carcinoma was initially reported by Balfore in 1922,and many reports of this disease have since been published. We herein review previous reports of gastric stump carcinoma with respect to epidemiology,carcinogenesis,Helicobacter pylori(H. pylori) infection,Epstein-Barr virus infection,clinicopathologic characteristics and endoscopic treatment. In particular,it is noteworthy that no prognostic differences are observed between gastric stump carcinoma and primary upper third gastric cancer. In addition,endoscopic submucosal dissection has recently been used to treat gastric stump carcinoma in the early stage. In contrast,many issues concerning gastric stump carcinoma remain to be clarified,including molecular biological characteristics and the carcinogenesis of H.pylori infection.We herein review the previous pertinent literature and summarize the characteristics of gastric stump carcinoma reported to date. | Shinsuke Takeno Tatsuya Hashimoto Kenji Maki Ryosuke Shibata Hironari Shiwaku Ippei Yamana Risako Yamashita Yuichi Yamashita | 2014 | World Journal of Gastroenterology2014，20，38： | 13 |
| 2 | Development and application of traffic accident density estimation models using kernel density estimation显示文摘Traffic accident frequency has been decreasing in Japan in recent years.Nevertheless,many accidents still occur on residential roads.Area-wide traffic calming measures including Zone 30,which discourages traffic by setting a speed limit of 30 km/h in residential areas,have been implemented.However,no objective implementation method has been established.Development of a model for traffic accident density estimation explained by GIS data can enable the determination of dangerous areas objectively and easily,indicating where area-wide traffic calming can be implemented preferentially.This study examined the relations between traffic accidents and city characteristics,such as population,road factors,and spatial factors.A model was developed to estimate traffic accident density.Kernel density estimation(KDE) techniques were used to assess the relations efficiently.Besides,16 models were developed by combining accident locations,accident types,and data types.By using them,the applicability of traffic accident density estimation models was examined.Results obtained using Spearman rank correlation show high coefficients between the predicted number and the actual number.The model can indicate the relative accident risk in cities.Results of this study can be used for objective determination of areas where area-wide traffic calming can be implemented preferentially,even if sufficient traffic accident data are not available. | Seiji Hashimoto Syuji Yoshiki Ryoko Saeki Yasuhiro Mimura Ryosuke Ando Shutaro Nanba | 2016 | Journal of Traffic and Transportation Engineering(English Edition)2016，3，3： | 3 |
| 3 | Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosisin response to heat stress or mechanical stress显示文摘 | Ken Takebe Takayuki Nishiyama Shinya Hayashi Shingo Hashimoto Takaaki Fujishiro Noriyuki Kanzaki Kohei Kawakita Kenjiro Iwasa Ryosuke Kuroda Masahiro Kurosaka | 2011 | International Journal of Molecular Medicine2011，，： | 1 |
| 4 | Analytical study on uneven heating relaxation of food inside industrial microwave oven by means of water film显示文摘 | RYOSUKE SUGA TAICHI IJUIN OSAMU HASHIMOTO | 2007 | Microwave and Optical Technology Letters2007，49，3： | 1 |
| 5 | Lactic acid bacteria display on the cell surface cytosolic proteins that recognize yeast mannan 显示文摘 | Yoshio Katakura Ryosuke Sano Takashi Hashimoto | 2010 | Applied Microbiology and Biotechnology2010，86，1： | 1 |
| 6 | Increased Circulating Hepatocyte Growth Factor in the Early Stage of Acute Myocardial Infarction显示文摘 | Akira Matsumori Yutaka Furukawa Tetsuo Hashimoto Koh Ono Tetsuo Shioi Masaharu Okada Atsushi Iwasaki Ryosuke Nishio Shigetake Sasayama | 1996 | Biochemical and Biophysical Research Communications1996，，2： | 1 |
| 7 | Lactic acid bacteria display on the cell surface cytosolic proteins that recognize yeast mannan 显示文摘 | ~oshio Katakura Ryosuke Sano Takashi Hashimoto | 2010 | Applied Microbiology and Biotechnology2010，86，1： | 1 |
