|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 跨境电商实践教学存在的问题及未来发展趋势显示文摘实践教学作为跨境电商人才培养的重要组成部分,对创新型、复合型、应用型、国际型人才的培养发挥着重要的作用。对跨境电商实践教学存在的现状进行分析,指出当前跨境电商实践教学存在实战不可行、模拟有局限和实践需深化三个方面的问题。同时,结合对跨境电商行业的理解,指出跨境电商实践教学分为以平台模拟为主要特征的1.0阶段、以综合训练为主要特征的2.0阶段、以数据化运营为主要特征的3.0阶段以及以数据化的全面融入为主要特征的4.0阶段。当前跨境电商实践教学总体上处于3.0阶段,并提出在可预见的跨境电商实践教学4.0阶段,数据将和课程全面融合,跨境电商知识体系将被重构,并对院校人才培养产生深远影响。 | 邹益民 Gerasimov Ruslan Zhang Xiaocan | 2021 | 对外经贸2021，，2： | 10 |
| 2 | Acute right lower abdominal pain in women of reproductive age:Clinical clues显示文摘AIM:To study possible gynecological organ pathologies in the differential diagnosis of acute right lower abdominal pain in patients of reproductive age.METHODS:Following Clinical Trials Ethical Committee approval,the retrospective data consisting of physical examination and laboratory findings in 290 patients with sudden onset right lower abdominal pain who used the emergency surgery service between April2009 and September 2013,and underwent surgery and general anesthesia with a diagnosis of acute appendicitis were collated.RESULTS:Total data on 290 patients were obtained.Two hundred and twenty-four(77.2%)patients had acute appendicitis,whereas 29(10%)had perforated appendicitis and 37(12.8%)had gynecological organ pathologies.Of the latter,21(7.2%)had ovarian cyst rupture,12(4.2%)had corpus hemorrhagicum cyst rupture and 4(1.4%)had adnexal torsion.Defense,Rovsing’s sign,increased body temperature and increased leukocyte count were found to be statistically significant in the differential diagnosis of acute appendicitis and gynecological organ pathologies.CONCLUSION:Gynecological pathologies in women of reproductive age are misleading in the diagnosis of acute appendicitis. | Sinan Hatipoglu Filiz Hatipoglu Ruslan Abdullayev | 2014 | World Journal of Gastroenterology2014，20，14： | 8 |
| 3 | Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury显示文摘The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited,especially in case of severe injury.This often leads to poor motor function and permanent disability.Existing approaches for the treatment of injured nerves do not provide appropriate conditions to support survival and growth of nerve cells.This drawback can be compensated by the use of gene therapy and cell therapy-based drugs that locally provide an increase in the key regulators of nerve growth,including neurotrophic factors and extracellular matrix proteins.Each growth factor plays its own specific angiotrophic or neurotrophic role.Currently,growth factors are widely studied as accelerators of nerve regeneration.Particularly noteworthy is synergy between various growth factors,that is essential for both angiogenesis and neurogenesis.Fibroblast growth factor 2 and vascular endothelial growth factor are widely known for their proangiogenic effects.At the same time,fibroblast growth factor 2 and vascular endothelial growth factor stimulate neural cell growth and play an important role in neurodegenerative diseases of the peripheral nervous system.Taken together,their neurotrophic and angiogenic properties have positive effect on the regeneration process.In this review we provide an in-depth overview of the role of fibroblast growth factor 2 and vascular endothelial growth factor in the regeneration of peripheral nerves,thus demonstrating their neurotherapeutic efficacy in improving neuron survival in the peripheral nervous system. | Kamilla Faritovna Idrisova Alina Kazymovna Zeinalova Galina Andreevna Masgutova Alexey Andreevich Bogov Jr. Cinzia Allegrucci Valeriia Yurievna Syromiatnikova Ilnur Ildusovich Salafutdinov Ekaterna Evgenievna Garanina Dina Ivanovna Andreeva Adilet Abdullaatovich Kadyrov Albert Anatolevich Rizvanov Ruslan Faridovich Masgutov | 2022 | Neural Regeneration Research2022，17，6： | 6 |
| 4 | Effect of laparoscopic abdominal surgery on splanchnic circulation: Historical developments显示文摘With the developments in medical technology and increased surgical experience,advanced laparoscopic surgical procedures are performed successfully.Laproscopic abdominal surgery is one of the best examples of advanced laparoscopic surgery(LS).Today,laparoscopic abdominal surgery in general surgery clinics is the basis of all abdominal surgical interventions.Laparo scopica bdomina l surgery is associated with systemic and splanchnic hemodynamic alterations.Inadequate splanchnic perfusion in critically ill patients is associated with increased morbidity and mortality.The underlying pathophysiological mechanisms are still not well understood.With experience and with an increase inthe number and diversity of the resulting data,the pathophysiology of laparoscopic abdominal surgery is now better understood.The normal physiology and pathophysiology of local and systemic effects of laparoscopic abdominal surgery is extremely important for safe and effective LS.Future research projects should focus on the interplay between the physiological regulatory mechanisms in the splanchnic circulation(SC),organs,and diseases.In this review,we discuss the effects of laparoscopic abdominal surgery on the SC. | Sinan Hatipoglu Sami Akbulut Filiz Hatipoglu Ruslan Abdullayev | 2014 | World Journal of Gastroenterology2014，20，48： | 5 |
| 5 | Angiogenesis and nerve regeneration induced by local administration of plasmid pBud-coVEGF165-coFGF2 into the intact rat sciatic nerve显示文摘Vascular endothelial growth factor(VEGF) and fibroblast growth factor 2(FGF2) are well-known growth factors involved in the regeneration of various tissues and organs, including peripheral nerve system. In the present study, we elucidated the local and systemic effects of plasmid construct рBud-coVEGF165-coFGF2 injected into the epineurium of intact rat sciatic nerve. Results of histological examination of sciatic nerve and multiplex immunoassays of serum showed the absence of immunogenicity and biosafety of plasmid рBud-coVEGF165-coFGF2. Moreover, local administration of plasmid DNA construct resulted in significantly decreased levels of pro-inflammatory cytokines in the peripheral blood, including tumor necrosis factor α(TNFα) and interleukin-12, and significantly increased levels of cytokines and chemokines including Regulated upon Activation, Normal T Cell Expressed and Presumably Secrete(RANTES), epidermal growth factor, interleukin-2, and monocyte chemoattractant protein 1. These changes in the peripheral blood on day 7 after injection of plasmid construct рBud-coVEGF165-coFGF2 show that the plasmid construct has systemic effects and may modulate immune response. At the same time, reverse transcriptionpolymerase chain reaction revealed transient expression of coFGF2, coVEGF165, ratFGF2 and ratVEGFA with direct transport of transcripts from distal part to proximal part of the sciatic nerve. Immunohistochemical staining revealed prolonged presence of VEGFA in sciatic nerve till 14 days post-injection. These findings suggest that local administration of plasmid construct рBud-coVEGF165-coFGF2 at a concentration of 30 ng/μL results in the formation of pro-angiogenic stimuli and, and the plasmid construct, used as a drug for gene therapy, might potentially facilitate regeneration of the sciatic nerve. The study was approved by the Animal Ethics Committee of Kazan Federal University, procedures were approved by the Local Ethics Committee(approval No. 5) on May 27, 2014. | Ruslan Masgutov Alina Zeinalova Alexey Bogov Galina Masgutova Ilnur Salafutdinov Ekaterina Garanina Valeriia Syromiatnikova Kamilla Idrisova Adelya Mullakhmetova Dina Andreeva Liliya Mukhametova Adilet Kadyrov Igor Pankov Albert Rizvanov | 2021 | Neural Regeneration Research2021，16，9： | 3 |
| 6 | Principles of equal-channel angular pressing as a processing tool for grain refinement显示文摘 | Ruslan Z. Valiev Terence G. Langdon | 2006 | Progress in Materials Science2006，，7： | 3 |
| 7 | 大塑性变形纳米结构Al-Mg合金中的形变缺陷和电子辐照效应(英文)显示文摘为澄清大塑性变形纳米结构Al-Mg合金中形变缺陷形成的本质,采用高分辨透射电子显微镜(HRTEM)研究电子辐照对高压扭转合金中面缺陷形成的影响。结果表明:对已有高密度面缺陷的HRTEM图像,经电子束照射一段时间后,这些面缺陷会完全消失;而在没有缺陷的HRTEM图像区域进行电子辐照,即使电子束的照射提高到足以在该区域击出孔洞,整个过程均未观察到任何晶格缺陷。因此,高压扭转合金中的面缺陷主要来源于极度的塑性变形,而与HRTEM观察过程中的电子辐照效应无关。 | 刘满平 孙少纯 Hans J.ROVEN 于瀛大 张桢 Maxim MURASHKIN Ruslan Z.VALIEV | 2012 | Transactions of Nonferrous Metals Society of China2012，22，8： | 3 |
| 8 | Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease显示文摘 | Clara Abraham Ruslan Medzhitov | 2011 | Gastroenterology2011，，6： | 3 |