| 8 | Conversion hepatectomy for hepatocellular carcinoma with main portal vein tumour thrombus after lenvatinib treatment: A case report显示文摘BACKGROUND Hepatocellular carcinoma(HCC)accompanied by portal vein tumour thrombus(PVTT)presents an aggressive disease course,worsening liver function reserve,and a high recurrence rate.Clinical practice guidelines recommend systemic therapy as the first-line option for HCC with portal invasion.However,to achieve longer survival in these patients,the treatment strategy should be concluded with removal of the tumour by locoregional therapy.We experienced a case of initially unresectable HCC with main PVTT converted to radical hepatectomy after lenvatinib treatment.CASE SUMMARY A 59-year-old male with chronic hepatitis C infection visited our clinic as a regular post-surgery follow-up.Contrast-enhanced abdominal computed tomography revealed a liver mass diffusely located at the lateral segment with a massive PVTT extending from the umbilical portion to the main and contralateral third-order portal branches.With the diagnosis of unresectable HCC with Vp4(main trunk/contralateral branch)PVTT,lenvatinib was started at 12 mg/d.The computed tomography taken 3 mo after starting lenvatinib showed regression of the PVTT,which had retreated to the contralateral first-order portal branch.He tolerated the full dose without major adverse effects.With cessation of lenvatinib for 7 d,radical left lobectomy and PVTT thrombectomy were conducted.The patient’s postoperative course was uneventful.Microscopically,the primary lesion showed fibrotic changes,with moderately to poorly differentiated tumour cells surrounded by granulation tissues in some areas.The majority of the PVTT showed necrosis.He was alive without recurrence for 8 mo.CONCLUSION This is the first case of HCC with Vp4 PVTT in which radical conversion hepatectomy was succeeded after lenvatinib treatment. | Kazuhiro Takahashi Jaejeong Kim Amane Takahashi Shinji Hashimoto Manami Doi Kinji Furuya Ryosuke Hashimoto Yohei Owada Koichi Ogawa Yusuke Ohara Yoshimasa Akashi Katsuji Hisakura Tsuyoshi Enomoto Osamu Shimomura Masayuki Noguchi Tatsuya Oda | 2021 | World Journal of Hepatology2021，13，3： | 1 |
| 9 | Experimental confirmation of physical metal penetration generation and press casting production considering molten metal's pressure control显示文摘This paper presents a technique for controlling the pressure of a molten metal when using a new type of iron casting method called sand mold press casting to realize high productivity and obtain high-quality products.The past test results using this method showed a casting yield of 90% to 95%,while conventional methods only show a casting yield of 60% to 70%.Although the press casting method does not require a sprue cup or runner channel casting defects such as metal penetration are often caused by the high pressure in the high-velocity pressing part of this casting process.Therefore,we proposed a pressure control method with a mathematical model of molten metal pressure,and with it we achieved experimental confirmation of the successful production of brake drums at different pressing temperatures.Results show that the proposed pressing control method can realize sound,penetration-free casting production.However,the theoretical analysis and design of this pressing process had not previously been studied sufficiently,and therefore this paper presents the theoretical design algorithm for the process as well as its experimental confirmation. | Ryosuke Tasaki Yoshiyuki Noda Kunihiro Hashimoto Kazuhiko Terashima | 2012 | China Foundry2012，9，1： | 0 |
| 10 | Temporal Changes in Transboundary Air Pollutants in Bottom Sediments of Lakes in East Asia显示文摘 | Shlntaro Mura Ryosuke Sato Masaki Hashimoto Akiko Murakami-Kitase Hideo Yamazaki Shusaku Yoshikawa Ju-Yong Kim Kazuo Kamura | 2013 | Journal of Environmental Science and Engineering(B)2013，2，11： | 0 |
| 11 | 大鼠静脉持续输注瑞芬太尼可诱发输注时长相关性一过性痛觉过敏显示文摘背景最近研究表明,瑞芬太尼和其他仙型阿片受体激动剂一样可能会引起痛觉过敏。因此,我们拟通过动物实验(采用临床实践中应用的管理模型)研究静脉给予瑞芬太尼,观察瑞芬太尼是否可以日l起痛觉过敏以其Bj起痛觉过敏的条件。此外,我们还研究输注瑞芬太尼引起的痛觉过敏是否与细胞外信号调节蛋白ERK1/2激酶磷酸化有关。方法雄性SD大鼠,经尾静脉置管,持续给予瑞芬太尼(30μg·kg^-1·min^-1)10分钟,或持续给予瑞芬太尼(0.1/1/10μg·kg^-1·min^-1)30分钟,或给予瑞芬太尼(0.1/1/3/10μg·kg^-1·min^-1)120分钟。随后行vonFrey测试及甩尾实验,并用免疫组化法测ERK1/2蛋白表达。在此基础上,观察鞘内预先给予MAPK抑制剂U0126是否可抑制瑞芬太尼引起痛觉过敏。结果瑞芬太尼的镇痛作用呈剂量依赖性,作用时间短恢复迅速。10分钟或30分钟的输注不会引起痛觉过敏。然而,各种剂量的瑞芬太尼120分钟组与对照组相比,甩尾潜伏期和终止输液后机械痛阈值均降低。但痛觉过敏持续时间不超过60分钟。与瑞芬太尼30分钟组(无痛觉过敏)相比,瑞芬太尼120分钟组(有痛觉过敏)脊髓背侧角神经元ERK1/2磷酸化明显增加,但U0126并不能抑制输注瑞芬太尼所导致的痛觉过敏。结论静脉输注瑞芬太尼可以引起短暂的药物撤退性痛觉过敏。这种痛觉过敏与瑞芬太尼持续输注的时间有关。与我们的假设相反,ERK1/2并不是51起痛觉过敏的一个必要因素。 | Ryosuke Ishida Tetsuro Nikai Tatsuya Hashimoto Toshiko Tsumori Yoji Saito 李卉(译) 王焱林(校) | 2013 | 麻醉与镇痛2013，，2： | 0 |
| 12 | Modelling and Control of Pressurized Molten Metal in Press Casting显示文摘 | Ryosuke Tasaki Yoshiyuki Noda Kunihiro Hashimoto Kazuhlro Terashlma | 2012 | Journal of Mechanics Engineering and Automation2012，2，2： | 0 |
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