| 9 | Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis显示文摘 | Seth Rakoff-Nahoum Justin Paglino Fatima Eslami-Varzaneh Stephen Edberg Ruslan Medzhitov | 2004 | Cell2004，，2： | 2 |
| 10 | Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis显示文摘 | Seth Rakoff-Nahoum Justin Paglino Fatima Eslami-Varzaneh Stephen Edberg Ruslan Medzhitov | 2004 | Cell2004，，2： | 2 |
| 11 | Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling显示文摘 | Jonathan C. Kagan Ruslan Medzhitov | 2006 | Cell2006，，5： | 2 |
| 12 | Special nanostructures in Al-Mg alloys subjected to high pressure torsion显示文摘Deformation twins and stacking faults were observed in nanostructure Al-Mg alloys subjected to high pressure torsion.These observations are surprising because deformation twinnings have never been observed in their coarse-grained counterparts under normal conditions.Experimental evidences are introduced on non-equilibrium grain boundaries,deformation twinnings and partial dislocation emissions from grain boundaries.Some of these features can be explained by the results reported from molecular-dynamics simulations of pure FCC metals.Special emphasis is laid on the recent observations of high density hexagonal and rhombic shaped nanostructures with an average size of 3 nm in the Al-Mg alloys processed by high pressure torsion.A possible formation process of these nanostructures is proposed based on molecular-dynamics simulations. | 刘满平 Hans J.ROVEN 刘新涛 Maxim MURASHKIN Ruslan Z.VALIEV Tamas UNGáR Levente BALOGH | 2010 | Transactions of Nonferrous Metals Society of China2010，20，11： | 2 |
| 13 | INNATE IMMUNE RECOGNITION显示文摘 | Charles A. Janeway Ruslan Medzhitov | 2002 | Annual Review of Immunology2002，，： | 2 |
| 14 | Glutathione-S-transferases genes-promising predictors of hepatic dysfunction显示文摘diseases pathogenesis are genes that encodes the synthesis of glutathione-Stransferase(GST),known as the second phase enzyme detoxification system that protects against endogenous oxidative stress and exogenous toxins,through catalisation of glutathione sulfuric groups conjugation and decontamination of lipid and deoxyribonucleic acid oxidation products.The group of GST enzymes consists of cytosolic,mitochondrial and microsomal fractions.Recently,eight classes of soluble cytoplasmic isoforms of GST enzymes are widely known:α-,ζ-,θ-,κ-,μ-,π-,σ-,andω-.The GSTs gene family in the Human Gene Nomenclature Committee,online database recorded over 20 functional genes.The level of GSTs expression is considered to be a crucial factor in determining the sensitivity of cells to a broad spectrum of toxins.Nevertheless,human GSTs genes have multiple and frequent polymorphisms that include the complete absence of the GSTM1 or the GSTT1 gene.Current review supports the position that genetic polymorphism of GST genes is involved in the pathogenesis of various liver diseases,particularly non-alcoholic fatty liver disease,hepatitis and liver cirrhosis of different etiology and hepatocellular carcinoma.Certain GST allelic variants were proven to be associated with susceptibility to hepatological pathology,and correlations with the natural course of the diseases were subsequently postulated. | Vasyl Prysyazhnyuk Larysa Sydorchuk Ruslan Sydorchuk Iryna Prysiazhniuk Kateryna Bobkovych Inna Buzdugan Valentina Dzuryak Petro Prysyazhnyuk | 2021 | World Journal of Hepatology2021，13，6： | 2 |
| 15 | INNATE IMMUNE RECOGNITION显示文摘 | Charles A. Janeway Ruslan Medzhitov | 2002 | Annual Review of Immunology2002，，： | 2 |
| 16 | How does the immune system distinguish self from nonself显示文摘 | Ruslan M Charles A Janeway Jr | 2000 | Seminars in Immunology2000，12，： | 1 |
| 17 | Molecular and expression analysis of cowpea trypsin inhibitor (CpTI) gene in transgenic Elaeis guineensis Jacq leaves显示文摘 | Ismanizan I Fong S L Ruslan A | 2010 | Aust J Crop Sci2010，4，： | 1 |
| 18 | Innate Immunity:The Virtues of a Non-clonal System of Recognition显示文摘 | Janeway Jr | 1997 | Cell1997，91，： | 1 |
| 19 | Innate immune recognition: mechanisms and pathways显示文摘 | Ruslan M Charles JJ | 2000 | Immunol Rev2000，173，： | 1 |
| 20 | Nanostructuring of metals by severe plastic deformation for advanced properties 显示文摘 | Ruslan Valiev | 2004 | Nature Mater2004，3，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员